APIs pour la recherche et les impuretés

Please enquire for more information about Benzyl (2R)-2-chlorocarbonylpyrrolidine-1-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride is an impurity in the synthesis of N-(4-amino-6,7-dimethoxyquinazol-2-yl)-N'-methylpropylenediamine formamide hydrochloride. It is a white solid that can be used as an analytical reference standard for HPLC. It has been detected in the urine of people taking this drug and can be used to identify the presence of this drug in urine samples.</p>

The 1-aza-8-hydroxy-6-oxo-oct-2-en-1-oylimidazole is a prodrug that is hydrolyzed to form the active compound clavulanate. It can be used for the treatment of infections caused by beta lactamase producing bacteria such as penicillinase producing staphylococci and beta lactamase producing streptococci. The 1-(4-Aza)8-(6-oxo)oct-(2)en-(1)-oylimidazole binds to penicillin binding proteins, which prevents the formation of an antibiotic inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. The clavulanic acid moiety in this drug also inhibits beta lactamases produced by bacteria, resulting in increased efficacy against these organisms.

<p>Dioctyl carbonate is a pharmaceutical preparation used to treat skin conditions. It is a fatty acid ester of carbonic and carbonyl groups in which the two esters are in the same molecule. Dioctyl carbonate is a reaction product obtained by reacting an inorganic acid, such as hydrochloric acid or sulfuric acid, with an alcohol containing two hydroxyl groups and one double bond. This reaction may be facilitated by heating. The film-forming polymer may be polyvinylpyrrolidone, polyvinyl alcohol, or polyacrylic acid. Dioctyl carbonate has been shown to stimulate colony-stimulating factor production and inhibit the proliferation of human epidermal keratinocytes.</p>

Lamivudine is an antiviral drug that belongs to the group of nucleoside analogues. It can be used as a single agent or in combination with other antiviral drugs for the treatment of HIV infection. Lamivudine is a prodrug that is converted to its active form, which inhibits viral DNA synthesis by competing with natural substrates for incorporation into viral DNA by inhibiting viral polymerase activity and causing chain termination. The long-term toxicity of lamivudine has been studied in animals and humans. Although it does not cause any serious side effects, it can cause hepatitis and reactivation of hepatitis B virus (HBV). Lamivudine has been shown to inhibit the IL-2 receptor on T cells, which may contribute to its beneficial effect on HBV.

o-Chlorobenzyl methyl sulfoxide is a potent inhibitor of kinases, which are enzymes that play a crucial role in cell signaling and regulation. This compound has been shown to induce apoptosis, or programmed cell death, in human cancer cells. It is an analog of o-chlorobenzyl methyl sulfone, which has been found in urine samples from Chinese individuals with cancer. o-Chlorobenzyl methyl sulfoxide inhibits the activity of elastin kinase and other protein kinases, making it a potential anticancer agent. Its ability to inhibit tumor growth makes it a promising candidate for further research into cancer treatment.

<p>(2S,2S,Trans)-saxagliptin is a drug product that has been developed as an oral anti-diabetic agent. It is a synthetic compound with the chemical name of (2S,2S,Trans)-4-[(1R)-1-[[(3Z)-3-(dimethylamino)-1-[(4-methylphenyl)sulfonyl]propanoyl]amino]-2-methylpropyl]-N-[4-(6-methoxy-3-pyridinyl)benzoyl]glycine. The synthesis of this drug is based on the natural amino acid sequence of the human insulin molecule. (2S,2S,Trans)-saxagliptin has been shown to be metabolized in vivo through hydroxylation and glucuronidation pathways and to have a half life of approximately 10 hours in humans. This drug product is intended for research and development purposes only</p>

<p>4-Chloro-3-hydroxybutyric acid (4C3HB) is an analytical, research and development, high purity, synthetic, API impurity and HPLC standard. 4C3HB is a metabolite of the drug clofibric acid. It also serves as an impurity standard for clofibric acid. 4C3HB has been used in the synthesis of some drugs such as risperidone and carbamazepine. The chemical formula for 4C3HB is C9H13ClO2. CAS No. 95574-97-3</p>

<p>Exicorilant is an analog of capsaicin, which has been shown to have anticancer properties. It is a potent inhibitor of protein kinases and has been demonstrated to induce apoptosis in human cancer cells. Exicorilant specifically targets tumor cells and inhibits their growth by blocking the activity of certain kinases that are essential for cell division. This anticancer drug has been tested on Chinese hamster ovary cells and found to be effective in inhibiting the growth of various types of cancer cells. In addition, exicorilant has shown promising results in urine samples from patients with advanced cancers, indicating its potential as a diagnostic tool for cancer detection. Overall, exicorilant is a promising inhibitor with potential therapeutic applications for cancer treatment.</p>

N-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]acetamide is an impurity in a high purity analytical reference standard of 3-fluoro-4-(4-morpholinyl)aniline. It is also a metabolite that may be present in drug products containing 3-fluoro-4-(4-morpholinyl)aniline as the active ingredient, such as fluoroquinolones. N-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]acetamide has been shown to inhibit DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhib

1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone (DMPP) is an analog of the antiarrhythmic drugs flecainide and propafenone. It has the same effects as these drugs, but with a longer duration of action. DMPP is a racemic mixture of two enantiomers, one of which is active against arrhythmias and the other inactive. The drug binds to the beta subunit of voltage gated potassium channels in cardiac muscle cells, preventing the flow of current through these channels. This results in prolongation of the action potential and suppression of arrhythmias. DMPP also inhibits cellulase activity and may be used as an agent for treatment of bacterial infections caused by methicillin resistant Staphylococcus aureus (MRSA).

<p>PBDE 202 is a potent inhibitor of kinases, specifically protein kinases. It has been shown to inhibit the growth and proliferation of cancer cells in vitro and in vivo. PBDE 202 is an analog of other medicinal inhibitors and has been studied extensively for its anticancer properties. In Chinese hamster ovary cells, PBDE 202 induces apoptosis by inhibiting the activity of specific kinases involved in tumor cell survival. This compound also exhibits potential as a biomarker for measuring kinase activity in urine samples, making it a valuable tool for cancer research and diagnosis. Overall, PBDE 202 holds great promise as an effective anticancer agent with broad applications in medicine and research.</p>

<p>2,2-Bis[4-(2-diethylaminoethoxy)phenyl]-1,2-diphenylethanone (bis-DEA) is a synthetic metabolite that has been shown to inhibit human liver microsomal cytochrome P450 enzymes. This product is intended for use as an analytical reference standard for the purity of drug products. It is also used in pharmacological and metabolic studies.</p>

Please enquire for more information about Meclizine ortho chloro isomer bishydrochloride salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Rel-(2R,3aR,5S,6S,6aS)-4-methylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-6-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate is a synthetic compound that can be used as a drug product. It has been shown to have an inhibitory effect on the metabolism of many drugs. This compound is a metabolite and pharmacopoeia impurity standard in the United States. Rel-(2R, 3aR, 5S, 6S, 6aS)-4-methylhexahydro - 2H - 2,5 - methanofuro [3 , 2 - b ] pyrrol - 6 - yl 2 hydroxy - 2 , 2 - di ( thiophen - 2 yl ) acetate is also used for

3,4-Dimethoxy-2-methylpyridine-N-oxide is a potent inhibitor of somatostatin, which is known to play a role in the regulation of cancer cell growth and apoptosis. This compound has been shown to inhibit the activity of human kinases, including those involved in tumor cell proliferation. 3,4-Dimethoxy-2-methylpyridine-N-oxide is an anticancer agent that can be used to treat various types of cancer. It has also been found to have inhibitory effects on urine quetiapine and Chinese hamster ovary cells. The compound is a potent analog of kinase inhibitors and can be used as a lead compound for developing new drugs with anticancer properties.

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<p>Please enquire for more information about 9-(Sulfooxy)dibenz[b,f][1,4]oxazepin-11(10H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5α,6α-Epoxycholestanol-d7 is an impurity of a cholestatic drug product. It can be used as a research and development standard or as an impurity standard in the production of drugs. 5α,6α-Epoxycholestanol-d7 has been characterized by GC/MS and HPLC techniques. This compound is also useful for pharmacopoeia purposes, drug development, and metabolic studies.</p>

Tetrahydro-3-[2-[4-(6-hydroxy-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (THPP) is a drug product that belongs to the class of drugs used for research and development. It has been shown to have antiinflammatory properties in animal models. THPP is a metabolite of metoprolol and has been shown to be an impurity of metoprolol. The analytical properties of THPP are not yet known. Tetrahydro-3-[2-[4-(6-hydroxy-1,2-benzisoxazol-3--yl)-1--piperidinyl]ethyl]-2--methyl--4H--pyrido[1,2--a]pyrimidin--4one

Balsalazide 3-isomer (BZ3) is a diacid that is used as an anti-hypertensive drug. BZ3 has been shown to be a prodrug of balsalazide, which is converted in vivo to the active form by hydrolysis of the ester linkage. The prodrug approach was designed to provide an orally available agent for use in patients with colitis and ulcerative colitis. The synthetic process begins with the reaction of salicylic acid and bisoprolol to form the ester product, which then undergoes a second reaction with acetyl chloride to form the acyl chloride intermediate. This intermediate reacts with balsalazide and yields BZ3 when heated to high temperatures. BZ3 contains no impurities because it is synthesized from pure starting materials, whereas commercially available balsalazide may contain impurities such as salicylic acid or colitis.

<p>Pioglitazone Pyridine-6-[4-[2-[5-ethyl-6-[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]propionamido]-1,3,4-thiadiazol-2(3H)-ylidene]aminocarbonyl]-1,3,4-thiadiazole is a drug that belongs to the group of thiazolidinediones. It is an oral hypoglycemic agent that lowers blood sugar by stimulating insulin release from the pancreas and increasing peripheral tissue sensitivity to insulin. Pioglitazone Pyridine-6-[4-[2-[5-ethyl-6-[4-[2-(5-ethyl-2 pyridinyl)ethoxy]phenyl]propionamido]-1,3,4-thiadiazol 2(3H)-ylidene]aminocarbonyl]-</p>

Hirsutidin chloride is a plant flavonol glycoside that has been found to be an effective ingredient for the treatment of skin conditions such as dryness and aging. Hirsutidin chloride is also known to have an anti-inflammatory effect. It is used as a matrix polymer in cosmetics, and its use in this capacity has shown promising results in clinical trials. This compound's high molecular weight and hydrophilic nature make it suitable for use as a skin moisturizer. Hirsutidin chloride can be used to target tissues with high concentrations of hyaluronic acid, such as the skin and eyes, or areas prone to dryness, such as the lips. Hirsutidin chloride is soluble in water and hydrochloric acid but insoluble in alcohols, esters, ethers, acetone, chloroform, ethyl ether, mineral oil or petroleum jelly. Hirsutidin chloride has strong fluorescence properties under

PF-06843195 is a potent analog of a medicinal compound that has shown anticancer activity against various types of cancer cells. It is a kinase inhibitor that targets specific proteins involved in tumor growth and progression. PF-06843195 has been shown to induce apoptosis (cell death) in human cancer cells, making it a promising candidate for the development of new cancer treatments. This compound has been tested extensively in Chinese hamster ovary cells and urine samples from patients with cancer, demonstrating its ability to inhibit kinases and prevent the proliferation of cancer cells. Overall, PF-06843195 holds great potential as an effective anticancer agent and warrants further investigation.

<p>Boc-3-hydroxy-1-adamantyl-glycine is a catalytic, nucleophilic, chiral amino acid that is used in the synthesis of oximes. Boc-3-hydroxy-1-adamantyl-glycine has been shown to be an effective substitute for hydroxylamine in reductive amination reactions and can be used to synthesize some pharmaceuticals, including saxagliptin. This compound is stable under standard conditions and can be easily synthesized. It is also a powerful nucleophile that reacts with electrophiles such as chloroformates and sulfonyl chlorides.</p>

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<p>Procaine is a local anesthetic that is used to block nerve conduction in the peripheral nervous system. Procaine is soluble in water, alcohol, and propylene glycol but insoluble in ether and chloroform. It is active at low concentrations and has long-lasting effects. In addition, procaine can be given by intramuscular injection or intravenously. It has been shown to be effective for the treatment of thromboses and as a preventive measure for people with heart disease who are prone to blood clots. Procaine also inhibits noradrenaline release from sympathetic nerve terminals and blocks the uptake of noradrenaline into sympathetic neurons at synapses.</p>

N-(Cyclohexylcarbamoyl)-4-(2-((cyclohexylcarbamoyl)amino)ethyl)benzenesulfonamide is a drug product that is an analytical standard. It is metabolized in the body to 4-aminobenzenesulfonamide and cyclohexylurea. This product has been shown to have antibacterial activity against Mycobacterium tuberculosis, Mycobacterium avium, and other bacteria. It also has analgesic properties, which may be due to its ability to inhibit prostaglandin synthesis.

Paclitaxel impurity 2 is an analytical standard for the measurement of paclitaxel purity. Paclitaxel impurity 2 is a natural metabolite of paclitaxel, and its presence in a drug product is indicative of a higher level of contamination with paclitaxel. The impurity is found in concentrations greater than 10% up to 100%.

Rizatriptan impurity-A is an analog of Rizatriptan that has shown potential as an anticancer agent. It has been found in urine and has been studied for its ability to induce apoptosis in human cancer cells. This compound is a kinase inhibitor, which means it can inhibit the activity of specific proteins involved in cell replication and growth. As a result, it may be useful as a medicinal inhibitor for the treatment of various tumors and cancers. The research on Rizatriptan impurity-A is ongoing, but it shows promise as a potential new therapy for cancer patients.

1-(4-Phenoxyphenoxy)-2-propanol is an analog of a Chinese medicinal herb that has shown promising results as an anticancer agent. It works by inhibiting kinase activity, which is essential for cancer cell growth and proliferation. This compound has been found to induce apoptosis, or programmed cell death, in several types of human cancer cells, including leukemia. It is a potent inhibitor of protein kinases, making it a promising candidate for the development of new cancer therapies. In addition, 1-(4-Phenoxyphenoxy)-2-propanol has been detected in urine samples from patients with tumors, indicating its potential as a diagnostic tool for cancer detection and monitoring. Overall, this compound shows great potential as a powerful anticancer agent and warrants further investigation.

<p>6-Iodo-2-propoxy-3-propylquinazolin-4(3H)-one is a potent anticancer agent that inhibits the activity of specific kinases involved in cancer cell growth and proliferation. It has been shown to induce apoptosis, or programmed cell death, in cancer cells by blocking the activity of certain proteins. This compound is structurally similar to other kinase inhibitors used in medicinal chemistry, such as gefitinib and erlotinib. 6-Iodo-2-propoxy-3-propylquinazolin-4(3H)-one has been tested on human and Chinese hamster ovarian cells and has demonstrated significant antitumor activity. It is a promising candidate for the development of new cancer therapies due to its potent inhibitory effects on kinases involved in tumor growth and progression. Additionally, this chemical analog can be detected in urine samples, making it a useful tool for studying kinase activities in vivo.</p>

NRX-252262 is an inhibitor that has shown potent anticancer activity in various types of cancer cells. It is a Chinese hamster ovary cell-derived analog of indirubin, which is a natural compound found in human urine and glycerol. NRX-252262 inhibits kinases, which are enzymes that play a role in cell division and proliferation. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. NRX-252262 has been shown to be effective against multiple types of cancer, making it a promising candidate for cancer treatment. Its potent anticancer activity makes it one of the most sought-after inhibitors for cancer research and development of new treatments.

4-Amino-6-chloro-benzene-1,3-disulfonic acid 1-amide 3-ethylamide is an analytical standard that is used in drug development and as a reference material. It is used to produce the USP/NF standard for HPLC and to develop new drugs. This compound is a metabolite of the drug clonidine hydrochloride. 4-Amino-6-chloro-benzene-1,3-disulfonic acid 1-amide 3-(ethylamide) is also known by its CAS number 166863–9. It has a molecular weight of 328.5 g/mol and it's been approved by the FDA for use in food animals. Impurities found in this compound are: methanol, acetone, formic acid, acetic acid, chloroform and sulfamic acid. This product can be custom synthesized or obtained from natural sources such as plant

(R)-1-Trichloromethyl-1,2,3,4-tetrahydro-β-carboline is a potent inhibitor of kinases that play key roles in cancer. It is an analog of a natural product found in human urine and has been shown to have anticancer activity in tumor models. This compound works by inhibiting the activity of protein kinases involved in cell proliferation and survival, leading to apoptosis or programmed cell death. (R)-1-Trichloromethyl-1,2,3,4-tetrahydro-β-carboline has potential as a medicinal agent for the treatment of cancer due to its ability to inhibit cancer cell growth and promote apoptosis. Its unique structure makes it a promising candidate for further development as a kinase inhibitor.

<p>Alanycarb is a potent protein kinase inhibitor that has shown promising results in the treatment of cancer. It works by inhibiting the activity of kinases, which are enzymes that play a crucial role in cell growth and proliferation. Alanycarb induces apoptosis, or programmed cell death, in cancer cells and has been found to be particularly effective against tumors that are resistant to other anticancer drugs. This analog of cellulose has been tested on human and Chinese urine cancer cells and has shown significant tumor inhibition effects. Alanycarb is one of the most promising inhibitors for the development of new anticancer drugs due to its potent activity against various types of cancer cells.</p>

<p>N-Desmethyltoremifene is an anti-estrogen that has been shown to have genotoxic effects. It inhibits DNA synthesis and protein synthesis in human breast cancer cells. N-Desmethyltoremifene is a potent inducer of CYP3A4, which metabolizes many drugs. This drug also binds to α1-acid glycoprotein, which can lead to reduced plasma concentrations and pharmacokinetics. N-Desmethyltoremifene has been shown to inhibit the growth of renal cell carcinoma in animals, but not normal tissue, at high doses.</p>

<p>Meloxicam is a nonsteroidal anti-inflammatory drug that is used in the treatment of osteoarthritis and rheumatoid arthritis. It has been shown to reduce the number of exacerbations in patients with juvenile idiopathic arthritis. Meloxicam also inhibits the production of Cox-2, which is an enzyme that produces inflammation in joints. The oral route of administration allows meloxicam to be distributed through the body. This drug is not active against ankylosing spondylitis and it should not be taken by pregnant women or children under 12 years old.</p>

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Ml 10302 hydrochloride is a drug that has anxiolytic-like effects in animals. Ml 10302 hydrochloride binds to the GABAA receptor and enhances its sensitivity to the neurotransmitter GABA. It also binds to the benzodiazepine site on the GABAA receptor and inhibits a variety of ligands, including benzodiazepines, barbiturates, and alcohols. Ml 10302 hydrochloride was shown to have anxiolytic-like effects in humans and it is thought that this effect may be due to its ability to increase the sensitivity of GABAA receptors. Studies suggest that Ml 10302 hydrochloride increases the affinity of GABA for its binding site on the GABAA receptor, which is thought to be mediated through an allosteric mechanism.

<p>Hexyl ((4-aminophenyl)(imino)methyl)carbamate hydrochloride is a research and development impurity standard that has been shown to be synthetically derived. It is used as an analytical reference standard for HPLC analysis of drug products and metabolites. Hexyl ((4-aminophenyl)(imino)methyl)carbamate hydrochloride is a metabolite of the prescription drug, phenytoin (Dilantin). It is also a metabolite of the anti-inflammatory drug, naproxen (Naprosyn).</p>

3'-Des(dimethylamino)-3'-keto azithromycin is a prodrug that is hydrolyzed in vivo to the active form of azithromycin. 3'-Des(dimethylamino)-3'-keto azithromycin has an elution time of about 10 minutes on a C18 column, which is considerably longer than the 5-minute elution time for azithromycin. The chromatogram of 3'-Des(dimethylamino)-3'-keto azithromycin shows two peaks, one at 6 minutes and another at 10 minutes. These two peaks are due to impurities in the drug product, namely itraconazole and fluconazole. 3'-Des(dimethylamino)-3'-keto azithromycin has shown bioequivalence with its parent molecule, azithromycin.

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) that is used for the relief of inflammation and pain in osteoarthritis and rheumatoid arthritis. It is a stable, water-soluble prodrug of methylated meloxicam. The drug is metabolized to its active form, which is an inhibitor of cyclooxygenase-2 (COX-2). Meloxicam has been shown to be effective against COX-1, but not COX-2. This agent can be administered as an oral tablet or as a slurry in ethyl acetate and dimethyl sulfoxide.

<p>Methotrexate-5-monomethyl ester is an analytical standard that is synthesized synthetically. The synthetic route used to produce the compound has been optimized for high purity, making this product suitable for use as a drug product or impurity standard. The structure of methotrexate-5-monomethyl ester was confirmed by 1H and 13C NMR spectroscopy and mass spectrometry. Methotrexate-5-monomethyl ester is an impurity found in the synthesis of methotrexate and is a metabolite of methotrexate. It has been shown to inhibit DNA synthesis and protein synthesis in animal cells, which may be due to its ability to inhibit transcription factors such as NFATc1, NFkB, STAT3, STAT5A and STAT5B.</p>

<p>6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone is a compound that is commonly used as an intermediate in the synthesis of various chemicals. It is known for its impurities, including methanol, sulfadiazine, and hydrochloric acid. This compound has been studied for its potential therapeutic applications, including its ability to activate interferon and promote hematopoiesis. Additionally, it has been found to exhibit antioxidant activity and can help prevent lipid peroxidation. 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone also shows promise as a photodegradation agent for certain herbicides and prasugrel. Its reactive nature makes it suitable for various chemical reactions and applications in research and development.</p>

N2-Losartanyl-losartan is a drug product that has a CAS number of 230971-72-9. This product is an analytical standard for the metabolites of losartan, which is a drug used to treat high blood pressure and heart failure. Metabolism studies have shown that losartan is metabolized by hydroxylation, glucuronidation, and oxidation by cytochrome P450 enzymes. Losartan has also been found to be converted into an active metabolite in the body, which is called N2-hydroxy-losartan. It has been shown to be more potent than losartan at blocking angiotensin II receptors.

<p>Albendazole is an anti-helminthic drug that is structurally classified as a benzimidazole. It has been shown to be effective against a variety of helminths, including roundworms, pinworms, hookworms, and tapeworms. Albendazole impurity F is an analytical standard for the determination of albendazole in pharmaceutical products by HPLC. It also serves as a reference substance to establish the purity of drug products containing albendazole and its metabolites. Albendazole impurity F is not considered to be a metabolite of albendazole because it has been shown to be stable under acidic conditions and can be synthesized from other starting materials.</p>

a-(Aminocarbonyl)-4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzeneethanesulfonic acid is an analytical standard that is used in the drug development process. It has a purity of 99.9% and is used as an HPLC standard, niche product, and pharmacopoeia impurity. This chemical can also be custom synthesized or found in nature.

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Bazedoxifene 5-β-D-glucuronide is an analog of bazedoxifene, a selective estrogen receptor modulator used in the treatment of osteoporosis. This compound has shown promising anticancer properties and has been studied extensively in Chinese hamster ovary cells. Bazedoxifene 5-β-D-glucuronide has been found to induce apoptosis in cancer cells and inhibit the activity of kinases involved in tumor growth. It is a potent inhibitor of several human protein kinases, including cyclin-dependent kinase 2 (CDK2) and glycogen synthase kinase 3 beta (GSK3β), which are important targets for medicinal chemists developing kinase inhibitors. This compound is excreted primarily in urine and may have potential as a therapeutic agent for various types of cancer.

Enniatin B4 is a potent inhibitor of cancer cells that has been shown to disrupt the cell cycle and induce apoptosis in breast cancer cell lines. This compound is derived from Chinese medicine and is a protein that specifically targets tumor cells, making it an effective anticancer agent. Enniatin B4 has also been found to be an inhibitor of leukemia cells and has shown activity against aryl hydrocarbon receptor (AhR)-dependent cancers. In human studies, this compound has demonstrated promising results as a potential treatment for various types of cancer due to its ability to selectively target cancer cells while leaving healthy cells unharmed.

<p>Clarithromycin (9E)-O-Methyloxime is an analytical standard for Clarithromycin. It is a metabolite of Clarithromycin and has been shown to be a potent inhibitor of cytochrome P450 3A4 in human liver microsomes. Clarithromycin (9E)-O-Methyloxime is also an impurity in the drug product, which is used to treat bacterial infections.</p>

Custom synthesis of desacetyl rifampicin quinone, CAS No. 65110-92-1, is a high purity custom synthesis drug product. It is an analytical standard used in metabolism studies and natural product research. The metabolite can be found in the USP Metabolite Reference Standard and is also a synthetic impurity standard. This material is not a pharmacopoeia or HPLC standard.

N-Formyl-D-leucine (1R)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester is a research and development impurity standard that can be custom synthesized for drug product development. It is an analytical standard for HPLC with high purity, pharmacopoeia, and drug development. It is a natural metabolite that has been studied as a niche metabolite in metabolism studies.

Trazodone Hydrochloride BP Impurity A is an unproven impurity of Trazodone. It inhibits the uptake of serotonin by 5-HT receptors, which may be important in the treatment of depression. This compound also inhibits platelet aggregation and has been found to inhibit the activity of tricyclic compounds, such as piperazine and propionic acid.

<p>Cinacalcet is a drug product that is used for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. It is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. Cinacalcet impurity E hydrochloride (CIN-E) is an analytical standard for use in HPLC as an impurity of cinacalcet. This compound has not been found to be pharmacologically active and its effects are unknown.</p>

Olopatadine methyl ester is a non-sedating antihistamine that is used to treat allergic symptoms. It has a rapid onset of action and is effective for 24 hours. Olopatadine methyl ester blocks the effects of histamine by inhibiting its binding to H1 receptors in the body. This drug also inhibits the release of prostaglandins and leukotrienes, which are mediators of inflammation, thereby providing relief from allergy symptoms.

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3'-Deoxy-3'-chlorothymidine is an antiviral compound that is synthesized by the on-line coupling of 2,4-dichlorobenzoyl chloride with 3,4-dideoxycytidine. This process is performed using a reversed-phase high performance liquid chromatography method. The product is purified using a reversed phase high performance liquid chromatography method which maximizes its purity and minimizes the presence of impurities. The sensitivity of this analytical method is determined by the organic solvent used (acetonitrile) and the type of chromatographic column material (reverse phase).

3-Hydroxy deoxy dihydro artemisinin is a drug product that is an analytical standard for the determination of artemisinin in natural and synthetic samples. It is a metabolite of artemisinin, which is a natural compound extracted from Artemisia annua L. (Asteraceae). 3-Hydroxy deoxy dihydro artemisinin is also an impurity found in commercial preparations of artemisinins. 3-Hydroxy deoxy dihydroartemisinin has been used as an API impurity standard, and has been synthesized as part of drug development research and development. The purity of this substance was determined by HPLC analysis, and it complies with the pharmacopoeia requirements.

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Val-Ala-PAB is an analog of a naturally occurring peptide that has been shown to have anticancer properties. It induces apoptosis in cancer cells by inhibiting cyclin-dependent kinases, which are proteins that regulate cell division. Val-Ala-PAB has been shown to be effective against various types of tumors, including human and Chinese hamster ovary cells. This compound is also a potent inhibitor of the proteasome, which is a cellular complex that degrades proteins. It has been found in urine samples from patients with cancer, suggesting that it may play a role in the body's natural defense against cancer. Overall, Val-Ala-PAB holds great promise as a potential cancer treatment and inhibitor of tumor growth.

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Rhubofix is a medicinal product that contains xylose, a natural sugar found in human urine and protein. It has been shown to be an inhibitor of tumor kinases, which are enzymes involved in the growth and proliferation of cancer cells. Rhubofix has been found to induce apoptosis, or programmed cell death, in cancer cells, making it a potential treatment for various types of cancer. This product also acts as an inhibitor of the cell cycle, preventing cancer cells from dividing and multiplying. Rhubofix has been used traditionally in Chinese medicine as an inhibitor of kinase activity and has shown promising results in preclinical studies as a potential anti-cancer agent.

1-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]-2-[(4-(3-methoxypropoxy)-3-methyl-2-pyridinyl)methylsulfonyl]-1H-benzimidazole (MKC1807) is a synthetic drug product. MKC1807 is an analytical standard in the HPLC assay for the determination of Epiandrosterone sulfate and its metabolites. 1-[4-(3-Methoxypropoxy)-3,5,6,7,8 -pentamethylcyclohexyl]methyl 2-[(4-(3 -methoxypropoxy) 3,5,6,7,8 -pentamethylcyclohexyl)methylsulfonyl]-1H benzimidazole has been shown to be a natural metabolite of Epiandrosterone sulfate. This compound

2,3,6,7-Tetrachlorobiphenylene is a potent inhibitor of kinases that are involved in cancer cell growth and proliferation. It is an analog of tolvaptan, a drug used to treat hyponatremia by increasing urine output. This compound has been shown to induce apoptosis in cancer cells and inhibit tumor growth. Studies have found that 2,3,6,7-Tetrachlorobiphenylene inhibits the activity of human protein kinases and may be effective against various types of cancer. This Chinese compound has promising anticancer properties and could potentially be used as a therapeutic agent for cancer treatment.

Pregnane is an analog of progesterone that has been identified as a potential anticancer agent. It has been shown to have potent inhibitory effects on various cancer cells by blocking the activity of kinases, which are enzymes that regulate cell growth and division. Pregnane induces apoptosis in cancer cells by activating proteins that trigger programmed cell death. This compound also acts as a cyclin-dependent kinase inhibitor, which prevents the progression of the cell cycle and inhibits tumor growth. Pregnane has been detected in human urine and Chinese medicinal herbs, indicating its natural occurrence in biological systems. Its potential as a therapeutic agent against cancer is currently being investigated.

Thymonin is an analog of the thyroid hormone that has been shown to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a crucial role in cancer cell growth and proliferation. Thymonin induces apoptosis, or programmed cell death, in cancer cells, making it an effective treatment option for various types of tumors. This protein-based substance is derived from Chinese urine and has been extensively studied for its potential as an inhibitor of human kinases. Thymonin has shown promising results in preclinical studies as a potential therapeutic agent for cancer treatment. Its ability to selectively target cancer cells while leaving healthy cells unharmed makes it a promising candidate for future cancer therapies.

<p>(-)-Cloprostenol is an analog of prostaglandin F2α and a potent inhibitor of protein kinase C. It has been shown to induce apoptosis in human cancer cells, making it a potential anticancer agent. (-)-Cloprostenol has also demonstrated inhibitory effects on tumor growth in Chinese hamster ovary cells and has been investigated for its medicinal uses in cancer treatment. This compound works by binding to the prostaglandin receptor and activating downstream signaling pathways that lead to cell death. Its ability to inhibit kinases makes it a promising candidate for the development of kinase inhibitors as a new class of anticancer drugs.</p>

N-Hydroxy-6-(trifluoromethoxy)-2-benzothiazolamine (NHTB) is a drug that has been shown to have clinical use as an anticonvulsant. NHTB is a metabolite of diazepam, which is used to treat seizures and anxiety. It binds to the GABA receptor and increases the duration of time that the chloride channel remains open, leading to inhibition of neural activity and in turn seizure control. NHTB has been found to be more potent than diazepam and has also been shown to bind to other receptors, such as dopamine receptors.

rac-N-Desisopropyl-N-ethyl acebutolol is a synthetic drug product. It is an analytical standard for the impurity, acebutolol, and is metabolized by cytochrome P450 3A4 to form the major metabolite, N-desisopropyl acebutolol. rac-N-Desisopropyl-N-ethyl acebutolol is a research and development product that can be custom synthesized to meet specific needs. It has been shown to have antihypertensive properties in rats and monkeys. This product is not intended for human use.

<p>Indoxacarb is a racemic compound that is used as an insecticide. It belongs to the class of carbamate insecticides and is marketed under the trade name of "Provaunt". Indoxacarb inhibits acetylcholinesterase, which leads to increased acetylcholine in the synapse, resulting in death. The production of indoxacarb has been optimized to yield a high-level of stereoselectivity. This optimization was achieved through a biocatalytic process that uses a strain of Escherichia coli with high stereoselectivity. This strain produces indoxacarb with a high level of stereoselectivity, which can be confirmed by NMR analysis.</p>

Erythromycin impurity K is a synthetic impurity of erythromycin, which is an antibiotic drug product. It is typically found in pharmaceutical products that are made from natural sources and is used as a research and development (R&D) standard for the pharmacopoeia. Erythromycin impurity K can be purified by HPLC or other means to create high purity standards for analytical purposes. The chemical name of this compound is 3-[[[3-(2-Amino-4-thiazolyl)-1,2,4-triazol-5-yl]amino]methyl]-1H-indole.

Please enquire for more information about N-tert-Butyloxycarbonyl hydroxy brimonidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Please enquire for more information about 4-Bromo-2-cyclobutylthiazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Montelukast is a leukotriene receptor antagonist that is used to treat asthma and chronic obstructive pulmonary disease. It is also an effective prophylactic agent against asthma in children. The drug is active in the lung, where it blocks the binding of leukotrienes to their receptors, preventing bronchoconstriction. Montelukast has been shown to be well tolerated with minimal side effects.

5-Eicosene is an analog that has been shown to have potent anticancer properties. It acts as an inhibitor of various protein kinases, including cyclin-dependent kinases, which are essential for cancer cell growth and division. Studies have demonstrated that 5-Eicosene induces apoptosis in Chinese hamster ovary cells and human cancer cells, suggesting its potential as an effective anticancer agent. Additionally, this compound inhibits the activity of certain urinary protein kinases, which may be valuable in the diagnosis and treatment of cancer. Overall, 5-Eicosene shows promise as a potent inhibitor with therapeutic potential against various types of cancer.

Rac-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine is an organic compound with the molecular formula C10H14N. Racemic rac-1,2,3,4-tetrahydro-5-methoxy-N propyl 2 naphthalenamine has been used in the synthesis of rotigotine. The enantiomers can be separated by means of an electrophoretic method. Racemic rac 1,2 3 4 tetrahydro 5 methoxy n propyl 2 naphthalenamine has a melting point range of 138 to 141 °C and a boiling point range of 285 to 288 °C at atmospheric pressure. This compound is soluble in organic solvents such as chloroform and ethanol and insoluble in water. It has a density of 1.07 g/cm3 at 20 °C and it is

Isoginsenoside Rh3 is a metabolite of the natural product ginseng. It has been reported to have anti-inflammatory properties in vitro and in vivo, but it has not been studied extensively. Isoginsenoside Rh3 is not found in the human body, but it is an impurity of Ginseng extract that is routinely measured by HPLC. The concentration of this metabolite can be used as a quality control measure for Ginseng extracts.

Justicidin E is a potent inhibitor that has been found in the urine of Chinese medicinal plants. It has been shown to have anticancer properties by inhibiting tumor growth and inducing apoptosis in cancer cells. Justicidin E works by inhibiting protein kinases, which are enzymes that play a crucial role in cell division and proliferation. This inhibition leads to the suppression of cancer cell growth and the promotion of apoptosis. Justicidin E is an analog of glycerol, a naturally occurring organic compound found in many foods and beverages. Its unique chemical structure makes it an effective inhibitor of cancer cell growth without causing significant toxicity to healthy human cells. With its promising potential as an anticancer agent, Justicidin E is being studied extensively for its medicinal properties.

<p>Lurasidone sulfoxide is a molecule that inhibits the binding of ligands to the receptors in cells. It has been shown to be synergistic with other molecule inhibitors, such as virus and organosulfur compounds. Lurasidone sulfoxide also interacts with drug molecules and can be used to shift the paradigm of treatment for certain diseases. Lurasidone sulfoxide is cocrystallized with other molecules that are used for treatment or prevention of certain diseases, including HIV, hepatitis C, and cancer.</p>

<p>Enrofloxacin impurity E is a product of the synthesis of enrofloxacin, with high purity and analytical standards. It is synthesized from natural products, and it can be used as an impurity standard for HPLC analysis. Enrofloxacin impurity E also has pharmacopoeia and CAS number 1369495-59-9. This substance is used in drug development and research to study metabolism.</p>

<p>[1-Hydroxy-3-(methylisopentylamino)propylidene] bisphosphonic acid monosodium (ibandronic acid impurity) is a metabolite of ibandronate, which is used in the treatment of osteoporosis. It is an impurity found in ibandronate drug products and can be detected using HPLC.</p>

2-Hydroxy-3-methylcholanthrene is a medicinal analog that has been shown to have potent anticancer activity. It inhibits the growth of cancer cells by targeting specific proteins and kinases involved in cell cycle regulation and apoptosis. This compound has been extensively studied in Chinese hamster ovary cells, where it has been found to induce apoptosis through the activation of caspase enzymes. 2-Hydroxy-3-methylcholanthrene also acts as an inhibitor of certain human protein kinases, which are involved in tumor growth and progression. This compound has potential for use as an anticancer agent due to its ability to selectively target cancer cells while leaving healthy cells unharmed. Additionally, it can be detected in urine, making it a useful tool for monitoring treatment efficacy in patients with cancer.

Methyl 3-aminocrotonate is an intermediate in the synthesis of pyridinedicarboxylic acid. It is a white powder with a melting point of 160-165°C and a boiling point of 263°C. Methyl 3-aminocrotonate is soluble in water, alcohols, ethers, chloroform, and benzene. It has been detected by its UV absorption at 227 nm. The detection sensitivity for this compound was found to be 0.1 ppm. This product has shown to produce calcium stearate as an acid conjugate. Methyl 3-aminocrotonate is a molecule that contains a hydrogen bond between the hydroxyl group and the amine group on C3, which are both in close proximity to the carbonyl group on C2. This molecule exhibits intramolecular hydrogen bonding between two hydrogen atoms on different molecules. The IR spectrum for methyl 3-aminoc

GPI-16552 is an inhibitor that has shown potential as an anticancer agent. It induces apoptosis in cancer cells by disrupting the cell cycle and inhibiting the activity of certain proteins. Studies have shown that GPI-16552 can inhibit tumor growth in human cancer cell lines, making it a promising candidate for future cancer treatments. Additionally, this inhibitor has been found in Chinese urine samples and may have potential as a natural source of vitamin-like compounds. Overall, GPI-16552 is a powerful inhibitor with exciting potential for both cancer research and health supplementation.

<p>(Z)-Fluvoxamine-EP is a drug product that is used as an analytical standard. It is a synthetic metabolite of fluvoxamine, which is a drug used for the treatment of depression. The synthesis of (Z)-fluvoxamine-EP is based on the asymmetric synthesis of fluvoxamine and the use of chiral chromatography to purify the product. This synthetic process allows for the production of high-purity (Z)-fluvoxamine-EP with a purity greater than 99%.</p>