APIs pour la recherche et les impuretés

Dihydroxy bendamustine sodium salt is a medicinal protein analog that has been shown to be effective in the treatment of various types of cancer. It works by inhibiting certain kinases that are involved in tumor growth and promoting apoptosis, or programmed cell death, in cancer cells. This drug has been found to be effective against amphetamine-resistant Chinese hamster ovary cells and has shown promising results in clinical trials for the treatment of different types of cancer. Dihydroxy bendamustine sodium salt is excreted primarily through urine and is considered to be a potent inhibitor of kinase activity. Its potential as an anticancer agent makes it an important tool for cancer research and treatment.

Fluticasone propionate dithioacid is a synthetic corticosteroid that has anti-inflammatory and anti-allergic effects. It binds to the glucocorticoid receptor, which prevents the release of inflammatory mediators. Fluticasone propionate dithioacid is used in research and development, as well as for custom synthesis and drug product development. This compound has been shown to have high purity and is often used as a pharmacopoeia or drug development standard. Metabolism studies have also been conducted on this compound.

3-amino-2,6-dimethoxy-4-(4-amino-7-hydroxy-6-methoxyquinazolin-2(1H)-yl)piperazine (DMQA) is a synthetic compound. It is a racemate with two stereoisomers, which are mirror images of each other. The two stereoisomers have been characterized and the data for the two stereoisomers are provided in the table below.

<p>1-(4-((2,4-dimethylphenyl)thio)phenyl)piperazine hydrobromide is a synthetic drug that has been used in the research and development of drugs. It is a metabolite of 1-(4-((2,4-dimethylphenyl)thio)-phenyl)piperazine (1DMPP). The impurity standard for 1-(4-((2,4-dimethylphenyl)thio)-phenyl)piperazine hydrobromide is 0.5% (w/w). It has been shown to be effective in metabolism studies.</p>

<p>Labetalol is a carboxylic acid that is used as a drug to lower blood pressure. It belongs to the group of beta-blockers and has been shown to have anti-inflammatory properties. Labetalol is a monomer that can be polymerized into homopolymers or copolymers with other monomers, such as styrene, methyl methacrylate, and acrylonitrile. Labetalol has the ability to polymerize by radical polymerization. The molecular weight of labetalol ranges from 500-2000 Da and it can be used in the preparation of phosphorylcholine which is an important constituent of cell membranes.</p>

<p>Granisetron is a drug that belongs to the group of serotonin receptor antagonists. It is used as an antiemetic, mainly in the prevention and treatment of nausea and vomiting caused by cancer chemotherapy and surgery. This drug has been shown to be effective in controlling nausea and vomiting, even when given after chemotherapy or surgical procedures. Granisetron hydrochloride was synthesized in 1988 by chemists at Hoffmann-La Roche. The synthesis was patented in 1990. Potential impurities are not listed on the USP or EP pharmacopeia, but these impurities have been detected during synthesis.</p>

Please enquire for more information about 6,7-Dihydro canrenone lactol including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Tc 1698 dihydrochloride is a tumor-promoting agent that inhibits the growth of tumor tissues. It has been shown to inhibit the proliferation of human retinal pigment epithelial cells in vitro, which may be due to its ability to induce flavanones. Tc 1698 dihydrochloride can also act as an inducer for the production and release of cytokines, such as IL-6, IL-8 and monocyte chemoattractant protein 1. This agent has been shown to promote angiogenesis and stimulate collagen synthesis in skin fibroblasts.</p>

<p>Anastrozole is an aromatase inhibitor used in the treatment of breast cancer. It is a synthetic drug and impurity standard for HPLC analysis, pharmacopoeia monograph, and synthetic drug development. This product is a mixture of two stereoisomers - the active form, 4-hydroxyanastrozole (4HA), and the inactive form, 4-oxo-anastrozole (4OA). The purity of this product is &gt;99% with a melting point of 130°C.</p>

Rotogotine EP Impurity J is a synthetic drug that is metabolized to produce the active form, rotogotine. Rotogotine is used in the treatment of Parkinson's disease and restless leg syndrome. This impurity standard may be used as a reference for analytical methods such as HPLC or GC.

<p>Please enquire for more information about Carbidopa 4-phosphate trihydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Phenothiazines are antipsychotic drugs that belong to the thioxanthene class. N,N,α-Trimethyl-10H-phenothiazine-10-acetamide is a research and development impurity standard for pharmacopoeia drug product. It is a synthetic compound that is used in drug development and metabolite analysis. This chemical has been shown to have niche applications in metabolism studies and analytical work. It also has a high purity and is used as an HPLC standard. CAS No. 86382-43-6</p>

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<p>Sulfo EGS is a potent analog that has shown promising anticancer activity in various human cancer cell lines. It works by inhibiting kinases, which are enzymes that play a key role in the regulation of cellular processes such as proliferation, differentiation, and apoptosis. Sulfo EGS has been found to be particularly effective against Chinese hamster ovary cells and tumor cells from medicinal plants. This inhibitor also shows potential for use in the development of kinase inhibitors for cancer therapy. In addition, Sulfo EGS is commonly used as a cross-linking reagent to covalently link proteins or protein complexes in urine or other biological samples for further analysis. Overall, Sulfo EGS is an important tool for cancer research and drug development.</p>

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<p>O-Desmethyl mycophenolate mofetil (ODMM) is a metabolite of mycophenolic acid, a drug that is used to treat immunosuppressive diseases. ODMM can be synthesized in the laboratory and used as an analytical standard for mycophenolic acid and its metabolites. ODMM is also a metabolic product of mycophenolate mofetil, which has been shown to have anti-inflammatory properties.</p>

<p>4-Methanesulfonyloxybutanol is a chemical substance with the molecular formula CH3SO2CH(CH2OH)CH2OH. It is used as an intermediate in the synthesis of 4-methanesulfonyloxybutanol, which is a potent inhibitor of busulfan-induced leukopenia and myelosuppression. This substance has been shown to be highly effective in preventing busulfan-induced side effects when administered intravenously. 4-Methanesulfonyloxybutanol is chemically synthesized by intramolecular alkylation of butanol, followed by hydrolysis. The reaction product can be detected using an ionization detector in conjunction with gas chromatography. This product is an alkylation agent that reacts with polypropylene to produce polypropylene glycols.</p>

<p>1,2,3,4-Tetrahydro-4,6,7-isoquinolinetriol hydrochloride is a drug product. It is a synthetic compound that is metabolized to form metabolites. The natural product was isolated from an extract of the roots of Valeriana officinalis L. and has been used as a sedative and hypnotic in traditional medicine. 1,2,3,4-Tetrahydro-4,6,7-isoquinolinetriol hydrochloride has also been shown to have anti-inflammatory activities in human chondrocytes. This drug product is used in research and development for the treatment of neurodegenerative diseases such as Parkinson's disease.</p>

<p>2-[[(4-Chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole (CAS No. 168167-42-8) is a synthetic compound that is used as an analytical reference standard for HPLC. It is also used in the study of drug metabolism, and it has been shown to induce natural oxidation in vitro. 2-[(4-Chloro-3-methylpyridinium)methylsulfinyl]-1Hbenzimidazole is an impurity found in pharmaceutical products that are synthesized from 1-(2,4,6trichlorophenyl)-3-[(4chloromethyl)phenyl]urea.</p>

<p>Impurity G is an impurity found in the drug Iohexol. It is a synthetic, amide, propylamine, diacetate and methyl anthranilate. Impurity G has been shown to be a catalyst for the production of iodinated contrast media with high yield. This can be used to make the drug Moxifloxacin hydrochloride, which is used to treat bacterial infections such as pneumonia and bronchitis caused by Legionella pneumophila or Mycoplasma pneumoniae. The chemical compound moxifloxacin has anti-inflammatory properties that are due to its ability to inhibit prostaglandin synthesis.</p>

<p>((E)-5-((M-[(2-Carboxyethyl)carbamoyl]phenyl)azo)-2-salicylic acid) is a drug product. It is a synthetic, white to off-white powder that has a molecular weight of 246.9 g/mol and an assay of 99%. The impurity standard for this product is (E)-5-(4-(methylsulfonyl)phenylazo)-2-salicylic acid.</p>

Tyropanoate sodium is a radiocontrast agent that is used to produce images in diagnostic procedures. It is used as a contrast agent for X-rays and magnetic resonance imaging (MRI) scans, as well as computed tomography (CT) scans. Tyropanoate sodium contains fatty acids, which are essential components of biological membranes. This drug has been shown to bind to the receptors of cancer cells in the prostate and pancreas, thereby inhibiting the growth of these cells. Tyropanoate sodium can also be used to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis. The drug is administered by injection or intravenously and binds to proteins in tissues, forming a polymeric matrix that may be excreted from the body via bile. Tyropanoate sodium also inhibits tumor growth in cervical cancer cells, with no adverse effects on healthy cells.

<p>Enalaprilat tert-butyl ester is a synthetic compound and impurity standard used in the synthesis of drug product. Enalaprilat tert-butyl ester is also a metabolite of enalapril, an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension, congestive heart failure, and diabetic nephropathy. Enalaprilat tert-butyl ester has been shown to have pharmacological effects similar to those of enalapril.</p>

<p>5-Oxo pitavastatin is a research and development drug product that is synthesized by custom synthesis. It is an impurity standard that is used as a reference in the analysis of pharmaceuticals and metabolites. The purity of this compound is over 99% with no detectable heavy metals, solvents, or other impurities. This product can be found in the pharmacopoeia, which lists it as an analytical reagent. 5-Oxo pitavastatin is used to develop drugs for niche markets and can be used to study metabolism.</p>

<p>Please enquire for more information about 1-[(4-Chlorophenyl)phenylmethyl]-4-(phenylsulfonyl)piperazine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>Remdesivir related compound 9 is a drug product that is an analytical standard. It is a natural API impurity, which has been synthesized for use as an impurity standard. This compound has been custom synthesized to be used as a research and development chemical. CAS No. 1439900-56-7 is the number of this synthetic drug product. It can be used in HPLC standards and it meets pharmacopoeia requirements for purity. The niche market for this compound is high purity analytical standards, including HPLC standards.</p>

<p>rac-Des(isopropylamino) acebutolol diol is a synthetic drug substance that is used for research and development purposes. It has a purity of 99% or greater, does not contain any impurities, and is manufactured using the latest technology. The rac-Des(isopropylamino) acebutolol diol is a pharmaceutical grade product with high purity and quality standards that have been verified by HPLC analysis. This compound is an analytical standard that can be used to calibrate mass spectrometry instruments. Rac-Des(isopropylamino) acebutolol diol is also metabolized into the natural metabolite noracebutanol by cytochrome P450 enzymes in humans.</p>

<p>6-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, racemic is a drug product that is used as an analytical standard in the development of new drugs. It is also used to study the metabolism of drugs. 6BPDC has been shown to inhibit bacterial growth by binding to DNA and RNA, thereby preventing transcription and replication. This metabolite can be synthesized in the laboratory.</p>

<p>Sulfo-Cy 3 carboxylic acid is a synthetic fluorescent dye that emits green light and has a fluorescence quantum yield of 0.7. It is prepared via the reaction of benzindole with 4-sulfonyl chloride in the presence of triethylamine and recrystallization from ethyl acetate. The emission wavelength can be tuned by varying the substituents on the indole ring, and it is stable with water solubility.</p>

<p>2- (Diethylboryl)pyridine is a custom synthesis drug product that is used in research and development for the treatment of cancer. 2- (Diethylboryl)pyridine has been shown to be active against various types of cancer cells, including leukemia, breast, prostate, ovarian, gastric and pancreatic cancers. This compound can also be used as an impurity standard for HPLC analysis.</p>

<p>Please enquire for more information about Thromboxane A2 potassium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Medoxomil is a magnetic resonance imaging contrast agent that belongs to the class of organic compounds called tetrazoles. Medoxomil is a white crystalline solid which has a melting point of about 200 degrees Celsius. It has been used as a pharmaceutical intermediate and in the process development of other drugs, such as impurities. Medoxomil is not soluble in water, but can be dissolved in solvents such as acetone or chloroform. The nitrogen atom in this molecule is protonated at physiological pH and interacts with an electron-rich aromatic ring, which leads to its magnetic properties. This compound's X-ray diffraction pattern shows it has a single crystal lattice structure with a space group P2(1). The 1H NMR spectrum indicates that it contains methyl derivatives, while the 13C NMR spectrum reveals that it also contains carbonyl and hydroxyl groups.</p>

<p>Clopidogrel Impurity A is a medicine that is used for the prevention of heart attacks, strokes, and blood clots in people with an increased risk of these events. It is not intended to be used for immediate relief from sudden symptoms. Clopidogrel Impurity A is a substance that may be found in some preparations of clopidogrel. The presence of this substance can be detected by liquid chromatography-mass spectrometry (LC-MS/MS) methods. The structural analysis of this substance was determined using enantiomeric resolution and chromatographic methods. This impurity has been shown to have no effect on the bioavailability of the parent drug, clopidogrel, when given orally to Sprague-Dawley rats.</p>

Valacyclovir Related Compound D is a synthetic metabolite of Valacyclovir. It is the primary metabolite of Valacyclovir, which has been shown to inhibit the activity of bacterial DNA polymerase. Valacyclovir Related Compound D is an impurity standard for valacyclovir and can be synthesized in quantities as per customer requirement.

Please enquire for more information about 3-Bromo-N-desethyl-N-benzyl lidocaine including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>4-(2-Hydroxy-3-isopropylaminopropoxy)benzoic acid 2-hydroxyethyl ester is a synthetic drug product that can be used as an HPLC standard. It has been shown to be metabolized in the rat, with the major metabolites being 2-hydroxyethoxyacetic acid and 4-(2-hydroxyethoxy)benzoic acid. This compound is not found naturally in any living organisms and is not an impurity of any API. The purity of this compound is &gt;98%.</p>

<p>2,2',3,3'-Tetrachlorobiphenyl is an inhibitor that has been shown to have anticancer properties. It inhibits the growth of tumor cells by blocking the activity of protein kinases, which are enzymes that regulate cell division and proliferation. This compound has been tested in Chinese hamster ovary cells and has been found to induce apoptosis in cancer cells. Additionally, 2,2',3,3'-Tetrachlorobiphenyl has analog inhibitors that have been tested in human urine samples and have shown potential as anticancer agents. These analogs inhibit cyclin-dependent kinases (CDKs), which play a crucial role in regulating the cell cycle. The inhibition of CDKs leads to the suppression of cancer cell growth and division, making this compound a promising candidate for future cancer treatments.</p>

<p>(E)-4-Alloxycarboxyl tamoxifen is a synthetic metabolite of tamoxifen. It is an impurity in the drug product, and can be found in the urine and blood of patients who have taken tamoxifen. The stability of (E)-4-Alloxycarboxyl tamoxifen has been studied by incubating it with rat liver microsomes at 37°C for 30 minutes. Metabolism studies have been done on rats and mice to measure the effect of (E)-4-Alloxycarboxyl tamoxifen on their endogenous levels of estrogen. The pharmacopoeia lists (E)-4-Alloxycarboxyl tamoxifen as a standard for HPLC analysis.</p>

<p>Polyethylene glycol monoisotridecyl ether (PEG-DTAE) is a polymer that can be used as an antimicrobial agent. It is active against Gram-positive bacteria but not against Gram-negative bacteria. PEG-DTAE has anti-angiogenic effects, which may be due to its ability to inhibit the growth of new blood vessels and thereby prevent the spread of infection. In vitro assays have shown that PEG-DTAE can induce cell lysis and hemolysis in test samples. PEG-DTAE has been shown to have hemolytic activity in vivo in rats, with histology sections showing inflammation and necrosis in the spleen and liver. This polymer also causes symptoms such as fever, chills, rigors, and hypotension in patients with chronic renal failure who are undergoing dialysis.</p>

<p>Epinephrine sulfonic acid-d3 is a synthetic, high purity, pharmacopoeia, drug development, analytical standard. It is used as an impurity standard, and in the synthesis of epinephrine sulfone. Epinephrine sulfonic acid-d3 has been shown to be a metabolite of epinephrine and its metabolites. This product has been synthesized and characterized by HPLC analysis using an ion-pairing agent and a gradient elution with water:acetonitrile (0.1% formic acid) (75:25).</p>

<p>Please enquire for more information about Daunorubicin EP impurity B including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Deshydroxypentanyl Posaconazole is a synthetic compound with an analytical standard available. It is a niche API that is not currently in use as a drug product. It is also an impurity standard for the HPLC and GC-MS analysis of deshydroxyphenyl fentanyl. Deshydroxypentanyl Posaconazole has been synthesized using the chemical reaction between desoxyphenyl fentanyl and posaconazole, which yields the desired product. The chemical structure of Deshydroxypentanyl Posaconazole can be found in CAS No. 161532-56-5.</p>

<p>N-Desmethyl sorafenib (pyridine)-N-oxide is a drug product that can be used as an HPLC standard and is also used in the development of drugs. CAS No. 583840-04-4 is a metabolite impurity that can be found in the analytical API impurity of the drug. This synthetic compound is subject to metabolism studies, which are conducted on animals for pharmacopoeia purposes. N-Desmethyl sorafenib (pyridine)-N-oxide has shown niche applications in the field of research and development, as it can be used as an analytical standard for HPLC.</p>

<p>Naltrexone Impurity G is a synthetic impurity found in naltrexone. It is used as an impurity standard and can be custom synthesized to meet the needs of researchers, developers, and manufacturers of drug products. Naltrexone Impurity G is a metabolite that has been shown to have pharmacological effects similar to those of naltrexone. It is used in metabolism studies. Naltrexone Impurity G has a purity level of 99% or higher and can be ordered as a methanol solution or powder.</p>

Sm21 is a 5-HT1A receptor antagonist that can be used to treat symptoms of Parkinson's disease. It binds to the 5-HT1A receptor and prevents the release of proinflammatory cytokines, such as tumor necrosis factor-α (TNF-α). Sm21 has also been shown to have antinociceptive effects in animals by acting as a 5-HT1A agonist. This drug can also be used for treatment of neuropathic pain because it inhibits the release of serotonin from nerve endings. The drug may exacerbate dyskinesia and cause neuropathic pain when it is used with dopamine antagonists.

Methisosildenafil is a chemical compound that belongs to the group of phosphodiesterase type-5 inhibitors. It is an analog of sildenafil and is used for the treatment of erectile dysfunction (ED). Methisosildenafil has been shown to be effective in animal models of pulmonary hypertension. It also inhibits the production of myeloid-derived suppressor cells, which are responsible for suppressing the immune system. Methisosildenafil has been found to be safe and well-tolerated for use as a pharmaceutical preparation in humans.

<p>Tert-butyl β-carboline-3-carboxylate is a GABAergic drug that binds to the benzodiazepine receptor and has been shown to be a nonselective antagonist. The drug has a high affinity for the benzodiazepine receptor, but does not bind selectively to any subunit of the receptor. Tert-butyl β-carboline-3-carboxylate is used in animal models to study depression and anxiety. It increases the release of gamma aminobutyric acid (GABA) in the ventral tegmental area and decreases locomotor activity in wild type mice, but has no effect on these behaviors in mice with a mutation in GABA receptors. In addition, this drug binds competitively to triazolam and blocks its binding site on GABA receptors. Tert-butyl β-carboline-3-carboxylate also inhibits ethanol consumption by wild type mice, but not by mutant mice lacking the</p>

Remdesivir impurity 1 is a drug product, analytical and Metabolism studies. It is a custom synthesis, Impurity standard, Synthetic and Drug development. Remdesivir impurity 1 is an API impurity that is a natural and has CAS No. 1355049-95-4. The HPLC standard of Remdesivir impurity 1 is high purity and pharmacopoeia.

<p>Raloxifene dimesylate hydrochloride is a drug product that is a synthetic estrogen. It has been used for the treatment of osteoporosis in postmenopausal women and to prevent or reduce the risk of invasive breast cancer in postmenopausal women at high risk of breast cancer. Raloxifene dimesylate hydrochloride is an impurity standard for HPLC. It is also used in research and development to study the effects of drugs on natural estrogen receptors, as well as to study their pharmacokinetics and metabolism in animals. Raloxifene dimesylate hydrochloride is a synthetic compound that can be custom synthesized. The drug product has been shown to have high purity with no API impurities. This compound has been approved by FDA and EPAR (European Medicines Agency) for use in humans.</p>

<p>Tetrahydro erlotinib is a drug product that is used in the treatment of non-small cell lung cancer. Tetrahydro erlotinib is an inhibitor of tyrosine kinases and can act on epidermal growth factor receptors, vascular endothelial growth factor receptors, and platelet-derived growth factor receptors. It has been shown to inhibit the proliferation of tumor cells in vitro and in vivo. Tetrahydro erlotinib is metabolized by CYP3A4 to form two major metabolites, which have similar pharmacological properties as the parent compound. These metabolites are eliminated from the body primarily through urinary excretion. Tetrahydro erlotinib may be toxic to the liver and kidneys due to its ability to induce hepatotoxicity and nephrotoxicity.</p>

<p>Please enquire for more information about Benzyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 8-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-octen-4-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-(Dibenzylamino)-3',4'-dihydroxy-acetophenone is a drug product that is used as an analytical reference standard for the metabolism studies of acetaminophen. It is also used in the development and production of drugs, including acetaminophen, which are metabolized by the liver. 2-(Dibenzylamino)-3',4'-dihydroxy-acetophenone is a white crystalline solid with a melting point of about 220°C. It has been shown to be a metabolite of acetaminophen and it can be synthesized from 2-aminoacetophenone and benzoic acid.</p>

<p>Desloratadine N-carboxylic acid methyl ester is an impurity in the drug product, Desloratadine. The chemical name for this impurity is desloratadine N-carboxylic acid methyl ester. This product can be found in the Metabolism studies section of our catalog under natural products. Desloratadine N-carboxylic acid methyl ester is a custom synthesis with a purity level of 99%. It is used as an analytical standard and has been shown to have similar retention times as the CAS No. 165740-03-4 reference standard.</p>

<p>Triacontanol is a medicinal compound that has been shown to have inhibitory activity against cancer cells, particularly breast cancer. It works by inhibiting the activity of kinases, which are enzymes that play a role in cell proliferation and mutation. Triacontanol has also been shown to have antibacterial activity, making it a potential candidate for the development of new antibiotics. In addition to its anti-cancer and antibacterial properties, triacontanol has been found to have protein kinase inhibitor activity in human cells. This makes it an attractive candidate for the development of novel therapeutic agents for a range of diseases.</p>

<p>Paliperidone E-oxime is used as a reference standard to calibrate impurities in drug products, and as an analytical reference standard. Paliperidone E-oxime is also used in the synthesis of other drugs. Paliperidone E-oxime has a CAS number of 1388021-46-2 and a molecular weight of 395.37 g/mol.</p>

<p>Benzenesulfonamide is a drug product that is used as an analytical standard. It is a synthetic drug that has been shown to be metabolized by the liver, forming metabolites such as hydroxybenzenesulfonamide and sulfamethoxazole. Benzenesulfonamide is not under any pharmacopoeia guidelines or regulations. The CAS number for this drug product is 20778-16-9.</p>

<p>Please enquire for more information about Benz[A]anthracene-7-acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ethyl 3-(3-amino-4-(2-((4-cyanophenyl)amino)-N-methylacetamido)-N-(pyridin-2-yl)benzamido)propanoate is an analytical standard and a drug development impurity in the preparation of HPLC standards. It is a metabolite that can be used as an impurity standard for the determination of purity by HPLC, and it is also available as a custom synthesis product. This compound has been assigned CAS No. 1648817-93-9.</p>

9,10-Dihydro-9,10-ethanoanthracene-9-carboxylic acid (DECA) is a halogenated aliphatic carboxylic acid that can be used as an oxidizing agent. It is a diluent in the synthesis of other compounds and can also act as a catalyst for reactions involving carboxylic acids. DECA has been shown to selectively oxidize carboxylic acids with one or more carbon atoms in the aliphatic chain. This is often done with propionic acid, which is oxidized to acrylic acid. The selectivity of DECA for this reaction is attributed to its ability to react with the carbonyl group in the carbon chain due to its electron withdrawing properties.

<p>Profluazol is an inhibitor of protein kinases that has shown potential in the treatment of cancer. This Chinese indole derivative has been found to inhibit the proliferation of leukemia cells and induce apoptosis in tumor cell lines. Profluazol specifically targets kinases involved in the regulation of cell cycle progression, such as cyclin-dependent kinase 2 (CDK2) and mitogen-activated protein kinase (MAPK), leading to a decrease in cancer cell growth. In addition, this compound has shown selectivity towards human cancer cells while sparing normal cells, making it a promising anti-cancer agent with minimal side effects.</p>

<p>N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)-benz eneacetamide is a drug product that is used in the development of new drugs. It is an analytical standard for HPLC and was created as a natural metabolite from the antibiotic Cefazolin. N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4 -fluoro -N-(3 -pyridinylmethyl) - 3 (trifluoromethyl) - benzeneacetic acid has been shown to inhibit</p>

N-Boc-N-desethyl acetildenafil is a synthetic drug product that is used as an analytical standard in metabolite studies. It is also used as an impurity standard for the synthesis of Acetildenafil, which is a drug used to treat erectile dysfunction. N-Boc-N-desethyl acetildenafil has a purity of 99% and can be synthesized in quantities ranging from 1 gram to kilograms. This product's CAS number is 1246820-46-1.br> br> N-Boc-N-desethyl acetildenafil has not been evaluated by the FDA and is not intended for human or veterinary use.

<p>L-Isoleucine orlistat is a drug product that is an analytical standard and a natural product. It is used in research and development for the study of drug metabolism, and as an impurity standard for synthetic L-isoleucine. L-Isoleucine orlistat has CAS number 1072902-75-0 and Impurity Standard Number (ISN) 910.<br>L-Isoleucine orlistat is not a registered active pharmaceutical ingredient (API). It can be custom synthesized to meet the requirements of a particular application, such as high purity, pharmacopoeia grade, or USP HPLC grade.</p>

2-(Propylamino)-propiotoluidid-hydrochlorid is a drug product that is used as an analytical standard for the determination of impurities in pharmaceuticals. It is a synthetic, natural, and research and development metabolite with niche applications. This product has been shown to be pharmacologically active in metabolism studies on animals. CAS No. 35891-99-7

<p>Deschloro amlodipine is a drug that is used for the treatment of high blood pressure. It belongs to a group of drugs called calcium channel blockers. Amlodipine has been shown to bind to and inhibit the activity of voltage-gated calcium channels in heart muscle, thereby lowering blood pressure. Deschloro amlodipine is an impurity standard for pharmacopoeia and analytical laboratories. The synthesis of deschloro amlodipine can be customized according to customer requirements. This product will be shipped as soon as possible after purchase.br&gt; br&gt; Desloro amlodipine is metabolized by cytochrome P450 enzymes, including CYP3A4, CYP2C9, and CYP2D6, which are found in the liver and intestines. These enzymes convert desloro amlodipine into two metabolites: 4-hydroxyamlodipine and 4</p>

<p>(2S,4R)-Fosinopril sodium salt is a prodrug that is converted to the active form fosinopril in the body. It is used to treat high blood pressure and heart failure. Fosinopril inhibits angiotensin-converting enzyme (ACE) and blocks the conversion of angiotensin I to angiotensin II. This leads to an increase in the production of a vasodilator called nitric oxide, which relaxes and widens blood vessels. Fosinopril also has been shown to have adverse effects on liver function, including increased liver enzymes and liver damage, as well as drug interactions with other nonsteroidal anti-inflammatory drugs (NSAIDs).</p>

<p>Please enquire for more information about 11-Oxo-betamethasone-17-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Propranolol hydrochloride is a non-selective beta-adrenergic blocker that blocks the effects of epinephrine, norepinephrine and dopamine. Propranolol hydrochloride has been shown to inhibit the activity of proximal tubules in the kidney, which may be due to its inhibition of chemical ionization. This drug also has antihypertensive activity and can be used for the treatment of cardiac disorders such as hypertension. Propranolol hydrochloride is a monoclonal antibody that is activated by nitro groups and binds with high affinity to multiple-reaction monitoring (MRM) transitions for protonated molecular ions at m/z 289, 296, 305, 313, 320, 328, 336 and 344. Propranolol hydrochloride also has vasodilatory effects on the papillary muscle which aids in regulating blood pressure by maintaining vascular resistance.</p>

<p>Maropitant citrate is a drug that has been shown to have clinical relevance in the treatment of chronic cough. It is a neurokinin-1 receptor antagonist that binds to the NK-1 receptor and blocks the effects of substance P. Maropitant citrate is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The terminal half-life of maropitant citrate is approximately 14 hours. The drug has low bioavailability due to its poor water solubility and high lipid solubility. This may be because it has a long fatty acid side chain that prevents its lipophilic properties from being fully utilized.</p>

<p>Damulin B is a potent inhibitor of cancer cell growth and proliferation. This protein analog has been shown to induce apoptosis, or programmed cell death, in Chinese hamster ovary (CHO) cells and other cancer cell lines. Damulin B is a promising medicinal compound for the treatment of leukemia and other types of cancer. It works by inhibiting kinase activity, which is essential for tumor growth and survival. Damulin B has also been found in human urine, indicating that it may have potential as a non-invasive diagnostic tool for cancer detection. With its potent anti-cancer properties, Damulin B represents a promising avenue for the development of new cancer therapies.</p>

Sacubitril Impurity 19 is a drug product that is used as an analytical standard for the purity and concentration of sacubitril. It is also used as an impurity in API manufacture. Sacubitril Impurity 19 is a natural metabolite of sacubitril, which is synthesized from the chemical reaction between sacubitril and hydroxypropyl-beta-cyclodextrin. The impurity has been shown to be eliminated through metabolism studies in rats. Sacubitril Impurity 19 can be found at a concentration of up to 0.2% in commercial samples of sacubitril. It may be present at levels up to 10% in medicinal products containing sacubitril.

4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one is a drug that has been developed for the treatment of cancer. It is an impurity standard used in HPLC and GC analysis to quantify the concentration of drugs. This compound is a metabolite of the drug carboplatin and can be found in urine as well as other biological fluids. Metabolites are substances produced by metabolism (chemical reactions) in the body. 4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one can also be found naturally in plants such as ivy or wild parsnip.

Sitagliptin is an oral dipeptidyl peptidase-4 inhibitor that is used to treat type 2 diabetes. It binds to the active site of the enzyme and reversibly blocks the action of the enzyme, thereby inhibiting the breakdown of a number of important hormones such as glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide. Sitagliptin hydroxy amide impurity is an impurity in sitagliptin that inhibits oxidoreductases, enzymes that catalyze oxidation reactions. The enantiomeric purity of sitagliptin hydroxy amide impurity is unknown.

<p>Ibuprofen amide is a nonsteroidal anti-inflammatory drug that belongs to the class of amides. It is an analog of ibuprofen, which has a hydrochloride group in place of the carboxyl group. Ibuprofen amide inhibits the production of pro-inflammatory chemicals by blocking cyclooxygenase enzymes, which are responsible for synthesis of prostaglandins and thromboxanes. The kinetic profile of this compound was obtained using fluorescence spectroscopy. This analytical method also showed that ibuprofen amide hydrolyzes in acidic conditions, suggesting that it may be active against bacteria that are found in an acidic environment.</p>

3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-chloroethyl)-4-methyl-1,3-thiazol-3-ium is a drug product that belongs to the group of synthetic drugs. It is metabolized by the liver and has an oral bioavailability of 100%. 3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-chloroethyl)-4-methylthiazol 3 -ium is used in research and development for pharmacopoeia standard. This compound is an impurity in the synthesis of other compounds, such as quetiapine.

<p>Please enquire for more information about Gossypol-d2 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine hydrochloride is an impurity that can be found in some commercially available drugs. It is a metabolite of the drug N-(4-amino-6,7-dimethoxyquinazol-2-yl)propylenediamine and is used as a reference standard for HPLC analysis. This compound has been shown to have antiplatelet activities.</p>

<p>Olodaterol is a drug product that has been synthesized using natural and synthetic methods. It is an API impurity that is present in the CAS No. 869478-13-7, which is a custom synthesis of olanzapine. The impurity standard for olodaterol benzyl ether is available as a Synthetic High Purity HPLC Standard. The purity of this product has been tested by HPLC and found to be &gt; 98%. Olodaterol can be used to develop drugs for niche markets, such as research and development or pharmacopoeia.</p>

Please enquire for more information about (3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>3-((3R,4S)-3,4-Dimethylpiperidin-4-yl)phenol is a potent inhibitor of cancer cell growth and tumor development. It has been shown to induce apoptosis in human cancer cells by inhibiting kinase activity. This compound is an analog of quetiapine and has anticancer properties. 3-((3R,4S)-3,4-Dimethylpiperidin-4-yl)phenol also exhibits inhibitory effects on somatostatin receptors in Chinese hamster ovary cells. It has been found in urine samples and may have potential as a therapeutic agent for the treatment of cancer. The compound has shown promising results as a kinase inhibitor with potential applications in the development of novel anticancer drugs.</p>

4-Hydroxy omeprazole sulfone is an analytical reference material which is a white crystalline powder with a melting point of about 190°C. It has the chemical name 4-hydroxyomeprazole sulfone and the CAS number 1346600-70-1. This product can be custom synthesized for research and development purposes. It is also used as an impurity standard for HPLC analysis. The purity of this product ranges from 98% to 99%.

Amlodipine besilate impurity D oxalate salt is a pharmaceutical ingredient that is an impurity in Amlodipine besilate and is used as a diluent. It has been shown to have a particle size of less than 10 microns, which makes it suitable for use in tablets. This product is stable at room temperature and does not require refrigeration. It also contains excipients including silicon dioxide and magnesium stearate, which are added to reduce the rate of crystallization and aid flowability.

<p>Des(2-methylbutyryl) pravastatin is a synthetic allylic alcohol that is synthesized from the natural product, pravastatin. It has been shown to have carboxylic acid and carboxylic functional groups as well as two hydrogens on the allylic side of the molecule. In addition, des(2-methylbutyryl) pravastatin has two allylic alcohols with two hydrogens on the allylic side of the molecule. The synthesis of this compound is done by reacting 2-methylbutanoic acid with an allyl bromide in a reaction catalyzed by sodium methoxide. This reaction produces a mixture of products that includes des(2-methylbutyryl)pravastatin.</p>

<p>Secologanin acetal is a lonicerae japonicae schisandrae fruit extract that is used in traditional Chinese medicines. It has been shown to have anti-inflammatory, anti-tumor, and antiviral activities. Secologanin acetal inhibits the production of nitric oxide and pro-inflammatory cytokines in polymorphonuclear cells (PMNs) by inhibiting the activation of NF-κB. Structural formula:</p>

Azoxystrobin acid is a natural product that is used as an analytical reference material and as an impurity standard. Azoxystrobin acid is synthesized by the reaction of azoxystrobin with acetic anhydride in the presence of triethylamine. The pure compound is obtained by recrystallization from methanol-water. Azoxystrobin acid has been shown to inhibit the growth of bacteria and fungi, and can be used for the treatment of infections caused by these microorganisms. Azoxystrobin acid also inhibits protein synthesis by binding to bacterial ribosomes. It has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

<p>1,2,3,4,5-Pentabromo-6-(2,3,4-tribromophenoxy)benzene is a medicinal compound that has been used in Chinese traditional medicine as an anticancer agent. It is an analog of a natural product found in urine that inhibits kinases involved in cancer cell growth and survival. This compound has been shown to induce apoptosis (programmed cell death) in tumor cells and inhibit the activity of proteins involved in cancer development. It acts as a potent inhibitor of kinase inhibitors and has demonstrated efficacy against various types of human cancers. Its unique molecular structure makes it an attractive candidate for further development as a potential therapeutic agent for cancer treatment.</p>

<p>Benzyl trisulfide is a compound that irreversibly inhibits enzyme activity, specifically protein kinase C. It has been shown to inhibit the proliferation of cancer cells and decrease the nuclear factor kappa-light-chain-enhancer (NF-κB) in squamous carcinoma cells. Benzyl trisulfide also has anti-inflammatory properties, as it can inhibit production of prostaglandin E2. This compound may be useful for prostate cancer treatment due to its effects on fatty acid metabolism.</p>

<p>Entecavir (1R,3R,4S) diastereomer is a synthetic compound and is an analytical standard for HPLC. This product is an impurity of the drug Entecavir. The impurity is characterized by a retention time of 17.8 minutes on HPLC and has been shown to be metabolized in vitro to 8-hydroxy-entecavir. The purity of this product is 98% with a CAS number of 1367369-78-5.</p>