APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.444 produits)
- Anthraquinones et Dérivés(407 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.465 produits)
- Dérivés des Benzodiazépines(335 produits)
- Glucides et Glycoconjugués(5.390 produits)
- Esters et Dérivés(42.308 produits)
- Acides Gras et Dérivés Lipidiques(32.489 produits)
- Flavonoïdes et Polyphénols(17.102 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(215 produits)
- Cétones et Dérivés(2.692 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.414 produits)
- Nitriles et Dérivés Cyano(3.070 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.494 produits)
- Phosphates et Phosphonates Organiques(1.205 produits)
- Sulfonates et Sulfates Organiques(10.452 produits)
- Composés Organométalliques(4.425 produits)
- Autres(6.340 produits)
- Peptides et Protéines(3.162 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.976 produits)
- Dérivés de Quinazoline et de Quinoléine(66.237 produits)
- Quinones et Dérivés(24.381 produits)
- Sels et Dérivés d’API(92.986 produits)
- Stéroïdes et Dérivés(4.987 produits)
- Sulfamides et Dérivés(2.607 produits)
- Terpénoïdes et Dérivés(3.871 produits)
- Thiazolidinediones et Thiopyranes(2.755 produits)
- Composés β-Adrénergiques(232 produits)
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66910 produits trouvés pour "APIs pour la recherche et les impuretés"
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Remdesivir impurity 6
CAS :Remdesivir impurity 6 is an impurity standard for a research and development drug product. It is a synthetic compound that has been custom synthesized for use in pharmacopoeia drug products. The purity of this compound is high and it has been shown to have no toxic effects on metabolism studies. Remdesivir impurity 6 is a metabolite of remdesivir, which is used as an antiviral agent for the treatment of HIV infection.Formule :C15H24NO5PDegré de pureté :Min. 95%Masse moléculaire :329.33 g/mol5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic
CAS :5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic is a drug product that is used for the research and development of drugs. It is manufactured synthetically. This compound has been shown to be metabolized in rats and humans. Studies have also shown that this compound may be an impurity in other drugs. The use of 5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic can be found in the USP/NF as a HPLC standard or as an analytical reference standard.Formule :C15H12BrO3NDegré de pureté :Min. 95%Masse moléculaire :334.16 g/mol(S)-2-Ethylbutyl 2-aminopropanoate hydrochloride
CAS :Remdesivir impurityFormule :C9H20ClNO2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :209.71 g/molLisinopril EP Impurity E
CAS :Lisinopril EP Impurity E is an impurity of lisinopril, which is a prescription drug used to treat high blood pressure. This impurity was found in a preparative high performance liquid chromatography (HPLC) and mass spectroscopy analysis of the drug. The molecular weight of Lisinopril EP Impurity E was determined to be 317.2 amu, which corresponds to the molecular formula C7H13NO2. The FT-IR spectrum showed that this impurity has an ammonium group at 1859 cm-1 and butanoic acid at 1647 cm-1.Formule :C21H31N3O5Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :405.49 g/molD-Ser(11)-Semaglutide
D-Ser(11)-Semaglutide is a semaglutide impurity. The amino acid at position 11 has been replaced by the D-form of the amino acid D-serine (D-Ser). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Formule :C187H291N45O59Masse moléculaire :4,113.64 g/molN-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroacetamide sodium salt
CAS :2-Nitroacetamide sodium salt is an impurity of the drug N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroacetamide, a synthetic chemotherapeutic agent for the treatment of cancers. This compound has been shown to have metabolism studies and natural properties. It has a CAS number of 112251-56-6 and is found in the pharmacopoeia. 2-Nitroacetamide sodium salt is a custom synthesis that can be used as a reference standard for HPLC analysis. It can also be used as a drug product or metabolite in drug development.
Formule :C12H18N3O4SNaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :323.34 g/mol4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine
CAS :4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine is an impurity standard of the drug product. It is a high purity synthetic compound with a niche in pharmacopoeia and drug development. 4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine has been shown to be a metabolite of the natural product.Formule :C6H5IN4Degré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :260.04 g/molPitavastatin 3S,5R isomer calcium
CAS :Pitavastatin 3S,5R isomer Calcium Salt is a potent inhibitor of cholesterol biosynthesis. It is marketed as the hemihydrate form under the trade name Pravacol and is used in the treatment of type 2 diabetes. Pitavastatin 3S,5R isomer Calcium Salt inhibits cholesterol biosynthesis by blocking HMG-CoA reductase, which converts 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) to mevalonate (MVA). The active metabolite, pitavastatin, binds to the regulatory region of HMG-CoA reductase and prevents it from converting MVA to HMG-CoA. This reduces the pool of HMG-CoA available for conversion to cholesterol. The inhibition of this enzyme slows down the production of cholesterol and decreases blood levels. It has been approved for use in adults with type 2 diabetes and for lowering highFormule :(C25H24FNO4)2•CaDegré de pureté :Min. 95%Couleur et forme :White/Off-White SolidMasse moléculaire :880.98 g/molDes(2-methylbutyryl) pavastatin sodium
CAS :Des(2-methylbutyryl)pavastatin sodium is a synthetic analog of the natural product, pravastatin. It is the methyl ester of the active metabolite of pravastatin and has been shown to be an effective inhibitor of cholesterol biosynthesis. Des(2-methylbutyryl)pavastatin sodium is used in drug development as an analytical standard and as a research and development impurity standard for HPLC. This compound's CAS number is 151061-28-8, making it a niche product that does not require extensive synthesis.
Formule :C18H29NaO6Degré de pureté :Min. 95%Masse moléculaire :364.41 g/mol{(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1.3-oxazolidin-5-yl}methyl acetate
CAS :This product is a metabolite of the drug product and impurity standard. It has been synthesized as a custom synthesis to meet the needs of research and development, pharmacopoeia, or natural products. This compound is an API impurity that has been characterized by HPLC. The purity of this product is high, with a minimum purity of 98%.Formule :C16H19FN2O5Degré de pureté :Min. 95%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :338.33 g/molAztreonam impurity D
CAS :Aztreonam impurity D is a metabolite of aztreonam. Aztreonam impurity D is an impurity standard for the pharmacopoeia and API industry, as well as for drug development and research. It has been shown that this compound inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Aztreonam impurity D also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.Formule :C13H17N5O5SDegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :355.37 g/mol(S)-Ethyl 2-ethoxy-4-[[[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]amino]carbonyl]methyl]benzoate
CAS :(S)-Ethyl 2-ethoxy-4-[[[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]amino]carbonyl]methyl]benzoate is an intermediate in the synthesis of repaglinide. It is a reagent that reacts with ethylamine and carbodiimide hydrochloride to form a urea derivative. This urea derivative is then reacted with filtration to give the desired product, which is recrystallized from dichloromethane solution. The (S)-ethyl 2-ethoxy-4-[(N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]amino)carbonyl]-methyl benzoate can be converted into the ester, phenylacetic acid, through hydrolytic reaction.Formule :C29H40N2O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :480.64 g/molRifaximin EP Impurity D
Rifaximin EP Impurity D is an analytical impurity that has been identified as a metabolite of the drug Rifaximin. It is a white crystalline powder with no characteristic odor. This product can be used as an HPLC standard, niche compound, or pharmacopoeia impurity. It can also be custom synthesized to meet the needs of your research and development project.
Degré de pureté :Min. 95%All-trans-retinol-d5
CAS :Produit contrôléAll-trans-retinol-d5 is a supplement that is used to protect the brain from oxidative damage and to help maintain healthy skin. It is an antioxidant that prevents free radicals from damaging cells and helps maintain the structural integrity of cell membranes. All-trans-retinol-d5 can be found in high concentrations in animal tissues, such as liver, lung, kidney, heart, brain, and eye. It can also be found in human urine. The presence of all-trans-retinol-d5 in urine has been correlated with neuroprotective effects. Retinol levels have been shown to be higher in children who are less obese than those who are obese or overweight. All-trans retinol has been shown to inhibit cancer cell proliferation and induce apoptosis by inhibiting protein synthesis at the level of transcription.
Formule :C20H25D5ODegré de pureté :(%) Min. 80%Couleur et forme :Clear Viscous LiquidMasse moléculaire :291.48 g/molMethyl 4-hydroxy-2-methyl-(2H)-1,2-benzothiazine-3-carboxylate-1,1-dioxide
CAS :Methyl 4-hydroxy-2-methyl-(2H)-1,2-benzothiazine-3-carboxylate-1,1-dioxide is a centrosymmetric molecule with an aspergillus flavus conformation. It is an acetanilide derivative that has been shown to be an effective antioxidant and medicine for the treatment of cancer. This product is also used in the production of hydrogen bonds and linkers in organic synthesis. The yields are high and it can be oriented during irradiation.Formule :C11H11NO5SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :269.28 g/mol(1R,4S)-N-Desmethyl sertraline hydrochloride
CAS :Sertraline metaboliteFormule :C16H16Cl3NDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :328.66 g/mol2,4-Dicyano-3-(3,4-dihydroxy-5-nitrophenyl)-N1,N1,N5,N5-tetraethylpentanediamide
2,4-Dicyano-3-(3,4-dihydroxy-5-nitrophenyl)-N1,N1,N5,N5-tetraethylpentanediamide is a white crystalline solid that is used as an analytical reference standard in HPLC. It is used for the determination of purity and impurities in pharmaceuticals and drug products. This compound can be custom synthesized or obtained from natural sources. It can be found in the USP Drug Impurity Standards and the European Pharmacopoeia.Formule :C21H27N5O6Degré de pureté :Min. 95%Masse moléculaire :445.47 g/molSemaglutide Impurity 29 (beta-Asp-9)
Beta-Asp-(9)-Semaglutide is a semaglutide impurity. The amino acid at position 9 has been replaced by the beta-aspartic acid (also known as isoaspartic, isoAsp, β-Asp or beta-Asp). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Formule :C187H291N45O59Masse moléculaire :4,113.64 g/mol3,5-Di-O-(4-chlorobenzoyl)-2-deoxy-a-D-ribofuranosyl isocyanate
3,5-Di-O-(4-chlorobenzoyl)-2-deoxy-a-D-ribofuranosyl isocyanate (CAS No. 53477) is a drug product that belongs to the class of drugs called nucleosides. 3,5-Di-O-(4-chlorobenzoyl)-2-deoxy-a-D-ribofuranosyl isocyanate has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. This product has been shown to have antiplasmodial activity and may be useful in the treatment of malaria.Formule :C20H15Cl2NO6Degré de pureté :Min. 95%Masse moléculaire :436.24 g/mol4-Desmethoxy omeprazole sulfide
CAS :4-Desmethoxy omeprazole sulfide is a metabolite of omeprazole, a drug that is used to treat ulcers and gastroesophageal reflux disease. 4-Desmethoxy omeprazole sulfide is not an impurity in the production of omeprazole, but is present as a natural component of omeprazole. This compound has been shown to be an impurity standard for HPLC analysis. The pharmacopoeia defines 4-desmethoxy omeprazole sulfide as an API impurity in drug products. It is also being studied for its potential use in drug development and research and development.
Formule :C16H17N3OSDegré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :299.39 g/mol
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