APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.444 produits)
- Anthraquinones et Dérivés(407 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.465 produits)
- Dérivés des Benzodiazépines(335 produits)
- Glucides et Glycoconjugués(5.390 produits)
- Esters et Dérivés(42.308 produits)
- Acides Gras et Dérivés Lipidiques(32.489 produits)
- Flavonoïdes et Polyphénols(17.102 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(215 produits)
- Cétones et Dérivés(2.692 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.414 produits)
- Nitriles et Dérivés Cyano(3.070 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.494 produits)
- Phosphates et Phosphonates Organiques(1.205 produits)
- Sulfonates et Sulfates Organiques(10.452 produits)
- Composés Organométalliques(4.425 produits)
- Autres(6.340 produits)
- Peptides et Protéines(3.163 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.976 produits)
- Dérivés de Quinazoline et de Quinoléine(66.237 produits)
- Quinones et Dérivés(24.381 produits)
- Sels et Dérivés d’API(92.986 produits)
- Stéroïdes et Dérivés(4.987 produits)
- Sulfamides et Dérivés(2.607 produits)
- Terpénoïdes et Dérivés(3.871 produits)
- Thiazolidinediones et Thiopyranes(2.755 produits)
- Composés β-Adrénergiques(232 produits)
Affichez 21 plus de sous-catégories
66910 produits trouvés pour "APIs pour la recherche et les impuretés"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Methyl 2-disazobenzoate hydrochloride
CAS :Methyl 2-disazobenzoate hydrochloride is a drug product that is used as an HPLC standard and as a metabolite in the development of drugs. It has been found to be naturally occurring and is a research and development metabolite. Methyl 2-disazobenzoate hydrochloride is also an impurity of API, which can be quantified in analytical studies. It is a synthetic compound with CAS No. 35358-78-2 and it can be used to manufacture high purity pharmaceuticals. Methyl 2-disazobenzoate hydrochloride has been shown to have niche pharmacological effects, such as anti-inflammatory activities.Formule :C8H7N2O2ClDegré de pureté :Min. 95%Masse moléculaire :198.61 g/molGliclazide impurity F
CAS :Gliclazide is a sulfonylurea drug that is used to treat type 2 diabetes. The impurity F, which is an impurity standard, can be synthesized by reacting 1-chloro-2,6-difluoroaniline with sodium methoxide in methanol. It is also an API impurity found in the synthesis of gliclazide and can be custom synthesized for research and development purposes. Gliclazide impurity F has a CAS number of 1076198-18-9 and the molecular formula C8H4ClF3NOS. This product has a purity of >99% and is classified as synthetic. It has been shown to have pharmacopoeia activity and can also be used for niche applications such as drug development.Formule :C15H21N3O3SDegré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :323.41 g/molPteroic acid - 60%
CAS :Pteroic acid is a synthetic compound that is an analog of the natural amino acid phenylalanine. It has been shown to inhibit protein synthesis and may be useful for the treatment of cancer. Pteroic acid can be activated by the addition of trifluoroacetic acid and reacts with metal ions such as nickel, cobalt, copper, and zinc. It also binds to receptors on tubule cells in kidney tissue. This binding inhibits the enzyme carbonic anhydrase II, which catalyzes the conversion of carbon dioxide to bicarbonate in these cells. The inhibition of this enzyme results in a decrease in bicarbonate concentration within these cells, leading to cell death.Formule :C14H12N6O3Degré de pureté :Min. 93 Area-%Couleur et forme :PowderMasse moléculaire :312.28 g/molTrandolaprilat
CAS :Trandolaprilat is a prodrug of enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilat binds to the active site of ACE and inhibits its activity, thereby causing a decrease in the formation of angiotensin II, a potent vasoconstrictor. Trandolaprilat has been shown to be effective in treating congestive heart failure and other cardiac disorders. Trandolaprilat has also been shown to have an effect on energy metabolism, as it inhibits the binding of ATPase to adenosine triphosphate (ATP). This inhibition leads to increased levels of ATP in cells and may be responsible for its cardioprotective effects.
Formule :C22H32N2O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :420.5 g/molAmiodarone N-oxide HCl
CAS :Amiodarone N-oxide HCl is a class III antiarrhythmic drug that acts by slowing the heart rate and prolonging the time between heartbeats. It has been shown to be effective in treating atrial fibrillation, ventricular fibrillation, and atrial flutter. Amiodarone N-oxide HCl has significant cytotoxicity, which can lead to cardiomyopathy and myocardial infarcts. Due to its long half life, amiodarone can accumulate in the body and cause side effects such as pulmonary toxicity, gastrointestinal bleeding, thyroid dysfunction, or liver damage. It is not recommended for use in patients with structural heart disease or those taking nonsteroidal anti-inflammatory drugs (NSAIDs) because of an increased risk of adverse events.Formule :C25H29I2NO4HClDegré de pureté :Min. 95%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :697.77 g/mol2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt
2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt is a white to off-white crystalline powder. It is soluble in water and sparingly soluble in alcohol. This product is used as an analytical standard and has been found to be a metabolite of the drug clozapine. 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt has also been found to be an impurity in the drug product lamotrigine.Formule :C24H29NO5•NaDegré de pureté :Min. 95%Masse moléculaire :434.49 g/mol(S)-N2-(Methoxymethyl)-N6-proply-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6 diamine)
(S)-N2-(Methoxymethyl)-N6-proply-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6 diamine) is an API impurity. CAS No. for this product is not available. This product is a custom synthesis and can be purchased as a research and development product. It has been shown to inhibit the activity of bacterial DNA gyrase and topoisomerase IV, which maintains the integrity of bacterial DNA. The chemical name for this product is (S)-N2-(Methoxymethyl)-N6-proply-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6 diamine).Formule :C12H23N3OSDegré de pureté :Min. 95%Masse moléculaire :257.4 g/mol1,3-Bis[(p-chlorobenzylidene)amino]guanidine hydrochloride
CAS :1,3-Bis(p-chlorobenzylidene)amino]guanidine hydrochloride (1,3-BCBGAH) is a method for the determination of p-hydroxybenzoic acid in reaction solutions. It is used as an analytical reagent in the analysis of p-hydroxybenzoic acid in pharmaceuticals and other organic chemicals. The matrix effect can be reduced by adding quillaja saponaria to the extraction solution. The main application of this compound is for the detection of resistant mutants in infectious diseases such as liver lesions and tissue infection. 1,3-BCBGAH has also been shown to be effective against robenidine and polymyxin B., with a more favorable toxicity profile than maduramicin ammonium or anhydrous sodium.Formule :C15H14Cl3N5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :370.66 g/molCiprofloxacin impurity A
CAS :Ciprofloxacin impurity A is an analog of ciprofloxacin and is a pharmaceutical preparation that belongs to the class of fluoroquinolones. It has been shown to be active against P. aeruginosa and other gram-negative bacteria in wastewater treatment systems. Ciprofloxacin impurity A is activated by ethylene diamine and can be eluted with acidic solvents. It also inhibits tumor cell line growth through adsorption mechanism and is used as a drug for cancer chemoprevention in combination with malic acid.Formule :C13H9ClFNO3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :281.67 g/molD-Ala-(19)-Semaglutide
D-Ala(19)-Semaglutide is a semaglutide impurity. The amino acid at position 19 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Formule :C187H291N45O59Masse moléculaire :4,113.64 g/molrac-2-Cyano-2-phenylbutanamide
CAS :Rac-2-cyano-2-phenylbutanamide is a synthetic molecule that is used as a growth regulator. It has been shown to be toxic to the arthropod Mollusca, with an LD50 of 1.6 µg/cm² (milligrams per square centimeter). Rac-2-cyano-2-phenylbutanamide also inhibits the growth of organisms such as Anisopliae and Metarhizium, and has been shown to have an asymmetric effect on tissue culture cells. Rac-2-cyano-2-phenylbutanamide is chemically related to the antibiotic subtilin, which belongs to the class of aminoglycoside antibiotics. Rac-2-cyano-2-phenylbutanamide may inhibit bacterial protein synthesis by binding to ribosomes and blocking the attachment of aminoacyl tRNA molecules during translation. This compound also inhibits DNA replication in bacteria by preventing DNAFormule :C11H12N2ODegré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :188.23 g/molN-Desmethyl cyamemazine maleate
CAS :Cyamemazine is an antipsychotic drug that has been used for the treatment of schizophrenia and other psychotic disorders. N-Desmethyl cyamemazine maleate, a metabolite of cyamemazine, has been shown to have neuroprotective effects in vitro.Formule :C18H19N3S·C4H4O4Degré de pureté :Min. 95%Masse moléculaire :425.5 g/molMolnupiravir Impurity 8
CAS :Produit contrôléMolnupiravir Impurity 8 is an impurity of molnupiravir, a drug product. It is a synthetic chemical compound that has not been found in nature. Molnupiravir Impurity 8 is the result of metabolism studies on the API (active pharmaceutical ingredient) and was observed to be more abundant than other impurities. Molnupiravir Impurity 8 is a white crystalline solid with CAS number 2492423-30-8. It is soluble in water, ethanol, acetone, and chloroform. The purity of this impurity is 99%.Formule :C13H19N3O7Degré de pureté :Min. 95%Masse moléculaire :329.31 g/molBiotin impurity C
CAS :Biotin impurity C is a metabolite that is found in drugs that contain biotin. It is an impurity standard for HPLC analysis, which can be used to identify and quantify the amount of biotin in a drug product. Biotin impurity C is also used as an analytical standard. This compound has been shown to have pharmacological properties, such as anti-inflammatory effects and immunomodulatory effects.Formule :C9H14N2O2SDegré de pureté :Min. 95%Masse moléculaire :214.28 g/mol5-Methyl Zolpidem
CAS :5-Methyl Zolpidem is a zolpidem tartrate that is used for the treatment of insomnia and as a sedative. It is an intermediate in the synthesis of zolpidem tartrate, which is synthesized from 5-methyl-1-(4-methoxybenzoyl)-1H-benzo[d]imidazole with potassium t-butoxide. The synthesis starts with the conversion of 5-methyl-1-(4-methoxybenzoyl)-1H-benzo[d]imidazole to 1-(4'-methylphenyl) benzene by reaction with methyl iodide followed by hydrolysis of the ester group to form 1-(4'-methylphenyl) benzene. The next step involves a nucleophilic substitution reaction using potassium t-butoxide to produce 1-(4'-methylphenyl) benzene t-butoxide, followed by reaction with methanolFormule :C19H21N3ODegré de pureté :Min. 95%Couleur et forme :White/Off-White SolidMasse moléculaire :307.39 g/molN-Despropyl ropinirole hydrochloride
CAS :N-Despropyl ropinirole hydrochloride is a synthetic drug product that is used as a research and development impurity standard. It is also used in the synthesis of other drugs and has been shown to have an analytical purity of 99%. N-Despropyl ropinirole hydrochloride is not active against bacteria, fungi, or viruses.Formule :C13H19ClN2ODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :254.75 g/molEthyl 3-aminopyrazole-4-carboxylate
CAS :Ethyl 3-aminopyrazole-4-carboxylate is an anticancer drug that inhibits the growth of cancer cells by inhibiting protein synthesis. It has been shown to inhibit the activity of dpp-iv and pde5, which are enzymes involved in cellular proliferation. Ethyl 3-aminopyrazole-4-carboxylate has also been shown to have antiinflammatory properties, which may be due to inhibition of prostaglandin synthesis.
Ethyl 3-aminopyrazole-4-carboxylate is a multinuclear compound that reacts with nitrogen atoms from the pyrazoles to form a stable molecule. Dimethylformamide is used as a solvent for this reaction. The synthesis of ethyl 3-aminopyrazole-4-carboxylate starts with acetylation, which converts the carboxylic acid group into an acetic acid group. The acetic acid group reacts with ammonia and hydrogen cyanFormule :C6H9N3O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :155.16 g/molN,N'''-(Dithia-2,1-ethanediyl)bis-(N'-cyano-N''-methyl)guanidine
CAS :N,N'''-(Dithia-2,1-ethanediyl)bis-(N'-cyano-N''-methyl)guanidine is a metabolite of guanidine. It is a synthetic compound that is used as an analytical reference standard and impurity in pharmaceutical products. It is also used to create an impurity standard for HPLC analysis. This compound has been found in natural sources such as plants and animal tissues, but it can also be synthesized in the lab. The CAS number for this substance is 74886-59-2.
Formule :C10H18N8S2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :314.43 g/molCefpodoxime proxetil impurity H
CAS :Cefpodoxime proxetil impurity H is an impurity of cefpodoxime proxetil, which is a prodrug that has been shown to be metabolized by esterases to the active form cefpodoxime. Cefpodoxime proxetil impurity H was found in the elution fraction when using liquid chromatography with reversed-phase as the separation method. It is thought that this impurity may arise from the use of methanol in the process of preparing cefpodoxime proxetil, although other mechanisms have not been ruled out. The mass spectrum for cefpodoxime proxetil impurity H shows peaks at m/z 812 and 682, which correspond to the parent drug and its hydrolysis product, respectively. The fragmentation pattern observed for cefpodoxime proxetil impurity H corresponds to that seen for cephalosporins.Formule :C42H54N10O18S4Degré de pureté :Min. 95%Masse moléculaire :1,115.2 g/mol
![1,3-Bis[(p-chlorobenzylidene)amino]guanidine hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIB57827.webp&w=3840&q=75)
