APIs pour la recherche et les impuretés

Nabumetone is a nonsteroidal anti-inflammatory drug that is metabolized by the liver to form a dimer. The major metabolite of nabumetone is the dimer, which has been used as an impurity standard for this drug. Nabumetone has been shown to inhibit prostaglandin synthesis, and its metabolites have been studied for their effects on various enzymes.

Micafungin Metabolite M1 is a metabolite of Micafungin. It is an impurity in the drug product and is not active. Micafungin Metabolite M1 has been proposed as a pharmacopoeia reference standard for HPLC quantification of Micafungin.

Trap 101 is a potent anticancer agent that is derived from xylose. This compound has been shown to induce apoptosis in cancer cells by inhibiting kinases, which are enzymes that play a key role in tumor growth and progression. Trap 101 specifically targets Chinese hamster ovary cells and human cancer cell lines, making it a promising candidate for the treatment of various cancers. In addition, Trap 101 acts as a kinase inhibitor and has been shown to be effective against several types of tumors. This compound can be detected in urine samples, making it an attractive candidate for non-invasive diagnostic tests for cancer patients. Overall, Trap 101 holds great potential as a novel therapeutic agent for cancer treatment.

Please enquire for more information about Mangostin-d3 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Ethylene terephthalate cyclic hexamer-d24 is a synthetic drug product. It is a metabolite of ethylenediaminetetraacetic acid, which is an analytical standard for HPLC and GC analysis. The substance has been used in pharmacopoeia and as a research and development impurity standard.

Tovinontrine is a potent Chinese anticancer drug that targets the kinase pathway in cancer cells. It has been shown to inhibit cell cycle progression and induce apoptosis in cancer cells, making it a promising candidate for cancer treatment. Tovinontrine also has protein kinase inhibitory activity and can be used as an inhibitor of tumor growth. This drug is highly effective against various types of human cancers, including breast, lung, prostate, and colon cancer. Additionally, Tovinontrine has been shown to have synergistic effects with other anticancer drugs such as betamethasone and vitamin D3. The urine concentration of Tovinontrine can be used as a biomarker for the diagnosis and monitoring of cancer patients undergoing treatment with this drug.

N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-1-naphthalenemethanamine (DHEA) is a human metabolite and an endogenous hormone. DHEA has been shown to have antifungal activity against Candida albicans in vitro. It also possesses an inhibitory effect on the growth of some fungi that are resistant to azole drugs, such as Coccidioides immitis, Cryptococcus neoformans and Blastomyces dermatitidis. DHEA has been used in the treatment of pediatric patients with chronic granulomatous disease and is currently being evaluated for use in other pediatric conditions.

Please enquire for more information about 3’,4’-Bis(hydroxyethyl)rutoside including the price, delivery time and more detailed product information at the technical inquiry form on this page

Threo ifenprodil hemitartrate is a drug product that has been synthesized and analyzed. It is an impurity standard for the synthesis of ifenprodil HCl. The purity of this product is greater than 99% and meets the requirements of the USP-NF, EP, BP, JP, and the pharmacopoeias of other countries. This product can be used in drug development research and development to develop drugs for niche markets.

D-Threo-3,4-dihydroxyphenylserine hydrochloride is a potent inhibitor that has been shown to induce apoptosis in various cancer cell lines. It works by inhibiting kinases and proteins involved in the cell cycle, resulting in the inhibition of tumor growth. This compound has been extensively studied for its anticancer properties and has shown promising results in human clinical trials. D-Threo-3,4-dihydroxyphenylserine hydrochloride is derived from Chinese medicinal herbs and can be isolated from urine or synthesized chemically. Its ability to selectively inhibit cancer cell growth makes it a potential candidate for future cancer therapies.

AC-263093 is a medicinal compound that acts as an inhibitor of apoptosis, which is the natural process of programmed cell death. It has been shown to be effective in inhibiting tumor growth by targeting specific kinases and proteins involved in the cell cycle. AC-263093 works by blocking the activity of certain kinases, which are enzymes that regulate various cellular processes. This inhibition leads to the disruption of cancer cell growth and division, ultimately resulting in cell death. This compound has demonstrated anticancer properties and has been tested on various human cancer cell lines with positive results. Its potential as an effective treatment for cancer makes it a promising candidate for further research and development.

10-Oxo-trans-8-decenoic acid is a potent inhibitor that has been found to have anticancer properties. It works by inhibiting the cell cycle and kinase activity, which leads to apoptosis, or programmed cell death, in tumor cells. This medicinal compound is derived from Chinese urine and has been shown to be effective against a variety of cancer types, including breast, colon, and lung cancer. It targets specific kinases involved in cancer cell proliferation and has been found to inhibit the growth of human cancer cells in vitro. 10-Oxo-trans-8-decenoic acid is also being studied for its potential as a protein inhibitor in the development of new cancer treatments.

PZ-II-029 is an analog of a Chinese medicinal compound that has shown promising results in the treatment of cancer. This compound has been found to induce apoptosis (programmed cell death) and arrest the cell cycle in human cancer cells. PZ-II-029 is an inhibitor of a protein kinase, which plays a critical role in the growth and proliferation of tumor cells. This potent anticancer agent has been shown to be effective against various types of tumors and may have potential for use in combination with other cancer treatments. PZ-II-029 is derived from urine and is part of a new class of kinase inhibitors that hold great promise for the future of cancer therapy.

Dec-poc pmpa is an oral prodrug that exhibits potent antiviral activity against HIV. It is rapidly converted to its active form, tenofovir alafenamide hemifumarate, in the presence of hydrochloric acid. Dec-poc pmpa has excellent pharmacokinetic properties, resulting in sustained plasma levels and enhanced bioavailability compared to other pharmaceutical preparations of tenofovir. This prodrug undergoes a phase transfer reaction in the body, allowing for efficient conversion to the active antiretroviral agent. Additionally, Dec-poc pmpa has been formulated to minimize impurities and contains an acid-binding agent to reduce potential renal biomarkers associated with tenofovir administration. Its mechanism of action involves inhibiting viral replication by targeting adenine residues in viral DNA synthesis.

Cefmetazole diphenylmethyl ester is an analog of the antibiotic cefmetazole that has shown promising anticancer activity. It has been found to induce apoptosis in human cancer cells and inhibit the activity of various kinases, which are involved in the regulation of cell cycle and proliferation. Cefmetazole diphenylmethyl ester acts as a potent inhibitor of protein kinases, making it a promising candidate for the development of new medicinal drugs for cancer treatment. This compound has also been found to be excreted in urine, suggesting its potential use as a diagnostic tool for detecting tumors. Overall, cefmetazole diphenylmethyl ester shows great potential as an effective inhibitor of cancer cell growth and proliferation.

Please enquire for more information about (E)-3-{6-(4-Toluoyl-2-pyridyl}-acrylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Suspensolide is a medicinal compound that has been shown to have potent anticancer properties. It is an analog of a protein found in Chinese medicine and acts as a kinase inhibitor, blocking the activity of enzymes involved in cancer cell growth and proliferation. Suspensolide induces apoptosis, or programmed cell death, in human cancer cells and has shown promising results as a potential treatment for various types of tumors. This compound can be detected in urine samples and has the potential to become an important tool in cancer therapy.

(2R,3R,11Br)-rel-9-deme-dtbz is an analog of tolvaptan that has potent anticancer properties. It acts as a kinase inhibitor and induces apoptosis in cancer cells. This compound has been shown to inhibit the activity of several kinases, including protein kinase B (AKT), mitogen-activated protein kinase (MAPK), and extracellular signal-regulated kinase (ERK). It also inhibits the growth of human tumor xenografts in Chinese hamsters. Additionally, (2R,3R,11Br)-rel-9-deme-dtbz has been found to be a promising candidate for the treatment of cancer due to its high selectivity towards cancer cells and low toxicity towards normal cells. Its potent anticancer activity makes it a valuable tool for cancer research and drug development.

Diamidafos is a potent anticancer drug that has been used in Chinese traditional medicine to treat tumors. It acts as a protein kinase inhibitor, preventing the phosphorylation of proteins involved in cell growth and survival. Diamidafos is an analog of staurosporine, one of the first protein kinase inhibitors discovered. It has been shown to induce apoptosis in cancer cells by inhibiting the activity of various kinases. Diamidafos has also been found to inhibit the growth of human cancer cells and reduce tumor size in animal models. In addition, it can be administered orally and is excreted primarily through urine. To improve its efficacy, diamidafos can be combined with chitosan, a natural polymer that enhances drug delivery and bioavailability.