Composés et métabolites pharmaceutiques et vétérinaires

<p>Xanthine, a purine breakdown product, is turned into uric acid by xanthine oxidase and blocks adenosine receptors.</p>

<p>(±)-1,2-Propanediol (Methyl ethyl glycol) is an aliphatic alcohol that is frequently used as an excipient to improve solubility and stability of drugs.</p>

<p>D-Glucose-13C6 (Dextrose-13C6), a C13 marker, serves as a metabolic tracer and can be used to study metabolism-related diseases in the body.</p>

<p>4-Vinylphenol, a metabolite from lactic acid bacteria in wine, induces apoptosis. Found in Hedyotis diffusa Willd.</p>

<p>Applications (S)​-​(-​)​-​1,​2,​4-​Butanetriol is a general reagent used in organic synthesis. Used in the enantioselective preparation of a cyclobutane analogue of Milnacipran.<br>References Nguyen, D. et al.: Org. Chem. Front., 4, 1276 (2017);<br></p>

<p>Theobromine (3,7-Dimethylxanthine), a xanthine alkaloid, is used as a bronchodilator and as a vasodilator.</p>

<p>Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.</p>

<p>Estrone sulfate sodium, an inactive estrogen ester, transforms into estrone via steroid sulfatase. It's studied for targeting polypeptide transporters.</p>

<p>Leucic acid (α-Hydroxyisocaproic acid) is an amino acid widely found in plants and animals that prevents muscle loss and is broken down into glucose.</p>

<p>Methionine (D-Methionine) (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor</p>

<p>Tetrasodium glutamate diacetate (Glutamate diacetate tetrasodium) is a degradable chelating agent used as a dietary ingredient.</p>

<p>(+)-Longifolene is a naturally occurring.</p>

<p>Alcohol dehydrogenase is a widely distributed zinc-containing enzyme involved in the detoxification mechanism of environmental alcohols.</p>

<p>Vardenafil (Vivanza) is an oral therapy for the treatment of erectile dysfunction.</p>

<p>Oleamide (Oleic acid amide) is an endogenous fatty acid amide and can be used in the synthesis of de novo in the mammalian nervous system.</p>

<p>Ethyl cis-4,7,10,13,16,19-Docosahexaenoate is DHA's ethyl ester, concentrated from tuna oil via alcoholysis.</p>

<p>3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is a metabolite present in type I diabetic patients that has the property of regulating membrane</p>

<p>Stability Hygroscopic<br>Applications Retrorsine N-oxide is a pyrrolizidine alkaloid that is naturally found in Senecio isatideus, a flowering plant that is native to the Netherlands. Retrorsine N-oxide is also known to raise blood pressure and can induce abnormal changes in the liver if ingested by animals or humans.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cooper, R.: Trop. Anim. Health Pro., 39, 439 (2007); Mattocks, A.: Xenobiotica, 1, 563 (1971); Neumann, C. &amp; Boland, W.: Helv. Chim. Acta, 73, 754 (1990); Vera, R., et al.: J. Essent. Oil Res., 6, 21 (1994)<br></p>

<p>"(S)-(−)-Perillyl alcohol, a lavender monoterpene, inhibits Ras farnesylation, promotes apoptosis, and has anti-cancer effects."</p>

<p>Adenylate (Adk), a phosphotransferase enzyme, catalyzes adenosine phosphates and regulates cellular energy.</p>

<p>Estrone-d2 is a deuterated compound of Estrone. Estrone has a CAS number of 53-16-7. Estrone is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.</p>

BISPHENOL-A-2,2',3,3',5,5',6,6'-d8 is a deuterated compound of BISPHENOL-A. BISPHENOL-A has a CAS number of 80-05-7. Bisphenol A is a starting material for the synthesis of plastics, primarily certain polycarbonates and epoxy resins, as well as some polysulfones and certain niche materials. It exhibits estrogen-mimicking, hormone-like properties.

<p>Estrone-d4 3-Sulfate Sodium Salt is a deuterated compound of Estrone 3-Sulfate Sodium Salt. Estrone 3-Sulfate Sodium Salt has a CAS number of 438-67-5.</p>

<p>sn-Glycero-3-phosphocholine, a choline source in the brain and milk, may treat Alzheimer's/dementia and improve cognitive recovery post-stroke.</p>

<p>Urocanic acid (4-Imidazoleacrylic acid), synthesized in the epidermis, functions as a primary absorber of ultraviolet (UV) radiation in mammalian skin.</p>

<p>Cysteinylglycine (Cys-Gly), is a biologically important compound since it is formed during the γ-glutamyl cycle. It is a L-cysteinyl peptide, that can be used in the studies of many peptides and important proteins.</p>

<p>Calenduloside E (Silphioside F) exhibits hypoglycemic activities by suppressing the transfer of glucose from the stomach to the small intestine and by</p>

<p>5-Hydroxymethylcytosine (5hmC), a modified cytosine, is a sixth base of DNA and aids in active DNA demethylation.</p>

<p>L-Dehydro Ascorbic Acid, an oxidized ascorbic acid, crosses the blood-brain barrier for stroke protection.</p>

<p>Flavin adenine dinucleotide disodium salt (FAD sodium salt) is a coenzyme that facilitates the electron transfer of flavin enzymes in cellular redox reactions.</p>

<p>Hexadecanal (Palmitaldehyde) is a free fatty aldehyde present in animals.</p>

<p>1-Methyl-L-histidine (3-(1-Methylimidazol-4-yl)-L-alanine) is a natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown.</p>

<p>GS-9851, a HCV nonstructural protein 5B (NS5B) inhibitor, is used potentially for the treatment of HCV infection.</p>

<p>Olopatadine is an antihistamine and anti-allergy medication for itchy eyes, also possibly treats red skin syndrome.</p>

<p>Prosulfocarb, a thiocarbamate herbicide, is widely used in winter cereals.</p>

<p>Deacetyldiltiazem is a metabolite product of Diltiazem which is a coronary vasodilator, and is present in the plasma of individuals taking Diltiazem.</p>

<p>Meclofenamate sodium: a strong NSAID inhibiting leukocyte function—chemotaxis, degranulation, and radical production.</p>

<p>2,4-D-methyl is a carboxylesterase in herbicide bioactivation.</p>

<p>Verdantiol is a flavanol.</p>

<p>Normetanephrine, an endogenous metabolite found in cerebrospinal fluid, has applications in hypertension research [1] [2].</p>

<p>Argininosuccinic acid can be obtained during the urea cycle from citrulline, aspartate, and ATP by argininosuccinic acid synthetase.</p>

<p>Larsucosterol, a cholesterol metabolite in human liver, modulates lipid synthesis, inflammation, and apoptosis gene transcription.</p>

<p>NE58018 is a compound which has bioactive.</p>

<p>Mannose 1-phosphate, an endogenous metabolite, serves as a substrate for the enzyme GDP-mannose pyrophosphorylase to synthesize GDP-Man [1].</p>

<p>N6-Etheno 2'-deoxyadenosine is used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.</p>

<p>Cyclanilide is a plant growth regulator. It is used in cotton at different stages of growth.</p>

<p>Deacyl acebutolol is the major metabolite of Acebutolol.</p>

<p>12-Doxyl stearic acid, a derivative of stearic acid featuring a 4,4-dimethyl-3-oxazolinyloxy (DOXYL) group, functions as a hydrophobic spin label. This compound is prevalently utilized in research to investigate the molecular characteristics of membranes and hydrophobic proteins.</p>