Acides aminés (AA)

Applications 4-Benzyloxy-3-methoxybenzoic Acid is used in the synthesis of Hsp90 inhibitors as EGCG analogues. Also used in the preparation of vanillates exhibiting cytostatic properties towards cancel cells resistant to pro-apoptotic stimuli.
References Khandelwal, A. et al.: J. Org. Chem., 78, 7859 (2013); Lamoral-Theys, D. et al.: Bioorg. Med. Chem., 18, 3823 (2010);

Applications 2-Methylresorcinol (cas# 608-25-3) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Used in peptide synthesis.
References Flohr, S., et al.: Chem. Eur. J., 5, 669 (1999), Kadereit, D., et al.: ChemBioChem., 1, 144 (2000), Volkert, M., et al.: Biol. Chem., 382, 1133 (2001),

Applications 2,6-Diaminopimelic Acid is useful in biological studies involving amino acids and amino sugars as molecular indicators of the origins of organic matter in buried tephra soils.
References Hobara, S., et al.: Geoderma, 373, 114449 (2020)

Applications Ethametsulfuron-methyl is a regulator of the early steps of complement activation on mucosal surfaces. It can be used in combination treatment of ohmic heating with various essential oil components for inactivation of food-​borne pathogens in buffered peptone water and salsa.
References Kim, S. S., et al.: Food Control, 80, 29 (2017); Reichhardt, M. P., et al.: Front Immunol, 7, 85 (2016)

Applications Useful for the synthesis of Biocytin containing peptides to study the mechanism of reactions catalyzed by biotin - containing enzymes.
References Bodanszky, M., and Fagan, D.T.: J. Am. Chem. Soc., 99, 235 (1977)

Applications L-Lysine-2,6,6-d3 HCl is a useful isotopically labeled compound of L-Lysine HydrochlorideDISCONTINUED PLEASE SEE L486915 (L468923)

Applications 2-ethyl-6-methylpyrazine (cas# 13925-03-6) is a useful research chemical.

Applications N-Methyl-N-trimethylsilylacetamide, is a powerful silylating agent for polar compounds.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Melanie MacGregor-Ramiasa et. al; Acta biomaterialia, 56, undefined (2017-2-25)

Applications 2-(Diphenylmethoxy)-N-methylethylamine is used in the pereparation of H1 and H2 receptor antagonists containing Diphenhydramine (D486900) derivatives. Diphenhydramine is a H1-histamine receptor antagonist. Diphenhydramine (D486900) is categorized as an antihistaminic; sedative, hypnotic.
References Wolf, C. et al.: Archiv. de Pharm., 329, 87 (1996); Gruhzit, O.M., et al.: J. Pharmacol. Exp. Ther., 89, 227 (1947), Holcomb, I.J., et al.: Anal. Profiles Drug Subs., 3, 173 (1974), Scavone, J.M., et al.: J. Clin. Pharmacol., 38, 603 (1998),

Applications N-Boc-L-proline is a useful synthetic intermediate. It is used to synthesize Daclatasvir (D101500) which nhibits the HCV protein NS5A. Daclatasvir (D101500) can be used as a drug candidate for the treatment of hepatitis C (HCV).
References Gao, M., et al.: Nature, 465(7294), 96 (2010); Bell, T. W., Chem. Med. Chem., 5(10), 1663 (2010);

Stability Hygroscopic
Applications 4-Chloro-2-methylaniline Hydrochloride (cas# 3165-93-3) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 3-(2-Methoxy-5-methylphenyl)-3-phenyl-propanoic Acid (cas# 109089-77-2) is a compound useful in organic synthesis.

Applications Important compounds in coffee aroma.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 5-amino-2-methyl-benzenesulfonamide (cas# 6973-09-7) is a useful research chemical.

Applications 1,2:4,5-bis-O-(1-Methylethylidene)-β-D-Fructopyranose is a reagent in the synthesis of antibacterial/antifungal monosaccaride esters. Also used in the synthesis of antihyperlipidemic novel compounds involving glycosyl fructose derivatives.
References Shen, Y. et al.: Molecules, 17, 8661 (2012); Tiwari, P. et al.: Bioorg. Med. Chem. Lett., 16, 6028 (2006);

Applications 1-Methyl-1h-1,2,4-triazol-3-amine (cas# 49607-51-4) is a useful research chemical.

Applications 4-Methylphenethylamine is the monomethylated derivative of phenethylamine (P321335) and can readily cross the blood-brain barrier in rats showing a brain-uptake index of 98%.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mosnaim, A. D., et al.: Neurochem. Res., 38, 842 (2013)

Applications Methionine-methyl-d3 is the labeled Methionine-methyl, a useful building block.

Applications 2-Oxo-3-methylbutanoic acid (cas# 759-05-7) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Stability Hygroscopic
Applications A labelled metabolite of Methyl isocyanate.
References Slatter, J. G., et al.: Chem. Res. Toxicol., 4, 157 (1991),

Applications (3-Methyl-2-butenyl)triphenyl-phosphonium Bromide (cas# 1530-34-3 ) is a compound useful in organic synthesis.

Applications The main labelled metabolite of o-xylene.
References Gregus, Z., et al.: Drug Metab. Dispos., 26, 1082 (1998), Gregus, Z., et al.: Xenobiotica, 29, 547 (1999), Gonzalez-Reche, L., et al.: Arch. Toxicol., 77, 80 (2003),

Applications An efficient reagent for aminoacylations. Used in the synthesis of chiral Pilocarpine analogs via a C-8 ketone intermediate.
References Enz, A., et al.: Life Sci., 52, 513 (1993), Felder, C., et al.: J. Med. Chem., 43, 4333 (2000),

Applications (S)-2-METHYL GLYCIDOL (cas# 86884-90-4) is a useful research chemical.

Applications 6-Methylmercaptopurine Riboside (cas# 342-69-8) is a compound useful in organic synthesis.

Stability Hygroscopic
Applications 3-Methyl-2-oxovaleric acid calcium salt (cas# 66872-75-1) is a useful research chemical.

Applications It can be degraded efficiently by the QL-degrading bacteria.
References Shukla, O., et al.: Microbios., 59, 47 (1989), Oh, Y; Biotechnol Bioeng 1994, 44, 533,,,

Applications 3-[(4-Methylphenyl)amino]phenol, is the reagent that can be used in the preparation of Phentolamine Hydrochloride (P302550), an adrenergic blocking agent, and an antihypertensive
References Meier, R., et al.: Proc. Soc. Exp. Biol. Med., 71, 70 (1949), Spergel, G., et al.: J. Am. Med. Assoc., 211, 266 (1970), Gould, L. and Reddy, C.V.R.: Am. Heart J., 92, 397 (1976)

Applications 2-methyl-1-[4-(trifluoromethyl)phenyl]propan-1-one (cas# 64436-58-4) is a useful research chemical.

Stability Air Sensitive
Applications N-Methyl-L-cysteine Hydrochloride is an intermediate used to prepare analogs of pyochelin (P840365), a siderophore of Pseudomonas aeruginosa.
References Rivault, F., et al.: Tetrahedron, 60, 12139 (2004); Noel, S., et al.: Bioorgan. Chem. Lett., 24, 132 (2014); Ankenbauer, R., et al.: J. Bacteriol., 170, 5344 (1988)

Applications L-Tryptophan-d3 is a deuterium labelled amino acid, which is a protein building block. The unlabelled L-Tryptophan (T947210) is also available.
References Goze, C., et al.: Eur. J. Pharmacol., 643, 153 (2010), Bhandare, P., et al.: J. Chem. Pharm. Res., 2, 372 (2010),

Applications 3-Acetyl-2-methylquinoxaline is an intermediate in the synthesis of Desoxyquinocetone which is a metabolite of the veterinay drug Quinocetone.
References Li, Y. et al.: J. AOAC Int., 91, 1494 (2008); Liu, Z.-Y. et al.: Anal. Bioanal. Chem., 396, 1259 (1271);

Applications Used in the synthesis of selective β-adrenergic blocker Metoprolol.
References Su, W., et al.: J. Chem. Res., 6, 414 (2004),

Applications DL-Proline-2,5,5-d3 (CAS# 784086-28-8) is a useful isotopically labeled research compound.

Applications 2-Methylindoline is an intermediate in the production of various indole derivatives
References Severino, B., et al.: Bioorg. Med. Chem., 16, 6009 (2008); Zlotos, D., et al.: J. Med. Chem., 52, 826 (2009);

Applications 2-Methylbutane is a useful synthetic intermediate. It was used in the synthesis of β-chiral sulfonamides.
E3
References Chuprakov, S., et al.: J. Am. Chem. Soc., 133, 10352 (2011);