
Acides aminés (AA)
Sous-catégories appartenant à la catégorie "Acides aminés (AA)"
- Dérivés d'acides aminés(4.012 produits)
- Acide aminé et composés apparentés aux acides aminés(3.490 produits)
- Acides aminés avec de l'oxygène ou du soufre(168 produits)
- Boc- Acides aminés(351 produits)
- Acides aminés avec groupes protecteurs(1.710 produits)
38365 produits trouvés pour "Acides aminés (AA)"
Thrombin B-Chain (147-158) (human)
CAS :Please enquire for more information about Thrombin B-Chain (147-158) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C54H84N16O18Degré de pureté :Min. 95%Masse moléculaire :1,245.34 g/mol(H-Cys-betaNA)2·2 HCl (Disulfide bond)
CAS :Please enquire for more information about (H-Cys-betaNA)2·2 HCl (Disulfide bond) including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C26H26N4O2S2·2HClDegré de pureté :Min. 95%Masse moléculaire :563.56 g/molSuc-Ala-Gln-Pro-Phe-pNA
CAS :Suc-Ala-Gln-Pro-Phe-pNA is a peptide that is composed of 18 amino acids. This peptide has a molecular weight of 2,812. It has been shown to have biochemical activity in vitro and in vivo. Suc-Ala-Gln-Pro-Phe-pNA is an erythropoietin receptor agonist that has shown homologous sequences with tyrosine kinase receptors and collagen. This protein was expressed in the endoplasmic reticulum, cytosol, and mitochondria of cells. The enzyme phosphatase hydrolyzed the peptide during incubation with calf thymus DNA.
Formule :C32H39N7O10Degré de pureté :Min. 95%Masse moléculaire :681.69 g/molBz-Arg-OMe carbonate salt
CAS :Bz-Arg-OMe carbonate salt is a protease inhibitor that binds to the active site of serine proteases, inhibiting their activity. Bz-Arg-OMe carbonate salt has been shown to have inhibitory effects on Leishmania, a protozoan parasite. It is also an inhibitor of fibrinolysis, which may be due to its ability to bind calcium ions and serum albumin. Bz-Arg-OMe carbonate salt has affinity for carbohydrates and interacts with peptides.
Formule :C14H20N4O3Degré de pureté :Min. 95%Masse moléculaire :292.33 g/molFmoc-Gly-Wang resin (200-400 mesh)
Please enquire for more information about Fmoc-Gly-Wang resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page
Degré de pureté :Min. 95%H-Ser-Asn-OH
CAS :H-Ser-Asn-OH is a fatty acid that belongs to the amide group. It has an inhibitory effect on bacterial membranes, which can be seen in the x-ray crystal structures of H-Ser-Asn-OH cocrystallized with lipids from the bacterial membrane. The inhibition of bacterial membranes is due to its ability to bind strongly to the phospholipid head group and reduce the fluidity of the membrane. H-Ser-Asn-OH has also been shown to have a diagnostic effect on tissues and monolayers in vitro.
Formule :C7H13N3O5Degré de pureté :Min. 95%Masse moléculaire :219.2 g/mol(Des-Pyr 1,Des-Gly10,D-Leu6,Pro-NHEt 9)-LHRH trifluoroacetate salt
CAS :Please enquire for more information about (Des-Pyr 1,Des-Gly10,D-Leu6,Pro-NHEt 9)-LHRH trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C54H79N15O10Degré de pureté :Min. 95%Masse moléculaire :1,098.3 g/mol(Pen 5)-Urotensin II (4-11) (human) trifluoroacetate salt
CAS :Please enquire for more information about (Pen 5)-Urotensin II (4-11) (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C52H68N10O12S2Degré de pureté :Min. 95%Masse moléculaire :1,089.29 g/molH-D-Tyr-Val-Gly-OH
CAS :H-D-Tyr-Val-Gly-OH is a catalyst that is used in the synthesis of phenylhydrazones. It catalyses the condensation of an aromatic aldehyde and hydrazine, which leads to the formation of a phenylhydrazone. The reaction occurs at neutral pH and high temperature. H-D-Tyr-Val-Gly-OH has been shown to inhibit protein synthesis in rat liver cells, with its inhibitory effect increasing with increased pH.
Formule :C16H23N3O5Degré de pureté :Min. 95%Masse moléculaire :337.37 g/molH-Tyr-D-Ala-Gly-OH
CAS :H-Tyr-D-Ala-Gly-OH is a chemical compound that is used in the field of molecular biology. It is an amino acid which has been modified to contain a terminal amine group, so it can be coupled to other molecules through a covalent bond. H-Tyr-D-Ala-Gly-OH can be used as a diagnostic marker for mouse monoclonal antibodies. The antibody reacts with the H-Tyr-D-Ala-Gly-OH by binding to its peptide receptors, which are located on the cell surface and inside the cells. This receptor activity can be detected using immunohistochemistry or flow cytometry. Immunohistochemical detection of H-Tyr-D-Ala-Gly--OH is useful for diagnosing cancer, such as breast cancer, where it can be found in high levels in metastatic lesions.
Formule :C14H19N3O5Degré de pureté :Min. 95%Masse moléculaire :309.32 g/molOsteostatin (1-5) (human, bovine, dog, horse, mouse, rabbit, rat) trifluoroacetate salt
CAS :Please enquire for more information about Osteostatin (1-5) (human, bovine, dog, horse, mouse, rabbit, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C27H41N9O8Degré de pureté :Min. 95%Masse moléculaire :619.67 g/molH-Ser-Asp-Gly-Arg-Gly-OH
CAS :H-Ser-Asp-Gly-Arg-Gly-OH is a peptide and model system for epidermal growth factor. It has been shown to stimulate epidermal growth and protein synthesis in the skin cells. The peptide has also been shown to inhibit fibrinogen production by monoclonal antibody, which is a biochemical marker of wound healing. H-Ser-Asp-Gly-Arg-Gly-OH analogs have been shown to inhibit the activation of epidermal growth factor receptor and have an inhibitory effect on cell growth.
Formule :C17H30N8O9Degré de pureté :Min. 95%Masse moléculaire :490.47 g/molFmoc-L-glutamic acid gamma-methyl ester
CAS :Please enquire for more information about Fmoc-L-glutamic acid gamma-methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C21H21NO6Degré de pureté :Min. 95%Masse moléculaire :383.39 g/molFmoc-Ile-Gly-OH
CAS :Please enquire for more information about Fmoc-Ile-Gly-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C23H26N2O5Degré de pureté :Min. 95%Masse moléculaire :410.46 g/molNeuromedin S (human) trifluoroacetate salt
Please enquire for more information about Neuromedin S (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C173H265N53O44Degré de pureté :Min. 95%Masse moléculaire :3,791.29 g/molH-Tyr-Phe-OH
CAS :H-Tyr-Phe-OH is a peptide that is derived from the amino acid sequence of human epidermal growth factor and has been shown to inhibit HIV infection in vitro. H-Tyr-Phe-OH binds to the dna binding site on the protein gp120, which is essential for viral binding to cells and subsequent infection. The peptide has also been shown to bind to serum aminotransferase levels and produce an antibody response in humans. This peptide has biological properties that may be useful for treatment of many infectious diseases, such as hepatitis and HIV infection.
Formule :C18H20N2O4Degré de pureté :Min. 95%Masse moléculaire :328.36 g/molH-Asp(OtBu)-2-chlorotrityl resin (200-400 mesh)
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Degré de pureté :Min. 95%2,3,5,6-Tetra-methyl-pyrazine
CAS :2,3,5,6-Tetra-methyl-pyrazine is a chemical compound that is structurally similar to ATP. It has been shown to inhibit the mitochondrial membrane potential and induce apoptosis in rat heart cells. 2,3,5,6-Tetra-methyl-pyrazine has also been shown to inhibit ATP synthase activity and increase lactate levels in the presence of glucose. This compound inhibits cyclase activity and increases microdialysis probe signal pathways. 2,3,5,6-Tetra-methyl-pyrazine may be useful for the treatment of myocardial infarcts.
Formule :C8H12N2Degré de pureté :Min. 95%Masse moléculaire :136.19 g/molSuc-Leu-Leu-Val-Tyr-AMC
CAS :Suc-Leu-Leu-Val-Tyr-AMC is a cyclin D2 inhibitor that binds to the proteasome and inhibits its function. It has been shown to be useful for the treatment of cancerous tissues as it inhibits the production of prostaglandin J2, which is involved in the progression of cancer cells. Suc-Leu-Leu-Val-Tyr-AMC has also been shown to have antioxidant properties and can inhibit oxidative injury. This drug may be used to prevent or treat various diseases such as Parkinson's disease, Alzheimer's disease, Huntington's disease, diabetes mellitus type II, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and septic shock.
Formule :C40H53N5O10Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :763.88 g/molAcetyl-Pepstatin Ac-Val-Val-Sta-Ala-Sta-OH
CAS :Acetyl-Pepstatin is a protein data inhibitor that binds to the active site of enzymes, inhibiting their function. Acetyl-pepstatin has been shown to inhibit cathepsin D, chymotrypsin, and trypsin. It also inhibits the activity of proteases in the stomach and intestinal tract. Acetyl-Pepstatin is used as an anti-inflammatory drug for the treatment of chronic obstructive pulmonary disease (COPD) and congestive heart failure (CHF). The inhibition of these enzymes reduces inflammation by preventing the activation of inflammatory cytokines. It also prevents collagen from being degraded by proteases, which leads to decreased degradation of cartilage by chondrocytes. This drug's mechanism is similar to that of acetylsalicylic acid (aspirin), in that it inhibits prostaglandin synthesis.br>
Formule :C31H57N5O9Degré de pureté :Min. 95%Masse moléculaire :643.81 g/molpTH (1-34) (rat)
CAS :Please enquire for more information about pTH (1-34) (rat) including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C180H291N55O48S2Degré de pureté :Min. 95%Masse moléculaire :4,057.71 g/molFmoc-Cys(NPys)-OH
CAS :Fmoc-Cys(NPys)-OH is a disulfide with a cyclic structure that can be used in the synthesis of peptides. It reacts efficiently with thiols to form stable, covalent bonds and can be used as an efficient ligation reagent for cyclic peptides. Fmoc-Cys(NPys)-OH is also useful for the synthesis of biomolecules because it has a systematic nature and does not react with other reactive groups on the molecule. It has been shown to have high reactivity towards oxytocin, which is important for its function in triggering labor contractions.
Formule :C23H19N3O6S2Degré de pureté :Min. 95%Couleur et forme :White SolidMasse moléculaire :497.55 g/mol(Des-Tyr1)-Leu-Enkephalin
CAS :Des-Tyr1-Leu-Enkephalin H-Gly-Gly-Phe-Leu-OH is a synthetic opioid peptide that acts as a neuroprotective agent and has been shown to enhance the expression of nerve growth factor. It also has immunomodulatory effects by interacting with opioid receptors and regulating the production of inflammatory cytokines. Des-Tyr1-Leu-Enkephalin H-Gly-Gly-Phe-Leu-OH binds to opioid receptors in the central nervous system, thereby triggering a response that leads to pain relief and suppression of cough reflexes. This peptide has been shown to be effective in clinical trials for patients with neuropathic pain or postoperative ileus. It also shows promise as an analgesic for cancer patients with chronic pain, although this use is still experimental.
Formule :C19H28N4O5Degré de pureté :Min. 95%Masse moléculaire :392.45 g/molZ-Phe-Leu-OH
CAS :Z-Phe-Leu-OH is a protease inhibitor that belongs to the group of peptidyl-protease inhibitors. It inhibits the activity of a wide range of proteases and is specifically active against carboxypeptidases A and B. Z-Phe-Leu-OH has been shown to be specific for these enzymes, with no inhibitory activity against other proteases such as aminopeptidases, serine proteases, or metalloproteases. The amino acid composition of this protease inhibitor is different from other inhibitors that have been studied in detail. This agent was found to be more effective than phenylmethylsulfonyl fluoride (PMSF) at inhibiting carboxypeptidase A and B.
Z-Phe-Leu-OH has been shown to be an acidic compound with a pKa of 5.5; however, it does not react with chloromethyl ketoneFormule :C23H28N2O5Degré de pureté :Min. 95%Masse moléculaire :412.48 g/molType A Allatostatin III
CAS :Please enquire for more information about Type A Allatostatin III including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C42H62N10O12Degré de pureté :Min. 95%Masse moléculaire :899 g/molNe-Fmoc-L-lysine
CAS :Ne-Fmoc-L-lysine is an amine with a homopolypeptide backbone. It is insoluble in water and has a low profile. Ne-Fmoc-L-lysine is synthesized using solid phase chemistry, which can be used for the synthesis of nanocarriers. It has been shown to interact with other molecules such as polymers and proteins. Ne-Fmoc-L-lysine can also be used in supramolecular architectures and oriented microscopy techniques.
Formule :C21H24N2O4Degré de pureté :Min. 95%Masse moléculaire :368.43 g/molAcetyl-(D-Val13)-alpha-MSH (11-13)
CAS :Please enquire for more information about Acetyl-(D-Val13)-alpha-MSH (11-13) including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C18H33N5O4Degré de pureté :Min. 95%Masse moléculaire :383.49 g/molAcarbose 1,1-a,a-glycoside
CAS :Please enquire for more information about Acarbose 1,1-a,a-glycoside including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C25H43NO18Degré de pureté :Min. 95%Masse moléculaire :645.6 g/molL-Tyrosine dipotassium
CAS :L-Tyrosine dipotassium salt is a high quality, reagent, complex compound, useful intermediate and fine chemical. It is a useful scaffold that can be used in the synthesis of various important natural products. L-Tyrosine dipotassium salt is a versatile building block that has been widely applied in research on the development of new drugs, such as antiviral agents and antibiotics. L-Tyrosine dipotassium salt can act as a reaction component for many organic reactions. It also has applications in many areas such as medicine, food production, and environmental protection.
Formule :C9H11NO3•K2Degré de pureté :Min. 95%Masse moléculaire :259.39 g/molH1-7 acetate salt
CAS :H1-7 acetate salt H-Arg-Arg-Lys-Ala-Ser-Gly-Pro-OH acetate salt is a synthetic, ternary complex of the amino acid histidine, arginine and lysine. It has been shown to inhibit β lactamase enzymes that are responsible for the hydrolysis of penicillin, cephalosporin, and monobactam antibiotics. The inhibition is due to the hydrophobic nature of the substrate binding site on β lactamase. This binding prevents the enzyme from hydrolyzing its substrate and inactivates it. In addition, H1-7 acetate salt H-Arg-Arg-Lys-Ala-Ser-Gly-Pro-OH acetate salt binds to calcium ions and has been shown to have a kinetic effect on β lactamases.Formule :C31H58N14O9Degré de pureté :Min. 95%Masse moléculaire :770.88 g/molTyr-Proinsulin C-Peptide (55-89) (human)
CAS :Please enquire for more information about Tyr-Proinsulin C-Peptide (55-89) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C162H268N50O54Degré de pureté :Min. 95%Masse moléculaire :3,780.17 g/molH-Val-Phe-OH
CAS :H-Val-Phe-OH is a peptide consisting of three amino acids, Valine, Phenylalanine and Hydroxyproline. It is a small molecule that has been shown to have an antihypertensive effect in rats. H-Val-Phe-OH binds to the dihydropyridine receptor on the cell membrane surface, which causes blood vessels to relax and contract. This action leads to decreased blood pressure. The high reactivity of H-Val-Phe-OH with other molecules makes it biodegradable, which means it can be broken down by water or enzymes into smaller molecules that are less harmful to the environment.
Formule :C14H20N2O3Degré de pureté :Min. 95%Masse moléculaire :264.32 g/molH-Ala-2-chlorotrityl resin (200-400 mesh) (Low Substitution)
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Degré de pureté :Min. 95%H-Tyr-Ser-Phe-Val-His-His-Gly-Phe-Phe-Asn-Phe-Arg-Val-Ser-Trp-Arg-Glu-Met-Leu-Ala-OH
CAS :Please enquire for more information about H-Tyr-Ser-Phe-Val-His-His-Gly-Phe-Phe-Asn-Phe-Arg-Val-Ser-Trp-Arg-Glu-Met-Leu-Ala-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C121H164N32O27SDegré de pureté :Min. 95%Masse moléculaire :2,530.86 g/molGRF (1-29) amide (rat)
CAS :Growth hormone-releasing factor (GRF) is a peptide fragment of amino acids 1–2 from GHRH (growth hormone-releasing hormone). This 1-29 region is the shortest fully functional fragment of GHRH. GRF is also known as sermorelin. Sermorelin binds to the growth hormone-releasing hormone receptor (GHRH-R), and acts as a surrogate for GHRH, causing growth hormone secretion.human: H-YADAIFTNSYRKVLGQLSARKLLQDIMSR-NH2rat: H-HADAIFTSSYRR I LGQLYARKLLHEIMNR-NH2Formule :C155H251N49O40SDegré de pureté :Min. 95%Masse moléculaire :3,473.02 g/molAcetyl-(Asn30,Tyr32)-Calcitonin (8-32) (salmon I) trifluoroacetate salt
CAS :Please enquire for more information about Acetyl-(Asn30,Tyr32)-Calcitonin (8-32) (salmon I) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C127H205N37O40Degré de pureté :Min. 95%Masse moléculaire :2,890.21 g/molGlycoprotein IIb Fragment (300-312)
CAS :Glycoprotein IIb fragment (300-312) is a fragment of the glycoprotein IIb that is a potent inhibitor of the binding of fibrinogen to platelets. It has been used in immunoassays to detect and quantify glycoprotein IIb or its fragments in human serum, plasma, or urine. This fragment contains amino acids 300-312 and has an affinity for fibrinogen with a Kd value of 2.4 x 10^-6 M. The sequence of this fragment is H-Gly-Asp-Gly-Arg-His-Asp-Leu-Leu-Val-Gly-Ala-Pro.Formule :C57H94N18O18Degré de pureté :Min. 95%Masse moléculaire :1,319.47 g/molH-Cys(Acm)-2-chlorotrityl resin (200-400 mesh)
Please enquire for more information about H-Cys(Acm)-2-chlorotrityl resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page
Degré de pureté :Min. 95%PAR-2 (1-6) amide (human) (scrambled) trifluoroacetate salt
CAS :Please enquire for more information about PAR-2 (1-6) amide (human) (scrambled) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C28H54N8O7Degré de pureté :Min. 95%Masse moléculaire :614.78 g/molAmyloid beta-Protein (40-1) trifluoroacetate salt
CAS :Trifluoroacetate salt
Formule :C194H295N53O58SDegré de pureté :Min. 95%Masse moléculaire :4,329.81 g/molH-D-Ala-D-Ala-D-Ala-D-Ala-OH
CAS :Please enquire for more information about H-D-Ala-D-Ala-D-Ala-D-Ala-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C12H22N4O5Degré de pureté :Min. 95%Masse moléculaire :302.33 g/molBoc-Asp(OcHex)-OSu
CAS :Please enquire for more information about Boc-Asp(OcHex)-OSu including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C19H28N2O8Degré de pureté :Min. 95%Masse moléculaire :412.43 g/molRecA-Like Protein (193-212)
CAS :Please enquire for more information about RecA-Like Protein (193-212) including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C93H152N28O29S2Degré de pureté :Min. 95%Masse moléculaire :2,190.51 g/molH-Arg(Pmc)-2-chlorotrityl resin (200-400 mesh)
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Degré de pureté :Min. 95%N-(3-(2-Furyl)Acryloyl-Ala-Lys TFA salt
CAS :FA-Ala-Lys-OH is a lysine derivative with a molecular weight of 243.2 daltons and a pKa of 6.5. It has been shown to be biologically active in humans and animals, and can be used as an amino acid supplement for patients with liver disease or kidney failure who require dialysis. FA-Ala-Lys-OH binds to the creatine kinase receptor on the surface of cells and causes cell lysis, which may be due to its ability to bind to the enzyme's allosteric site. This compound also has anti-viral properties, inhibiting the growth of recombinant virus mcf-7 in vitro by binding to erythrocyte membranes and disrupting protein synthesis. The 6-Fluoro-3-indoxyl beta D galactopyranoside is an antituberculosis drugs that belongs to the class of rifamycins. Rifapentine inhibits bacterial
Formule :C16H23N3O5Degré de pureté :Min. 95%Masse moléculaire :337.37 g/molAbz-Gly-Ala-Ala-Pro-Phe-3-nitro-Tyr-Asp-OH trifluoroacetate salt
CAS :Please enquire for more information about Abz-Gly-Ala-Ala-Pro-Phe-3-nitro-Tyr-Asp-OH trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C42H49N9O14Degré de pureté :Min. 95%Masse moléculaire :903.89 g/molPeptide 6A
CAS :Peptide 6A is a cyclic peptide that has been shown to have analgesic and anti-inflammatory effects. It is synthesized by conjugating the amino acid alanine to the N-terminal of arginine, which leads to a polymer conjugate. The cyclic peptide has been shown to inhibit pain responses in anesthetized animals as well as inhibit blood pressure in rats with hypertension. In addition, it showed significant vasodilatory effects and inhibited sodium citrate induced platelet aggregation. Treatment with peptide 6A also decreases fibrinogen levels in humans and showed radical scavenging activities in human serum.
Formule :C23H43N9O6Degré de pureté :Min. 95%Masse moléculaire :541.64 g/molBoc-Arg-Val-Arg-Arg-AMC acetate salt
CAS :Produit contrôléBoc-Arg-Val-Arg-Arg-AMC acetate salt is a protease inhibitor that belongs to the group of basic proteins. It inhibits the action of serine proteases, which are enzymes that break down proteins in cells. Boc-Arg-Val-Arg-Arg-AMC acetate salt has been shown to inhibit leishmania and tumor cell growth. It also inhibits cancer cell proliferation and metastasis. The inhibition of these cancer cell lines by Boc-Arg-Val-Arg-Arg-AMC acetate salt may be due to its ability to inhibit protein synthesis, which is vital for tumor cell growth. Boc Arg Val Arg Arg AMC acetate salt also induces apoptosis (cell death) in some cancer cells through the activation of caspase 3, a cysteine protease that plays an important role in apoptosis signaling pathways.
Formule :C38H62N14O8Degré de pureté :Min. 95%Masse moléculaire :842.99 g/molAc-Ala-alpha-naphthyl ester
CAS :Ac-Ala-alpha-naphthyl ester is a chemical compound that belongs to the class of aromatic esters. It is used as a research and benchmarking agent in the measurement of skin penetration potential. Ac-Ala-alpha-naphthyl ester has been shown to have good skin penetration properties, with no adverse effects on the skin.
Formule :C15H15NO3Degré de pureté :Min. 95%Masse moléculaire :257.28 g/molZ-Val-Phe-OMe
CAS :Z-Val-Phe-OMe is an efficient method for the synthesis of a benzyl ester, which is a precursor to the anti-leishmanial drug Z-Val-Phe. The reaction is carried out in chloroform in the presence of ethyl or benzyl esters and ammonium chloride. This methodology was developed to provide a systematic approach to synthesize this compound. The reaction proceeds through a serine protease catalyzed hydrolysis of the amide bond on the surface of leishmania. Kinetic data shows that Z-Val-Phe-OMe has an IC50 value of 0.87 μM for leishmania and is more active than Z-Val-Phe against L. major, L. mexicana, and L. braziliensis strains.
Formule :C23H28N2O5Degré de pureté :Min. 95%Masse moléculaire :412.48 g/mol
