Peptides

Myoglobin
Myoglobin 137-148 MHC II DRB1*03:01 is a short part of Myoglobin. Myoglobin is protein which binds oxygen or also iron in the skeletal muscle tissue.
Myoglobin 137-148 MHC II DRB1*03:01
Myoglobin 137-148 MHC II DRB1*03:01 is a classical peptide reference for the binding avec MHC II DRB1*03:01. Myoglobin 137-148 is often used to be in competition for study of the relative binding affinity.

Blocker of neuronal nicotinic acetylcholine receptors

Biotin-Ova (323-339) is the N-ter biotinylated version of Ova (323-339). Biotin-Ova (323-339) can be used in the analysis of antigen-specific T cells. Ovalbumin protein:
Ova (323-339) is an epitope of interest of the egg white albumen, which is widely used in allergy research. Ovalbumin is a glycoprotein that is sufficiently large and complex to be mildly immunogenic. Indeed, it has been demonstrated that Ovalbumin contains B-cell epitopes which are recognized by specific IgE antibodies and CD4 T cell epitopes restricted by the MHC I-Ad molecule in mice and by HLA-D molecule in human.
Applications of Ova (323-339):
Ova (323-339) allows to study bindings of class II MHC-peptide and T-cell activation in PBMCs by ELISPOT assays. In fact, this method quantifies peptide epitope specificity and IFN-γ releasing effector cells. It has been shown that Ova (323-339) was responsible for 25-35% of T-cell response of isolated BALB/c mouse. An investigation has demonstrated that Ova and Ova (323-339) induced similar lung inflammation and a Th2-like dominant immune response in mouse model.
Sequence: Biotin-ISQAVHAAHAEINEAGR

N3-H8 is a clickable CPP.

Clickable and fluorescent TAT peptide.

Biotin-SARS-CoV-2 Spike RBM 500-509 peptide is the biotinylated version of SARS-CoV-2 Spike RBM 500-509 peptide. SARS-CoV-2 Spike RBM 500-509 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Motif (RBM). Biotin-SARS-CoV-2 Spike RBM 500-509 peptide is useful for vaccine development and for structure-activity relationship studies
SARS-CoV-2 Spike (S) glycoprotein
Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells.
With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane.
SARS-CoV-2 Spike RBM:
The receptor-binding domain in SARS-CoV-2 Spike protein contains a receptor-binding motif RBM. SARS-CoV-2 Spike RBM is the main functional motif in RBD and allows contacts between the S protein and the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry.

SARS-CoV-2 Spike RBD 523-541 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Domain (RBD). SARS-CoV-2 Spike RBD 523-541 peptide is useful for vaccine development and for structure-activity relationship studies
SARS-CoV-2 Spike (S) glycoprotein
Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells.
With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane.
SARS-CoV-2 Spike RBD:
The receptor-binding domain in SARS-CoV-2 Spike protein allows binding to the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry.
SB-PEPTIDE also offers SARS-CoV-2 Spike RBD 523-541 (Biotin-LC) peptide

Secondary SIL peptide for Emicizumab  detection and quantification

Antagonization of αVβ3 integrin. Inhibition of cell proliferation, migration, invasion, and adhesion of αVβ3 expressing cells.

MOG(97-108) corresponds to amino acids 97 to 108 of the myelin oligodendrocyte glycoprotein (MOG).

SIL peptide for Infliximab detection and quantification

Simian Parainfluenza Virus type 5
V5 peptide is an epitope peptide of Simian Parainfluenza Virus type 5 (SV5) belonging to the Paramyxovirus family. SV5 causes some common human diseases, such as pneumonia, bronchiolitis, measles and mumps.
V5 peptide
V5 peptide represents amino acids 95-108 of SV5 corresponding to RNA polymerase alpha subunit and non-structural protein V. V5 peptide sequence was chosen because high-affinity antibodies can be produced in many different species. V5 peptide is useful as tag for protein purification and detection such as Western blotting, ELISA assays, immunofluorescence, immunoprecipitation assays and for protein purification.

Biotin-MAGE-A2 (157-166) is the N-ter biotinylated version of MAGE-A2 (157-166). Biotin-MAGE-A2 (157-166) can be used in the analysis of antigen-specific T cells. MAGE-A2 protein:
MAGE-A2 (157-166) is an epitope of Melanoma Antigen Gene A2 and is one of the most Cancer-Testis Antigens (CTA) overexpressed in tumors of different histological types, such as prostate cancer. Type of MAGE-A expressed in tumors cells varies according to the type of tumor. The expression of MAGE-A2 causes the proliferation of prostate cancer cells and decreases the chemosensitivity.
Applications of MAGE-A2 (157-166):
MAGE-A2 (157-166) is used to stimulate specific immune response, cytotoxic T cell response and to analyze the cytokine production in PBMCs by ELISPOT assay. In transgenic mouse, it has been demonstrated that MAGE-A2 (157-166) was capable of eliciting a CTL response presented by HLA-A*02:01 molecules. MAGE-A2 (157-166) has been reported to elicit CTL that could lyse tumor cell expressing both HLA-A*02:01 and MAGE-A2 by stimulation of peripheral blood mononuclear cells (PBMCs) with MAGE-A2 (157-166).
Sequence: Biotin-YLQLVFGIEV

Insecticidal peptide against Spodoptera frugiperda

Selective blocker of SK2 (KCa2.2) channels

NY-ESO-1 protein:
NY-ESO-1 (123-137) DRB1*04:01 is an epitope analogue of the New York esophageal squamous cell carcinoma-1, also named cancer testis. NY-ESO-1 is expressed in 82% of neuroblastomas and 46% of melanomas but also in many others solid tumors and hematological malignancies. That’s why, NY-ESO-1 peptides are attractive targets for specific immunotherapies and for the stimulation of human NY-ESO-1 specific CD8+ T cells.
Applications of NY-ESO-1 (123-137) DRB1*04:01:
Results of studies suggest after stimulation of NY-ESO-1 (123-137) DRB1*04:01 specific T cells and IFN- ELISPOT and chronium release assays that NY-ESO-1 (123-137) DRB1*04:01 can be an immunogenic epitope encoded by NY-ESO-1. NY-ESO-1 (123-137) DRB1*04:01 contains epitope capable of binding HLA-DR molecules.

Primary SIL peptide for Dupilimab detection and quantification

SARS-CoV-2 Spike RBD 371-394 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Domain (RBD). SARS-CoV-2 Spike RBD 371-394 peptide is useful for vaccine development and for structure-activity relationship studies
SARS-CoV-2 Spike (S) glycoprotein
Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells.
With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane.
SARS-CoV-2 Spike RBD:
The receptor-binding domain in SARS-CoV-2 Spike protein allows binding to the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry.
SB-PEPTIDE also offers SARS-CoV-2 Spike RBD 371-394 (Biotin-LC) peptide

SB-peptide offers the scrambled version of OVA 257-264. FILKSINE can be used as a negative control of OVA 257-264 studies.
SB-peptide offers also OVA 257-264 (see section OVA 257-264).
Ovalbumin protein:
OVA 257-264 (H-2Kb) is an epitope of interest of the egg white albumen, ovalbumin. Ovalbumin is a glycoprotein that is sufficiently large and complex to be mildly immunogenic. Indeed, it has been demonstrated that Ovalbumin contains B-cell epitopes which are recognized by specific IgE antibodies and CD4 T cell epitopes restricted by the MHC I-Ad molecule in mice and by HLA-D molecule in human.
Applications of OVA 257-264:
OVA 257-264 is used to stimulate T cells in PBMCs and to quantify peptide epitope specificity and IFN-γ releasing effector cells by ELISPOT assay. OVA 257-264 is also used to test new adjuvant in immunotherapeutic vaccine development. OVA 257-264 can form a stable hydrogel and stimulate a immune response. This reaction seems to be linked with OVA 257-264 property to self-assemble into a hydrogel.
Sequence:C45H74N10013

Biotin-SARS-CoV-2 Spike RBD 523-541 peptide is the biotinylated version of SARS-CoV-2 Spike RBD 523-541 peptide. SARS-CoV-2 Spike RBD 523-541 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Domain (RBD). Biotin-SARS-CoV-2 Spike RBD 523-541 peptide is useful for vaccine development and for structure-activity relationship studies
SARS-CoV-2 Spike (S) glycoprotein
Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells.
With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane.
SARS-CoV-2 Spike RBD:
The receptor-binding domain in SARS-CoV-2 Spike protein allows binding to the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry.

Biotin-SARS-CoV-2 Spike RBD 513-520 peptide is the biotinylated version of SARS-CoV-2 Spike RBD 513-520 peptide. SARS-CoV-2 Spike RBD 513-520 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Domain (RBD). Biotin-SARS-CoV-2 Spike RBD 513-520 peptide is useful for vaccine development and for structure-activity relationship studies
SARS-CoV-2 Spike (S) glycoprotein
Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells.
With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane.
SARS-CoV-2 Spike RBD:
The receptor-binding domain in SARS-CoV-2 Spike protein allows binding to the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry.

Biotin-SARS-CoV-2 Spike RBM 438-458 peptide is the biotinylated version of SARS-CoV-2 Spike RBM 438-458 peptide. SARS-CoV-2 Spike RBM 438-458 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Motif (RBM). Biotin-SARS-CoV-2 Spike RBM 438-458 peptide is useful for vaccine development and for structure-activity relationship studies
SARS-CoV-2 Spike (S) glycoprotein
Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells.
With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane.
SARS-CoV-2 Spike RBM:
The receptor-binding domain in SARS-CoV-2 Spike protein contains a receptor-binding motif RBM. SARS-CoV-2 Spike RBM is the main functional motif in RBD and allows contacts between the S protein and the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry.

Primary SIL peptide for Cetuximab detection and quantification

Nav1.3 activator

Blocker of Nav1.4 channels

Blocker of Nav1.7 channel

Blocker of voltage-gated sodium channels

Ryanodine receptors agonist

Biotin-SARS-CoV-2 Spike RBD 395-430 peptide is the biotinylated version of SARS-CoV-2 Spike RBD 395-430 peptide. SARS-CoV-2 Spike RBD 395-430 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Domain (RBD). Biotin-SARS-CoV-2 Spike RBD 395-430 peptide is useful for vaccine development and for structure-activity relationship studies
SARS-CoV-2 Spike (S) glycoprotein
Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells.
With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane.
SARS-CoV-2 Spike RBD:
The receptor-binding domain in SARS-CoV-2 Spike protein allows binding to the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry.

Blocker of A-type potassium channels

MOG (183-191) FVIVPVLGP

L-asparaginase is a drug that inhibits the production of asparagine, which is an amino acid that is used in the synthesis of proteins. It has been shown to be effective against T-cell lymphomas, as well as other cancers such as leukemia and colorectal cancer. L-Asparaginase has been shown to inhibit mitochondrial functions in blood samples from patients with prostate cancer. This inhibition may lead to cell death. L-Asparaginase binds to the sephadex G-100 column in a similar manner to sodium citrate and prevents the formation of polymers when it combines with ATP. The enzyme can also be found in primary cells and liver cells, where it causes hypoglycemia by inhibiting glucose production. L-Asparaginase also inhibits dna synthesis by binding to DNA polymerases, preventing their attachment to nucleotide triphosphates (e.g., ATP).

Gly-Pro-AMC is a peptide that can be used as a research tool to investigate protein interactions. Gly-Pro-AMC is an activator of ion channels and is able to inhibit ligand binding to receptor. It has been used in pharmacology for the study of protein interactions, ion channels, and receptors. Gly-Pro-AMC binds to the cell membrane and blocks the activation of potassium channels. It also inhibits ligand binding to receptors. This compound has been found in high purity with a CAS number of 67341-42-8.

Amyloid beta-protein (Aβ) is a peptide that is associated with Alzheimer's disease. It is a research tool for understanding the biology of Aβ. The Aβ peptide has been shown to activate a number of receptors and ion channels, including the nicotinic acetylcholine receptor, which may be due to its ability to bind to these proteins with high affinity. Amyloid beta-protein has also been shown to bind antibodies, which may be due to its ability to act as an antigen. Amyloid beta-protein inhibits the function of ion channels and can be used in pharmacological studies as a tool for understanding how this protein interacts with other proteins.

Boc-Gly-Arg-Arg-AMC is a research tool that has a high purity and is used in cell biology, antibody production, ion channels, and protein interactions. It is an inhibitor of ion channels, which can be used for pharmacology to study the function of ion channels. Boc-Gly-Arg-Arg-AMC has also been shown to inhibit binding between the ligand and receptor.

Bombesin is a small peptide that was first isolated from the skin of a frog, Bombina bombina, with homologs later found to be present in mammalian tissues, including the brain and gastrointestinal tract. It is a member of the bombesin-like peptide family, which includes several related peptides such as gastrin-releasing peptide (GRP) and neuromedin B.
Bombesin acts as a neuromodulator and regulates various physiological functions, including gastrointestinal motility and stimulation of gastrin release from G cells. It also plays a role in the regulation of cardiovascular function and neurotransmitter release. In addition, bombesin has been shown to stimulate the growth and proliferation of certain types of cancer cells, including prostate and lung cancer cells, through its interaction with bombesin receptors. It may therefore be used as a potential biomarker for certain cancers.
This product is available as a 0.5mg vial.

Fmoc-N-Amido-dPEG®3-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Fmoc-N-Amido-dPEG®3-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

MAL dPEG®6-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. MAL dPEG®6-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

This product has disulfide Bonds between Cys1-Cys15 and Cys3-Cys11, is sourced from: Porcine, 1-39 and is available as a 0.5mg vial. Big Endothelin-1 (Porcine, 1-39) is a precursor peptide of the vasoconstrictor Endothelin-1 (ET-1). ET-1 exhibits vasoconstrictive properties and is an activator of endothelin G-protein coupled receptors. Furthermore ET-1 is produced when inflammation, vascular stress or hypoxia occurs. In vivo Big Endothelin-1 has a greater half life compared to ET-1 and therefore makes it useful to study secretory activity in the endothelial system.
Overall Big Endothelin-1 (Porcine, 1-39) can be used as a research tool for studying protein interactions, receptor activation and function, and ligand binding. This peptide is also used in pharmacology to study the effects of therapeutic agents on receptor activity and expression.

Des-Arg9-[Leu8]-bradykinin is a bradykinin receptor activator. This peptide can be used as a research tool to study the relationship between peptides and ion channels in cell biology, and to assess the effects of inhibitors on protein interactions. Des-Arg9-[Leu8]-bradykinin has shown inhibitory activity against a number of ligand binding receptors, including the beta-adrenergic receptor, angiotensin II receptor, and acetylcholine muscarinic receptor. The affinity of this peptide for different receptors is dependent on its position within the molecule.

Gly-Phe-NH2 is an amino acid that can be used as a research tool in the study of protein interactions, receptor activation, and ion channels. It has been shown to activate ligands such as peptides and antibodies. This compound also inhibits ligands in the cell biology field. Gly-Phe-NH2• AcOH is a white powder with a purity of 99%.

m-dPEG®12-MAL is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®12-MAL is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

NPY (Human, Rat) is a peptide that belongs to the family of neuropeptides. It is a central neurotransmitter and neuromodulator in the brain and has an important role in the regulation of many physiological processes, including feeding behavior, body weight, blood pressure, stress responses and reproduction. NPY (Human, Rat) is used as a research tool for studying ion channels and receptor interactions. This product is also used to develop antibodies that can be used as a research tool or diagnostic reagent. NPY (Human, Rat) is not active when taken orally; it must be injected into the body.

Orexin-A (Human, 17-33) is a neuropeptide also known as hypocretin-1 and this product is available as a 0.1 mg vial. Orexin-A is primarily produced by a group of neurons located in the lateral hypothalamus of the brain, known as the orexinergic neurons.
Orexin-A is involved in regulating a variety of physiological functions, including the sleep-wake cycle, appetite, energy metabolism, and reward pathways. It acts as an agonist for two G protein-coupled receptors, known as orexin receptor 1 and orexin receptor 2.
Studies have shown that disruption of orexin signaling can lead to sleep disorders, obesity, and other metabolic disorders. Orexin-A has also been studied for its potential as a therapeutic target for the treatment of these disorders.

Amino-dPEG® t-Butyl Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Amino-dPEG® t-Butyl Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Arphamenine B is an enzyme inhibitor that inhibits metalloproteinases and serine proteases. It has been shown to be a potent osteoinductive agent in cell culture. Arphamenine B has also been found to have a depressant effect on the growth of cells in culture, with lysine residues as the probable site of action. Arphamenine B has also been shown to inhibit soybean trypsin, which is a serine protease enzyme.

Neuropeptide W-30 (Rat) is a peptide that belongs to the family of neuropeptides. It has been identified as an inhibitor of the ion channel TRPV1 and TRPA1, which are involved in pain perception. Neuropeptide W-30 (Rat) also inhibits the activation of phospholipase C, protein kinase C, and cAMP response element binding protein. Neuropeptide W-30 (Rat) is used as a research tool for studying protein interactions and for pharmacological studies.

Dnp-Pro-Gln-Gly is a synthetic peptide that can be used as an artificial substrate in protease assays. It is activated by the addition of trypsin and catalyzes hydrolysis of peptide bonds at the C-terminus of the proline residue. The chromatographic profile of Dnp-Pro-Gln-Gly on a Zorbax 300SBX column shows two peaks, with retention times of 8.2 minutes and 9.4 minutes. In tissue culture experiments, Dnp-Pro-Gln-Gly was found to enhance the activity of matrix metalloproteinases and collagenase. The optimum pH for Dnp-Pro-Gln-Gly is 5.5, which is near the pH optimum for most mammalian tissues and organs.

A synthetic voltage-dependent K+ channel blocker derived from bee venom. This product is sourced from the Honeybee, Apis mellifera and has disulfide bonds between Cys3-Cys15 and Cys5-Cys19.
Available as a 0.5mg vial.

Amino-dPEG®6-t-Butyl Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Amino-dPEG®6-t-Butyl Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Bis-dPEG®29-Acid is a PEG polymer categorised as homobifunctional PEG (X-PEG X). Used as a linker, bis-dPEG®29-Acid is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.

MAL-dPEG®4-t-boc-Hydrazide is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. MAL-dPEG®4-t-boc-Hydrazide is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

t-boc-N-Amido-dPEG®24-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. t-boc-N-Amido-dPEG®24-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Leu-pNA is a protein synthesis inhibitor that binds to the active site of the enzyme peptidyl prolyl cis-trans isomerase (PPIase). This inhibitor prevents the enzyme from catalyzing the conversion of proline residues in peptides to their cis or trans isomers. Leu-pNA has been shown to inhibit proteolytic enzymes such as soybean trypsin and activated proteases, and also has an inhibitory effect on polymerase chain reaction (PCR) enzyme activities. The binding of Leu-pNA to PPIase can be reversed by heating at 60°C for 20 minutes.

This product which is available as a 0.5mg vial is amino acids 1-31 of the 84 amino acid parathyroid hormone (PTH) and can be used as an adenylate cyclase and bone growth stimulating peptide.
PTH is a peptide hormone that is secreted from the parathyroid gland in the event of abnormal serum calcium levels and it ultimately regulates calcium and phosphate levels in the body. The PTH exerts its activity through binding to the G-protein coupled receptor type 1 PTH receptor, which activates adenylate cyclase or phospholipase C thus activating pathways involved in the mediation of bone resorption and bone formation. This product is suitable for life science applications.

Endothelin-1 is a peptide that acts as a vasoconstrictor and plays an important role in the regulation of blood pressure. Endothelin-1 is also an endogenous ligand for two G protein-coupled receptors, ETA and ETB. Interesting Endothelin-1 is the most abundant isoform and is expressed in endothelial cells of every blood vessel. It exerts its vasoconstrictor effects through binding to ETA receptors located on the smooth muscle. This product has disulfide bonds between Cys1-Cys15 and Cys3-Cys11, sourced from Porcine, Canine, Rat, Mouse and Bovine and is available as a 0.1mg vial.

GIP (Gastric Inhibitory Polypeptide) is a peptide hormone that belongs to the family of incretin hormones. GIP has been shown to have an insulinotropic effect, which is mediated by its activation of glucose-dependent insulin release from pancreatic β-cells. It also has effects on lipid metabolism and plays a role in the regulation of food intake. GIP is produced by K cells in the ileum and colon and released into the bloodstream following food intake. The binding of GIP to its receptors leads to inhibition of gastric acid secretion, stimulation of gallbladder contraction, increased blood flow to the stomach, relaxation of pyloric sphincter muscles, and inhibition of gastric motility. This product is highly pure (> 98%) with no detectable endotoxin or other microbial contamination.

Vasotocin is a peptide hormone that is found in the hypothalamus. It is an activator of the vasopressin receptor and has been shown to activate ion channels and inhibit the release of neurotransmitters. Vasotocin also binds to a specific receptor on the surface of cells, which may be involved in cell biology and may have applications in pharmacology and antibody research. Vasotocin is purified from pig pituitary glands.