Peptides

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SLC7A7 antibody, catalog no. 70R-6771</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PCDHA5 antibody, catalog no. 70R-6167</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of NINJ1 antibody, catalog no. 70R-6116</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of RUNDC2A antibody, catalog no. 20R-1267</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CYP1A1 antibody, catalog no. 70R-7256</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of MTR antibody, catalog no. 70R-5231</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of Urgcp antibody, catalog no. 70R-9383</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of UBXD2 antibody, catalog no. 20R-1265</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of LOC285033 antibody, catalog no. 70R-3365</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of GOLGA5 antibody, catalog no. 70R-6969</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of GEM antibody, catalog no. 70R-5974</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF700 antibody, catalog no. 70R-8989</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of FBXO36 antibody, catalog no. 70R-3784</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SFRS10 antibody, catalog no. 70R-1421</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CACNB3 antibody, catalog no. 70R-1512</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of BNIP1 antibody, catalog no. 70R-9800</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of KCNN4 antibody, catalog no. 70R-5153</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of Ercc1 antibody, catalog no. 70R-9364</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CCDC146 antibody, catalog no. 70R-4540</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of HIST1H2AE antibody, catalog no. 70R-10218</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of GTSE1 antibody, catalog no. 70R-5612</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of RFTN2 antibody, catalog no. 70R-4543</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of RDBP antibody, catalog no. 70R-4683</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of ATP4B antibody, catalog no. 70R-6951</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of LIG1 antibody, catalog no. 70R-5620</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of EIF4ENIF1 antibody, catalog no. 70R-3586</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PGM3 antibody, catalog no. 70R-4450</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CCND1 antibody, catalog no. 70R-7984</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of ACTR2 antibody, catalog no. 70R-1197</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of DDX3X antibody, catalog no. 70R-4688</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SLC35F3 antibody, catalog no. 70R-6807</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of C19orf24 antibody, catalog no. 70R-4955</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SERPINA5 antibody, catalog no. 70R-5417</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CTAG1B antibody, catalog no. 70R-10169</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of TH antibody, catalog no. 70R-7854</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of KIFC3 antibody, catalog no. 70R-5600</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PXT1 antibody, catalog no. 70R-4253</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of UGT2A3 antibody, catalog no. 70R-7206</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PPIE antibody, catalog no. 70R-1435</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of RPL18 antibody, catalog no. 70R-5007</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SLA/LP antibody, catalog no. 70R-4725</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of DDX27 antibody, catalog no. 70R-1385</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of AFAP1 antibody, catalog no. 70R-3533</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of HSPA9 antibody, catalog no. 70R-7827</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of NONO antibody, catalog no. 70R-1315</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of NRCAM antibody, catalog no. 70R-6388</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of TPTE antibody, catalog no. 70R-5655</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF266 antibody, catalog no. 70R-8084</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of KIF23 antibody, catalog no. 70R-5544</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CACNA1I antibody, catalog no. 70R-5133</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of HS3ST6 antibody, catalog no. 70R-2842</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of DNASE2B antibody, catalog no. 70R-5280</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PABPC1 antibody, catalog no. 70R-4653</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CD200R1 antibody, catalog no. 70R-9902</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of FZD9 antibody, catalog no. 70R-7131</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of RHBG antibody, catalog no. 70R-7321</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SLC9A1 antibody, catalog no. 70R-7268</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SCYL3 antibody, catalog no. 70R-3018</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of Bnip3l antibody, catalog no. 70R-9618</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of HPD antibody, catalog no. 70R-2553</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CBLL1 antibody, catalog no. 20R-1225</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of Uhmk1 antibody, catalog no. 70R-8494</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of TRIM17 antibody, catalog no. 20R-1091</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of MKNK1 antibody, catalog no. 70R-10043</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF364 antibody, catalog no. 70R-2797</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of HLA-F antibody, catalog no. 70R-6432</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of HSD3B1 antibody, catalog no. 70R-7092</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of AKR1C1 antibody, catalog no. 70R-10004</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of OR2W1 antibody, catalog no. 70R-9893</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of HSPB1 antibody, catalog no. 20R-1061</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of NTRK3 antibody, catalog no. 70R-7122</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of LOC653428 antibody, catalog no. 70R-9057</p>

<p>Peptide T is a synthetic peptide that has been shown to inhibit the activity of protein kinase C. This inhibition may be due to its ability to bind with high affinity and specificity to a site on the receptor protein. Peptide T is a research tool used in studies of cell biology, pharmacology, and physiology. It has been used as an inhibitor for studies of ion channels and has also been used as an activator for studies of receptor-ligand interactions. Peptide T is also known by its CAS number, which is P25657-1-2.</p>

<p>Z-Arg-OBzl(p-NO2) hydrobromide is a research peptide that is commonly used as an enzyme substrate in various biochemical studies. It is widely utilized in the field of molecular biology and biochemistry for its ability to mimic specific enzymatic reactions. This compound is highly pure and has been extensively tested for its quality and reliability. Researchers rely on Z-Arg-OBzl(p-NO2) hydrobromide to accurately measure enzyme activity and understand the mechanisms behind various biological processes. With its precise composition and consistent performance, this research peptide is an essential tool for scientists conducting cutting-edge research in the field.</p>

<p>Laminin is a structural protein that provides a scaffold for cell-cell and cell-matrix interactions. Laminin Pentapeptide YIGSR-NH2 is a synthetic peptide that has been shown to be an activator of the laminin receptor and an inhibitor of ion channels. It has also been used as a research tool in studies on antibody production, life science, cell biology, and pharmacology. This peptide is highly pure with no detectable contaminants.</p>

<p>A synthetic snake toxin, sourced from the black mamba, Dendroaspis polylepis and it is a ligand for Muscarinic Acetylcholine Receptor-3/5 (M3/M5) (non-specific ligand). This product is available as a 0.1mg vials and has disulfide bonds between  Cys3-Cys24, Cys17-Cys42, Cys46-Cys58, and Cys59-Cys64.</p>

<p>1-Deoxyfructosyl-Val-His (1DFVH) is a research tool that belongs to the group of activators. It has been shown to activate receptors and ion channels, as well as inhibit antibody production. 1DFVH also has an effect on cell biology, which may be due to its ability to interact with proteins in a variety of ways. 1DFVH binds to the receptor by competitive inhibition and activates the receptor by mimicking the natural ligand. This compound has been shown to activate ion channels in cells through the opening of potassium channels, leading to depolarization and increased calcium influx into cells.</p>

<p>Angiotensin III, human is a peptide hormone that acts as an important regulator of blood pressure and fluid balance. It binds to angiotensin receptors on vascular smooth muscle cells, which leads to vasoconstriction and an increase in the permeability of small blood vessels. Angiotensin III also stimulates the release of aldosterone from the adrenal gland, which leads to increased sodium retention and increased water reabsorption by the kidneys. Angiotensin III is used as a treatment for congestive heart failure and pulmonary edema. It has been shown to be effective in preventing myocardial infarction in animal models. The effects of Angiotensin III are mediated by its binding to specific receptors on the surface of cells, leading to changes in cell activity. These effects can be blocked with receptor antagonists such as losartan or valsartan.</p>

<p>Z-Gly-Pro-Leu-Gly is a synthetic peptide with a kinetic and biochemical profile that is similar to that of the bacterial enzyme monoiodotyrosine hydroxylase. Z-Gly-Pro-Leu-Gly has been shown to react with the substrate, monoiodotyrosine, by forming hydrogen bonds. The enzyme activities of Z-Gly-Pro-Leu-Gly are inhibited by neutral pH and increased at acidic pH. The optimum pH for this reaction is 4.5. When injected subcutaneously, Z-Gly-Pro-Leu-Gly can penetrate the skin and hydrolyze monoiodotyrosine in ascidians.</p>

<p>Anti-chromogranin A (344-374) is a peptide that binds to the receptor for gastrin. It is used as a research tool and can be used to study the pharmacology of gastrin and the role of this hormone in the regulation of stomach acid production. Anti-chromogranin A (344-374) is purified from human serum, with an antibody specific to the peptide immobilized on a solid support.</p>

<p>m-dPEG®8-Azide (Azido-m-dPEG®8) is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®8-Azide (Azido-m-dPEG®8) is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Blocker of P/Q-type calcium channel (Cav2.1)</p>

<p>ASIC1a/1b agonist</p>

<p>Slowing of Nav1.2, Nav1.4 and Nav1.7 channels' inactivation</p>

<p>Biotin-MAGE-A1 (278-286) is the N-ter biotinylated version of MAGE-A1 (278-286). Biotin-MAGE-A1 (278-286) can be used in the analysis of antigen-specific T cells. MAGE-A1 protein:<br>MAGE-A1 (278-286) is an epitope of Melanoma Antigen Gene A1 expressed by tumors of different histological types such as on the surface of breast carcinoma cell and is a Cancer/Testis Antigens (CTA). MAGE-A1 is a tumor antigen expressed in 40% of melanoma and contains epitope for binding HLA-A*02:01 molecules and that are recognized by cytotoxic T cells.<br>Applications of MAGE-A1 (278-286):<br>MAGE-A1 (278-286) is used to stimulate specific cytotoxic T cells in PBMCs and to analyze by ELISPOT peptide epitope specificity and cytokine production like IFN-γ. Immunogenicity of MAGE-A1 (278-286) raised the possibility of developing anticancer immunotherapies or vaccinations. MAGE-A1 is also expressed in lung adenocarcinoma and studies suggest that MAGE-A1 may serve to develop Chimeric Antigen Receptor (CAR) T cell therapy using lentiviral vector and show an encouraging tumor-inhibitory efficacy.<br>Sequence: Biotin-KVLEYVIKV</p>

<p>Cyclotide</p>

<p>Selective blocker of muscular nACh receptors</p>

<p>Human beta-defensin-2 (hBD-2), also known as skin-antimicrobial peptide 1 (SAP1) is a cysteine-rich cationic antimicrobial peptide of 41 amino acids. It was originally isolated from skin cells of psoriasis patients. hBD-2, which belongs to the defensin family, is implicated in the innate immunity thanks to its antimicrobial activity. Thus, β-defensins can play a role at the cutaneous level by limiting the use of antibiotics in severe burns and disease like psoriasis. Moreover, at the pulmonary level, defensins might be involved in the resorption of the infection in cases of cystic fibrosis.<br>hBD-2 is produced after stimulation of epithelial cells following their contact with some organisms like Gram-negative bacteria and Candida Albicans, fungus or cytokines such as TNF-alpha and IL-1 beta. This antimicrobial activity was shown to be microbicidal at concentrations greater than 1 µM and was lethal for E.Coli and pseudomonas (LD90 : 10 mg/mL) and Candida Albicans (LD90 : 25 mg/mL). Besides its antimicrobial activity, hBD-2 also exhibits proinflammatory properties as chemoattractants for memory T-cells, immature dendritic cells, mast cells and neutrophils.<br>hBD-2 has also demonstrated inhibitory activity of the voltage-gated potassium channel Kv1.3 at picomolar concentration. Kv1.3 are overexpressed by T-cells in case of autoimmune disorders.</p>

<p>Overlaping biotin-peptide library of Spike Omicron mutant. 15 amino acids per peptide with offset 11. Each peptide is N-ter biotinylated. Purity crude. 1 peptide per well.</p>

<p>Biotin-SARS-CoV-2 Spike RBM 480-496 (Biotin-LC) peptide is the biotinylated version of SARS-CoV-2 Spike RBM 480-496 peptide. SARS-CoV-2 Spike RBM 480-496 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Motif (RBM). Biotin-SARS-CoV-2 Spike RBM 480-496 peptide is useful for vaccine development and for structure-activity relationship studies<br>SARS-CoV-2 Spike (S) glycoprotein<br>Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells.<br>With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane.<br>SARS-CoV-2 Spike RBM:<br>The receptor-binding domain in SARS-CoV-2 Spike protein contains a receptor-binding motif RBM. SARS-CoV-2 Spike RBM is the main functional motif in RBD and allows contacts between the S protein and the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry.</p>

<p>TTX-S selective blocker</p>

<p>Protirelin – Thyrotropin-releasing hormone (TRH) (CAS: 24305-27-9)</p>

<p>SB-peptide offers the scrambled version of MAGE-A p248V9. RQYVELPYV can be used as a negative control of MAGE-A p248V9 studies.<br>SB-peptide offers also MAGE-A p248V9 (see section MAGE-A p248V9)).<br>MAGE-A protein:<br>MAGE-A p248V9, also kwon as multi-MAGE-A (YLEYRQVPV) is an epitope of Melanoma Antigen Gene expressed by tumors of different histological types and is a Cancer/Testis Antigens (CTA). Type of MAGE-A expressed in tumors cells varies according to the type of tumor. Targeting epitopes shared by all MAGE-A antigens would be interest in immunotherapy against a broad spectrum of cancers.<br>Applications of MAGE-A p248V9 (multi-MAGE-A) :<br>MAGE-A p248V9 is very useful because it could generate an HLA-A*02:01-restricted CTL response and shared by MAGE-A1,-A2,-A3,-A4,-A6,-A10 and -A12. MAGE-A p248V9 is used to stimulate specific cytotoxic T lymphocytes (CTL) in PBMCs and then to analyze CTL response especially the cytokine production by ELISPOT assay.<br>Sequence : RQYVELPYV</p>

<p>Hydrogels are a class of materials that are promising candidates for use in soft tissue and bone engineering. Hydrogels have a high water content, suitable viscoelasticity and biocompatibility.<br>Using hydrogel can help for biomedical applications such as tissue engineering, encapsulation methods for cells and biomolecules, drug delivery or some injectable delivery vehicles for therapeutics.<br>However, hydrogels are mainly used for their antimicrobial properties which are due to the surface of the hydrogel, having the capacity to disrupt negatively-charged bacterial membrane via electrostatic interactions. Antimicrobial activities of hydrogels were shown against gram-positive bacteria such as S.Aureus and gram-negative bacteria like E.Coli.<br>The main interest of employing hydrogels is its biocompatibility in vitro and in vivo which permits to hydrogel to be able to perform an appropriate host response in a specific situation.<br>It also seems that the antimicrobial peptide-based hydrogels are very effective against biofilm adhesion likely due to the physical mode of action involving bacterial membrane disruption.<br>Max 1 is the first MAX peptide described, a 20-amino acid peptide designed to understand peptide intramolecular folding. Max 1 is useful for making hydrogels owing to its ability to change its structural conformation according to environmental changes.<br>Max 1 stays unfolded and soluble in a low ionic strength aqueous solution (10 mM NaCl) at neutral pH however with a high salt concentration (150 mM NaCl) or a higher pH, Max 1 folds into an amphiphilic β-hairpin conformation that can self-assembles to form a network of fibrils that conducts to the formation of a hydrogel hairpin.</p>

<p>SB-peptide offers the scrambled version of MAGE-A2 (157-166). VLVYFQEIGL can be used as a negative control of MAGE-A2 (157-166) studies.<br>SB-peptide offers also MAGE-A2 (157-166) (see section MAGE-A2 (157-166)).<br>MAGE-A2 protein:<br>MAGE-A2 (157-166) is an epitope of Melanoma Antigen Gene A2 and is one of the most Cancer-Testis Antigens (CTA) overexpressed in tumors of different histological types, such as prostate cancer. Type of MAGE-A expressed in tumors cells varies according to the type of tumor. The expression of MAGE-A2 causes the proliferation of prostate cancer cells and decreases the chemosensitivity.<br>Applications of MAGE-A2 (157-166):<br>MAGE-A2 (157-166) is used to stimulate specific immune response, cytotoxic T cell response and to analyze the cytokine production in PBMCs by ELISPOT assay. In transgenic mouse, it has been demonstrated that MAGE-A2 (157-166) was capable of eliciting a CTL response presented by HLA-A*02:01 molecules. MAGE-A2 (157-166) has been reported to elicit CTL that could lyse tumor cell expressing both HLA-A*02:01 and MAGE-A2 by stimulation of peripheral blood mononuclear cells (PBMCs) with MAGE-A2 (157-166).<br>Sequence : VLVYFQEIGL</p>

<p>Selective blocker of N-type calcium channels</p>

<p>Selective blocker of Kv3.4 and potent Nav1.7 activator</p>

<p>SB-peptide offers the scrambled version of MAGE-A1 (278-286). ELIVKVYKV can be used as a negative control of MAGE-A1 (278-286) studies.<br>SB-peptide offers also MAGE-A1 (278-286) (see section MAGE-A1 (278-286)).<br>MAGE-A1 protein:<br>MAGE-A1 (278-286) is an epitope of Melanoma Antigen Gene A1 expressed by tumors of different histological types such as on the surface of breast carcinoma cell and is a Cancer/Testis Antigens (CTA). MAGE-A1 is a tumor antigen expressed in 40% of melanoma and contains epitope for binding HLA-A*02:01 molecules and that are recognized by cytotoxic T cells.<br>Applications of MAGE-A1 (278-286):<br>MAGE-A1 (278-286) is used to stimulate specific cytotoxic T cells in PBMCs and to analyze by ELISPOT peptide epitope specificity and cytokine production like IFN-γ. Immunogenicity of MAGE-A1 (278-286) raised the possibility of developing anticancer immunotherapies or vaccinations. MAGE-A1 is also expressed in lung adenocarcinoma and studies suggest that MAGE-A1 may serve to develop Chimeric Antigen Receptor (CAR) T cell therapy using lentiviral vector and show an encouraging tumor-inhibitory efficacy.<br>Sequence : ELIVKVYKV</p>

<p>APYTFGQGTK peptide is a sequence from light chain of Adalimumab monoclonal antibody. Due to its universal location in Adalimumab antibody, Stable Isotope Labeled (SIL) APYTFGQGTK is used as a specific signature peptide for the quantitation of Adalimumab.</p>

<p>α9α10 and α7 nAChRs channels discrimination</p>