Peptides

A synthetic peptide for use as a blocking control in assays to test for specificity of IL10RA antibody, catalog no. 70R-1865

A synthetic peptide for use as a blocking control in assays to test for specificity of MTRR antibody, catalog no. 70R-4020

A synthetic peptide for use as a blocking control in assays to test for specificity of ZDHHC24 antibody, catalog no. 70R-7007

A synthetic peptide for use as a blocking control in assays to test for specificity of LDLRAP1 antibody, catalog no. 70R-2837

Analog of the native Melan-A (26-35) decapeptide derives from the melanocyte lineage-specific protein Melan-A/MART-1, which is expressed in almost 75-100% of primary and metastatic melanomas.
The region 26-35 of Melan-A protein acts as an antigenic peptide that is recognized by CD8+ tumor-reactive cytolytic T lymphocytes (CTLs) for designing antigen-specific cancer vaccines1. It has been shown that CD8+ Melan-A-specific CTLs isolated from melanoma patients efficiently lyse the Melan-A-expressing HLA-A*0201+ melanoma cell line. However, CTLs preferentially recognize the Melan-A (26-35) peptide as compared with the Melan-A (27-35) peptide. Moreover, the Melan-A (26-35) A27L analog (ELAGIGILTV) has a higher binding affinity to HLA-A*0201 than the native Melan-A (26-35) peptide (EAAGIGILTV), and consequently displays more potent antigenicity and immunogenicity.
It has been reported that the concentration of Melan-A (26-35) A27L analog required to obtain 50% of maximal antigenic activity (EC50) is 0.01nM, whereas that of the native Melan-A (26-35) peptide is 0.25nM1. Therefore, the relative activity of Melan-A (26-35) A27L analog is 25 fold higher than that of the native Melan-A (26-35) peptide.
Furthermore, functional competition assay has shown that the concentration of Melan-A (26-35) A27L analog required to achieve 50% inhibition (IC50) of tumor lysis is 2nM, which is 10 fold lower than that of the native Melan-A (26-35) peptide. Regarding peptide stability in human serum, the half-lifes (t1/2) of the native Melan-A (26-35) peptide and the A27L analog are quite similar (45 and 40min, respectively) as measured by HPLC-ESI-MS, but much higher than that of the Melan-A (27-35) nonapeptide (5min).

A synthetic peptide for use as a blocking control in assays to test for specificity of DDX59 antibody, catalog no. 70R-4735

A synthetic peptide for use as a blocking control in assays to test for specificity of CYP2R1 antibody, catalog no. 70R-8833

A synthetic peptide for use as a blocking control in assays to test for specificity of LOC390338 antibody, catalog no. 70R-8037

A synthetic peptide for use as a blocking control in assays to test for specificity of Ppp2r2d antibody, catalog no. 70R-9373

A synthetic peptide for use as a blocking control in assays to test for specificity of OR2C3 antibody, catalog no. 70R-9859

A synthetic peptide for use as a blocking control in assays to test for specificity of SPATA7 antibody, catalog no. 70R-4374

A synthetic peptide for use as a blocking control in assays to test for specificity of MSL3L2 antibody, catalog no. 70R-9064

A synthetic peptide for use as a blocking control in assays to test for specificity of UBQLN3 antibody, catalog no. 70R-2645

A synthetic peptide for use as a blocking control in assays to test for specificity of ACSL3 antibody, catalog no. 70R-6570

A synthetic peptide for use as a blocking control in assays to test for specificity of C8orf45 antibody, catalog no. 70R-9222

A synthetic peptide for use as a blocking control in assays to test for specificity of CD55 antibody, catalog no. 70R-10001

A synthetic peptide for use as a blocking control in assays to test for specificity of CRMP1 antibody, catalog no. 70R-5252

A synthetic peptide for use as a blocking control in assays to test for specificity of RHBDL2 antibody, catalog no. 70R-6880

A synthetic peptide for use as a blocking control in assays to test for specificity of LRRTM4 antibody, catalog no. 70R-7442

A synthetic peptide for use as a blocking control in assays to test for specificity of ZADH2 antibody, catalog no. 70R-3404

A synthetic peptide for use as a blocking control in assays to test for specificity of C11orf16 antibody, catalog no. 70R-9501

A synthetic peptide for use as a blocking control in assays to test for specificity of MLSTD2 antibody, catalog no. 70R-1829

A synthetic peptide for use as a blocking control in assays to test for specificity of ZFP287 antibody, catalog no. 20R-1161

A synthetic peptide for use as a blocking control in assays to test for specificity of E2F3 antibody, catalog no. 70R-8240

A synthetic peptide for use as a blocking control in assays to test for specificity of FSTL5 antibody, catalog no. 70R-1991

A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF708 antibody, catalog no. 70R-8963

A synthetic peptide for use as a blocking control in assays to test for specificity of CHERP antibody, catalog no. 70R-5262

The Nucleocapsid Protein (N-protein), also called coronavirus nucleocapsid (N), is the most abundant protein in coronavirus. It is a structural protein that forms complexes with genomic RNA, interacts with the viral membrane protein during virion assembly and plays a critical role in enhancing the efficiency of virus transcription and assembly.

Fmoc-N-Amido-dPEG®24-TFP Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Fmoc-N-Amido-dPEG®24-TFP Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

SARS Coronavirus is an enveloped virus containing 3 outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein takes part in the virus infection cycle and is the primary target of neutralizing antibodies. The recombinant SARS Spike containing a total of 220 amino acids (306-515) and having a calculated M.W. of 24.8 kDa.SARS Spike  is fused to a 6 amino acid His-tag at C-terminus, and is purified by proprietary chromatographic techniques. Of a HEK293 source the formulation of the SARS Spike (306-515) solution (0.5mg/ml) contains Phosphate-Buffered Saline (pH 7.4) and 10% Glycerol.
One-Letter Formula: DGSMRVVPSG DVVRFPNITN LCPFGEVFNA TKFPSVYAWE RKKISNCVAD YSVLYNSTFF STFKCYGVSA TKLNDLCFSN VYADSFVVKG DDVRQIAPGQ TGVIADYNYK LPDDFMGCVL AWNTRNIDAT STGNYNYKYR YLRHGKLRPF ERDISNVPFS PDGKPCTPPA LNCYWPLNDY GFYTTTGIGY QPYRVVVLSF ELLNAPATVC GPKLHHHHHH

A synthetic peptide for use as a blocking control in assays to test for specificity of Bapx1 antibody, catalog no. 70R-8191

A synthetic peptide for use as a blocking control in assays to test for specificity of ARV1 antibody, catalog no. 70R-6453

A synthetic peptide for use as a blocking control in assays to test for specificity of Lgi2 antibody, catalog no. 70R-8683

A synthetic peptide for use as a blocking control in assays to test for specificity of WNT1 antibody, catalog no. 70R-7124

A synthetic peptide for use as a blocking control in assays to test for specificity of RNF212 antibody, catalog no. 70R-2823

A synthetic peptide for use as a blocking control in assays to test for specificity of ACAD9 antibody, catalog no. 70R-10179

A synthetic peptide for use as a blocking control in assays to test for specificity of CDKL2 antibody, catalog no. 70R-3300

A synthetic peptide for use as a blocking control in assays to test for specificity of LRRC24 antibody, catalog no. 70R-6429

A synthetic peptide for use as a blocking control in assays to test for specificity of RASGRF1 antibody, catalog no. 70R-5816

A synthetic peptide for use as a blocking control in assays to test for specificity of CLEC4M antibody, catalog no. 70R-1704

A synthetic peptide for use as a blocking control in assays to test for specificity of Ctsd antibody, catalog no. 70R-8506

A synthetic peptide for use as a blocking control in assays to test for specificity of Hps3 antibody, catalog no. 70R-7822

Sarafotoxin S6b, sourced from the venom of the Atractaspis engaddensis snake family, is one of four (S6a-d) isopeptides of the Sarafotoxins. This product is a synthetically produced toxin, containing disulfide bonds between Cys1-Cys15 and Cys3-Cys11.Due to their structural and functional homology to the endothelin peptides, Sarafotoxins can enhance vasoconstriction through stimulating the class A G-protein-coupled, endothelin ETA and ETB receptors. This in turn leads to left ventricular dysfunction and bronchoconstriction.
As the most potent Sarafotoxin, sarafotoxin S6b binds to both ETA and ETB receptors with a similar affinity to Endothelin-1. This is evident as when given to mice intravenously, sarafotoxin S6b caused cardiac arrest and death in mice almost immediately. Additional characteristics of S6b is its matrix metalloproteinase inhibitory activity due to it exhibiting a fold which is also found in the core region of tissue inhibitors of metalloproteinases (TIMPs).
Sarafotoxin S6b can be used as a pharmacological reagent to study the interactions of Endothelins and their corresponding receptors. This product is available as a 0.1mg vial.

A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF605 antibody, catalog no. 20R-1121

A synthetic peptide for use as a blocking control in assays to test for specificity of CHST1 antibody, catalog no. 70R-1892

A synthetic peptide for use as a blocking control in assays to test for specificity of KCNK12 antibody, catalog no. 70R-5130

A synthetic peptide for use as a blocking control in assays to test for specificity of LANCL2 antibody, catalog no. 70R-2713

A synthetic peptide for use as a blocking control in assays to test for specificity of CCNB3 antibody, catalog no. 70R-8395

A synthetic peptide for use as a blocking control in assays to test for specificity of C9orf4 antibody, catalog no. 70R-6869

A synthetic peptide for use as a blocking control in assays to test for specificity of JAZF1 antibody, catalog no. 70R-8162

A synthetic peptide for use as a blocking control in assays to test for specificity of SUSD4 antibody, catalog no. 70R-6884

A synthetic peptide for use as a blocking control in assays to test for specificity of GH2 antibody, catalog no. 70R-1713

A synthetic peptide for use as a blocking control in assays to test for specificity of PGBD3 antibody, catalog no. 70R-1365

A synthetic peptide for use as a blocking control in assays to test for specificity of MAGEA9 antibody, catalog no. 70R-8268

A synthetic peptide for use as a blocking control in assays to test for specificity of UCHL1 antibody, catalog no. 70R-9725

A synthetic peptide for use as a blocking control in assays to test for specificity of OR13C9 antibody, catalog no. 20R-1072

A synthetic peptide for use as a blocking control in assays to test for specificity of ADORA2A antibody, catalog no. 70R-9945

A synthetic peptide for use as a blocking control in assays to test for specificity of LONRF3 antibody, catalog no. 70R-2808

A synthetic peptide for use as a blocking control in assays to test for specificity of NES antibody, catalog no. 70R-5230

Selective blocker of Kv3.4 and potent Nav1.7 activator

A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF555 antibody, catalog no. 70R-8141

A synthetic peptide for use as a blocking control in assays to test for specificity of ACCN4 antibody, catalog no. 70R-5078

A synthetic peptide for use as a blocking control in assays to test for specificity of NKX2-4 antibody, catalog no. 70R-8202

A synthetic peptide for use as a blocking control in assays to test for specificity of DHRS2 antibody, catalog no. 70R-8533

A synthetic peptide for use as a blocking control in assays to test for specificity of PLS3 antibody, catalog no. 70R-3756

A synthetic peptide for use as a blocking control in assays to test for specificity of SIN3A antibody, catalog no. 70R-7928

A synthetic peptide for use as a blocking control in assays to test for specificity of BBS4 antibody, catalog no. 70R-4576

A synthetic peptide for use as a blocking control in assays to test for specificity of CDR2L antibody, catalog no. 70R-8310

A synthetic peptide for use as a blocking control in assays to test for specificity of SMR3A antibody, catalog no. 70R-5435

A synthetic peptide for use as a blocking control in assays to test for specificity of PDLIM3 antibody, catalog no. 70R-2995

Custom research peptide; min purity 95%.

A synthetic peptide for use as a blocking control in assays to test for specificity of KLHDC8A antibody, catalog no. 70R-4854

Amino-dPEG®8-t-boc-hydrazide is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Amino-dPEG®8-t-boc-hydrazide is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

A synthetic peptide for use as a blocking control in assays to test for specificity of FBXO25 antibody, catalog no. 70R-2788

A synthetic peptide for use as a blocking control in assays to test for specificity of SOX17 antibody, catalog no. 70R-7976

Amino-dPEG®2-t-Butyl Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Amino-dPEG®2-t-Butyl Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Angiotensin (human, 1-7) is a peptide that acts as an agonist for the angiotensin II receptor. It is used in research as a pharmacological tool and in cell biology to study protein interactions and signaling pathways. It is also used to study the role of angiotensin receptors in various diseases such as hypertension and heart disease. Angiotensin (human, 1-7) is supplied at high purity and without any contaminants.

A synthetic peptide for use as a blocking control in assays to test for specificity of C5orf24 antibody, catalog no. 70R-1981

A synthetic peptide for use as a blocking control in assays to test for specificity of Sesn1 antibody, catalog no. 70R-9301

A synthetic peptide for use as a blocking control in assays to test for specificity of KLHL5 antibody, catalog no. 20R-1097

A synthetic peptide for use as a blocking control in assays to test for specificity of MGAT2 antibody, catalog no. 70R-7297

A synthetic peptide for use as a blocking control in assays to test for specificity of TMPRSS5 antibody, catalog no. 70R-6998

A synthetic peptide for use as a blocking control in assays to test for specificity of SPZ1 antibody, catalog no. 20R-1158

A synthetic peptide for use as a blocking control in assays to test for specificity of LAX1 antibody, catalog no. 70R-6590

A synthetic peptide for use as a blocking control in assays to test for specificity of TAPBP antibody, catalog no. 70R-6000

A synthetic peptide for use as a blocking control in assays to test for specificity of Pnrc2 antibody, catalog no. 70R-9468

A synthetic peptide for use as a blocking control in assays to test for specificity of HS3ST5 antibody, catalog no. 70R-7454

A synthetic voltage-dependent K+ channel blocker derived from bee venom. This product is sourced from the Honeybee, Apis mellifera and has disulfide bonds between Cys3-Cys15 and Cys5-Cys19.
Available as a 0.5mg vial.

A synthetic peptide for use as a blocking control in assays to test for specificity of RFC3 antibody, catalog no. 70R-5527

A synthetic peptide for use as a blocking control in assays to test for specificity of Wnt10a antibody, catalog no. 70R-8497

A synthetic peptide for use as a blocking control in assays to test for specificity of FUNDC1 antibody, catalog no. 70R-3364

A synthetic peptide for use as a blocking control in assays to test for specificity of DOK5 antibody, catalog no. 70R-3341

A synthetic peptide for use as a blocking control in assays to test for specificity of MOGAT1 antibody, catalog no. 70R-6677

A synthetic peptide for use as a blocking control in assays to test for specificity of NRP1 antibody, catalog no. 70R-9671

A synthetic peptide for use as a blocking control in assays to test for specificity of CUEDC1 antibody, catalog no. 70R-1277