Peptides

<p>Peptide H-THFPQFSYSASIR^E-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-AAVYHHFISDGVR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-QQFFGLM-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Peptide Ac-CAF-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Peptide H-DAAQK^TDTSHHDQDHPTF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide β-Neo-Endorphin is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

<p>Peptide H-VEHWGL^DEPL^LK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>PTH is a peptide hormone that is secreted from the parathyroid gland in the event of abnormal serum calcium levels and it ultimately regulates calcium and phosphate levels in the body. The PTH exerts its activity through binding to the G-protein coupled receptor type 1 PTH receptor, which activates adenylate cyclase or phospholipase C thus activating pathways involved in the mediation of bone resorption and bone formation. This product is suitable for life science applications and is available as a 20µg vial.</p>

<p>Peptide H-K^VL^EHVVRV-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Peptide H-WLGLSAEYGNLYR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>H-[Cys-Arg-Gly-Asp-Lys-Gly-Pro-Asp-Cys]-NH2 is a peptide that was originally isolated from the venom of the Brazilian spider, Phoneutria nigriventer. This peptide has been shown to have anti tumor activity in mice by targeting and binding to the tumor cells. H-[Cys-Arg-Gly-Asp-Lys-Gly-Pro-Asp-Cys]-NH2 is also a cell penetrating peptide (CPP) that can penetrate into the cell and disrupts cancer cell growth. It is also a disulfide rich peptide with RGD sequence which binds to integrins on the surface of tumor cells and induces apoptosis.</p>

<p>H-Lys(Boc)-2-ClTrt-Resin (100-200 mesh) 1% DVB is a building block that can be used for the synthesis of peptides. It is an amine resin that contains two reactive groups, one thiol and one amine. H-Lys(Boc)-2-ClTrt-Resin (100-200 mesh) 1% DVB is also a building block for alcohols and thiols.</p>

<p>Fmoc-Gly-Wang Resin is a high purity resin that is used as an inhibitor in peptide synthesis. It is supplied at a 1% DVB content. This resin has been used in the synthesis of many biologically active peptides, including vasopressin and oxytocin. Fmoc-Gly-Wang Resin is also used for receptor binding studies, antibody production and ion channel research.</p>

<p>TentaGel is a gelatinous resin, an important support for solid phase synthesis. TentaGel resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol) as shown below. The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix. The TentaGel S base resins are available with several different derivative choices. The typical capacity range for our TentaGel base resins is 0.2-0.3 meq/g.<br>Application: (90 µm)<br>Substitution Functional Group: -O-CH2-CH2-NH2</p>

Peptide H-LSEPAELTDAVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

H-Arg-Arg-Leu-Ile-Glu-Asp-Ala-Glu-Tyr(H2PO3)-Ala-Ala-Arg-Gly-NH2 is a peptide with a molecular weight of 5,879 Da. It has an active form that is phosphorylated on tyrosine at the 20th amino acid position and dephosphorylated at the 22nd amino acid position.

<p>Derivatizable Cell-Penetrating Peptide (CPP) for Click Chemistry. Can be applied as a Cys- Activated TAT for Cargo Conjunction. This product is available in the salt form: Trifluoroacetate Salt</p>

<p>Peptide H-KLVVVGADGV^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Peptide Biot-PPAHGVTSAPDTRPA-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Peptide H-YSSLAEAASK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-VTVAGLAGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-VPQTPLHTSR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>IL-1 beta is a cytokine that plays an important role in the inflammatory response. IL-1 beta is produced by macrophages, monocytes, and fibroblasts in response to stimuli such as lipopolysaccharide (LPS), bacterial endotoxin, and other cytokines. It is also produced by keratinocytes and dendritic cells in response to bacterial products. IL-1 beta binds to the IL-1 receptor on the cell surface membrane, triggering a cascade of reactions inside the cell that lead to changes in gene expression and protein production. IL-1 beta can be used as an indicator of inflammation due to its release by activated lymphocytes, natural killer cells, and neutrophils during acute infections. The presence of this substance indicates that there has been tissue damage or some other form of cell injury.</p>

<p>Myelin PLP (178-191) is a peptide that is immunogenic. It is useful for the study of myelin protein and its role in the human body. It can be used for various purposes, such as studying the effects of myelin protein on the immune system or how it is involved in neural transmission.</p>

Peptide H-LVVVGACGVGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Cyclorasin 9A54 is a peptide that is a potent activator of the G protein-coupled receptor, CXCR4. Cyclorasin 9A54 is a ligand that binds to the CXCR4 receptor and activates its signaling pathway by binding to the receptor and activating it. Cyclorasin 9A54 has been shown to inhibit the activity of ion channels in cells with high purity, as well as to be an antibody for cell biology research.</p>

<p>For use in peptide synthesis; particle size: 90 µm capacity: 0.18 - 0.22 mmol/g</p>

<p>The myelin sheath which is located in both the Central Nervous System (CNS) and the Peripheral Nervous System is crucial for neural insulation and the salutatory conduction of nerve impulses. When this myelin sheath is destroyed neurodegeneration and conduction failure occur and theses occurrences can be observed in demyelinating diseases in the CNS such as: acute disseminated encephalomyelitis and multiple sclerosis and within the PNS: Guillain–Barré syndrome and Charcot–Marie–Tooth disease.<br>Myelin Basic Protein (MBP) from which this product is derived is the second most abundant protein in myelin. It has been found to be an intrinsically disordered protein and depending on the environmental conditions it can change its conformation. It also folds into ⍺-helical structures which allow MBP to bind tightly to lipid bilayer surfaces. MBP also interacts with other proteins, namely cytoskeletal proteins and calmodulin and may be involved in signalling pathways.<br>Although more research needs to be carried out, it is thought that MBP significantly contribute to the pathogenesis of multiple sclerosis. As MBP is an autoantigen it can be recognized and cleaved by autoantibodies and is a substrate for the immunoproteasome. Additional research has found that post-translational modifications of MBP such as the removal of arginine are increased and may be involved in the pathogenesis of multiple sclerosis. Therefore this protein derived from MBP can be used to mimic Neurodegenerative disease phenotypes in research and animal models.</p>

BQ-788 is a sodium salt that has high resistance to corrosion. It is effective in wastewater treatment, as it can be used as a coagulant and flocculant. BQ-788 is an electrochemical impedance spectroscopy (EIS) active ingredient that has been shown to have good thermodynamic data. This chemical substance also displays optimum concentration at 6 mM in sulfuric acid and crystalline cellulose, with a solubility of 2.5% at room temperature. The EIS measurements were performed on the locomotor activity of rats with metabolic disorders, which led to the conclusion that BQ-788 is an important factor for locomotor activity through its effects on the central nervous system and peripheral nervous system.

<p>For preparation of acids, alcohols, thiols, or amines</p>

<p>Peptide Ac-GYAGTLQSL-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Peptide Ac-TARKSTGGC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Peptide 5Fam-VLQWAEKGYYTMSNN-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Peptide H-GWVTDGFSSL^K-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Nesfatin-1 Like Peptide (Mouse) is a peptide that regulates feeding behavior and insulin secretion. It is an insulinotropic peptide, which means it stimulates the release of insulin from pancreatic beta cells. Nesfatin-1 Like Peptide (Mouse) has been shown to be upregulated in the hypothalamus during fasting, thereby regulating feeding behavior. This peptide also has neurologic effects, such as stimulating locomotor activity, and may have antiinflammatory effects.</p>

<p>Fmoc-Ile-Rink-Amide MBHA Resin is a resin that is used in the synthesis of peptides. It is composed of amino acid building blocks, which are connected to form polymers. The resin is insoluble in water and organic solvents, which makes it suitable for use in peptide synthesis and other applications. Fmoc-Ile-Rink-Amide MBHA Resin can be used as an alternative to polystyrene and polypropylene resins because it has a higher loading capacity and is more stable at high temperatures.</p>

Peptide H-DR^VYIHPFHL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>H-Met-2-ClTrt-Resin (100-200 mesh) 1% DVB is a resin for peptide synthesis. It is a new, high yielding building block for the production of peptides by solid phase synthesis. The resin can be used as a building block for the synthesis of amines, alcohols, and thiols.</p>

Boc-Gln-Ala-Arg-AMC is a peptide inhibitor of the human voltage-gated potassium channel Kv1.2. It is a competitive antagonist of the Kv1.2 channel and has been shown to inhibit the proliferation of human cancer cells in vitro and in vivo. Boc-Gln-Ala-Arg-AMC binds to the S4 segment of Kv1.2, which is located on the surface of the channel. This binding prevents opening of the voltage sensor domain and thereby reduces or eliminates current flow through the channel. Boc-Gln-Ala-Arg-AMC can be used as a research tool for studying protein interactions with ion channels, as well as for understanding receptor activation mechanisms and ligand binding sites.

<p>Boc-Glu-Lys-Lys-AMC is a research tool that can be used to study protein interactions. It can also be used as an inhibitor in pharmaceuticals to reduce the risk of adverse effects. This product has high purity and is a peptide that is labeled with an amino acid. Boc-Glu-Lys-Lys-AMC is a small molecule that binds to receptors on cells, altering ion channels and cell communication. It may also bind to antibodies or ligands, preventing binding of these molecules to their receptor sites. Boc-Glu-Lys-Lys-AMC has CAS number 73554-85-5.</p>

<p>Peptide H-DFDFVPPVVR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-YLIPNATQPESK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Fmoc-Asp(Edans)-OH is a Building Block that is used in peptide synthesis. It is a fluorescent amino acid and can be used as a building block for creating fluorescein-labeled peptides. This product is also sold as a Building Block for use in peptide synthesis, which can be used to produce fluorescently labeled peptides.</p>

<p>Peptide H-WRWYCR-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

MOCAc-Gly-Ser-Pro-Ala-Phe-Leu-Ala-Lys(Dnp)-D-Arg is a peptide that is used as an activator and inhibitor of ion channels. This peptide has been shown to be a potent inhibitor of the voltage dependent Na+ channel, which is responsible for the depolarization of nerve and muscle cells. MOCAc has also been shown to bind with high affinity to the NMDAR receptor in a competitive manner. The binding of this peptide to the NMDAR receptor prevents glutamate from binding, which leads to inhibition of downstream signaling pathways such as NMDA receptor activation and intracellular calcium release.

<p>Bz-Arg-His-D-Asp-CH2Cl is a research tool that can be used as an activator or ligand in cell biology and pharmacology. This product is also a receptor, which is a protein that binds to one or more specific substances (ligands) and triggers a change in the activity of cells. Receptors are often located on the surface of cells, such as those in the brain, heart and muscles. Bz-Arg-His-D-Asp-CH2Cl can be used to inhibit ion channels and has been shown to block receptors for acetylcholine, histamine and serotonin. Bz-Arg-His-D-Asp-CH2Cl also blocks calcium channels and potassium channels. This product has been shown to inhibit the activity of phospholipase A2, which helps break down fats into fatty acids. It also inhibits the activity of aminopeptidases, which breaks down proteins into</p>

Boc-Val-Leu-Lys-AMC is a research tool that has been shown to activate ion channels and increase the permeability of cell membranes. This compound also binds to receptors on cells, which may be due to its ability to bind with antibodies. Boc-Val-Leu-Lys-AMC has been used as an inhibitor in protein interactions and pharmacology studies, as well as for the study of ion channels in cell biology.

<p>Biotinoylsarcosine is a synthetic compound that is used in biotechnology as a building block for the production of biotin-conjugated proteins and peptides. Biotinoylsarcosine has been shown to bind to human serum albumin with high affinity, which may be due to its carboxylate functionalities. This chemical can also be conjugated with other molecules through multistep reactions, simplifying the process of creating biotin-conjugated compounds. Biotinoylsarcosine is deactivated by biotinidase enzymes and used as a pretargeting agent in positron emission tomography imaging studies. Streptavidin, an avidin protein, can bind this compound with high affinity and has been used in biochemical studies as a tool for peptide synthesis.</p>

<p>Leupeptin is an ion channel blocker that belongs to the group of protease inhibitors. It blocks the passage of ions across cell membranes by binding to the active site of a variety of enzymes in the membrane. Leupeptin is used as a research tool for studying protein interactions, and can be used for antibody production. Leupeptin is also useful in cell biology studies, because it inhibits the activation of many proteins involved in signal transduction and cell division.</p>

Chloromethylated Polystyrene Resin (200-400 mesh) 1% DVB is a reaction solution that is used in biological studies. It reacts with human serum to form a bicyclic heterocycle. The hydrogen fluoride in the reaction solution reacts with the trifluoroacetic acid to form an intermediate, which then reacts with the chloromethylated polystyrene resin to form the bicyclic heterocycle. The redox potentials of this reaction are measured and can be used as a probe for determining the chemical stability of this product. This product has been shown to have fluorescence properties and can be used as a probe for detecting DNA and RNA samples in vitro.

<p>Boc-D-Ala-OH is a chiral amino acid that can be used in the synthesis of peptides. Boc-D-Ala-OH is a building block for the synthesis of amino acids, and it can also be used as a ligand to form metal complexes. This product has been shown to be effective in reducing optical activity through chemoenzymatic reduction processes. Boc-D-Ala-OH has also been shown to be hydrolyzed by various enzymes, including alcohols and acrylates.</p>

<p>Peptide H-ASGQAFELILSPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Prolyl Endopeptidase is a polypeptide that belongs to the family of enzymes known as endopeptidases. It is involved in peptide degradation and has been shown to be inhibited by synthetic products. Prolyl Endopeptidase is structurally similar to other members of the serine protease family and has been shown to hydrolyze the polypeptide bond adjacent to proline residues.</p>

<p>Z-Val-Lys-Met-MCA is a synthetic peptide that can act as an inhibitor or activator. Z-Val-Lys-Met-MCA binds to the receptor and inhibits the receptor from binding with its ligand, which prevents activation of the receptor. It also has been shown to activate other receptors, such as ion channels, by binding to them. This makes it an important research tool for understanding protein interactions.</p>

<p>Boc-p-Aminobenzoic Acid is an extracellular peptidase inhibitor that has been shown to be damaging to cells. It is a conjugate of p-aminobenzoic acid with the unusual amino acid Boc, which inhibits the activity of proteinases and peptidases. This drug is used for the treatment of emphysema, an autoimmune disease, and prostate carcinoma. It has also been shown to inhibit the growth of some tumor cells by blocking cell division and DNA synthesis. The enzyme carbonic anhydrase II (CAII) is responsible for the conversion of carbon dioxide into bicarbonate ions in tissues. Boc-p-Aminobenzoic Acid can inhibit CAII, which may lead to tissue damage or death.</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Boc-Phe-OH is a group P2, amide compound. It has been shown to exhibit anti-cancer activity and has been used in the synthesis of peptides. Boc-Phe-OH is an inhibitor of aminopeptidases and has been shown to inhibit the growth of herpes simplex virus. As a result, it is a useful tool for studying the biological function of these enzymes.</p>

<p>Octreotide is a drug that belongs to the macrocycle class of polymers. It is used in the treatment of cancer, as well as for diseases such as diabetes mellitus and acromegaly. Octreotide has been shown to inhibit p-glycoprotein (P-gp) and other drug transporters, which leads to an increase in oral bioavailability. In addition, octreotide also inhibits cellular proliferation by interfering with intracellular signalling pathways and protein synthesis. This drug has been shown to have a wide range of biochemical properties and is being investigated as an investigational agent for the treatment of various cancers.</p>

<p>Boc-Cys(Acm)-OH is a peptide that is used as a research tool in cell biology. It can be used to activate an antibody and is frequently used in studies of ion channels. Boc-Cys(Acm)-OH binds to the receptor, which leads to the activation of ligand binding, leading to pharmacological activity. The chemical formula for this compound is C24H38N6O7 with a molecular weight of 498.09 g/mol.</p>

<p>Amastatin is a synthetic product that inhibits peptidases. It is an inhibitor of the protease enzyme and can be used in the treatment of bladder infections caused by Chlamydia parvum. Amastatin has also been shown to inhibit Aminopeptidase, which is an enzyme that cleaves amino acids from proteins, thereby inhibiting protein synthesis. Amastatin has been shown to have an inhibitory effect on proteases in the striatal membranes of rats and may be useful in treating neurodegenerative disorders such as Parkinson's disease.</p>

<p>Enkephalins are a group of endogenous peptides that are the most potent natural analgesic and have been shown to relieve pain by inhibiting neurotransmitters. The (Met(O)5)-enkephalin analog is a structural analog of the enkephalin peptide with a sulfoxide linkage at position 5. This analog has been shown to inhibit acetylcholine release from intestinal ganglia, which may be related to its effects on postsynaptic potentials and glutamate release. This compound also absorbs in the small intestine, where it is taken into the blood stream and transported to the brain. The (Met(O)5)-enkephalin analog has been shown to reduce pain in Sprague-Dawley rats, as well as inhibit intestinal transit time and stimulate intestinal motility.</p>

<p>Boc-D-Trp-OH is a trisubstituted, enantiomerically pure, excitatory amino acid. It has been shown to stimulate the release of neurotransmitters in the central nervous system and to have potent antitumor activity. Boc-D-Trp-OH is an unsaturated ketone that can be used as a building block for peptide synthesis. The disulfide bond present in this molecule may be reduced by the addition of DTT or DTE. This compound has also been shown to have cardiac hypertrophy inhibiting effects, due to its ability to inhibit PDE5 enzyme activity.</p>

<p>Peptide ADSA-CFTR is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Fmoc-Pro-OH is a peptide that contains the Fmoc protecting group. It is used in the synthesis of peptides and has been shown to be effective against microbial infections with marine sponges. The synthesis of this compound can be carried out on an on-line automated peptide synthesizer. The Fmoc protecting group is removed by treatment with trifluoroacetic acid (TFA) in dichloromethane, which leaves the side chain unprotected. This compound has a high binding affinity for the receptor site of fibrinogen and can potentially inhibit the growth of bacteria that cause bacterial infection, such as Staphylococcus aureus and Pseudomonas aeruginosa.<br>Fmoc-Pro-OH can also be used to synthesize other functional groups such as sulfamoyl groups or acetonitrile groups, depending on the desired outcome.</p>

<p>Haptens are small-molecule drugs that bind to the toll-like receptor. Haptens can be used as a vaccine adjuvant and have been shown to be effective in the prevention of pandemic influenza. Haptens also inhibit viral replication by binding to surface glycoproteins, which prevents them from attaching to host cells. This process triggers the production of reactive oxygen species (ROS) and other inflammatory cytokines, which ultimately result in significant cytotoxicity. Haptens are capable of transferring immune responses from one animal to another, but this transfer is not always successful due to the basic protein structure of haptens.</p>

<p>CA-074 is a research tool that can be used to study protein interactions. CA-074 is a small, synthetic peptide and a potent inhibitor of the ion channel TRPC1. It has been shown to inhibit the calcium currents in HEK293 cells expressing TRPC1 channels. CA-074 inhibits the kinase activity of PLCγ2, which leads to reduced phosphoinositide levels and a decrease in cell proliferation. CA-074 also inhibits PKCδ and PKCε, which are members of the protein kinase C family.<br>The inhibition of these enzymes by CA-074 causes an increase in the intracellular concentration of diacylglycerol (DAG) and inositol triphosphate (IP3). These two molecules are involved in G protein signaling pathways that regulate cell proliferation, differentiation, and survival.</p>

<p>A prototype fluorogenic substrate targeting the SARS-CoV and SARS-CoV-2 Main Protease (Mpro). The main protease (Mpro­), also called endopeptidase C30 or 3C-like proteinase (3CLpro), controls viral replication activities and is a prime therapeutical target. Both substrates and inhibitors of SARS-CoV-2 Mpro are currently of interest to researchers of the coronavirus. This product can be used as a Prototype Fluorescence Substrate for SARS-CoV Mpro/SARS-CoV-2 Mpro Proteases.</p>

Peptide Ac-DESDFGPLVGADS-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Peptide H-GNDISSGTVLSDYVGSGPPK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>PAMP (human) is a peptide that binds to the G-protein coupled receptor, M3. It activates the ion channel and induces an influx of calcium ions into cells. This can lead to cell proliferation and differentiation, as well as increased blood flow in the brain. PAMP has been shown to inhibit ligand-induced activation of M3 receptors by competing with the natural ligands for binding sites on these receptors. It has also been shown to have high purity (&gt;95%), and is currently under research for its use in various medical applications such as cancer therapy, pain management, and treatment of respiratory diseases.</p>

<p>ß-Endorphin, also known as Equine ß-Endorphin, is a polypeptide hormone that is a member of the endorphin family. It is a peptide consisting of nine amino acids. ß-Endorphin has been found in the pituitary gland and in other tissues in concentrations much higher than those of other endorphins. Beta-endorphin is thought to be involved in pain relief and stress relief.</p>

<p>Big Endothelin-3 (Human, 1-41 Amide) is a precursor molecule of the Endothelin-3 (ET-3) peptide, that belongs to the large family of endothelin peptides which activate the G-protein coupled receptors ETA and ETB. However ET-3 has lower affinity for the ETA receptors compared to Endothelin-1 (ET-1) and Endothelin-2 (ET-2), whereas all three endothelins have similar affinity for ETB receptors. As ETB receptors make up around 90% of the endothelin receptors found in the cerebral cortex in humans, ET-3 can be nicknamed the ‘brain endothelin’. Also through ET-3’s activation of ETB receptors, ET-3 is involved in the development of the enteric nervous system which controls within the gut, blood flow, secretion and intestinal motility. This product has disulfide bonds between Cys1-Cys15 and Cys3-Cys11.</p>

Ghrelin is a peptide hormone that regulates appetite, energy balance, meal initiation and nutrient sensing. Ghrelin is produced in the stomach, but is also found in the blood, brain, and other tissues.. It influences bodily functions through associating with growth hormone secretagogue receptors (GHS-R) through its unique N-octanoyl group which is linked to its serine 3 residue covalently. It wider functions are in the regulation of insulin resistance, diabetes and obesity. On top of this Ghrelin is also found to be involved with glucose homeostasis, energy homeostasis, cardio-protective effects, bone metabolism and is a potential target for cancer. Therefore it can be used to develop therapies for a whole spectrum of diseases. This molecule is used as a research tool for studying cell biology and pharmacology. This product is available in the salt form: Trifluoroacetate.

<p>Endothelin-1 is a peptide that acts as a vasoconstrictor and plays an important role in the regulation of blood pressure. Endothelin-1 is also an endogenous ligand for two G protein-coupled receptors, ETA and ETB. Interesting Endothelin-1 is the most abundant isoform and is expressed in endothelial cells of every blood vessel. It exerts its vasoconstrictor effects through binding to ETA receptors located on the smooth muscle. This product has disulfide bonds between Cys1-Cys15 and Cys3-Cys11 and is available as a 0.1mg vial.</p>

<p>This is a synthetic peptide that can be used as an enzyme substrate for the study of caspase activity. It is a peptide that has been designed to mimic the sequence of amino acids in the active site of caspase-7 and caspase-3. This peptide is useful for biochemical research, especially in the study of apoptosis.</p>

<p>Fmoc-γ-Abu-OH is a fatty acid that belongs to the group of neurotrophic factors. It has been shown to have neuroprotective properties in vitro and in vivo, and its mechanism may be related to its inhibition of apoptotic cell death. Fmoc-γ-Abu-OH also has pharmacokinetic properties, which are dependent on the route of administration. This compound is absorbed through the gastrointestinal tract and distributed throughout the body with a half-life of approximately 12 hours. Fmoc-γ-Abu-OH binds to β-catenin and inhibits its degradation by proteasomes, thereby increasing its levels in cells.</p>

<p>Boc-γ-Abu-OH is a model drug used in peptide synthesis. It is a building block that can be used to form the amino acid γ-Abu. This amino acid has an unusual β-amino group, which is coupled with the Boc group using photorelease chemistry. The resulting compound can be used as a building block for dendrimer or convergent syntheses.<br>Boc-γ-Abu-OH reacts with dimethoxybenzene and dendron to form γ-Abu. The resulting product can be reacted with other molecules, such as diamines and benzyl halides, to produce analogues of γ-Abu. This process allows for the synthesis of new compounds that have not been previously reported in the literature.</p>

<p>A hydroxamate-based inhibitor of collagenase, gelatinase, and TACE. TACE stands for Tumor Necrosis Factor-α Converting Enzyme. It is also known as ADAM17 (A Disintegrin and Metalloproteinase 17)</p>

<p>Peptide H-DYWSTVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Boc-D-Asp(OcHex)-OH is a peptide that belongs to the group of activators. It binds to the receptor and induces a conformational change in the receptor protein, which leads to activation of an ion channel. Boc-D-Asp(OcHex)-OH is also known as orexin A, which is a peptide that regulates appetite and sleep. This compound has been shown to stimulate the release of histamine from mast cells and inhibit tumor necrosis factor production. It has been used as a research tool for studying protein interactions and ligand binding. Boc-D-Asp(OcHex)-OH has been shown to be an inhibitor of calcium channels, potassium channels, and sodium channels in vitro at low concentrations (10 μM).</p>

<p>6-Azido-Hexanoic Acid is a lysine derivative that is used for Click Chemistry, which involves the use of reactive nitrenes, such as azides, to create stable covalent bonds with other molecules. This product is also used in diagnostic agents and has shown anticancer activity against prostate cancer cells. 6-Azido-Hexanoic Acid can be synthesized using Click Chemistry and x-ray crystal structures have been determined. The structure consists of a cyclic peptide that contains an amide bond between two lysine residues. The compound has a neutral pH and can be detected by gravimetric analysis.</p>

Peptide H-His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Peptide Ac-TYRPPQPAWMFGDPHIC-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>PAMP-12 is a peptide that can activate the human immune system. It can be used as a research tool for studying protein interactions and receptor ligand pharmacology. PAMP-12 is an inhibitor of ion channels, which are proteins that regulate the flow of ions through cell membranes. The CAS number for this peptide is 196305-05-2.</p>

<p>Fmoc-Ile-OH is a sodium salt that is used in the synthesis of peptides. It provides the hydroxyl group to the peptide chain, and can be used in solid-phase synthesis. The protonated form of Fmoc-Ile-OH is useful for acetonitrile solvents. Fmoc-Ile-OH has shown antibacterial activity against gram-positive bacteria such as Staphylococcus aureus and Streptococcus pneumoniae. Clinical development of this drug has been successful in treating infections caused by multidrug resistant bacteria, such as MRSA, Acinetobacter baumannii, and Pseudomonas aeruginosa.</p>

<p>Siastatin B is a peptide that can be used as a research tool for studying protein interactions. It has been shown to be an activator of ligand-gated ion channels, such as nicotinic acetylcholine receptors and glutamate receptors. Siastatin B also binds to the neurotoxin receptor, which leads to the inhibition of the binding of neurotoxins to this receptor. The inhibitory activity of siastatin B is reversible and competitive with respect to the neurotoxin receptor. Siastatin B also inhibits cell proliferation at high concentrations.</p>

<p>This Neuroendocrine Regulatory Peptide-1 (rat) product can be used as an endogenous suppressor of vasopressin release and is available as a 0.1mg vial. The neuroendocrine regulatory peptide-1 (NERP1) is derived from VGF and it colocalizes with vasopressin in the hypothalamus and it has been found that NERPs prevent vasopressin release from the hypothalamus. Thus NERP1 is involved in body fluid homeostasis through modulating the release of vasopressin.</p>

<p>Boc-Pro-OH is a synthetic amino acid that is used in the preparation of samples for gas chromatography. Boc-Pro-OH has antiinflammatory activity, and can be used to treat cancer. It is also used as an intermediate in the synthesis of amides, which are important in pharmaceuticals. Boc-Pro-OH is soluble in water and carbonate buffer solutions, but insoluble in ethanol. The chemical structure of this molecule is unusual because it contains a Boc group.</p>

CLEAR-OXTM is a highly effective polymer-supported reagent for the formation of disulfide bonds. Developed by Peptides International, incorporated to the Cymit Quimica Group through vivitide, CLEAR-OXTM combines the power of solid phase chemistry with the versatility of solution-phase reactions. CLEAR resin, compatible with both aqueous and organic environments, is transformed to CLEAR-OX through attaching a lysine-preformed cyclic Ellman’s reagent (DTNB) to a CLEAR polymeric support. Since the mechanism is based on peptide capture, sensitive residues such as Tyr, Trp, and Met are not affected, leading to increased purity and yield. Single disulfide-bridged peptides with constrained amino acids have been successfully produced using CLEAR-OX with various ring sizes and lengths. Oxidations are performed at higher concentrations than solution methods, leading to reduced solvent use at scale. Furthermore, oxidations can be carried out immediately after cleavage with only two-fold CLEAR-OX excess to obtain satisfactory yields. There is also potential for recycling and automation.

<p>Peptide H-GSPAINVAVHVFR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

H-His-D-Trp-D-Lys-Trp-D-Phe-Lys-NH2 is an inhibitor of cyclase that blocks the conversion of ATP to cAMP. It has shown to have potential as a biomarker for cancer tissues and can be used in experimental models of cancer. HHDLKPDTDLKYSHN2 also inhibits phosphodiesterase, which is involved in the breakdown of cAMP, and can be used to treat bowel disease.

<p>OVA Peptide (323-339) is a Chicken ovalbumin fragment that has been shown to have an immune checkpoint activity. It has been shown to be reactive with ISQAVHAAHAEINEAGR and can be used in the treatment of infectious diseases. This peptide is also used for histological analysis of microglia and toll-like receptor expression in skin cancer. OVA Peptide (323-339) also has the potential for use as a basic protein in α7 nicotinic acetylcholine therapy.</p>

<p>E-64 is a chemical inhibitor that binds to the ATP synthase in mitochondria, inhibiting oxidative phosphorylation. This inhibition of mitochondrial energy production leads to cell death by apoptosis. E-64 has been shown to inhibit tumor growth in vitro and in vivo by inducing autophagy and inhibiting cancer cell proliferation. E-64 has also been shown to have proteolytic activity against serum proteins, which may be due to its ability to bind to the phosphate groups of proteins.</p>

<p>Abz-Gly-Phe(NO2)-Pro-OH is a peptide that has been shown to have antihypertensive activity. It also has radical scavenging properties, and it can be used as an amino acid composition marker. Abz-Gly-Phe(NO2)-Pro-OH has been shown to inhibit the growth of faecalis and subtilis, which are both Gram positive bacteria. The peptide has also been shown to have inhibitory properties against proteolytic enzymes from bovine casein, human serum and rat blood pressure.</p>