Peptides

<p>Peptide H-SGSDEVQVGQQR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-RLTDQSRWSW-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-LLIYDASNLETGVPSR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-AANMHAQIK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-DLEMLAPYIPMDDDFQL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>K. phaffii binding peptide is used in protein purification. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-WEHR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>PSD95 peptide is a PSD95 fragment. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Peptide H-DPIYALSWSGMAGGC-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Peptide H-IQNTGDYYDLYGGEK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Peptide H-REPLACE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Overlaping peptide library of ovalbumin, 15 amino acids per peptide with offset 11. Purity crude. All peptides are pooled in a single tube.</p>

<p>H-Thr(tBu)-2-ClTrt-Resin (100-200 mesh) 1% DVB is a resin for peptide synthesis. It is used to immobilize amino acids, thiols, and other building blocks in order to synthesize peptides. This resin can be used for a variety of applications, including the synthesis of small organic molecules, oligonucleotides, and polysaccharides. H-Thr(tBu)-2-ClTrt-Resin (100-200 mesh) 1% DVB has been shown to react with amines and thiols.</p>

<p>Peptide H-HGESAWNLENR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

CLEAR-Base Resin (HCl) is a high-purity resin that has been used in the study of protein interactions, such as receptor and ligand binding. CLEAR-Base Resin (HCl) is also an inhibitor that can be used to block ion channels.

Peptide H-ANIKLSVQMKLFKRHLKWKIIVKLNDGRELSLD-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Peptide H-MGETLGDSPIDPESDSC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

H-Cys-Gly-OH is a cyclic peptide that has potent antitumor activity. It was synthesized from glutathione and cysteine, which are naturally occurring amino acids in the human body. The mechanism of action of H-Cys-Gly-OH is not well understood, but it may be due to its ability to bind to α1-acid glycoprotein and other proteins in the blood. The compound also has a redox potential, fluorescence spectra, and structural analysis that can be used for identification purposes. This molecule is stable at acid pH and is easily soluble in water or organic solvents. H-Cys-Gly-OH can be analyzed by titration calorimetry or cyclic voltammetry methods.

Myelin PLP (57-70) is a peptide that is immunogenic and biochemically active. It has been shown to have immunogenic properties and can be used as an adjuvant for vaccines. Myelin PLP (57-70) is a peptide fragment of myelin basic protein that has been shown to be immunogenic in animal models. It induces an antibody response against myelin basic protein, which can be used for the treatment of multiple sclerosis. 6-Fluoro-3-indoxyl-beta-D-galactopyranoside Tilmicosin 3-Desacetylcefotaxime potassium Gatifloxacin Myelin PLP (57-70)

Peptide Fmoc-AACK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Amino acids 1-10 of the peptide hormone Ghrelin which is found in the stomach, brain and other tissues and plays a key role in regulating energy balance. Ghrelin associates with growth hormone secretagogue receptors (GHS-R) through its unique N-octanoyl group which is linked to its serine 3 residue covalently. As a result it is able to influence the body in various ways such as stimulating appetite, nutrient sensing, meal initiation and the regulation of insulin resistance, diabetes and obesity. Its wider functions are also associated with glucose homeostasis, energy homeostasis, cardio-protective effects, bone metabolism and its potential to be a target for cancer means that it can be used to develop therapies for a whole spectrum of diseases. This molecule is used as a research tool for studying cell biology and pharmacology.</p>

<p>Peptide H-FQSGQVLAALPRTSR-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

In this special TentaGel resin, the PEG spacer is attached to the polystyrene/DVB matrix by a cleavable linkage. Therefore, the PEGylated compound can easily be cleaved and separated from the insoluble support. This can be achieved with either 10 mL/g of TFA/thioanisole (95:5) for 12 hours at room temperature, or with 10 mL/g of TFA/trimethylsilyl bromide/thioanisole (94:1:5) for 1 hour at room temperature. TentaGel is a gelatinous resin, an important support for solid phase synthesis. TentaGel resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol). The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. Even less soluble peptides may be completely solubilized with this linker. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix. (90 µm) 0.2-0.25 meq/g Product Application: Using this resin, cleavage yields the POE-peptide conjugates.

<p>Peptide H-IL^DTAGR^EEY-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Fmoc-Gln(Trt)-Rink-Amide MBHA Resin is a peptide resin that can be used as an activation and coupling agent for the synthesis of peptides. It is also used in the production of antibodies, and has been shown to inhibit ion channels. Fmoc-Gln(Trt)-Rink-Amide MBHA Resin is a high purity material with a CAS number, which can be used in research tools, cell biology, and pharmacology.

<p>Antimicrobial peptide consisting of disulfide bonds between Cys2-Cys30, Cys4-Cys19, and Cys9-Cys29. Alpha-defensin-4 is a small, cationic peptide that is part of the alpha-defensin family of antimicrobial peptides in humans. It is primarily produced by neutrophils, which are a type of white blood cell that plays a critical role in the immune response to bacterial infections.<br>Alpha-defensin-4 is known to have broad-spectrum antimicrobial activity against a wide range of bacterial pathogens, including both Gram-positive and Gram-negative bacteria. Like other alpha-defensins, alpha-defensin-4 achieves its antimicrobial activity by disrupting the cell membranes of the pathogens, leading to cell lysis and death.<br>In addition to its antimicrobial activity, alpha-defensin-4 has been found to have other functions in the body, including modulating the immune response and promoting tissue repair. It has also been implicated in the pathogenesis of certain inflammatory and autoimmune diseases, including rheumatoid arthritis and psoriasis.<br>Alpha-defensin-4 is typically found in various bodily fluids, including blood, urine, and semen, and its levels can be used as a diagnostic marker for certain conditions. For example, elevated levels of alpha-defensin-4 in joint fluid can be indicative of a bacterial infection in the joint, which can help to guide treatment decisions.</p>

Peptide H-SRPYSFGL-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Dnp-Pro-beta-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2 is a versatile building block that can be used in the synthesis of complex compounds, research chemicals and reagents. It has been shown to be useful in the synthesis of high quality, useful intermediates and reaction components. Dnp-Pro-beta-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N--Me--Abz)-NH2 is also a useful scaffold for the preparation of biologically active compounds.</p>

Peptide H-VASSGLQSVVHR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

HiGom is a venom that belongs to the group of proteins that can produce reactive oxygen species. It has been shown to inhibit mitochondrial membrane potential, cellular viability, and the production of reactive oxygen species. HiGom has also been shown to inhibit the production of inflammatory cytokines and chemokines in response to chronic pain. This protein may be useful for cancer treatment as it has been shown to inhibit tumor growth by inducing apoptosis and inhibiting angiogenesis.

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Peptide H-GLTVLPPLL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Gly-Gly-Gly-Gly-Arg-Gly-Asp-Ser-Pro is a peptide used as an activator in research. It can be used to study protein interactions and the effects of ligands on ion channels and receptors. Gly residues are able to form hydrogen bonds, which is why they are often used as spacers in proteins. This peptide has a high purity and CAS number.</p>

<p>H-Gln(Trt)-2-ClTrt-Resin (100-200 mesh) 1% DVB is a resin for the synthesis of peptides. It is a building block that can be used to synthesize peptides. H-Gln(Trt)-2-ClTrt-Resin (100-200 mesh) 1% DVB is an alcohols, amines, and thiols resin that can be used to synthesize peptides. H-Gln(Trt)-2-ClTrt-Resin (100-200 mesh) 1% DVB has been shown to react with thiols, alcohols and amines, which are building blocks for peptide synthesis.</p>

<p>Peptide H-LIQNSLTIER^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide LCBiot-AHGVTSAPDTRPAPGSTAPPA-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-DVSQSSISFQIEK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Peptide H-ETPAATEAPSSTPK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Peptide H-PEPAKSAPAPKKGSKKAVTKA-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Suc-Ala-Ala-Pro-Val-pNA is a synthetic peptide that is used as a research tool to study neutrophil function. It has been shown to have a dose response curve and can be hydrolyzed by esterases. Suc-Ala-Ala-Pro-Val-pNA can also inhibit the activity of proteolytic enzymes, such as kallikrein and pancreatic elastase, and has an absorption maximum at 270 nm. The sequence of this peptide was derived from sequences found in the protein maldiophorin A, which are found in molluscs.</p>

<p>Peptide H-VFTPLEVDVAK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-YSTDVSVDEVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Peptide H-IVASTLSNPELFEEWTGNVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>When 99mTc-labeled, this cyclic RGD dimer is a useful tool for tumor imaging. This novel galacto RGD dimer has enhanced hydrophilic properties that improve biodistribution and tumor-imaging in comparison to 3P-RGD2 tracer. This product is available as a trifluoroacetate salt.</p>

<p>Peptide H-VLTEIIASR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Marfey's reagent is a mixture of l-tartaric acid, hydrochloric acid and trifluoroacetic acid. It is used to determine the presence of β-amino acids in urine samples by reacting with the amide group on the β-amino acid. The reaction produces a white precipitate that can be filtered and analyzed using a UV spectrophotometer or LC/MS/MS. Marfey's reagent has significant cytotoxicity and should not be used in cell culture experiments.

TET 830 modified/T-helper epitope from tetanus toxoid – AQYIKANSKFIGITEL

<p>Peptide H-LSGLLDLALGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Peptide H-SDVVYTDWK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Peptide H-DLQVNSL^QTV-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Peptide H-EAEDL^QVGQVELGGGPGAGSLQPLALEGSLQ-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Peptide H-VSVFVPPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-IYNGDYYR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-VLEDSDLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-KLVVVGADGV^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Peptide Biot-PPAHGVTSAPDTRPA-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Peptide H-YSSLAEAASK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-Gly-2-ClTrt-Resin (100-200 mesh) 1% DVB is a building block that is used as an amine or thiol in peptide synthesis. It is also used as a tool for the synthesis of alcohols and resins.</p>

Consisting of the disulfide Bonds: Cys6- Cys22, Cys9-Cys12, Cys10- Cys18, and Cys13-Cys21 and of the trifluoroacetate salt form, this product can be used as an internal standard for Hepcidin assays.Hepcidin-24 is a peptide hormone that plays a key role in the regulation of iron metabolism in the body. It is produced by the liver and is secreted into the bloodstream, where it interacts with cells in the intestine and other tissues to control the absorption and distribution of iron. Hepcidin acts as a negative regulator of iron uptake and release by binding to and inhibiting the activity of ferroportin, a protein that facilitates the export of iron from cells into the bloodstream. When hepcidin levels are high, ferroportin activity is reduced, leading to decreased iron absorption from the diet and reduced iron release from cells. When hepcidin-24 levels are low, ferroportin activity is increased, leading to increased iron absorption and release. Imbalances in hepcidin levels can lead to a variety of disorders, including iron-deficiency anemia, hemochromatosis (an iron overload disorder), and anemia of chronic disease. Therefore, hepcidin-24 is a key target for the development of treatments for these and other iron-related disorders. In addition to its role in iron metabolism, hepcidin has been shown to have antimicrobial properties, as it can inhibit the growth of certain bacteria and fungi. It may also be involved in the regulation of immune function and inflammation.

<p>Peptide H-VTVAGLAGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-His(Trt)-2-ClTrt-Resin (200-400 mesh) 1% DVB is a resin for peptide synthesis. It contains thiols, building blocks, alcohols, amines, and other functional groups. The resin is used as a building block in the synthesis of peptides.</p>

H-Met-Gly-Pro-AMC·HCl is a complex organic compound. It is often used as a reagent in organic synthesis, as well as being a useful intermediate for the production of other fine chemicals. H-Met-Gly-Pro-AMC·HCl is useful for producing speciality chemicals and research chemicals, and can be used as a versatile building block.

Peptide H-LSAPGSQR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Fmoc-Phe-Wang Resin is a research tool that is used as an activator, ligand, or receptor for cell biology and protein interactions. It is also used for the synthesis of peptides. Fmoc-Phe-Wang Resin has been used in pharmacology to study ion channels and high purity proteins with high affinity. This resin can be used in antibody production and other life science applications.

Fmoc-Trp-Wang Resin (100-200 mesh) 1% DVB is a peptide resin that is used in the solid phase synthesis of peptides and small molecules. This product has been shown to be an effective inhibitor for Ion channels, Receptor, Ligand, and even Cell Biology. It is also a high purity reagent that can be used in a variety of applications including Pharmacology and Protein interactions. The Fmoc-Trp-Wang Resin (100-200 mesh) 1% DVB is available for purchase with CAS No. 680904-06-4.

<p>RGD Peptide with PEG Spacers for more efficient binding to lipid surfaces with the one letter code sequence: c(RGDfK(PEG-PEG)) where PEG = 8-Amino-3,6-Dioxaoctanoic Acid.<br>This product may requires further derivatization before use.</p>

RGD peptide with a Biotin Reporting Tag and PEG Spacers for more efficient binding to Lipid surfaces. This product may require further derivatization before use. The one letter sequence for this peptide is: c(RGDfK(Biotin-PEG-PEG)) where PEG = 8-Amino-3,6-Dioxaoctanoic Acid.

MOG (92-106) is a peptide that is derived from myelin basic protein. It has been shown to be immunogenic and can induce the production of antibodies in animals. MOG (92-106) also induces demyelination in mice.

Fmoc-Asp(OtBu)-Wang resin is a 1% DVB resin that can be used as an inhibitor of peptide synthesis. It has been shown to selectively inhibit the binding of the L-type calcium channel, which is a cell membrane protein that affects the transport of calcium ions in and out of cells. Fmoc-Asp(OtBu)-Wang resin binds to the receptor site, preventing the natural ligand from binding. This inhibition prevents the activation of ion channels and reduces calcium ion influx into cells, leading to an anti-inflammatory effect.

<p>Peptide H-VNSV^IEK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>DOTA-Glu-[Cyclo(Arg-Gly-Asp-D-Phe-Lys)]2 is a trifunctional cyclic peptide that can be derivatized with various groups such as radiolabels. It has been shown to have strong affinity for the integrin receptor and can be used for targeting of tumors. DOTA-Glu-[Cyclo(Arg-Gly-Asp-D-Phe-Lys)]2 has also been found to inhibit cell proliferation and induce apoptosis in tumor cells.</p>

Lysostaphin is a bacteriolytic enzyme that is produced by the bacteria Staphylococcus simulans. It cleaves the cross-linked pentaglycine bridges in bacterial cell walls which are essential for their structural integrity. Lysostaphin displays a broad spectrum of activity against Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). The recombinant form of lysostaphin has been expressed in E. coli and can be used to produce large quantities of lysostaphin for therapeutic use. Expression of lysostaphin in E. coli has also allowed for the production of other polypeptides with antimicrobial properties, such as the clostridial bacteriocins and staphylokinase.

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Peptide Ac-SVL-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Viloxazine is a selective inhibitor for norepinephrine uptake over serotonin (5-HT) uptake in rat hypothalamic synaptosomes. It has been studied for its potential uses in treating attention-deficit hyperactivity disorder (ADHD) and depression.Viloxazine hydrochloride is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&amp;D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>

<p>Peptide H-HSQPWQVLVASR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Cyclo(Arg-Gly-Asp-D-Tyr-Cys) is a peptide that is used as a research tool to study the activation of ion channels. It activates the channel by binding to the receptor and inducing conformational changes in it. Cyclo(Arg-Gly-Asp-D-Tyr-Cys) is also used as an inhibitor of protein interactions, such as antibody and ligand interactions. CAS No.: 438286 28</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>This product is an RGD Peptide containing a Thioacetyl Group for Linking to Liposomes. It may require further derivatization and deprotection before use</p>

<p>IFN-g Mouse is a recombinant protein that belongs to the group of cytokines. It has been shown to be an activator of cells and is used as a research tool. IFN-g Mouse is also an inhibitor of ion channels and ligands for cell surface receptors, which are important in regulating cellular processes. IFN-g Mouse contains a number of peptides and antibodies that can be used for research purposes.</p>

<p>Liver-Expressed Antimicrobial Peptide 2 (LEAP2) is a peptide that belongs to the family of antimicrobial peptides. LEAP2 is a potent activator of ion channels, which are membrane proteins that regulate the passage of ions through the cell membrane. LEAP2 can also inhibit protein interactions by binding to receptors and ligands on the surface of cells. LEAP2 has been shown to be a receptor for Ligand-gated ion channels, which are involved in many cellular processes such as neurotransmitter release, muscle contraction, and hormone release.<br>LEAP2 can be used as an inhibitor of the hyperpolarization activated cyclic nucleotide-gated (HCN) channels in neurons. These channels are important for regulating neuronal excitability and inhibiting neuronal activity following action potentials.</p>

<p>H-Leu-2-ClTrt-Resin (100-200 mesh) 1% DVB is a resin that has been used to synthesize peptides. It can be used as a building block for many other chemical reactions, such as cross-linking and oxidation. This resin is typically used in the synthesis of peptides with an amino acid sequence of H-Leu-2-ClTrt and contains 1% DVB. The resin can be used for the synthesis of small organic molecules, such as antibiotics, with a molecular weight between 500 and 2000 Da.</p>

H-Ala-Phe(para-Fluoro)-Arg-Cha-Cit-Tyr-NH2 is a peptide that has been shown to activate Protease Activated Receptor 1 (PAR1). PAR1 is the receptor for thrombin, which is the enzyme responsible for blood clotting. The peptide was found to be a potent activator of PAR1 in vitro and in vivo. It has also been shown to inhibit the production of angiotensin II, which can lead to hypertension. H-Ala-Phe(para-Fluoro)-Arg-Cha-Cit-Tyr-NH2 is a potential candidate for treating cardiovascular diseases such as hypertension.

<p>Urate oxidase is a flavoenzyme that catalyses the oxidation of uric acid to allantoin. It is present in many organisms, including fungi and primates. Urate oxidase catalyzes the oxidation of uric acid to allantoin via the reduction of oxygen to water with concomitant production of hydrogen peroxide. There are four forms of urate oxidase found in nature: tetrameric, dimeric, monomeric, and recombinant. The recombinant form has been shown to be effective against hyperuricaemia in primates and humans with lymphoid malignancies.</p>

<p>Fmoc-Phe-Rink-Amide MBHA Resin is a peptide resin that has been used as an inhibitor of protein interactions and as a research tool in the study of ion channels. It is a high purity resin that is free of any ligands, activators, or receptors. This product can be used to purify antibodies and other proteins. Fmoc-Phe-Rink-Amide MBHA Resin is also used as an activator of Protein A affinity chromatography and for the purification of antibodies and other proteins.</p>

Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 RA). It mimics the GLP-1 hormone, released in the gut in response to eating.  Semaglutide can enhance insulin secretion and suppress glucagon section in a glucose-dependent manner. It also increases gastric emptying time and reduces intestinal motility. This combination leads to a decrease in appetite. Semaglutide has a long half-life allowing weekly subcutaneous application. Semaglutide also has positive effects on heart, liver, and lung function. Semalgutide also slows the progression of the effects of Alzheimer’s disease. This is a heavy isotype-labelled version of semaglutide that is suited to peptide quantification by mass spectrometry. This allows it to be used as an internal standard for quantification of semaglutide. There are two phenylalanine residues isotopically labelled with carbon-13 (9) and nitrogen-15 (1); one valine is labelled with carbon-13 (5) and nitrogen-15 (1); two leucine residues labelled with carbon-13 (6) and nitrogen-15 (1). This semaglutide peptide has a mass increase of 40 compared to the unlabelled peptide.25nmol = 0.1mg

<p>Prolactin-releasing peptide (PrRP20) was originally identified for being able to stimulate lactin release. However, that is not considered its function anymore, it is reclassified as a neuropeptide with a role in energy balance, and an inhibitor of appetite. PrRP20 is considered a central neuromodulator found within the A1 and A2 noradrenergic neurons and neurons of the dorsomedial nucleus of the hypothalamus. PrRP20 binds with high affinity to the G protein coupled receptor GPR10. Binding can lead to activation of numerous signalling pathways including activation of mitogen-activated protein kinase/extracellular-regulated kinase (MAPK/ERK1/2) and cAMP response element-binding protein (CREB).  Not much is known about the binding mechanism and activation of GPR10. Use of PrRP20 and its analogs have aimed to provide greater insight to the binding and activation of GRP10 to better understand how this effects energy balance. With new links being made between diabetes and obesity with Alzheimer's disease it raises the question of whether PrRP20 and GP10 may be a factor in the disease development due to the colocalization in the same brain regions. Further study may lead to novel therapies for obesity, diabetes, and Alzheimer's disease in the future.</p>

<p>Penetratin is a cell-penetrating peptide (CPP), also known as a protein transduction domain (PTD), of which the first 16 amino acids are derived from the third helix of the Antennapedia protein homeodomain. Penetratin linked to a phosphodiester oligonucleotide is capable of permeating through neuronal cell membranes and down-regulating genes.</p>

<p>Ghrelin is involved in several physiological processes, including feeding and lipid accumulation, stress response, anxiety, cardiac performance, immunity and inflammation, taste sensation, reward-seeking behaviour, regulation of glucose metabolism and thermogenesis, memory, motivation and learning.Ghrelin is a peptide hormone that typically has a serine at the third residue and relies on modification with a fatty acid to give ghrelin its functional activity. In its modified form, ghrelin is an endogenous ligand for the pituitary gland's growth hormone receptor (GHS-R) and stimulates growth hormone release.Ghrelin acts on the hypothalamic arcuate nucleus as an orexigenic agent to stimulate appetite. Ghrelin is produced in the stomach as a precursor peptide preproghrelin, cleaved to ghrelin. Ghrelin circulates in the blood and can cross the blood-brain barrier. Levels of ghrelin respond to fasting conditions and allow signals about the energy status to be transmitted from the peripheral organs to the central nervous system to maintain energy homeostasis.Ghrelin is a valuable target for treating conditions such as anorexia, cachexia, sarcopenia, cardiopathy, neurodegenerative disorders, renal and pulmonary disease, gastrointestinal disorders, inflammatory disorders and metabolic syndrome.</p>

CPPs can transport molecules such as nucleic acids, proteins and imaging agents into cells of inter-est. PR9, Pas non-arginine, is an arginine rich CPP. It is composed of the nona-arginine: R9 and Pas which is a peptide penetrating accelerating sequence and it functions to export molecules out of endocytic vesicles. During a study in which PR9 was in complex with a Quantum dot probe (QD) it was evident that the PR9/QD complex was transported into the cell through endocytosis where it co-localises with actins, lysosomes, early endosomes and the nucleus. Due to the non-toxicity of the PR9/QD complex it can be used as a safe vector for biomedical purposes.It contains 5-Carboxyfluorescein (5-FAM), a widely used green fluorescent tag.

<p>Portion of EBV</p>

<p>A 26-residue fragment from BH3 only protein Bim, BH3 only proteins constitute a major proportion of pro-apoptotic members of the B-cell lymphoma 2 (Bcl-2) family of apoptotic regulatory proteins and participate in embryonic development, tissue homeostasis and immunity.</p>

<p>Protease activated receptors (PARs) are a distinctive four-member family of seven transmembrane G protein-coupled receptors (GPCRs) widely expressed in inflammatory cells. PARs are cleaved by certain serine proteases to expose a tethered ligand domain, this ligand domain then binds to and activates the receptors to initiate multiple signalling cascades. These PAR-activating proteases therefore represent PAR agonists. This PAR-2 agonist peptide mimics the sequence of the 'tethered ligand' and is therefore capable of activating the receptor independently of N-terminal proteolysis.PAR-3 is required for intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells and PAR-3 cooperates with PAR-1 to mediate the effect of thrombin on cytokine production and vascular cell adhesion molecule (VCAM-) 1 expression.PAR activation has been linked to inflammation, therefore compounds that mimic or interfere with the PAR-activating processes are attractive therapeutic candidates.</p>

The peptide Sapecin B exhibits antimicrobial properties against gram-positive bacteria. It is originally derived from the sarcophaga peregrine embryonic cell line, NIH-Sape-4.

<p>Peptide H-RKKRRQRRR-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Suc-LLVY-acid.</p>

<p>Autocamtide-2</p>

<p>a-Gliadin (229-246) is derived from Gliadin peptides, the component of wheat involved in the gastrointestinal symptoms of wheat allergy and Celiac Disease (CD). During wheat allergies histamines and leukotrienes are secreted due to gliadin peptide sequences cross-linking two IgE molecules on mast cells and basophils.The glutamine and proline rich peptides of which Gliadin is composed of are resistant to proteolysis during digestion, leaving them active in the gastrointestinal tract. Subsequently these are deamidated by tissue transglutaminase and can bind to HLA-DQ2 or DQ8. As a result in patients with the autoimmune disease CD, there is a Th1-mediated inflammatory immune response against these gliadin peptides.Gliadin can exert additional effects on the intestinal microbiota and ileal barrier function. It has been found that gut microbiota members such as Bifidobacterium and lactobacillus have the ability to digest and inactivate gliadin peptides hence reducing their inflammatory effects in the gastrointestinal system.</p>

Exendin-4 is part of a group of peptide hormones, the exendins. These are members of the glucagon superfamily of peptides and are secreted from the Gila monster lizard (Heloderma suspectum) venom gland. Exendins stimulate insulin secretion in response to rising blood glucose levels and modulate gastric emptying to slow the entry of ingested sugars into the bloodstream. Exendin-4 increases insulin sensitivity and improves glucose tolerance in humans and animals with diabetes. Exendin-4 is currently used for treating type 2 diabetes mellitus in its synthetic form, Exenatide.Exendin-4 shares 53% sequence homology, and specific activities, with glucagon-like-peptide-1 (GLP-1). Enteroendocrine L-cells produce GLP-1 upon nutrient ingestion, its central role relates to insulin secretion. Unlike GLP-1, exendin-4 is resistant to cleavage by plasma dipeptidyl peptidase IV (DPP-IV), resulting in a longer half-life and duration of action than GLP-1, as well as greater potency in vivo. Exendin-4 binds and activates the glucagon-like peptide-1 receptor (GLP-1R). In addition to its role in insulin sensitivity, exendin-4 also has a role in pancreas development and has anti-cancer properties.This exendin-4 contains AF647, a structural analog to Alexa Fluor® 647, a widely used far-red fluorescent dye. Its excitation is ideally suited to 594nm or 633nm. This dye is suited for low abundance targets as it has high initial brightness and a high photostability allowing detection of low abundance peptides. If you desire an alternative dye, please contact us to request a custom synthesis.