Peptides
Les peptides sont des chaînes courtes d'acides aminés liées par des liaisons peptidiques, jouant un rôle essentiel en tant que molécules biologiques dans divers processus cellulaires. Ils fonctionnent comme hormones, neurotransmetteurs et molécules de signalisation, et sont largement utilisés dans les applications thérapeutiques et diagnostiques. Les peptides sont également cruciaux dans la recherche pour étudier les interactions protéiques, les activités enzymatiques et les voies de signalisation cellulaire. Chez CymitQuimica, nous proposons une large sélection de peptides de haute qualité pour soutenir vos besoins en recherche et développement en biotechnologie et en pharmacie.
Sous-catégories appartenant à la catégorie "Peptides"
29799 produits trouvés pour "Peptides"
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Boc-Arg(Tos)-OH
CAS :Boc-Arg(Tos)-OH is a building block used in the synthesis of peptides. It is a solid-phase synthesis that can be used as a catalyst for transfer hydrogenation and transfer chemistry. Boc-Arg(Tos)-OH is typically used to produce lactam, amide, and dermorphin. This molecule is acetylated before use in the synthesis of peptides or proteins.
Formule :C18H28N4O5SDegré de pureté :Min. 95%Masse moléculaire :428.5 g/mol(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,4-diamino-4-oxobutanoyl]amino]penta noyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propan
CAS :Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Formule :C49H70N14O11Masse moléculaire :1,031.2 g/mol[Gly14]-Humanin
CAS :Humanin is an endogenous peptide which is encoded for by mitochondrial DNA. It has been described as a rescue factor due to it demonstrating the capabilities of abolishing neuronal cell death, therefore is can be used to as a potential treatment of Alzheimer’s disease. Another function of Humanin is it can inhibit mitochondira-dependent apoptosis through preventing the formation of apoptotic bodies and the release of Cytochrome C. Humanin has been found to be related to aging related cardiovascular disease (ACVDs) due to evidence of Humanin serum levels as age increases. Furthermore Humanin increases the expression of antioxidant defense system proteins and impedes complexes I and III from their activity in the electron transport chain in myocardial cells and mitochondria, therefore decreasing oxidative stress damage caused by H2O2. Humanin further reduces reactive oxygen species production and protects cardiomyocytes and fibroblasts, from oxidative stress. Overall Humanin has a variety of protective functions such as mitochondrial homeostasis and redox systems regulation, anti-aging, prevention of myocardial fibrosis, anti-inflammation, metabolism improvement and autophagy promotion. It has also been found to improve beta-cell survival and thus can be used as a diabetes treatment due to it improving insulin secretion and resistance. This Humanin product has had the serine at position 14 on the amino acid chain replaced with a Glycine. This modification has been known to enhance the cytoprotective activity of Humanin by 1000 fold and proves to be highly anti-apoptotic. Therefore this product is of scientific interest for research laboratories. It is available as a 0.5mg vial.Formule :C118H202N34O31S2Degré de pureté :Min. 95%Masse moléculaire :2,657.2 g/molH-ALLFIPR^-OH
Peptide H-ALLFIPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2
CAS :Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2 is a synthetic substrate for the enzyme sodium citrate synthase. Dnp is an inhibitor of the citrate synthase enzyme, which prevents the conversion of oxaloacetate to citrate and the formation of acetyl CoA. The use of deuterium has shown that this compound binds in a manner similar to but more stable than acetic acid. Polyclonal antibodies were raised against this synthetic substrate and found to be effective in inhibiting epidermal growth factor (EGF) synthesis by blocking the activation of EGF receptors on cell surfaces. This process reduces ulceration and cell proliferation in cell culture systems. The antibody also inhibits atherosclerotic lesion development in animal models, as well as collagen production by cells. This protein's tryptophan fluorescence indicates that it is a neutral peptide with a high degree of hydrophobFormule :C45H64N14O11Degré de pureté :Min. 95%Masse moléculaire :977.1 g/molH-DPGSAAPYLK^-OH
Peptide H-DPGSAAPYLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Liraglutide acetate
CAS :Liraglutide is a glucagon-like peptide-1 analog that has been shown to be an effective treatment for obesity. Liraglutide targets the adipose tissue and reduces the amount of glucose in the blood by increasing insulin sensitivity, lowering food intake, and reducing appetite. In addition, Liraglutide has been shown to suppress postprandial hyperglycemia and lower plasma glucose levels in patients with type 2 diabetes mellitus. Liraglutide also inhibits neuronal death induced by apoptotic stimuli, which may have potential use as a model system for neurodegenerative diseases such as Parkinson's disease. Liraglutide has also been shown to be an effective therapy for infectious diseases including Crohn's disease and ulcerative colitis. This drug has shown some effectiveness against atherosclerosis in animal models by inducing apoptosis in macrophages that are associated with lesions.Formule :C172H265N43O51Degré de pureté :Min. 95%Masse moléculaire :3,751.29 g/molGM CSF Human
GM CSF Human is a protein that belongs to the GM-CSF family. GM-CSF proteins are cytokines that activate neutrophils and macrophages, which play an important role in the immune system. This protein is a potent activator of receptor and peptides, as well as ion channels. It has been shown to inhibit ligand binding to receptors and inhibit the function of antibodies. The antibody can be used as a research tool for Cell Biology or to study the effects of drugs on ion channels. The CAS number for this protein is 57722-07-1.Degré de pureté :Min. 95%H-FRHDS-NH2
Peptide H-FRHDS-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Fmoc-FAVP
Peptide Fmoc-FAVP is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-YAFGYPS-NH2
Peptide H-YAFGYPS-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-WYQSIR^-OH
Peptide H-WYQSIR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.LCBiot-KPVSKMRMATPLLMQAL-OH
Peptide LCBiot-KPVSKMRMATPLLMQAL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Asp-Glu-Asp-Glu
CAS :Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFormule :C18H26N4O13Masse moléculaire :506.42 g/molAcetyl-ccbeta
The ccβ peptide has been used to study conformational changes in response to stimuli such as temperature and salt. The ccβ peptide adopts a three-stranded alpha-helical coiled-coil structure at low temperature and changes to an amyloid conformation with increasing temperature. The ccβ peptide can be used as a model for prion diseases and in amyloid studies.Masse moléculaire :2,093.2 g/molH-RLAVYQAGAR^-OH
Peptide H-RLAVYQAGAR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.P1A antigen
P1A was the first tumour antigen identified to be recognised by cytotoxic T cells. Tumour antigens are highly expressed on tumour cells however, they are also expressed during early embryogenesis then largely silenced in adulthood thus termed onco-fetal antigens. Targetting tumours expressing these antigens is possible due to their absence in adult tissue (apart from within the testes and placenta). The immune response to the P1A antigen is the major component of the tumour rejection response observed in normal mice. P1A antigen has been tested as a vaccine for tumours to induce P1A-specific CD8+ tumour-infiltrating lymphocytes (TILs). Therefore, the P1A antigen is a useful tool in the search in new cancer immunotherapies using targeted tumour-specific antigens.Masse moléculaire :1,105.6 g/molH-QGGFLGLSNIK^-OH
Peptide H-QGGFLGLSNIK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-LSITGTYDLK-OH
Peptide H-LSITGTYDLK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Formule :C50H83N11O17Couleur et forme :PowderMasse moléculaire :1,110.26 g/molSLC38A1 Blocking Peptide
A synthetic peptide for use as a blocking control in assays to test for specificity of SLC38A1 antibody, catalog no. 70R-1754Degré de pureté :Min. 95%H-VPEPCHPK^-OH
Peptide H-VPEPCHPK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Acetyl-TGF-β 2-LAPbeta (259- 269)
Latent TGF-β is a non-lysosomal glycoprotein with mannose 6-phosphate (Man-6-P) residues on its N-glycans. When it is released, latent TGF-β is bound to its latency-associated peptide (LAP), it must then be activated and released from LAP before it can bind to its cell surface-localised Man-6-P receptors and exert its biological activity. Activation can occur by various mechanisms in vivo, including those governed by integrins and thrombospondin. Mannose phosphorylation has also been implicated in this activation process. Man-6-P has been proposed as an anti-scarring therapy due to its ability to directly block the activation of latent TGF-β.Couleur et forme :PowderMasse moléculaire :1,267.6 g/molSAMs Peptide
CAS :Peptide SAMs Peptide is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Formule :C74H131N29O18S2Masse moléculaire :1,779.18 g/molAc-RFAAKAA-OH
Peptide Ac-RFAAKAA-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-AHIFDLAINK^-OH
Peptide H-AHIFDLAINK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Ac-CAY-NH2
Peptide Ac-CAY-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-Ser-Phe-Leu-Leu-Arg-Asn-OH
CAS :H-Ser-Phe-Leu-Leu-Arg-Asn-OH is a biocompatible polymer that has been shown to have strong antioxidative properties. This polymer has been used in the development of a new class of drug for the treatment of inflammatory bowel disease, which may be due to its ability to inhibit toll-like receptor activity. H-Ser-Phe-Leu-Leu-Arg-Asn-OH also has potent immunosuppressive and antiinflammatory activities, and is stable at doses up to 200mg/kg. These properties make this polymer an attractive candidate for use as a therapeutic agent in treating bowel disease.Formule :C34H56N10O9Degré de pureté :Min. 95%Masse moléculaire :748.87 g/molPTPRN Blocking Peptide
A synthetic peptide for use as a blocking control in assays to test for specificity of PTPRN antibody, catalog no. 70R-6312Degré de pureté :Min. 95%Nictide
LRRK2 is a leucine rich repeat kinase 2. Increase in LRRK2 kinase activity due to mutation has been linked to numerous forms of Parkinson disease (PD). Theoretically, identification of suitable inhibitors of LRRK2 could be the basis for treatments of PD. Markers of LRRK2 activity and function are available that may be clinically relevant in the future as prognostic indicators. Nictide is a substrate model peptide for LRRK2 activity in in vitro kinase assay analysis. -LRRK2 phosphorylates Rab GTPases and alters their association with effector proteins leading to changes in a vast array of cellular functions including the immune response. The use of in vitro kinase assays with small molecules substrates makes screening for LRRK2 inhibitors possible. Alongside nictide, LRRKtide is also used in the same in vitro assays as a substrate model peptide for LRRK2.- Nictide and LRRKtide are available in our catalogue.Masse moléculaire :2,748.5 g/molBTN2A1 Blocking Peptide
A synthetic peptide for use as a blocking control in assays to test for specificity of BTN2A1 antibody, catalog no. 70R-7238Degré de pureté :Min. 95%Myelin PLP (180-199)
Myelin PLP (180-199) is a peptide that has been shown to be immunogenic and biochemically active. It belongs to the group of peptides and biochemicals, which are organic compounds of high molecular weight. Myelin PLP (180-199) is an immunogenic compound that can be used as a vaccine adjuvant. It also has been shown to have anti-inflammatory activities, which may be due to its ability to inhibit prostaglandin synthesis.Formule :C92H144N23O30SDegré de pureté :Min. 95%Masse moléculaire :2,084.37 g/molAbz-Ala-Phe-Arg-Phe-Ser-Gln-EDDnp
CAS :Abz-Ala-Phe-Arg-Phe-Ser-Gln-EDDnp is a peptide that belongs to the group of picolinic acid. It has been shown to cause neuronal death and synergistic cell lysis in vitro. Abz-Ala-Phe-Arg-Phe-Ser-Gln-EDDnp inhibits the mitochondrial membrane potential, which leads to cytochrome c release, caspase activation, and subsequent apoptosis. Abz also inhibits basic protein synthesis and causes proteolytic degradation of cellular proteins.Formule :C50H63N15O13Degré de pureté :Min. 95%Masse moléculaire :1,082.15 g/molAc-FAOOFAOOFOOFAOOFAOFAFAF-NH2
Peptide Ac-FAOOFAOOFOOFAOOFAOFAFAF-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-EIDTVLPNK^-OH
Peptide H-EIDTVLPNK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-ATGIPDR^-OH
Peptide H-ATGIPDR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-VSAQQVQGVHAR^-OH
Peptide H-VSAQQVQGVHAR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-Gln-2-ClTrt-Resin (100-200 mesh) 1% DVB
H-Gln-2-ClTrt-Resin (100-200 mesh) 1% DVB is a resin that is used in peptide synthesis. It is an amine-thiol resin with a DVB backbone and HCl groups on the secondary amines. This resin can be used as a building block for peptide synthesis, and it has been used to synthesize peptides containing an N-terminal thiol group.Degré de pureté :Min. 95%H-AALEDTLAETEAR^-OH
Peptide H-AALEDTLAETEAR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Premelanosome Protein (PMEL) (C-Term)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolH-RF^-OH
Peptide H-RF^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-GSTLGLDIETATR^-OH
H-GSTLGLDIETATR-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool5Fam-LPYEGSLLLKLLRAPVEEV-OH
Peptide 5Fam-LPYEGSLLLKLLRAPVEEV-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Acetyl-Alpha-synuclein (1-13)
Acetylated α-synuclein (1-13) is derived from the alpha-synuclein intrinsically disordered protein which is found in the neurons and presynaptic terminals. Encoded by the SNCA1/PARK1 gene alpha-synclein is structurally composed of 140 amino acids, making up the three domains: N-terminal membrane binding domain, a hydrophobic non-amyloid-β component domain and a hydrophilic C-terminal domain. Usually alpha-synuclein plays a role in protecting neurons from apoptotic stimuli and is involved in synaptic vesical trafficking.However it has been found that the accumulation of alpha-synuclein aggregates can lead to neurodegenerative diseases such as Parkinson disease, dementia with Lewy bodies and multiple system atrophy. It is further involved in the fibrilisation of amyloid-b and tau which play a major role in Alzheimer disease. Amyloid fibrils are formed from alpha synuclein monomers within the cytosol and when bound to membranes these monomers can undergo conformational changes to form protofibrils and then ring like oligomers. This can result in the formation of transmembrane pores which disrupts the membrane, calcium homeostasis and signalling.Alpha-synuclein can be subjected to the post-translational modifications of phosphorylation and N-terminal acetylation. When acetylation occurs at the N-terminus of an alpha-synuclein monomer, the intramolecular hydrogen bonds are altered thus reducing the rate of alpha-synuclein aggregation and the strength at which it interacts with the membrane is increased.
Masse moléculaire :1,524.8 g/molAc-SLRRYP-NH2
Peptide Ac-SLRRYP-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.R5
The peptide R5 is made up of 19 amino acids and it precipitates SiO2 nanostruture silica, using its RRIL motif. It is one of the repetitive peptide sequences forming the protein silaffin sillp in Cylindrotheca fusiformis, a marine diatom.Masse moléculaire :2,012.1 g/molDes-n-Octanoyl-[Ser3]-Ghrelin (Rat)
The peptide Des-n-octanoyl-[Ser3]-ghrelin (DOG) is a synthetic analogue of ghrelin, the only known natural ligand for the growth hormone secretagogue receptor. DOG binds to the ghrelin receptor and activates it, thereby stimulating growth hormone release from the anterior pituitary gland. In a rat model, DOG counteracts weight gain caused by high-fat diet. It also increases insulin sensitivity in diabetic rats and acts as an appetite suppressant in non-diabetic rats. As such, this peptide has potential as a therapeutic agent for obesity and diabetes.Formule :C139H231N45O41Degré de pureté :Min. 95%Masse moléculaire :3,188.67 g/molHistone-H2A-(107-122)-Ac-OH
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFormule :C81H140N20O23Masse moléculaire :1,762.1 g/molH-VPQTPLHTSR^-OH
Peptide H-VPQTPLHTSR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-FNLAGNHEQEFLR^-OH
Peptide H-FNLAGNHEQEFLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Bmf-Y peptide
The Bmf-Y peptide is a short fragment derived from the protein Bmf (Bcl-2-modifying factor), which is a pro-apoptotic member of the BH3-only family of proteins. These proteins play crucial roles in regulating apoptosis by interacting with other members of the Bcl-2 family, such as Bax and Bak, to promote cell death. The Bmf-Y peptide specifically refers to a portion of the Bmf protein that contains the BH3 domain—a critical region responsible for its interaction with anti-apoptotic Bcl-2 proteins. This interaction inhibits the survival-promoting activity of Bcl-2 proteins, thereby triggering apoptosis. In research and therapeutic contexts, peptides like Bmf-Y are used to mimic the action of natural BH3-only proteins, promoting apoptosis in cancer cells or other diseased tissues by targeting the apoptotic pathways regulated by Bcl-2 family proteins. By doing so, they help in restoring the natural cell death process in cells that are evading apoptosis, such as in cancer.H-FLASVSTVLTSK^-OH
Peptide H-FLASVSTVLTSK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-RGDNNL^TRIVGGQE-OH
Peptide H-RGDNNL^TRIVGGQE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-YLFSVHWPPLKA-NTBiot
Peptide H-YLFSVHWPPLKA-NTBiot is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Bid BH3 Peptide
The Bid BH3 Peptide is derived from the pro-apoptotic proteins Bid (BH3-interacting domain death agonist) and BH3, which are both members of the BCL-2 family proteins and activate the BAX and BAK proteins to promote apoptosis.The process of apoptosis can be activated by the intrinsic or extrinsic pathways, the former is activated by stress stimuli such as DNA damage and nutrient deficiency, while the latter is induced through activation of the death receptors FAS and TRAIL.The BCL-2 family's transmembrane anchor at the C-terminus allows them to locate at the mitochondrial outer membrane and play a vital role in apoptosis.Within the mitochondria BH3 molecules, containing the members BID, BIM, PUMA and NOXA, can be activated by the intrinsic pathway. These in turn can initiate the homo-oligomerisation of BAX and BAK which induce mitochondrial outer membrane permeabilisation (MOMP) and the release of cytochrome c into the cytosol. Here cytochrome c associates with APAF-1 and dATP, ultimately activating effector caspase3/7 and apoptosis.In addition to Bid's role in apoptosis, it also plays a role within a mitosis checkpoint and genomic stability maintenance. Bid's main role is in the extrinsic pathway of apoptosis. When the death receptors are activated Caspase-8 generates tBid through the cleavage of Bid. This then locates to and targets Bax to the outer mitochondrial membrane (OMM) where it induces permeabilisation and hence apoptosis.Couleur et forme :PowderMasse moléculaire :2,308.2 g/molH5N1 Labeled 5-peptide Mixture
Pack contains 100 vials. Peptide sequences:
H5N1 labeled seq1 H-IQIIPK^-OH H5N1 labeled seq2 H-LVLATGLR^-OHH5N1 labeled seq3 H-EFNNLER^-OH H5N1 labeled seq4 H-TLDFHDSNVK^-OHH5N1 labeled seq5 H-EEISGVK^-OH R^ = Arginine (U-13C6,15N4)K^ = Lysine (U-13C6,15N2)1nmol/peptide/vial and provided as dry aliquotsDegré de pureté :Min 98%H-VVSVLTVLHQDWLNGKEY^K-OH
Peptide H-VVSVLTVLHQDWLNGKEY^K-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Fmoc-Cys(tBu)-Wang Resin (100-200 mesh) 1% DVB
Fmoc-Cys(tBu)-Wang Resin (100-200 mesh) is a research tool for use in the synthesis of peptides and proteins. It is an activated resin that can be used to synthesize peptides with a C-terminal cysteine. The resin is suitable for the coupling of amines, alcohols, thiols, phosphates and other compounds. Fmoc-Cys(tBu)-Wang Resin (100-200 mesh) has been shown to be an effective inhibitor of ion channels and may have potential as a therapeutic drug for the treatment of epilepsy.
Degré de pureté :Min. 95%HXB2 gag NO-46
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolMasse moléculaire :1,624.8 g/molH-LPDATPK^-OH
Peptide H-LPDATPK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Fmoc-Gly-Pro-OH
CAS :This is a vivitide catalogue product. Please send your vivitide product enquiry to sales@vivitide.com for an up-to-date price and availability.Formule :C22H22N2O5Degré de pureté :Min. 95%Masse moléculaire :394.43 g/molHXB2 gag NO-26
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolMasse moléculaire :1,788 g/molMacropin 2
This anti-microbial peptide (AMP) has been shown to cause lysis of several human cancer cell lines. Macropin-2 is most potent against CCRF-CEM T lymphoblastoid (human acute lymphoblastic leukemia) cells. At higher concentrations Macropin-2 also causes lysis of human umbilical vein endothelial cells (HUVEC), rat intestinal epithelial cells (IEC), human cervix carcinoma (HeLa) cells and human colon adenocarcinoma (SW480). Macropin-1 is also available in our catalogue.
Masse moléculaire :2,007.53 g/molPADRE scrambled
SB-peptide offers the scrambled version of PADRE peptide. AAATLWKAAKFVA can be used as a negative control of PADRE peptide studies. SB-peptide offers also PADRE peptide (see section PADRE peptide). PADRE peptide: Pan HLA DR-binding epitope is a universal peptide that activates antigen specific-CD4+ T cells which can be used as an agonist adjuvant in immunotherapeutic vaccine development. Pan HLA DR-binding epitope has been proposed as a carrier epitope suitable for use in the development of synthetic and recombinant vaccines. It has been demonstrated that PADRE may be an universal approach to control tumor cells. Moreover, PADRE is also used in research about an immunosense approach to develop a base for development of vaccines against toxoplasmosis to protect person with HLA-A*03 type. Pan HLA DR-binding epitope can be also used as tool to study the autoreactive T cell response.Formule :C65H100N16O14Couleur et forme :PowderMasse moléculaire :1,347.60 g/molH-CGKGLSATVTGGQK^GRGSR-OH
Peptide H-CGKGLSATVTGGQK^GRGSR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-VAVVR^-OH
Peptide H-VAVVR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Pap12-6
Broad-spectrum antibacterial, active against multidrug-resistant Gram-negative bacteria. Acts though permeabilizing the bacterial membrane and also shows anti-inflammatory activity via a TLR4-mediated NF-KB signaling pathway. Significantly improves survival in a mouse sepsis model.
Masse moléculaire :1,644.1 g/molH-GLPSSI^EK^-OH
Peptide H-GLPSSI^EK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Human Lysozyme (107-115)
Human Lysozyme (107-115) is derived from human lysozyme, a glycosidase enzyme which can kill both gram-positive and gram-negative bacteria. This can be carried out in a catalytic manner through the hydrolysis of peptidoglycan in the cell wall or alternatively in a non-catalytic manner. Due to the surface of bacteria being negatively charged, they are vulnerable to be targeted by the human lysozyme which is cationic. These antimicrobial properties can be used therapeutically as an anti-pseudomonal agent.Structurally the human lysozyme is comprised of four intramolecular disulphide bonds, four alpha helices within an alpha domain and β-sheets within a β-domain. Human lysozyme (107-115) is found within the α-domain.Masse moléculaire :1,212.7 g/molTemporin SHF
Temporin-SHf is a broad spectrum anti-microbial peptide (AMP) with activity against Gram-positive and Gram-negative bacteria and yeasts, which displays no haemolytic activity. Temporin-SHf was first isolated from the skin of the frog Pelophylax saharica and is a member of the temporin family of AMPs. Temporins are a large family of short, linear, AMPs produced in the skin of frogs belonging to Rana species, but are also found in wasp venom. Temporin-SHf is the smallest natural linear AMP found to date and has a highly hydrophobic sequence (75%) plus the highest percentage of phenylalanine residues of any known peptide (50%).Temporin-SHf works by disrupting the acyl chain packing of anionic lipid bilayers, causing cracks and microbial membrane disintegration through a detergent-like effect. Temporin-SHf is a promising candidate for the development of a new class of anti-microbial drugs.Couleur et forme :PowderMasse moléculaire :1,075.3 g/molTAT-CHN9 (C-ter)
Trans-activator of transcription protein (Tat) (47-57) is a cell penetrating cationic peptide derived from the N-terminus of the Tat protein from the human immunodeficiency virus (HIV). Chimerin 1, (CHN1) is a GTPase activating protein specific for RAC GTP-binding proteins, expressed primarily in the brain. CHN1 is involved in signal transduction and is a direct effector of proteins involved in axon guidance. CHN1 is transferred to the plasma membrane and negatively regulates Rho-family small GTPases RAC1 and CDC42, to cause morphological changes to axons by pruning the ends of axon dendrites. As a cell penetrating peptide (CPP) TAT aids in the cellular uptake of molecules. TAT (47-57) can be used to deliver proteins, fluorophores, chelators and DNA to target cells.Masse moléculaire :2,644.6 g/molAc-Arg-Gly-Lys(Ac)-AMC
Histone deacetylases (HDACs) are a family of enzymes which are highly evolutionary conserved across all eukaryotes. HDACs modify histones by removing acetyl groups from the tail regions. Histone deacetylation is generally associated with reduced gene expression due to a more compact chromatin state less accessibility for transcription factors (TFs). HDACs are essential for many physiological processes including development and cellular homeostasis. They also play an important role in disease states, including neurodegenerative disorders, genetic diseases and cancers.This peptide is the fluorogenic substrate for assaying histone deacetylase (HDAC) activity in a two-step enzymatic reaction. The assay consists of the initial lysine deacetylation by HDAC followed by the release of the fluorescent group by trypsin. Fluorescence can be detected upon fluorophore release.Masse moléculaire :600.3 g/molH-PIIHFGSDYEDR^-OH
Peptide H-PIIHFGSDYEDR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.LCBiot-KEELDKYFKNHTSPDVDLG-OH
Peptide LCBiot-KEELDKYFKNHTSPDVDLG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Setmelanotide
Pro-opiomelanocortin (POMC)-derived peptides act on neurons expressing the Melanocortin 4 receptor (MC4R) to reduce body weight. Setmelanotide is a highly potent MC4R agonist that leads to weight loss in diet-induced obese animals and obese individuals with complete POMC deficiency.The endogenous ligand alpha-melanocyte-stimulating hormone (alpha-MSH) for MC4R has been shown to have a much lower affinity than Setmelanotide, explaining some of the drug's potency. Administration of Setmelanotide to wildtype mice resulted in significant weight loss while MC4R knockout mice fail to respond. Setmelanotide is in numerous clinical trials and shows promising results. Patients with POMC defects upstream of MC4R show more significant responses to treatment than those with MC4R deficiency or obese controls.Masse moléculaire :1,117.34 g/molH-GMNYLEDR^-OH
Peptide H-GMNYLEDR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-LVVVGACGVGK^-OH
Peptide H-LVVVGACGVGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Histone H3 (1-22) K4Me3-Biotin
Histone H3 (1-22) K4Me3 is derived from Histone 3 (H3) which is one of the four core histones (H2A, H2B, H3 and H4) fundamental in compacting eukaryotic DNA into the nucleosome. The nucleosome arises when 147 base pairs of DNA wrap around a H3-H4 tetramer and two H2A-H2B dimers, forming the histone octamer core. Both H4 and H3 are highly conserved and perform roles in binding to segments of DNA which enter and leave the nucleosome and in chromatin formation. Similar to the other core histone, H3 has a globular domain and a flexible N-terminal domain, 'histone tail' which can undergo modifications such as acetylation, methylation, phosphorylation and ubiquitination. Due to histones containing a large number of lysine and arginine residues they have a positive net charge which interacts in an electrostatic manner with the negatively charged phosphate groups in DNA. The transcriptional activation or silencing of the chromatin is controlled by ATP-dependent chromatin remodelling factors and histone modifying enzymes which target histone proteins. Both processes function to alter the positioning of the nucleosome, allowing the DNA it to be either available or inaccessible to the transcription machinery.Another modification process histones can undergo is biotinylation where the covalent attachment of a biotin molecule is catalysed by the enzyme biotinidase. This cleaves biocytin to generate a biotinyl-thiester intermediate. The biotinyl can then be transferred onto the histone lysine ɛ-amino group which in this case it is covalently attached to Histone 3. Overall the biotinylation sites identified in histone 3 are: K4, K9 and K18. The presence of biotinylated histones have been detected in human cells such as lymphocytes and lymphomas.Lysine 4 of H3 (1-22) has been tri-methylated.Masse moléculaire :2,851.7 g/molβ-Amyloid (11-20) Human
Amyloid β-peptide (Aβ) has been identified as the key subunit of the extracellular plaques found in the brains of patients with Alzheimer's disease (AD) and Down's syndrome (DS). Aβ has therefore been extensively studied as a potential target for treatment of AD. Aβ is formed from the cleavage of the large, transmembrane protein APP (amyloid precursor protein). Cleavage of APP by β- and then γ-secretases results in the formation of Aβ. Aβ can aggregate to produce amyloid-β oligomers, which are thought to be highly neurotoxic. Over time Aβ can further aggregate to produce the characteristic senile plaques present in AD and DS. Aβ can be degraded by enzymes such as neprilysin, insulin degrading enzyme or endothelin converting enzyme. At physiological levels Aβ may be involved in controlling synaptic activity and neuronal survival.Masse moléculaire :1,283.48 g/molH-FVNEEAL^R-OH
Peptide H-FVNEEAL^R-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-VVSVLTVLHQDWL^NGK^-OH
Peptide H-VVSVLTVLHQDWL^NGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Calcitonin, Salmon
Calcitonin is a peptide hormone excreted by the thyroid parafollicular cells to regulate calcium and phosphorus levels. Calcitonin acts in opposition to parathyroid hormone (PTH) and vitamin D. Calcitonin functions by inhibiting osteoclast activity in the bones preventing calcium release- there is also inhibition of renal tubular cell reabsorption of calcium and phosphate, so they are excreted preventing a rise in levels.Calcitonin is used for as marker for detection and prognosis of nodular thyroid diseases. Medullary thyroid cancer is one example of the malignant parafollicular cells detectable with the assay, as they present with an increased calcitonin level even at an early stage.Since the discovery of calcitonin over 50 years ago the salmon sourced peptide has been used in numerous treatments including bone metastases, Paget disease, hypercalcaemia, and postmenopausal osteoporosis. The salmon calcitonin has been shown to be equivalent to human form but more active and can be synthetically generated.Masse moléculaire :3,429.7 g/molCyclo(-Met-Pro)
CAS :Cyclo(-Met-Pro) is a synthetic antioxidant that inhibits the proliferation of cancer cells. Cyclo(-Met-Pro) binds to the reactive oxygen species (ROS), such as hydroxyl, alkoxy, and peroxyl radicals, in the cell and prevents them from damaging DNA. Cyclo(-Met-Pro) also inhibits the generation of ROS by reacting with metal ions, such as iron and copper. This compound has been shown to have an effect on human cells by inhibiting the proliferation of cancer cells. Cyclo(-Met-Pro) is synthesized by reacting methylamine with cyclopentadiene in sodium hydroxide solution or hydroxide solution. The synthesis can be monitored using spectrometry analyses.Formule :C10H16N2O2SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :228.31 g/molHLA leader peptide LIL
Peptide H-VMAPRTLIL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
HXB2 gag NO-79/aa313 - 327
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolMasse moléculaire :1,761 g/molH-ALDLLDK^-OH
Peptide H-ALDLLDK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-FTITAGSK^-OH
Peptide H-FTITAGSK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-SALVLQYLR^-OH
Peptide H-SALVLQYLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Fluor-AEEEIYGEFEAKKKK-OH
Peptide Fluor-AEEEIYGEFEAKKKK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Ac-SWFR-NH2
Peptide Ac-SWFR-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.(D-Pro7)-Angiotensin I/II (1-7)
The renin angiotensin system (RAS) consists of many angiotensin peptides involved in regulating functions such as blood pressure, cardiovascular function and energy balance. RAS activity is elevated in obesity and RAS is widely studied in relation to lifestyle-related diseases.Angiotensin 1-7 (Ang-(1-7)) is a component of the RAS. Ang-(1-7) is produced by angiotensin-converting enzyme 2 (ACE2), from the angiotensin II (Ang-II) peptide, as well as by prolylendopeptidase (PEP) and neutral endopeptidase (NEP) which produce Ang1 7 directly from angiotensin I (Ang-I).Ang-(1-7) broadly opposes Ang-II actions. Ang-(1-7) has vasodilatory and anti-oxidative effects, and exerts protective actions in hypertension, diabetes, and other cardiovascular disorders, Ang-(1-7) therefore represents a promising therapeutic target for cardiovascular and metabolic diseases. Ang (1-7) exerts its actions via its G-protein-coupled receptor, Mas. This novel arm of the RAS has effects that counterbalance those mediated by the classical ACE/Ang-II pathway.The C-terminal proline fro this peptide is in the D enantiomer.Couleur et forme :PowderMasse moléculaire :898.5 g/molCys(Npys)-TAT (49-57), FAM-labeled
Cys- Activated and FAM-labeled TAT for Cargo Conjunction. This product is available as a trifluoroacetate saltFormule :C88H136N36O20S2Degré de pureté :Min. 95%Masse moléculaire :2,082.42 g/molGalanin (2-12) acid
Galanin is a neuropeptide synthesised and released by the brainstem locus coeruleus (LC). Galanin is expressed in most LC neurons in rodents and humans. Galanin has been shown to inhibit LC activity by hyperpolarising LC neurons, suppressing their spontaneous firing rate, and enhancing alpha2-adrenergic receptor-mediated negative feedback. Galanin is also a potent trophic and neuroprotective factor throughout the nervous system.Galanin is widely distributed from the central nervous, peripheral, and endocrine systems. Galanin's overarching function is as an inhibitory, hyper-polarizing neuromodulator for classical neurotransmitters like acetylcholine and serotonin. Galanin interacts with 3 receptor subtypes, GalR1-3 G protein-coupled receptors which are inserted into the plasma membrane. GalR1 is believed to activate a Gβγ pathway to regulate MAPK activation. GalR2 can also activate the MAPK pathway, but unlike GalR1, there is detectable inositol phosphate production. GalR3 is associated with the Galphai/o pathway. Activation of the receptor leads to a cellular influx of K+. Each receptor has been associated with neurological diseases such as GalR3 and epilepsy.Some N-terminal fragments naturally occur in vivo but their relevance is unclear. The physiological relevance of the galanin fragment (2-12) and its affinity to the various GalR receptors has yet to be made clear. Binding assays and displacement assays in rat brain tissue have been performed with similar N-terminal galanin fragments to try and elucidate their function. . The use of N-terminal fragments such as galanin (2-12) can help clarify the function of full-length galanin. This may highlight new agonists/antagonists for the galanin GalR receptors that can be putative therapeutic targets for treatments of conditions such as cardiovascular disease.NMR has used this galanin fragment (2-12) to help characterise the structure of galanin. It shows the critical residues Tyr(9), Leu(10), and Leu(11) for interaction with the galR receptors. They cluster together as collapsed hydrophobic residues irrelevant to forming higher-order structures.Masse moléculaire :1,193.6 g/molH-YQTFFNPRT^FGSGE-OH
Peptide H-YQTFFNPRT^FGSGE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Fluor-RRGG-OH
Peptide Fluor-RRGG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-LRRQHAR^ASHLGLAR-OH
Peptide H-LRRQHAR^ASHLGLAR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
[5-FAM]-PTH (1-34)
PTH 1-34, is a biologically active peptide fragment of parathyroid hormone (PTH). PHT 1-34 has been shown to enhance bone fracture healing by promoting osteogenesis. PTH 1-34 also has chondrogenic properties.PTH is an 84-amino-acid polypeptide hormone (PTH 1-84) which is secreted by the parathyroid glands along with its fragments (such as PTH 1-34 and PTH 7-84). PTH increases calcium and decrease phosphate levels in the blood and the abundance of PTH-derived peptides is regulated by blood calcium levels. PTH inhibits the bone growth-promoting activity of osteoblasts and induces osteoclasts to resorb bone and release calcium and phosphate ions into the blood. PTH binds to and activates the receptor parathyroid hormone receptor 1 (PTHR1). PTHR1 is a G-protein-coupled receptor (GPCR) which regulates mineral ion homeostasis, bone turnover and skeletal development.It contains 5-Carboxyfluorescein (5-FAM), a widely used green fluorescent tag.Couleur et forme :PowderMasse moléculaire :4,473.2 g/molH2N-Gly-Pro-Leu-Gly-Val-Arg-Gly-Cys-COOH
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFormule :C31H55N11O9S1Masse moléculaire :757.9 g/molH-CLAVEEVSL^-OH
Peptide H-CLAVEEVSL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
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