Peptides

Peptide H-DCL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Body Protecting Compound (BPC) 157 is a pentadecapeptide gut peptide with free radical scavenging activity.  As a gastric juice pentadecapeptide fragment, BPC 157 stimulates nitric oxide synthase generation, offering significant gastric cytoprotection. It has been shown to heal lesions in experimental models of bowel disease, Unlike many other peptides, BPC 157 effectively acts without a carrier, notably aiding in muscle healing, such as in the treatment of gastrocnemius muscle complex injuries.  BPC 157 is also an anti-inflammatory agent that has been shown to have clinical relevance in patients with congestive heart failure. BPC 157 has been shown to inhibit inflammation by blocking the production of proinflammatory mediators such as prostaglandins and leukotrienes. It also suppresses the production of proinflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). BPC 157 also downregulates genes that are involved in liver fibrosis, which may account for its efficacy in patients with liver cirrhosis. BPC 157 increases the production of hepatocyte growth factors (HGFs), which stimulate cell proliferation and promote tissue repair. It also upregulates genes involved in wound healing. Additionally, BPC 157 displays antianxiety and antidepressant effects. At the cellular level, it fosters proliferation, migration, and tube formation in human umbilical vein endothelial cells by activating ERK1/2 phosphorylation.

H-Phe-Ile-Arg-Gly-Gly-Met-Tyr-Glu-Gly-Lys-Lys is a peptide that has biological activity. It is a member of the class of Biologically Active Peptides, which are biochemicals that have been shown to have cardioprotective effects. This peptide was found to reduce cardiac injury and dysfunction in animal models of myocardial infarction.

Boc-Leu-Gly-Arg-AMC acetate salt is a potential drug target for leishmaniasis. It inhibits the growth of Leishmania by binding to the 17β-estradiol receptor and inhibiting protein synthesis. This drug also has a hydrolytic activity against proteins, which is activated by an acidic environment. It has been shown to inhibit the growth of bacteria including Staphylococcus aureus and Chlamydia pneumoniae by inhibiting urokinase-type plasminogen activator (uPA) and serine protease activities. Boc-Leu-Gly-Arg-AMC acetate salt has also been shown to inhibit cellular proliferation in cancer cells.

Abz-Phe-Arg-Lys(Dnp)-Pro-OH trifluoroacetate (ABA) is a low potency activator of the endogenous angiotensin system, with no known clinical use. ABA has been shown to activate the endogenous angiotensin system in vivo in rats and humans. It has also been shown to increase blood pressure in rats by activating the renal sympathetic nervous system. The activation of this system may be due to its ability to release neutrophil chemotactic factor from adipose tissue, increasing the number of neutrophils that contribute to inflammation through their release of reactive oxygen species. The mechanism underlying this activation is unknown, but may involve an interaction with enalaprilat, a potent inhibitor of angiotensin converting enzyme (ACE), or adipose tissue lipolysis.

H-Trp-Phe-OH is a chromatographic, ligand, and mass spectrometric compound that has a red shift in its fluorescence spectrum. It has been shown to have anti-cancer properties by blocking the cell cycle at the G2/M phase. The red shift of the fluorescence spectrum is due to the presence of two isomeric forms that have different optical properties. H-Trp-Phe-OH has been analysed for its effects on cancer cells and was found to inhibit growth and induce apoptosis in mononuclear leukemia cells.

Peptide H-ARGYISTRVEMGEAA-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.