Peptides

Custom research peptide; min purity 95%.

<p>MAL-dPEG®12-TFP Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. MAL-dPEG®12-TFP Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

Custom research peptide; min purity 95%.

<p>Portion of EBV LMP2A</p>

Lipoprotein Lipase is a type of enzyme that is involved in the breakdown of fats (lipids) into smaller components like free fatty acids and glycerol. This enzyme is made up of two subunits, an alpha subunit and a beta subunit. The alpha subunit has four domains, while the beta subunit has three domains. Lipoprotein Lipase is found in human plasma and tissue, where it performs its function by attaching to the surface of cells or lipoproteins and releasing free fatty acids. It also binds to cholesterol, which may be due to its ability to form hydrogen bonds with this molecule.

<p>SPDP-dPEG®4-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. SPDP-dPEG®4-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Standard for use in proteomics studies</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Heat Shock Protein 70kDa is a protein that belongs to the heat shock protein family. It is an important regulator of the intracellular proteolytic and metabolic pathways. Heat Shock Protein 70kDa has been shown to be involved in the regulation of ion channels, receptor-ligand interactions, and protein synthesis. It also plays a role in cell cycle regulation, apoptosis, and other cellular processes. The recombinant human HSP70KD protein is produced in E. coli and has been purified by a series of chromatographic steps. This product is provided as lyophilized powder in 100% pure water with no additives or preservatives.</p>

<p>M CSF Mouse is a research tool that is an activator, ligand, and receptor in cell biology. It is a cell-surface protein that binds to the receptor for macrophage colony-stimulating factor (M-CSF). M-CSF Mouse stimulates the proliferation of hematopoietic progenitor cells and enhances their differentiation into macrophages. This product has been extensively used as an antibody with high purity. M CSF Mouse has also been shown to be a natural inhibitor of ion channels, which may be due to its ability to bind to voltage-gated potassium channels.</p>

Custom research peptide; min purity 95%.

<p>Streptavidin-NC is a recombinant protein that is used in immunoassays. It binds to biotin and can be used as an alternative to the antigen-antibody reaction. Streptavidin-NC binds to the biotinylated antigen at the same time as it binds to the specific antibody, forming a sandwich complex. Streptavidin-NC has been shown to be more sensitive than antibodies in cardiac muscle and skeletal muscle immunoassays, with better specificity for cardiac troponin I and T than monoclonal antibodies. The molecular mass of this protein is about 50000 Da, which corresponds to a chain with about 500 amino acids.</p>

<p>A TIMP1 Heavy Tryptic Peptide Standard for protein identification and quantitation studies. TIMP1, also known as TIMP metallopeptidase inhibitor 1 is an inhibitor of matrix metalloproteinases, which are enzymes that break down the extracellular matrix. It has also been associated with cell proliferation promotion and may have a role in apoptosis.</p>

<p>Bromoacetamido-dPEG®23-Azide is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Bromoacetamido-dPEG®23-Azide is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

Custom research peptide; min purity 95%.

<p>Gly-Gly-Tyr-Arg acetate dihydrate is a tetrapeptide and a ligand for the enzyme papain. It binds to the active site of papain and inhibits its proteolytic activity. Gly-Gly-Tyr-Arg acetate dihydrate has been shown to be an inhibitor of trypsin and chymotrypsin, but not other proteases. It has also been shown to inhibit the polymerase chain reaction and RNA synthesis in vitro.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Carboxyfluorescein-dPEG®24-Amido-dPEG®24-DSPE is a PEG compound containing a fluorescein dye used for tagging biomolecules, and serving as fluorescent probe for bioimaging applications.</p>

<p>H-Gln-2-ClTrt-Resin is a resin that consists of polystyrene crosslinked with divinylbenzene. It is used in peptide synthesis to provide amino acids and building blocks for the synthesis of peptides and proteins. This resin can be used as a component in the production of amines, alcohols, thiols, and other organic compounds. The crosslinking agent in this resin is divinylbenzene (DVB).</p>

Custom research peptide; min purity 95%.

<p>Eledoisin-related peptide is a research tool that can be used to study the activation of G protein-coupled receptors. It is a ligand and an activator of the human beta-adrenergic receptor. Eledoisin-related peptide binds to the beta2-adrenergic receptor with high affinity, but does not activate the receptor. Instead, it inhibits the binding of other ligands such as epinephrine and norepinephrine to their respective receptors. Eledoisin-related peptide has been shown to inhibit ion channels in cell biology studies. This peptide has also been shown to bind to antibodies and interact with proteins in pharmacological studies.</p>

Custom research peptide; min purity 95%.

<p>Bromoacetamido-dPEG®4 -TFP Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Bromoacetamido-dPEG®4 -TFP Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Soybean BBI is a protein that belongs to the family of ion channels. It is an activator of receptor-operated calcium channels, which are found in many types of cells and are involved in a variety of physiological processes. Soybean BBI has been shown to inhibit the activity of potassium channels, which help regulate the electrical activity in neurons. Soybean BBI can be used as a research tool for studying protein interactions and peptides. It has also been used as an antibody for Western blot analysis and immunocytochemistry techniques. This protein has a CAS number and is available at high purity.</p>

Custom research peptide; min purity 95%.

<p>IGHG1 MS Calibrator-5 is a calibrator for the IGHG1 tryptic peptide. It is used for the quantitative determination of Ig gamma-1 chain C region in proteomics and biologically active peptides.</p>

<p>ANP (human, 5-28) is a peptide that is used as a research tool for studying the function of ion channels. It is also an antibody that can be used to measure protein interactions. ANP (human, 5-28) has been shown to inhibit protein interactions with the receptor and ligand. This peptide has been shown to act as an activator at high concentrations and an inhibitor at low concentrations.</p>

<p>Atosiban is a drug that is used to prevent preterm labor in pregnant women. It works by inhibiting the release of oxytocin from the hypothalamus, which decreases contractions and relaxes the uterus. Atosiban has been shown to be effective in decreasing the incidence of preterm birth in women with bacterial vaginosis who are at high risk for preterm delivery (e.g., those with a history of preterm labor). Clinical trials have shown that it may also be useful as an adjunct therapy in treating women with unexplained infertility and recurrent pregnancy loss. The drug binds to receptors on cells, which inhibits the release of intracellular calcium, thus preventing contraction of uterine muscle cells. This effect can be reversed by administration of estradiol benzoate or other drugs that affect receptor activity. It is not known whether atosiban affects fetal development during pregnancy or if it causes any effects on the mother's heart rate or body mass index after childbirth.</p>

<p>Bis-dPEG®4-Acid is a PEG polymer categorised as homobifunctional PEG (X-PEG X). Used as a linker, bis-dPEG®4-Acid is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.</p>

<p>Bromoacetamido-dPEG®4-Amido-DBCO is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Bromoacetamido-dPEG®4-Amido-DBCO is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>IL-1 beta is a cytokine, which belongs to the IL-1 family of cytokines. It is a proinflammatory cytokine that induces fever and pain, and stimulates the immune system. IL-1 beta binds to the IL-1 receptor, which is a member of the class 1 cytokine receptor family. The binding activates phospholipase A2 and protein kinase C, which leads to an increase in prostaglandin production by cyclooxygenase 2. IL-1 beta also has been shown to inhibit ion channel activity and calcium uptake in cells.</p>

<p>Antithrombin III heavy tryptic peptide standard for protein identification and quantitation studies. Antithrombin III is a glycoprotein found in blood plasma and is involved in the regulation of the coagulation process.</p>

<p>Monobiotin INSL4 is a biologically active peptide that belongs to the group of relaxins. It is an analogue of human relaxin and has been labelled with biotin for use in in vitro experiments.</p>

Custom research peptide; min purity 95%.

<p>This is a vivitide catalogue product. Please send your vivitide product enquiry to sales@vivitide.com for an up-to-date price and availability.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

Custom research peptide; min purity 95%.

Custom research peptide; min purity 95%.

Custom research peptide; min purity 95%.

<p>Custom research peptide; min purity 95%.</p>

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

Custom research peptide; min purity 95%.

Custom research peptide; min purity 95%.

Custom research peptide; min purity 95%.

Custom research peptide; min purity 95%.

Custom research peptide; min purity 95%.

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Phrixotoxin 3 is a neurotoxin that belongs to the class of bioconjugate chemistry. It has been shown to have inhibitory effects on voltage-dependent calcium channels in ganglion cells and on voltage-gated sodium channels in rat dorsal root ganglia. Phrixotoxin 3 has also been shown to bind to bacteria, including gram-negative bacteria, and to target complementarity regions. The amino acid composition of Phrixotoxin 3 is homologous with a region of the C3 protein, which is involved in the complement system. This neurotoxin can be used as a research tool for investigating the role of voltage-gated channels in pain pathways.</p>

<p>Tyrosinase protein:<br>Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV) is a human tyrosinase-derived (369-377) peptide by posttranslational conversion of the sequence YMNGTMSQV. Tyrosinase is an oxidase membrane-bound protein. Tyrosinase play a key role in the melanin synthesis pathway. Tyrosinase is presented on the surface of HLA-A*02:01 melanomas and also expressed in melanocytes. Tyrosinase has been still suggested to be a tumor antigen and might be implicated in improvement of immunotherapeutic strategies such as for efficient anticancer vaccine development.<br>Applications of Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV):<br>Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV) is used to stimulate specific cytotoxic T lymphocytes (CTL) in PBMCs and then to analyze CTL response especially the cytokine production by ELISPOT assay. Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV) is also involved in experimental therapies of metastatic melanoma by allogeneic hematopoietic stem cell transplantation. In fact, cytotoxic T cells were generated from peripherical blood mononuclear cells (PBMCs) of HLA-A*02:01 healthy donors after being stimulated by injection of Asp371 antigen (2). This strategy raises issues which concern the graft versus tumor (GvT) effect and graft versus host disease (GvHD).</p>

<p>Custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

Custom research peptide; min purity 95%.

Custom research peptide; min purity 95%.

Magainin-1 is a 23-amino acids peptide which belongs to the magainin peptide family. Magainins are antibiotic peptides with antibacterial, antiviral and antifungal activities. These peptides cause perturbation of membrane functions responsible for osmotic balance. Magainin-1 carries out its antibacterial activity by folding to an amphiphilic helix to interact specifically with lipidic bilayer, resulting in a permeability change. Magainin-1 has broad-spectrum, non-specific activity against a wide range of micro-organisms including viruses as HSV-1 and HSV-2, gram-positive and gram-negative bacteria, protozoa, yeasts and fungi. Magainin-1 may also be hemolytic and cytotoxic to cancer cells. Besides its antimicrobial activity, Magainin-1 presents an antifungal activity against some pathogens such as Candida Albicans with a antifungal activity of 4.15 uM. Recently, it has also been shown that magainin-1 can induce apoptosis of some leukemia cells at a concentration of 10 to 50 nM.

<p>H-Thr-Glu-OH is a nucleotide that is a component of RNA. It is one of the 20 natural amino acids and it is found in proteins as well as in RNA molecules. H-Thr-Glu-OH can be synthesized by hydrolysis of proteins with an enzyme called glutamic acid hydrolase. H-Thr-Glu-OH has been shown to have a high affinity for lysine, which has been shown to be required for the enzymatic activity of many protein enzymes. This amino acid can also be found in large quantities in cheese, soy sauce, and yogurt.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Please enquire for more information about H-Asp-Val-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Custom research peptide; min purity 95%.

<p>Please enquire for more information about H-Asp-Leu-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Big ET-2 (human, 22-37) Antiserum is an antibody that reacts with the Big ET-2 (human, 22-37) peptide. It can be used as a research tool to study the function of Ion channels, Life Science, Receptor, Ligand and Protein interactions. The high purity of this antibody makes it a valuable resource for drug development.

<p>Anti-Preprorenin (21-64) is a peptide inhibitor of renin. It has been shown to inhibit the activity of renin, an enzyme that plays a key role in regulating blood pressure. Renin cleaves a prohormone called angiotensinogen into angiotensin I, which is then converted to angiotensin II by the angiotensin-converting enzyme. Angiotensin II causes vasoconstriction and stimulates the secretion of aldosterone from the adrenal glands. Anti-Preprorenin (21-64) inhibits renin by binding to its active site and preventing it from converting angiotensinogen to angiotensin I. This product can be used in research as an activator or ligand for receptor or antibody studies.</p>

Custom research peptide; min purity 95%.

Custom research peptide; min purity 95%.

Monobiotin INSL5 is a peptide that is biologically active and is obtained from the New England Peptide Company. Monobiotin INSL5 has shown to be an antagonist of the insulin-like growth factor II receptor and may have potential as a therapeutic agent for diabetes mellitus.

Apolipoprotein A1 heavy tryptic peptide standard for protein identification and quantitation studies. Apolipoprotein A1 is a structural component of high density lipoprotein (HDL) and is involved in cellular cholesterol homeostasis and reverse cholesterol transport.

<p>3x DYKDDDDK peptide, also called 3x FLAG peptide, is a 23 aa length peptide used for the competitive elution of DYKDDDDK-tag fusion proteins (with excess of free 3x DYKDDDDK peptide) under non-denaturing conditions, especially when a DYKDDDDK-tagged protein is sensitive to low pH.</p>

<p>Elafin is a peptide that belongs to the family of activators. It is a member of the human elafin family that activates neutrophil elastase, which belongs to the group of serine proteases. Elafin has been shown to inhibit the activity of ion channels and receptor-ligand interactions in cell biology studies. Elafin also binds to antibodies and is an inhibitor for protein interactions. Elafin has been shown to be a caspase-3 substrate, but its role in apoptosis is not yet clear.</p>

ALPHA FACTOR SIGNALING PEPTIDE

This HER-2 Light Tryptic Peptide standard can be applied to protein identification and quantitation studies. HER-2 is the human epidermal growth factor receptor 2, which has tyrosine kinase activity and is involved the control of epithelial cell growth and differentiation. The overexpression of HER2 has been implicated with adenocarcinomas such as cervix, lung, ovary and breast.

<p>1-Deoxyfructosyl-Val-His-[D7]Leu-Thr-Pro-Glu is a research tool that belongs to the group of activators. It activates receptors and ion channels. This product has been shown to inhibit cell proliferation, peptide binding and protein interactions. 1-Deoxyfructosyl-Val-His-[D7]Leu-Thr-Pro-Glu is a high purity and potent inhibitor of protein interactions with pharmacological applications.</p>

TTR MS Calibrator is a research tool that is used to calibrate the mass spectrometer for TTR peptide analysis. It has an excellent purity and is provided as a lyophilized powder. This calibrator contains high-quality TTR peptides with a low level of impurities. The product can be used for pharmacological or proteomic studies, as well as other research applications.

<p>Bis-dPEG®4-TFP Ester is a PEG polymer categorised as homobifunctional PEG (X-PEG X). Used as a linker, bis-dPEG®4-TFP Ester is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.</p>

<p>I-TAC is a chemokine that is expressed in high amounts in the human blood and leukocytes. It also has been shown to be an inducible chemoattractant for leukocytes. I-TAC is a member of the CXC family of chemokines, which are small proteins that act as chemoattractants for cells of the immune system. I-TAC has been shown to attract neutrophils, monocytes, and T cells by binding to their receptors.</p>

<p>DOTA-tris(Acid)-Amido-dPEG®23-Maleimide is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. DOTA-tris(Acid)-Amido-dPEG®23-Maleimide is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>The Glucagon-HS ELISA (Kit) is a sandwich ELISA for the quantitative measurement of human glucagon in serum. The kit contains an antibody specific to human glucagon, and a detection antibody that has been pre-coated onto the wells of the microtiter plate. Standards are provided in order to generate a standard curve. A sample is added to each well and any human glucagon present will bind to the antibody. After incubation and washing, a substrate solution is added which will react with the bound human glucagon, resulting in a color change proportional to the amount of human glucagon present in the sample. The color change is measured by absorbance at 450 nm and compared against known concentrations of human glucagon on a standard curve.<br>br&gt;br&gt;<br>The Glucagon-HS ELISA (Kit) provides an accurate means for measuring serum levels of human glucagon in clinical, research, or veterinary settings. It can be used as a diagnostic aid</p>

<p>MOCAc-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-NH₂ is a peptide that can be used as a research tool to study protein interactions and receptor function. MOCAc-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-NH₂ inhibits the ion channels, which are involved in the transmission of nerve impulses. The peptide has been shown to bind with high affinity to the nicotinic acetylcholine receptor (nAChR) and may be used as a ligand for this receptor.</p>

<p>Insulin is a peptide hormone that regulates blood glucose levels and promotes the uptake of glucose by cells. Insulin is produced in the pancreas and consists of 51 amino acids. It has a molecular weight of 5808 Da and consists of two chains, A (21-amino acid) and B (30-amino acid). The A chain is primarily responsible for insulin's activity, while the B chain improves its stability. Insulin binds to receptors on the cell surface, which activates an intracellular signaling cascade that subsequently leads to changes in gene expression. Insulin has been widely used as a research tool to study protein interactions, ligand binding, receptor activation, ion channel modulation, antibody production, and other cellular processes. Insulin I (Rat) is isolated from rat pancreas using a purification process that yields high purity insulin with minimal contaminating proteins or peptides. This product can be used in life science research applications such as pharmacology studies and antibody production.<br>This product has the three letter code: A-chain: Gly-Ile-Val-Asp-Gln-Cys-Cys-Thr-Ser-Ile-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn ; B-chain: Phe-Val-Lys-Gln-His-Leu-Cys-Gly-Pro-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ser has the disulfide Bonds: CysA6-CysA11, CysA7-CysB7, and CysA20-CysB19 and is available as a 50µg vial.</p>

<p>m-dPEG®12-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®12-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>MAL-dPEG®4-Glu(OH)-NH-m-dPEG®24 is a peptide containing polyethylene glycol (PEG) as spacer to alter their pharmacokinetic properties and pharmodynamics.</p>

<p>Galanin is a peptide that is involved in the regulation of many physiological processes, including the regulation of food intake, water balance, and pain perception. The rat galanin antiserum reacts with both human and rat galanin. Galanin is a member of the family of G protein-coupled receptors (GPCRs).</p>

<p>FGF 8 is a protein that is involved in the regulation of cell growth, differentiation and survival. It can bind to FGF receptors on cells, which triggers a signal transduction pathway. The activation of this pathway leads to the inhibition of GSK3β activity and the activation of Akt. FGF 8 also binds to FGFR4, which activates phospholipase C (PLC) and increases intracellular Ca2+. This leads to the activation of PKC and calpain, which then activate nitric oxide synthases (NOS). Activation of NOS leads to increased production of nitric oxide, which causes vasodilation.</p>

<p>Carboxyl-dPEG®4-(m-dPEG®11)3 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Carboxyl-dPEG®4-(m-dPEG®11)3 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>TentaGel; is a gelatinous resin, an important support for solid phase synthesis. TentaGel; resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol) as shown below. The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix.<br>These resins are designed for single bead synthesis and single bead analysis (mean particle size 280-320 µm: capacity 02-03 meq/g) and substitutional functional group: -NH.</p>

<p>Fmoc-Asn[per-O-Boc-(Fucα1-6GlcNAcß)] is a glycopeptide that is synthesized with an N-linked glycosylation. This product is a disaccharide that contains two hydroxy groups and one hydroxy group. The peptide bond has been shown to be stable in both acidic and basic conditions. It can be used for peptide synthesis and has an affinity for the sugar moieties of proteins.</p>

<p>Suc-Ala-pNA is a molecule that is composed of alendronic acid, which is a prodrug that has been conjugated to polyethylene glycol and polyaspartic acid. The pNA moiety in the molecule is capable of penetrating the mucosal membrane and can be cleaved by aminopeptidase and peptidase to release active alendronic acid. The mucoadhesive polymers increase the permeability of the molecule, while the spacer group increases its stability. Suc-Ala-pNA has been shown to have a high affinity for bone mineralization, as it reacts with bone mineral surfaces to form a covalent bond. This reaction mechanism leads to increased bone mineralization, which may help treat osteoporosis.</p>

<p>Anti VIP (Human, Porcine) Serum is a research tool for the study of protein interactions. It inhibits the binding of VIP to its receptor. Anti VIP (Human, Porcine) Serum is an inhibitor and activator of ion channels. It has been shown to bind to a wide variety of receptors and ligands, including those involved in cell biology and pharmacology. This product is highly purified and can be used in life science research as well as antibody production.</p>

<p>Centromere protein B (CENP-B) is a protein that belongs to the histone H3 family. It is one of the proteins involved in regulating chromosome segregation during mitosis and meiosis. CENP-B has been shown to be involved in the activation of kinetochores, which are structures on the surface of chromosomes that attach to microtubules and help with mitotic chromosome movement. Centromere protein B can also be used as a ligand or receptor, or a tool for cell biology, immunology, and pharmacology research.</p>

<p>Insulin-like 4 (INSL4) is a growth factor that promotes the proliferation and differentiation of primary cells, including decidual cells. It has been shown to enhance the expression of matrix metalloproteinase (MMP), an enzyme that breaks down extracellular matrix proteins. INSL4 also reduces the production of IGFBP-2, a protein that inhibits insulin-like growth factor 1 (IGF1). INSL4 has been shown to inhibit cancer cell proliferation in transfection experiments and clinical data. It has also been shown to have an inhibitory effect on cancer cells expressing insulin-like growth factor type 3 receptor.</p>

<p>Anti ATP Receptor P2X4 (370-388) (Rat) Serum is an antibody that binds to the extracellular domain of the P2X4 receptor. The antibody has been shown to inhibit the ATP-induced increase in intracellular calcium levels. It is a research tool for studying the function of P2X4 receptors and ion channels. It is also used as an inhibitor in pharmacology, cell biology, and protein interactions. Anti ATP Receptor P2X4 (370-388) (Rat) Serum has a CAS number of 12056-07-8.</p>

<p>Endokinin C is a peptide that is an inhibitor of protein interactions. It has a CAS number of 52783-30-4. Endokinin C has been shown to have the ability to inhibit the activity of ion channels, such as potassium channels, sodium channels, and calcium channels. This peptide also activates ligands and receptors in the body, including epidermal growth factor receptor (EGFR), insulin-like growth factor receptor (IGF1R), and nerve growth factor receptor (NGFR). Endokinin C is purified from human urine. It has high purity with a protein content of less than 5%.</p>

<p>Porcine follicle stimulating hormone (FSH) is a peptide hormone that belongs to the group of gonadotropin hormones. It is produced in the anterior pituitary gland and stimulates ovarian activity, as well as follicular growth in females. FSH has been shown to stimulate cell factor, an enzyme involved in erythropoiesis, through a dinucleotide phosphate-dependent polymerase chain reaction. FSH also has been shown to increase estradiol benzoate levels and disulfide bond formation. Porcine FSH can be used for in vitro fertilization by stimulating the growth of human egg cells in culture with human serum or sephadex g-100.</p>

<p>Substance P (4-11) is a peptide that is a member of the tachykinin family. This protein is released by neurons and acts as a neurotransmitter in the brain, where it binds to neurokinin receptors. The structure of Substance P (4-11) has been determined using high-resolution nuclear magnetic resonance spectroscopy and X-ray crystallography. It contains four tryptophans, seven prolines, and nine amino acids in total. Substance P (4-11) has been shown to bind to neurokinin receptors, which are ligand-gated ion channels found on the surface of cells. Binding of this protein leads to an increase in cell permeability through ion channels and causes an increase in intracellular calcium levels.</p>

<p>GRP is a member of the G protein-coupled receptor family. GRP is an endogenous ligand for the GPCR, with binding affinity to GRP receptors. Activation of GRP receptors results in inhibition of cAMP production and activation of K+ channels. Anti-GRP serum is a research tool that can be used to identify and characterize GRP receptors by blocking their ability to bind endogenous ligands. This inhibitor has been shown to inhibit peptides that are inhibitors for ion channels, such as the nicotinic acetylcholine receptor and the glycine receptor. The anti-GRP serum also binds to antibodies raised against the peptide sequence of GRP, which may be used to identify these proteins in immunoblots or Western blots.</p>

<p>Pyr-Pro-Val-pNA is a research tool that can be used to study protein interactions. It is an activator ligand that binds to the receptor and can activate ion channels. Pyr-Pro-Val-pNA has been shown to inhibit the binding of antibodies to their antigen. This ligand can be used as a pharmacological agent for the treatment of various diseases, including cancer.</p>

<p>This resin is specially designed for difficult and long sequences.<br>TentaGel is a gelatinous resin, an important support for solid phase synthesis. TentaGel resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol) as shown below. The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000.<br>This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix. Particle size 90 µm; capacity: 0.18-0.22 meq/g.<br>Substiution Functional Group: -O-CH2-CH2-NH2</p>

<p>m-dPEG®48-CO(CH2)3-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®48-CO(CH2)3-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>TentaGel H RAM is a building block for peptide synthesis and a resin for peptide synthesis. It is made of 3-hydroxypropyl methacrylate (HPM) and bis-acrylamide (BAM) in a ratio of 1:1. TentaGel H RAM is used as an alternative to polystyrene, which has been used as the base resin for peptide synthesis.</p>

<p>FRETS-25Trp is a peptide that is used as a research tool for the study of protein interactions. It is an activator of ion channels and has been shown to bind to the receptor site of protein. FRETS-25Trp has also been shown to inhibit the interaction between ligands and receptors, which may be due to its ability to mimic the natural ligand or compete with it for binding sites. FRETS-25Trp is synthesized by solid phase peptide synthesis on a resin, which provides high purity and yields of up to 1 umol per reaction.<br>FRETS-25Trp (1 umol) (1umol) is CAS No. 120106-03-5 and Reagent No. F2204.</p>

<p>Prosaposin is a human, recombinant secretory protein that is produced by the freeze-drying of a lysosomal extract. It is used to treat cerebrospinal fluid that has been depleted of prosaposin. This protein functions as a linker and interacts with choline, glycosphingolipids, and phospholipids to form the myelin sheath in the central nervous system. Prosaposin can also be reconstituted with deionized water and aliquots containing 1 mg/mL of this protein are available for purchase.</p>

<p>NH2-dPEG®4-Glu(OH)-NH-m-dPEG®24 is a peptide containing polyethylene glycol (PEG) as spacer to alter their pharmacokinetic properties and pharmodynamics.</p>

<p>Please enquire for more information about Methoxytrityl-S-dPEG®12-Acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>IGF1 Rat is a recombinant IGF-1 receptor ligand that is a member of the insulin-like growth factor family. It activates the IGF-1 receptor and has been used as a research tool for studying protein interactions, such as those with G-protein coupled receptors and ion channels. The recombinant IGF-1 rat peptide is an excellent choice for pharmacological studies because it is highly purified and contains no contaminants.</p>

<p>Big Endothelin-3 (Rat, 1-41 Amide) is a precursor molecule of the Endothelin-3 (ET-3) peptide, that belongs to the large family of endothelin peptides which activate the G-protein coupled receptors ETA and ETB. However ET-3 has lower affinity for the ETA receptors compared to Endothelin-1 (ET-1) and Endothelin-2 (ET-2), whereas all three endothelins have similar affinity for ETB receptors. As ETB receptors make up around 90% of the endothelin receptors found in the cerebral cortex in humans, ET-3 can be nicknamed the ‘brain endothelin’. Also through ET-3’s activation of ETB receptors, ET-3 is involved in the development of the enteric nervous system which controls within the gut, blood flow, secretion and intestinal motility. This product has disulfide bonds between Cys1-Cys15 and Cys3-Cys11 and is available as a 0.1mg vial.</p>

<p>FRETS-25His is a synthetic peptide that can be used as a research tool for studying receptor-ligand interactions. FRETS-25His binds to the extracellular loop of the alpha subunit of the nicotinic acetylcholine receptor and inhibits its activity. This peptide is useful for pharmacology studies, such as those investigating the effect of various drugs on the human body. FRETS-25His is synthesized with high purity and has a CAS number: 90415-01-3. FRETS-25His can be used in cell biology studies to study protein interactions, such as those between ion channels and ligands.</p>

<p>The MAPK1, ERK2, PRKM1, PRKM2 MS Calibrator (25nmol) is a kit that contains the peptide sequences of three MAP kinases: MAPK1, ERK2 and PRKM2. The kit is used in the study of protein kinases and can be used as a calibration standard for Western blotting. It contains the tryptic peptides of MAP kinases and their corresponding molecular weight markers.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CDC45L antibody, catalog no. 70R-5557</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of UCHL5 antibody, catalog no. 70R-9729</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PLDN antibody, catalog no. 70R-2857</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of C14orf180 antibody, catalog no. 70R-6428</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of LEMD2 antibody, catalog no. 70R-6307</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of TCP11 antibody, catalog no. 70R-3458</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PCYT2 antibody, catalog no. 70R-2919</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of MBNL2 antibody, catalog no. 70R-9089</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CKR-2 antibody, catalog no. 70R-5967</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of FKBP4 antibody, catalog no. 70R-7828</p>