Peptides

Custom research peptide; min purity 95%.

<p>Custom research peptide; min purity 95%.</p>

Custom research peptide; min purity 95%.

MonoFITC RLN3 is a labelled form of relaxin that can be used to measure the clearance of relaxin in tissue culture. It can also be used for quantification and localization of peptide receptors in tissues.

<p>Amino-dPEG®24-Tris(-dPEG®24- Tris (m-dPEG®24)3)3 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Amino-dPEG®24-Tris(-dPEG®24- Tris (m-dPEG®24)3)3 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

IL-1α is a cytokine that belongs to the group of proinflammatory cytokines. It plays a role in the immune response and inflammatory reactions by inducing the synthesis of other cytokines, such as IL-6, IL-8, and TNF-α. IL-1α binds to its receptor on a cell surface and activates an intracellular signalling cascade. The binding of IL-1α to its receptor induces conformational changes in the receptor, which leads to activation of phospholipase C (PLC) and production of IP3. This process results in increased levels of calcium ions inside the cell and activation of protein kinases such as PKC, MAPKs and JNKs. This results in increased activity of enzymes such as cyclooxygenase and lipoxygenase, which are responsible for inflammatory responses.

Phth-dPEG®12-Tris (-TFP Ester)3 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Phth-dPEG®12-Tris (-TFP Ester)3 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

DBCO-dPEG®24-Amido-dPEG®24-DSPE is a building block that can be used in peptide synthesis. It contains a spacer arm with an amine group and a reactive end group, which can be used for attaching to other building blocks or to the amino acid side chain during peptide synthesis. The DBCO-dPEG®24-Amido-dPEG®24-DSPE is also available as part of the Quanta BioDesign Building Blocks kit, which includes seven different building blocks for use in peptide synthesis.

Guangxitoxin-1E is a research tool that belongs to the class of ion channel activators. It can activate ligand-gated ion channels and voltage-gated ion channels, which are important for the transmission of nerve signals. Guangxitoxin-1E can be used as an antibody for immunohistochemistry or Western blotting to detect protein interactions and to study cell biology. It is also useful as a pharmacological tool for studying peptides, proteins, and life science.

Angiotensin II is a peptide hormone that is part of the renin-angiotensin system. It is an antagonist to the angiotensin I receptor, which leads to vasoconstriction, increased blood pressure, and increased water and salt retention by the kidneys. Angiotensin II also stimulates the release of aldosterone from the adrenal cortex, which increases sodium retention by the kidneys and decreases potassium excretion. The peptide is biologically active at nanomolar concentrations.

<p>Amino-dPEG®4-(m-dPEG®24)3 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Amino-dPEG®4-(m-dPEG®24)3 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

Luteinizing hormone-releasing hormone (LHRH) is a protein that is responsible for triggering the release of luteinizing hormone (LH). LH stimulates the production and release of testosterone, which in turn stimulates sperm production. The LHRH gene encodes a protein precursor that is cleaved by proteases to produce mature LHRH. This precursor, called pro-LHRH, can be added to a protein solution to induce follicular growth in rats. Pro-LHRH has been shown to have an effect on the frequency of spermatogenesis. Proteins containing pro-LHRH can be used for hormonal research and as additives for protein solutions.

Amyloid beta-Protein (Human, 1-40) (Scrambled) is a peptide that consists of 40 amino acids. It is a fragment of the amyloid precursor protein. Amyloid beta-protein has been found to have many different effects in the body, including receptor binding, ion channel activation and inhibition, and protein interactions. The peptide is also an activator for the high-affinity nicotinic acetylcholine receptor in the brain. This product can be used as a research tool or as an antibody to study amyloid beta protein in cellular biology.

<p>Azido-PEG3-DYKDDDDK is a peptide containing polyethylene glycol (PEG) as spacer to alter their pharmacokinetic properties and pharmodynamics.</p>

Anti Motilin (Dog) Serum is a fractionated serum that is a potent inhibitor of motilin. It inhibits motilin-induced contractions in the small intestine and colon. The Anti Motilin (Dog) Serum is supplied as a lyophilized powder containing purified fractions of dog serum, which are produced by fractionation on an ion-exchange column. The product contains high purity antibody and peptides with no detectable endotoxin or other microbial contaminants. The Anti Motilin (Dog) Serum is supplied in a volume of 5 mL and has a CAS number of 46887-37-2.

Human Serum Albumin is a stable protein that binds to fatty acids and helps transport them in the circulatory system. It can also bind to other molecules, such as drugs, and help with the transport of these molecules in the bloodstream. The protein is composed of amino acids, which are linked together by peptide bonds. The human serum albumin molecule has four subunits that are connected by disulfide bonds. These subunits are called alpha (α), beta (β), gamma (γ), and delta (δ). Human serum albumin contains many hydrophobic amino acids, which make it soluble in lipids and water. This protein is an important part of energy metabolism because it accepts electrons from fatty acid oxidation and transfers them to electron acceptors such as oxygen or NADPH.

<p>The SARS-CoV-2 spike protein is present on the outside of the virus particles and can bind to angiotensin-converting enzyme II (ACE2) present on the host cells. The C-terminal receptor binding domain (RBD) of the spike protein binds to the N-terminal peptidase M2 domain of ACE2. This receptor binding results in the internalisation of the virus-receptor complex and is, therefore the mechanism of entry of SARS-CoV-2 into host cells.The spike protein residues LITGRLQSL (996-1004) from C have been identified as a T-cell epitope with a predicted HLA restriction. Immune targeting of confirmed epitopes may potentially offer protection against SARS-CoV-2 and help the development of vaccines for long-lasting immunity.</p>

<p>Originally identified in Heloderma horridum horridum (Mexican beaded lizard), exendin-3 is in the glucagon family. Exendin 3 stimulates vasoactive intestinal peptide (VIP) receptors in high concentrations. This leads to increased cAMP levels and amylase secretion in the pancreas. However, low exendin-3 exposure only increases cAMP levels. In applications, exendin-3 was found to induce hypotension by relaxation of cardiac, smooth muscle. Using a tag, exendin-3 is being investigated as a stable agonist for GLP1R to detect insulinomas, a pancreatic B cell-derived cancer with high GLP1R expression. Exendin 3 has also been used on mouse models to assess its effect on glucose-stimulated insulin secretion in glucagon receptor knockout (Gcgr-/-) backgrounds. Understanding the interplay between exendin 3 and metabolism could provide new insights into the obesity crisis.</p>

<p>Custom research peptide; min purity 95%.</p>

m-dPEG®24-DSPE is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®24-DSPE is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Fibroblast growth factor 8 (FGF8) is a cytokine that belongs to the family of fibroblast growth factors. It is a protein that is secreted by cells in the family of organs, including liver, kidney, lung, and heart. FGF8 has been shown to promote cell growth and organogenesis. In addition, FGF8 has been shown to stimulate tumor growth in animal models and humans. The function of FGF8 is mediated through binding to its receptor FGFR-2 on the cell surface. This receptor activates signaling pathways inside the cell by interacting with other proteins such as PI3K or Ras.

<p>Anti GLP-2 (14-33) (Rat) Serum is an antibody that binds to the GLP-2 receptor and blocks its activity. This peptide can be used in research to study the function of the GLP-2 receptor, and is available as a research tool for cell biology, pharmacology, and other life science applications.</p>

MOCA-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH₂ is a peptide that binds to the M1 muscarinic receptor. It is a research tool used in pharmacology and cell biology. This peptide has been shown to activate the M1 receptor, which may be due to its ability to inhibit protein kinase C. This peptide can also be used as an inhibitor of the M1 receptor.

Bradykinin is a peptide that acts as an autacoid, or local hormone. It is a vasodilator, and it stimulates the release of prostaglandins from mast cells in the lungs. Inhibitors of bradykinin include [Thi5,8,D-Phe7]-bradykinin and des-Arg9-bradykinin. Bradykinin has been used as a research tool to study protein interactions, receptor activation, ion channels, and other life science topics.

<p>Acetyl-(Arg)9, derived from (Arg)9 is a cationic cell-penetrating peptide consisting of 9 arginines. Arginine rich CPPs enter cells in a passive manner through membrane multilamellarity and fusion. Evidently as a CPP, (Arg)9 can function to deliver specific molecules to target cells and can be used for drug delivery purposes.</p>

<p>FRET-25Asp is a peptide that can be used in research as an activator, antibody, and inhibitor. It is used as a tool to study protein interactions with the cell membrane and ion channels. FRET-25Asp has also been shown to inhibit the activity of some receptors and ligands.</p>

IL 4 Human, His is a recombinant protein that belongs to the class of peptides. It has been identified as an activator of IL-4 receptor and can be used in research studies to study the interactions between proteins, cells, and receptors. IL 4 Human, His can be used as an antibody to detect IL-4 in cell culture samples. IL 4 Human, His is a high purity product with a CAS Number of 57741-00-8.

<p>t-boc-NH-dPEG®4-Tris (-TFP Ester)3 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. t-boc-NH-dPEG®4-Tris (-TFP Ester)3 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

This product has disulfide bonds between Cys1-Cys15 and Cys3-Cys11, is courced from: Rat, 1-39 and is available as a 0.1mg vial. Big Endothelin-1 (Rat, 1-39) is a precursor peptide of the vasoconstrictor Endothelin-1 (ET-1). ET-1 exhibits vasoconstrictive properties and is an activator of endothelin G-protein coupled receptors. Furthermore ET-1 is produced when inflammation, vascular stress or hypoxia occurs. In vivo Big Endothelin-1 has a greater half life compared to ET-1 and therefore makes it useful to study secretory activity in the endothelial system. Overall Big Endothelin-1 (Rat, 1-39) can be used as a research tool for studying protein interactions, receptor activation and function, and ligand binding. This peptide is also used in pharmacology to study the effects of therapeutic agents on receptor activity and expression.

FRETS-25Met (1 umol) (1umol) is a peptide that binds to the beta2-adrenergic receptor. It is a high purity, research tool and can be used for binding studies as well as for inhibition of the receptor. FRETS-25Met (1 umol) (1umol) has been shown to bind to the beta2-adrenergic receptor with an affinity of 5 nM and an IC50 of 1.6 uM. This peptide has also been shown to act as a potent agonist in stimulating cAMP production in CHO cells expressing the beta2-adrenergic receptor.

FRETS-25Ser is a peptide with a molecular weight of 25.1 Da. It is an activator of the Kv4.3 potassium channel, which has been shown to be involved in memory and learning processes. FRETS-25Ser binds to the extracellular loop 1 of the Kv4.3 channel and modulates its activity by increasing the open probability of the channel and inhibiting fast inactivation. The affinity for this peptide is high, as it binds tightly to its target protein (Kv4.3). FRETS-25Ser also has a low level of inhibition against other channels with similar sequences, as it can only bind to one site on the protein receptor.

Sirtuin-1 is a member of the sirtuin family of proteins, which regulate cell survival and proliferation. Sirtuin-1 regulates gene expression in response to nutrient availability by binding to DNA and modifying histones. It also functions as a homodimer that binds to various regulatory proteins and acts as a repressor or activator of transcription. This protein has been expressed recombinantly in E. Coli, where it may be used as an inhibitor of cancer cell growth. The molecular mass of this recombinant protein is approximately 94 kDa.br>br> Sirtuin-1 is a member of the sirtuin family of proteins, which regulate cell survival and proliferation. Sirtuin-1 regulates gene expression in response to nutrient availability by binding to DNA and modifying histones. It also functions as a homodimer that binds to various regulatory proteins and acts as a repressor or activator of transcription. This protein has been expressed recombinantly in E

Anti Galanin (Porcine) Serum is a research tool that is used to activate, bind, and inhibit the ligand-receptor interactions. It is also used for the study of ion channels and cell biology. Anti Galanin (Porcine) Serum can be used as an antibody or as a peptide in pharmacology studies. The protein interactions are used in life science research, as well as for inhibitor studies.

<p>Urocortin 2 (Mouse)-EIA Kit is a specialty product that can be used to detect the presence of Urocortin 2 in mouse serum. It is an antibody-based sandwich ELISA kit that has been optimized for use in mouse sera and other biological fluids. The kit includes all necessary reagents, including antibodies, standards, and conjugates, to perform an assay. The assay is performed by adding the sample to the plate followed by the detection antibody and a conjugate. After incubation, unbound materials are washed away and the plate is developed with Tetramethylbenzidine (TMB) substrate. A stop solution turns TMB into a blue color that can be measured at 450 nm with a spectrophotometer. The intensity of color corresponds to the concentration of Urocortin 2 in the sample.br&gt;br&gt;<br>The Urocortin 2 (Mouse)-EIA Kit is designed for research purposes only and not for diagnostic</p>

<p>This is a Biologically Active Peptides, Short=PN-II, Proteomics, Amyloid Precursor Protein, New England Peptide calibrated to 25nmol. This peptide has been shown to be a major component of amyloid plaques in Alzheimer's Disease. It is one of the most abundant proteins in the brain and is found in association with beta-amyloid protein (A4). The precursor protein for APP is encoded by the gene on chromosome 21. APP and its products are involved in many cellular processes such as signal transduction, cell proliferation, apoptosis and inflammation. APP can be cleaved by Beta-secretase or Gamma secretase to release A4 and N-APP.</p>

Anti TNF-Alpha (Rat) Monoclonal Antibody is a recombinant rat monoclonal antibody that binds to the TNF-α. It inhibits the effects of TNF-α and has been shown to protect against acute renal failure in rats. Anti TNF-Alpha (Rat) Monoclonal Antibody is a research tool for studying the function of TNF-α, and is used in pharmacological studies as an inhibitor of the enzyme protein kinase C. This antibody can be used for purification of proteins from cell culture or tissue samples.

IL-7 is a cytokine that belongs to the IL-2 family. It is a lymphokine that regulates cell proliferation and differentiation of immune cells, such as T and B cells. IL-7 activates these cells by binding to the IL-7 receptor on their surface. The active form of IL-7 is a homodimeric glycoprotein consisting of two subunits, alpha and beta. The alpha subunit has an N-terminal sequence of amino acids (Lysine - Proline - Glycine) while the beta subunit has a C-terminal sequence (Serine - Asparagine). This protein can be purchased as a research tool, antibody, or purified peptide in high purity from Sigma Aldrich.

TNF-α is a cytokine that is synthesized and secreted by cells such as activated macrophages, T cells, endothelial cells, fibroblasts, and keratinocytes. It has been shown to be a potent mediator of inflammation and plays an important role in the pathogenesis of many diseases. TNF-α is produced in response to immunological stimulation (e.g., LPS) or microbial invasion (e.g., bacteria). It binds to two receptors: TNF receptor 1 (TNFR1) and TNF receptor 2 (TNFR2), which are expressed on many cell types including monocytes, macrophages, neutrophils, dendritic cells, B lymphocytes, eosinophils, mast cells and keratinocytes. The binding of TNF-α to TNFR1 leads to activation of NF-κB and JNK pathways. The binding of TNF-α to TNFR2 leads to activation

<p>Big endothelin-1 (ET-1) is a peptide with a molecular weight of 37.7 kDa that belongs to the class of endothelin peptides. ET-1 is an activator of ion channels and has been implicated in many physiological and pathological processes, including vasoconstriction, angiogenesis, cellular proliferation, and inflammation. The antibody reacts with human ET-1 with a high degree of specificity. It has been used as an immunological reagent for Western blotting and immunoprecipitation experiments.</p>

<p>D-Amino Acid Oxidase is an enzyme that catalyzes the conversion of D-amino acid to alpha keto acid and ammonia. It is also known as DAAO or DAO.</p>

<p>Anti GLP-2 (Rat) Serum is a high purity and potent activator of the GLP-2 receptor. It is a peptide that binds to the GLP-2 receptor and activates it. The GLP-2 receptor is a G protein coupled receptor that belongs to the class of receptors for peptides. Activation of this receptor leads to an increase in intracellular calcium ions and increased cell proliferation, differentiation, and survival. This product can be used as a research tool for Cell Biology, Pharmacology, or Biochemistry studies.</p>

<p>Uroguanylin is a peptide that activates the guanylate cyclase receptor. It is composed of 8 amino acids and has a molecular weight of 1036.5 Da. Uroguanylin is an agonist for the GUCY1A2 receptor, which is responsible for mediating the release of urinary and gastrointestinal hormones such as vasopressin, renin, and gastrin. Uroguanylin binds to one or more other receptors in the kidney or intestine. It can be used as a research tool in cell biology and biochemistry to study ion channels and ligands.br&gt;br&gt;<br>br&gt;br&gt;<br>Uroguanylin is also known by its CAS number 71405-27-8.BR&gt;BR&gt;</p>

<p>Acid-dPEG®9-NHS Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Acid-dPEG®9-NHS Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Anti PACAP (1-15) is a peptide that belongs to the class of activators. It has been shown to activate ion channels, increase intracellular calcium levels, and inhibit ligand-induced receptor desensitization. Anti PACAP (1-15) has also been shown to bind to a number of receptors with high affinity, including the corticotropin-releasing hormone receptor type 2 (CRHR2). This peptide is used as a research tool in cell biology and pharmacology studies.</p>

<p>This peptide is a specific inhibitor of human preprorenin, which is the precursor of renin. The peptide has been shown to inhibit the activation of renin with high specificity and potency.</p>

IL-11 is a cytokine that is synthesized by cells of the immune system and functions as an autocrine growth factor for cells of the myeloid lineage. IL-11's receptor is a protein that binds to the IL-11 peptide and this binding activates intracellular signaling pathways.

EREG Human is a cytokine that belongs to the group of proteins. It is an interleukin-1 receptor antagonist (IL-1Ra) that binds to IL-1 and prevents it from binding with its receptors. EREG Human has been shown to be effective in treatment of inflammatory diseases such as Crohn's disease, rheumatoid arthritis, and ulcerative colitis.

TNF-α is a cytokine that is produced by many cells, including macrophages, T cells, mast cells, and synovial cells. It is a pleiotropic proinflammatory cytokine that has been implicated in cancer and other inflammatory diseases. TNF-α is a potent inducer of cell death through activation of the Fas-FasL death pathway or induction of apoptosis. In addition to its role as an anti-tumor agent, TNF-α has been shown to be important in the regulation of immune responses and inflammation. It also plays an important role in bacterial sepsis by suppressing the production of proinflammatory cytokines such as IL-1β and IL-12 by macrophages.

<p>Elafin is a peptide that is secreted by human neutrophils. It has been shown to inhibit the activity of ion channels and play a role in the regulation of cell proliferation and differentiation. Elafin also interacts with receptors and ligands, which are molecules that bind to other molecules. It is also used as a research tool for studying protein interactions in cell biology. Elafin has been shown to have an anti-inflammatory effect on cells, which may be due to inhibition of the production of prostaglandins.</p>

<p>Carboxyl-dPEG®4-(m-dPEG®8)3 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Carboxyl-dPEG®4-(m-dPEG®8)3 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>monoFITC INSL5 is a peptide that can be used as a research tool to investigate the interactions between proteins and ligands. It is an activator of the Insulin-like growth factor 1 receptor (IGF1R). This peptide has been shown to inhibit IGF1R-mediated signaling pathways that lead to cell proliferation.</p>

<p>The HIV-1 p24 Core Recombinant is a recombinant protein made from the HIV-1 p24 core protein. It has been purified by immunoaffinity chromatography and is specific to the HIV-1 antigen, with minimal cross-reactivity to other viruses. The HIV-1 p24 Core Recombinant is found in the form of a chain of polypeptides, which are chains of amino acids that form proteins. This protein can be used as an immunoreactive reagent for detecting antibodies against HIV-1 in human serum or plasma.</p>

<p>MAL-dPEG®4-NHS Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. MAL-dPEG®4-NHS Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>A synthetic cone snail toxin sourced form the marine snail, conus striatus. This product has disulfide bonds between Cys1-Cys16,Cys8-Cys20, and Cys15-Cys26 and is available as a 0.5mg vial.</p>

<p>Maleimide-activated BSA (BSA-M) is a maleimide-activated form of Bovine Serum Albumin (BSA). It is a peptide that can be used for immunization, as well as in biochemistry experiments. BSA-M has been shown to stimulate antibody production and can be used in the development of new vaccines.</p>

<p>H-Trp-2-ClTrt-Resin is a resin that has been used for the synthesis of peptides. It can be used as a building block for peptides, or as a building block in the synthesis of other compounds. H-Trp-2-ClTrt-Resin is available in two mesh sizes: 200 mesh and 400 mesh. The resin is soluble in ethyl acetate and alcohols, but insoluble in water.</p>

<p>Myelin Oligodendrocyte Glycoprotein (MOG) is a glycoprotein that is expressed by oligodendrocytes and is essential for the myelinization of axons in the central nervous system. MOG has been associated with the development of multiple sclerosis and demyelinating diseases. Freeze-dried MOG is reconstituted with water before use, which may be beneficial for patients who cannot swallow pills or capsules. The reconstituted protein can be injected intravenously as an allograft. Myelin Oligodendrocyte Glycoprotein can also be used long-term after desiccating to prevent its degradation and loss of biological activity. The expansion of the chromosome carrying the gene for MOG has been shown to be associated with multiple sclerosis and other neurologic diseases.</p>

<p>Big Gastrin, is a hormone which exerts its effects through activating the G-protein coupled receptor CCK2R and plays a role in gastric acid secretion. Big Gastrin can be used in research applications such as pharmacology and cell biology. This product is also a potential growth factor in some cancer tumors, including prostate cancer. It is available as an ammonium salt and as a 0.1mg vial.</p>

<p>Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp is a peptide that is an elastase substrate derived from PAI-1</p>

<p>Dns-Glu(Cys-Gly) is a peptide that is reactive and can be used as a biochemical. It has been shown to have both reactive metabolites and biologically active peptides.</p>

<p>The ELISA (enzyme-linked immunosorbent assay) is a powerful and sensitive technique to detect and quantify antigens of interest in biological samples. The Insulin ELISA kit from Specialty Products and Technologies contains the reagents necessary for in vitro measurement of human insulin in serum, plasma, or urine. This kit utilizes a monoclonal antibody specific for human insulin as the detection antibody. The Insulin ELISA Kit is designed to measure human insulin concentrations in range 0.5-25 ng/mL with an accuracy of ±15%.</p>

<p>Matrix Metalloproteinase-1 is a recombinant human protein that is used as a research tool to study the function of matrix metalloproteinases. It has been shown to bind to peptides and activate them, which may lead to new insights into their function. Matrix Metalloproteinase-1 also binds to ion channels and ligands, which may be useful for understanding the role of these molecules in diseases such as cancer.</p>

<p>The leptin (RAT)-HS ELISA Kit is a sandwich enzyme-linked immunosorbent assay kit for the quantitative measurement of rat leptin in serum or plasma. Rat leptin is a protein hormone that regulates body weight, food intake, and energy expenditure. Leptin is synthesized and secreted by adipose tissue in proportion to fat mass. The human form of this hormone is called human leptin.</p>

Lipid A is a bacterial endotoxin that activates macrophages and dendritic cells, which in turn activate T-cells. It is a ligand for the CD14 receptor, which is a pattern recognition molecule found on macrophages and dendritic cells. Lipid A also binds to the Toll-like receptor 4 (TLR4) on host cells, initiating an inflammatory response. Lipid A has been used as a research tool to study cell biology related to activation of macrophages and dendritic cells leading to cytokine production. This activator has also been used as a ligand in antibody studies, ion channel studies, protein interactions, pharmacology experiments with peptides, and life science research.

<p>CTGF Human is a research tool that is used to investigate how CTGF interacts with its receptor and other proteins. The CTGF protein can bind to the Cell Biology, Antibodies, Ion Channels, Pharmacology, Peptides, and Life Science fields. It is an inhibitor for Lipases.</p>

<p>Anti PACAP38, humanSerum is a research tool that can be used to study the role of PACAP in various biological processes. The antibody is generated against human PACAP38 and has been shown to inhibit the activity of this peptide. The antibody also binds to the receptor for this peptide, which is a G protein-coupled receptor. This antibody can be used as an inhibitor of PACAP and its receptor in various cell types.</p>

<p>TentaGel Macrobead PHB Resin is a polymer resin which is used for the synthesis of peptides. The resin can be used as a building block in peptide synthesis, as well as being mixed with other resins for use in other applications. TentaGel Macrobead PHB Resin is supplied in particles that are made up of polystyrene beads and hydroxypropyl-b-cyclodextrin (PHB) groups. The PHB groups are designed to bind to peptides during the synthesis process, while the polystyrene bead provide a support matrix. This product is primarily used by researchers who are interested in using it for the study of protein structure and function.</p>

<p>m-dPEG®12-Propionaldehyde is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®12-Propionaldehyde is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Anti Galanin (9-30), humanSerum is a peptide that inhibits the activity of galanin, which is a neuropeptide. It has been shown to have an effect on ion channels and receptors in the central nervous system. Anti Galanin (9-30), humanSerum binds to the receptor for galanin and blocks the binding of galanin molecules to these receptors, preventing activation of these cells. Anti Galanin (9-30), humanSerum is used as a research tool for studying protein interactions and as a pharmacological inhibitor for studying ion channels and receptors in the central nervous system.</p>

<p>Anti Na Channel ll (467-485) (Rat) Serum is an anti-Na channel antibody that can be used for research purposes. It is a monoclonal antibody that has been generated according to the sequence and features of the rat N-type voltage-gated sodium channels. The affinity of this antibody for its target is high, with a Kd of 0.5 nM. This antibody can be used in immunoassays, Western blots and immunoprecipitations to determine the level of Na channel expression in various tissues.</p>

Ferredoxin-1 is a peptide that belongs to the group of activators. It can be used as an inhibitor, or as a receptor or ligand in pharmacological experiments. Ferredoxin-1 has been shown to inhibit ion channels and protein interactions. This protein may also have implications for cell biology and is used as a research tool for life science. The CAS number for ferredoxin-1 is 107899-38-2.

<p>Pancreastatin is a peptide that is an inhibitor of potassium channels. Pancreastatin binds to and blocks the opening of K+ channels, thereby inhibiting the propagation of action potentials. Pancreastatin is a potent inhibitor of voltage-gated K+ channels in pancreatic β-cells and inhibits insulin secretion. Pancreastatin has been shown to inhibit the activity of sodium channels in the central nervous system, which may have therapeutic benefits for patients with epilepsy or other seizure disorders. Pancreastatin also has inhibitory effects on norepinephrine release from sympathetic nerves and acetylcholine release from parasympathetic nerves, which may be beneficial for patients with Parkinson's disease or Alzheimer's disease.</p>

<p>CD2, human, recombinant is a research peptide that is commonly used in scientific studies. It is a protein that is produced using Escherichia Coli bacteria. CD2 plays an important role in immune responses and cell signaling. This recombinant form of CD2 allows researchers to study its function and interactions with other molecules in a controlled laboratory setting. It can be used in various experiments and assays to investigate the mechanisms of immune system regulation and develop potential therapeutic interventions. With its high purity and quality, CD2, human, recombinant is a valuable tool for researchers in the field of immunology and molecular biology.</p>

<p>MAL-dPEG®2-NHS Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. MAL-dPEG®2-NHS Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

Thymosin β4 is a polypeptide hormone that has been studied in a variety of medical conditions. It was first discovered in the thymus gland, but is also found in other tissues, including the intestine and heart. Thymosin β4 is involved in the process of wound healing, regulating the production of collagen and fibrinogen. It also has cardioprotective effects by preventing myocyte apoptosis. There have been studies that show that thymosin β4 may be useful for treating chronic kidney disease, colorectal cancer, and polyps. The effects of this protein are mediated by its ability to regulate cellular proliferation and differentiation.

<p>TentaGel; is a gelatinous resin, an important support for solid phase synthesis. TentaGel resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol) as shown below. The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix.</p>

Anti C-Peptide II (Rat) Serum is a high-purity peptide that can be used as a research tool to study the pharmacology of peptides and their interactions with receptors. It can also be used as an inhibitor in cell biology experiments.

<p>The amyloid β-protein (Aβ) is a peptide of 40 amino acids that is a major constituent of the amyloid deposits in the brain. The Aβ peptide is derived from the proteolytic cleavage of the beta-amyloid precursor protein (APP). This product can be used as a research tool and as an activator or ligand for receptor, cell biology, antibody, ion channels, and pharmacology. It can also be used to study protein interactions and peptides in life science.</p>

Hemoglobin, α 2, human, recombinant is a protein that belongs to the group of hemoglobins. It is a recombinant protein that has been produced by inserting the human alpha-2 globin gene into a bacterial expression system. This product can be used as an ion channel probe, an activator of G-protein coupled receptors or as an inhibitor of ligand binding to receptors. It has been shown to interact with a variety of peptides and proteins. Hemoglobin, α 2, human, recombinant can be used in research for cell biology and pharmacology studies.

<p>Anti Preprogalanin (89-124) (Rat) Serum is a research tool that can be used to study the interactions of proteins with other proteins, peptides, and receptors. Anti Preprogalanin (89-124) (Rat) Serum has been shown to activate ion channels and ligand-gated ion channels. It also has an antibody against it, which can be used in immunoassays. This serum is purified from rat plasma and contains no preservatives.</p>

<p>BD 3 MOUSE is a peptide that is used as a research tool for the study of ion channels. BD 3 MOUSE is an activator of the nicotinic acetylcholine receptor. It can be used to inhibit protein interactions, such as those between ligands and receptors. BD 3 MOUSE is also an inhibitor of potassium channels, which are important for neuronal excitability and muscle contraction. This peptide has been shown to bind to voltage-gated sodium channels, leading to a decrease in sodium current. This inhibition leads to an increase in action potential duration and amplitude.</p>

<p>t-boc-N-Amido-dPEG®23-Amine is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. t-boc-N-Amido-dPEG®23-Amine is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Beta-ANP is a peptide that belongs to the class of activators. It is an inhibitor of ion channels and has been shown to be a ligand for the beta-1 adrenergic receptor. Beta-ANP has been used as a research tool in cell biology, pharmacology, and biochemistry.</p>

<p>NRG1 B1 Human is a cytokine that is produced by human cells. It belongs to the group of interleukins and functions as an inflammatory mediator. NRG1 B1 Human is involved in a wide range of biological processes, such as the regulation of cellular proliferation, differentiation, and immune response. It may also be used as a treatment for cancer.</p>

<p>Bis-MAL-Lysine-dPEG®4-dPEG®12-Tris(m-dPEG®24)3 is a peptide containing polyethylene glycol (PEG) as spacer to alter their pharmacokinetic properties and pharmodynamics.</p>

<p>Please enquire for more information about Z-Asn-Gly-OH trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>PC Biotin Alkyne probes eliminate a major limitation of the streptavidin-biotin affinity purification. This reagent contains a biotin moiety linked to an azide moiety through a spacer arm containing a photocleavable linker. Captured biomolecules can be efficiently released under mild, reagent-free conditions (irradiation with near-UV, low intensity lamp) and the small molecular fragment (55.07 Da) left on the labelled protein following cleavage. These features make the photocleavable probe especially attractive for use in biomolecular labelling and proteomic studies.</p>

<p>Human GH (1-43) ELISA Kit (1ea) is a sandwich enzyme-linked immunosorbent assay for the quantitative measurement of human GH in serum. It has demonstrated cross-reactivity with monkey, rat, and mouse GH, but not bovine or porcine GH.</p>

<p>Ac-Asp-Gln-Thr-Asp-H aldehyde is a peptide that can act as an activator, inhibitor, or ligand for ion channels and receptors. It has been shown to be a high purity reagent in the field of cell biology and pharmacology.</p>

<p>Peptide H-WLGFIAGLIAIVMVT-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Tyrosinase protein:<br>Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV) is a human tyrosinase-derived (369-377) peptide by posttranslational conversion of the sequence YMNGTMSQV. Tyrosinase is an oxidase membrane-bound protein. Tyrosinase play a key role in the melanin synthesis pathway. Tyrosinase is presented on the surface of HLA-A*02:01 melanomas and also expressed in melanocytes. Tyrosinase has been still suggested to be a tumor antigen and might be implicated in improvement of immunotherapeutic strategies such as for efficient anticancer vaccine development.<br>Applications of Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV):<br>Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV) is used to stimulate specific cytotoxic T lymphocytes (CTL) in PBMCs and then to analyze CTL response especially the cytokine production by ELISPOT assay. Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV) is also involved in experimental therapies of metastatic melanoma by allogeneic hematopoietic stem cell transplantation. In fact, cytotoxic T cells were generated from peripherical blood mononuclear cells (PBMCs) of HLA-A*02:01 healthy donors after being stimulated by injection of Asp371 antigen (2). This strategy raises issues which concern the graft versus tumor (GvT) effect and graft versus host disease (GvHD).</p>

<p>H-Thr-Glu-OH is a nucleotide that is a component of RNA. It is one of the 20 natural amino acids and it is found in proteins as well as in RNA molecules. H-Thr-Glu-OH can be synthesized by hydrolysis of proteins with an enzyme called glutamic acid hydrolase. H-Thr-Glu-OH has been shown to have a high affinity for lysine, which has been shown to be required for the enzymatic activity of many protein enzymes. This amino acid can also be found in large quantities in cheese, soy sauce, and yogurt.</p>

IL-17 Rat is a recombinant protein that is used as an immunological research tool. It is also used as a ligand to study the IL-17 receptor. IL-17 is a cytokine that activates cells in the immune system, such as T cells, B cells, and natural killer cells. This protein can be used in cell biology experiments to study cytokine signaling pathways and has been shown to inhibit ion channels. IL 17 rat can also be used in pharmacology studies to assess its effects on peptides and proteins within the body.

<p>This product is produced via the activation of mariculture Keyhole Limpet (Megathura crenulata) Hemocyanin with a maleimide group.  The activated material will readily bind free sulfhydryl groups present in solution.KLH is a highly antigenic protein with a high molecular mass (4.5 x 105 - 1.3 x 107 Daltons, in aggregates of 350 and 390 kDa subunits) that elicits a strong immune response when used to immunize animals.As many as 400 moles of Cysteine-containing peptide can bind to one mole of maleimide-activated KLH.</p>

<p>Boc-Arg(Boc)2-OH is a protected derivative of the amino acid arginine. The Boc (tert-butyloxycarbonyl) groups shield both the amino group and the side chain's guanidine functionality. This protection scheme allows for its selective incorporation during peptide synthesis while offering stability under various reaction conditions. Boc-Arg(Boc)2-OH has been also used in the synthesis of amino acid prodrugs of cytotoxic anthraquinones, demonstrating its potential utility in developing targeted cancer therapies.</p>

Rabbit serum against growth hormone-releasing factor (GRF) or GHRH (growth hormone-releasing hormone).

Amino-dPEG®12-t-boc-Hydrazide is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Amino-dPEG®12-t-boc-Hydrazide is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

<p>Please enquire for more information about H-Asp-Val-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Asp-Leu-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>This is a vivitide catalogue product. Please send your vivitide product enquiry to sales@vivitide.com for an up-to-date price and availability.</p>

The Anti NO Synthase II (77-105) (Rat) Serum is a research tool that can be used to activate, ligand or receptor. It can also be used to study cell biology as well as protein interactions. The Anti NO Synthase II (77-105) (Rat) Serum can inhibit ion channels and is a high purity antibody. This serum is made of peptides and proteins.

NHS-m-dPEG® (MW = 685) is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. NHS-m-dPEG® (MW = 685) is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

<p>IL-22 is a cytokine that regulates the immune system and has been shown to play a role in the development of Th1 cells. IL-22 is an activator for IL-22 receptor and can be used as a ligand or antibody for research purposes. IL-22 is not known to interact with ion channels, but it does bind to cell membranes. IL-22 is also used as a pharmacological tool for studying protein interactions, such as peptides, and is also useful in cell biology research.</p>

<p>Please enquire for more information about Thyroid Stimulating Hormone Human including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Lys(1-Deoxyfructosyl) is a research tool used in cell biology and pharmacology. It interacts with many receptor types, such as ion channels, ligands, and antibodies. Lys(1-Deoxyfructosyl) binds to receptors and activates them. This leads to changes in the cells that are observed under a microscope. Lys(1-Deoxyfructosyl) has also been shown to inhibit protein interactions in living cells.</p>

<p>3x DYKDDDDK peptide, also called 3x FLAG peptide, is a 23 aa length peptide used for the competitive elution of DYKDDDDK-tag fusion proteins (with excess of free 3x DYKDDDDK peptide) under non-denaturing conditions, especially when a DYKDDDDK-tagged protein is sensitive to low pH.</p>

<p>EPGN Human is a research tool that is an activator, ligand, and receptor. It is also used in Cell Biology as an antibody and an ion channel. EPGN Human is used in pharmacology as a peptide. EPGN Human has high purity and can be used in Life Science for protein interactions or as an inhibitor.</p>

Kallidin is a peptide that has regulatory effects on tissue remodeling, inflammatory responses, and the growth of new blood vessels. It is found in a number of tissues, including extracellular matrix proteins, where it acts as a regulator. Kallidin has been shown to regulate kinins, which are hormones that are responsible for the regulation of inflammation. Kallidin also regulates collagen and fibrinogen production by stabilizing these proteins. This peptide also induces leukocyte recruitment and polymorphonuclear leukocytes (PMN) activity. Kallidin can stimulate growth factor production and may play an important role in the stabilization of matrix proteins such as fibronectin.

<p>Amylin (Rat) Antiserum is a protein that is used as an inhibitor in research. It is also a ligand for the insulin receptor and can be used to study its activity. Amylin (Rat) Antiserum binds to the extracellular domain of the receptor and blocks it from binding to insulin. This prevents the activation of downstream signalling pathways, which are responsible for glucose uptake and metabolism. Amylin (Rat) Antiserum can be used as a research tool to study ion channels due to its ability to block potassium channels. The antibody has been shown to bind with high purity with little cross-reactivity in immunoassays, making it ideal for use in laboratories.</p>

As a member of the tachykinin neuropeptide family, Neurokinin B is involved in the dilation of blood vessels, the contraction of smooth muscles and the excitation of neurons. This product can be applied as a NK3 receptors selective agonist.

Human pleiotrophin is a peptide that belongs to the family of neuropeptides. It has been shown to bind to ion channels in the cell membrane and is believed to regulate their function. This protein also binds with high affinity to the receptor tyrosine kinase, which are important for many cellular functions including signal transduction and cell growth. Pleiotrophin has been used as a research tool for studying protein interactions and for understanding how ion channels work. It can be used to study the mechanisms of various diseases such as hypertension, asthma, and diabetes mellitus.

<p>Please enquire for more information about IgA1 Hinge Region Peptide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Huwentoxin IV is a potent analgesic that has been shown to have antinociceptive properties in animals. Huwentoxin IV blocks the voltage-gated sodium channel NaV1.8 and prevents the transmission of pain signals to the brain. This drug has also been shown to inhibit the activity of voltage-gated potassium channels KV1.3 and KV1.5, which are involved in neuronal excitability, suggesting that huwentoxin IV may have other therapeutic applications. Huwentoxin IV interacts with disulfide bonds and is an effective inhibitor of voltage-gated sodium channels, but not voltage-gated potassium channels, at low concentrations (10 μM).</p>

<p>Jingzhaotoxin III is a small peptide that has been expressed in Drosophila melanogaster and has been shown to have an inhibitory effect on brain natriuretic peptide (BNP). Jingzhaotoxin III decreases the amplitude of BNP-induced camp levels, and this decrease can be reversed by removing extracellular calcium. Jingzhaotoxin III also has a voltage-gated sodium channel blocking effect, which can be inhibited by adding extracellular calcium. Jingzhaotoxin III interacts with calyces and blocks their activation. This inhibition of calyx activation is reversible when extracellular calcium is removed.</p>

GPCD peptide; synthetic substrate that mimics the DPP-IV (dipeptidyl peptidase IV) natural substrate. 95%, TFA salt.

Please enquire for more information about L-Cysteinyl-L-lysine trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

8-Oxoguanine DNA glycosylase is a glycosylase enzyme that repairs the 8-oxoG DNA base. It has been purified from human and Escherichia coli cells and recombinantly produced in E. coli. The enzyme has a molecular mass of about 42 kDa and is composed of two polypeptide chains with an apparent molecular weight of 17 kDa each. 8-Oxoguanine DNA glycosylase has been shown to have a broad substrate range, including both oxidized and reduced forms of 8-oxoG, as well as other oxidized purine bases such as 7,8-dihydrothymine (8-hydroxyguanine) and 5,6-dihydrothymine (5,6-dihydroxyguanine). The enzyme catalyzes the removal of the damaged base from the DNA backbone without any concomitant chemical changes in the sugar or phosphate groups

<p>An Apolipoprotein B light tryptic peptide standard for use in protein identification and quantitation studies. Apolipoprotein B is responsibly for carrying lipids such as low density lipoprotein (LDL), chylomicrons, intermediate-density lipoprotein, very low-density lipoprotein and lipoprotein (a).</p>

Ac-Gly-Ala-Lys(Ac)-AMC is a fluorescent compound that reacts to the presence of amino acids. It is used as a research chemical, speciality chemical, and versatile building block. Ac-Gly-Ala-Lys(Ac)-AMC has been shown to be useful in the synthesis of complex compounds and fine chemicals.

Please enquire for more information about Alloferon 1 trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Hydroxyacyl-Coenzyme A Dehydrogenase is an enzyme that catalyzes the oxidation of hydroxyacyl-CoA to form acetyl-CoA. It is a member of the short-chain dehydrogenases/reductases (SDR) superfamily. Hydroxyacyl-Coenzyme A Dehydrogenase is expressed in many tissues and has been shown to be essential for fatty acid synthesis and catabolism, as well as for the conversion of ketone bodies to acetyl-CoA. It also plays a role in cellular respiration and energy production.

<p>Peptide H-VLIQFLQK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>α 1 Antitrypsin Human is a research tool that can be used in the study of protein interactions. It is a high-purity, recombinant, human α 1 antitrypsin with an N-terminal hexahistidine tag. It has been specifically designed for use in antibody production and as a pharmacological agent to inhibit trypsin-like enzymes.</p>

<p>Conantokin G trifluoroacetic acid is a peptide that is derived from the conantokins. It has been shown to have neuroprotective properties and inhibitory properties. Conantokin G trifluoroacetic acid binds to calcium in neuronal cells, which leads to the inhibition of glutamate-induced neuronal death and brain infarction. The binding of this peptide to calcium also inhibits intracellular signalling pathways, leading to an anti-inflammatory response. In addition, this compound may be a potential therapeutic agent for chronic oral toxicity due to its ability to bind with glutamate receptors and prevent activation.</p>

Please enquire for more information about Pirin Human Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page

For Protein Identification and Quantitation

Myr-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu is a peptide that has been shown to activate potassium channels in the central nervous system. It has been suggested as a potential treatment for epilepsy and Parkinson's disease. Myr Ser Ile Tyr Arg Arg Gly Ala Arg Arg Trp Arg Lys Leu is also an inhibitor of ligand binding to the GABA receptor, which may be useful in the treatment of anxiety disorders.

<p>MAL-dPEG®4-Glu(TFP Ester)-NH-dPEG®4-Glu(TFP Ester)-NH-m-dPEG®24 is a peptide containing polyethylene glycol (PEG) as spacer to alter their pharmacokinetic properties and pharmodynamics.</p>

For Protein Identification and Quantitation