Peptides

Boc-Leu-Thr-Arg-AMC is a fluorescent ligand used in research as a tool to study ion channels. It is a peptide that activates the receptor, which can be used to inhibit the channel and its function. This compound has high purity and is an inhibitor of ion channels.

<p>m-dPEG®24-Propionaldehyde is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®24-Propionaldehyde is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Bone morphogenetic protein-2 is a secreted signaling protein that belongs to the transforming growth factor beta (TGF-β) superfamily. It has been shown to stimulate bone formation, inhibit bone resorption and stimulate cartilage production. BMP 2 is an activator of receptors for type I and II receptors for TGF-β. This peptide has also been shown to activate ion channels and inhibit ligands of receptor tyrosine kinases. BMP 2 binds to cell surface receptors and can be used as a research tool in the study of cell biology, pharmacology, and receptor function.</p>

Fmoc-N-Amido-dPEG®8-TFP Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Fmoc-N-Amido-dPEG®8-TFP Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Alpha-1-Acid Glycoprotein light tryptic peptide standard for protein identification and quantitation. Alpha-1-Acid Glycoprotein is an acute phase protein whose concentration in serum increases during, infection, inflammation and tissue injury.

<p>Insl3 is a protein that is localized in the ovary and human chorionic gonadotropin. It is also found in human serum. In animals, Insl3 causes fertility. In humans, it stimulates the development of the gubernaculum, which attaches to the testes. The expression of Insl3 increases during puberty and continues to be expressed throughout adulthood. Insl3 is translated from mRNA as a precursor protein with an N-terminal signal peptide sequence that directs its secretion from the cell into the extracellular space. The Insl3 precursor protein has two C-terminal domains: an internal domain and a carboxy-terminal domain. These domains are translated from separate initiation codons on one mRNA molecule. The internal domain contains sequences for translation initiation, ribosome binding sites, and translational stop codons; these sequences are not present in the carboxy-terminal domain. Insl3 can be detected by using an</p>

<p>FRETS-25Tyr (1 umol) (1umol) is a peptide that is used as a research tool for the study of protein interactions, receptor function, ion channels and ligand binding. FRETS-25Tyr (1 umol) (1umol) is an activator of protein kinase C and has been shown to inhibit ion channels. This peptide is also used in the study of cell biology, with an antibody that detects it. FRETS-25Tyr (1 umol) (1umol) has high purity and CAS No. 6058-57-2.</p>

<p>Bromoacetamido-dPEG®24-Amido-DBCO is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Bromoacetamido-dPEG®24-Amido-DBCO is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>β-Defensin-2 is a protein that belongs to the class of defensins. It has been shown to have antimicrobial activity against a wide range of microorganisms and to be an activator of ion channels. β-Defensin-2 is also a ligand for the GPR18 receptor, which may be involved in the regulation of pain perception. β-Defensin-2 is purified from human leukocytes and has a purity of &gt;98%.</p>

<p>NPY is a peptide that is released by neurons and acts as an activator. It is also found in the central nervous system and regulates appetite, as well as other autonomic, behavioral, and endocrine functions. NPY has been shown to be an inhibitor of ion channels in the central nervous system. NPY has been shown to bind to receptors on the surface of cells, which are ligands for NPY. This binding activates or inhibits the receptor's signaling pathway. The CAS number for NPY is 1139-14-1 and it has a molecular weight of 9.6 kDa.END&gt;</p>

[D-Ala2,Met5]-Enkephalinamide is a peptide that belongs to the group of opioid peptides. It acts as an agonist and binds to the µ-opioid receptor. This receptor is involved in transmitting signals from outside the cell to inside the cell by regulating ion channels and controlling protein interactions. The binding of [D-Ala2,Met5]-Enkephalinamide to this receptor results in an inhibitory effect on neurotransmitter release, leading to a decrease of pain sensation. It has also been shown that [D-Ala2,Met5]-Enkephalinamide can act as an antagonist at other opioid receptors, such as the κ-opioid receptor.

Orexin-A is a peptide that has been shown to activate orexin receptors, which are ligand-gated ion channels. It is used as a research tool in cell biology and pharmacology. Orexin-A, also known as hypocretin-1, is an endogenous neuropeptide that regulates arousal and wakefulness. The activation of the orexin receptor by Orexin-A leads to the opening of voltage-gated Ca2+ channels, resulting in Ca2+ influx into the cell and increased neurotransmitter release. Orexin-A binds to both orexin receptor subtypes (orexins 1 and 2) with similar affinity but with different binding modes. This antibody can be used for western blotting or immunohistochemistry studies in order to detect the presence of Orexin-A in cells or tissues.

<p>Cytochrome P450 3A4 is an enzyme that is involved in the metabolism of a wide range of compounds, including drugs and other xenobiotics. CYP3A4 can metabolize a drug from one chemical to another by adding or removing a functional group. CYP3A4 also has monooxygenase activity, meaning it can convert one compound into another using oxygen as a reactant. CYP3A4 is responsible for the metabolism of many drugs and is commonly found in humans, mice, rats, dogs and cattle.</p>

<p>Mu-conotoxin GIIIB is a peptide that acts as an inhibitor of the nicotinic acetylcholine receptor. This toxin blocks the activation of the receptor, which leads to paralysis and death. Mu-conotoxin GIIIB is a highly purified peptide that has been shown to be a useful research tool for studying ion channels and their interactions with other proteins. The protein has also been used as an effective drug in treating myasthenia gravis and neuromuscular disorders.</p>

Monobiotin INSL5 is a peptide that is biologically active and is obtained from the New England Peptide Company. Monobiotin INSL5 has shown to be an antagonist of the insulin-like growth factor II receptor and may have potential as a therapeutic agent for diabetes mellitus.

Apolipoprotein A1 heavy tryptic peptide standard for protein identification and quantitation studies. Apolipoprotein A1 is a structural component of high density lipoprotein (HDL) and is involved in cellular cholesterol homeostasis and reverse cholesterol transport.

<p>β-Defensin-1 is a member of the α-defensin family of antimicrobial peptides. It has been shown to be an activator of the LPS receptor and is involved in the regulation of ion channels in cells. β-Defensin-1 is a ligand for the GPR37 receptor and inhibits protein synthesis, which may be due to its ability to bind to other proteins, such as chemokines. β-Defensin-1 also has antibacterial activity against some strains of bacteria, including Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus. <br>β-Defensin-1 is a high purity recombinant human protein that can be used as an inhibitor for pharmacological studies.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of GPT antibody, catalog no. 70R-1215</p>

RS09/Toll Like Receptor (TLR) 4 agonist – APPHALS

<p>Native Melan-A (26-35) decapeptide derives from the melanocyte lineage-specific protein Melan-A/MART-1, which is expressed in almost 75-100% of primary and metastatic melanomas.<br>The region 26-35 of Melan-A protein acts as an antigenic peptide that is recognized by CD8+ tumor-reactive cytolytic T lymphocytes (CTLs) for designing antigen-specific cancer vaccines1. It has been shown that CD8+ Melan-A-specific CTLs isolated from melanoma patients efficiently lyse the Melan-A-expressing HLA-A*0201+ melanoma cell line. However, CTLs preferentially recognize the Melan-A (26-35) peptide as compared with the Melan-A (27-35) peptide. Moreover, the Melan-A (26-35) A27L analog (ELAGIGILTV) has a higher binding affinity to HLA-A*0201 than the native Melan-A (26-35) peptide (EAAGIGILTV), and consequently displays more potent antigenicity and immunogenicity.<br>It has been reported that the concentration of Melan-A (26-35) A27L analog required to obtain 50% of maximal antigenic activity (EC50) is 0.01nM, whereas that of the native Melan-A (26-35) peptide is 0.25nM1. Therefore, the relative activity of Melan-A (26-35) A27L analog is 25 fold higher than that of the native Melan-A (26-35) peptide.<br>Furthermore, functional competition assay has shown that the concentration of Melan-A (26-35) A27L analog required to achieve 50% inhibition (IC50) of tumor lysis is 2nM, which is 10 fold lower than that of the native Melan-A (26-35) peptide. Regarding peptide stability in human serum, the half-lifes (t1/2) of the native Melan-A (26-35) peptide and the A27L analog are quite similar (45 and 40min, respectively) as measured by HPLC-ESI-MS, but much higher than that of the Melan-A (27-35) nonapeptide (5min).</p>

Human GIP (Active) ELISA (1ea) is a human GIP ELISA kit that detects the presence of active human GIP in a sample. This kit is designed to detect human GIP in serum, plasma, and urine. The assay has been validated for the quantitative measurement of active human GIP in samples from healthy subjects and patients with type 2 diabetes mellitus.

<p>TentaGel® R PHB Resin (90 um) can be used for the preparation of peptide acids; particle size 90 µm; capacity: 018-023 meq/g and is specially designed for difficult and long sequences.<br>TentaGel, is a gelatinous resin, an important support for solid phase synthesis. TentaGel resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol) as shown below. The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix.</p>

<p>Neuromedin U is a neuropeptide that has been found to bind to the receptor neuromedin U receptor. It is a potent activator of ion channels and ligand for the neuromedin U receptor. Neuromedin U is also an inhibitor of angiotensin II, histamine, and serotonin release. The purified recombinant human neuromedin U protein is supplied at &gt;98% purity with no detectable endotoxin contamination.</p>

<p>Gp100 (25-33), human is a fragment of the human melanoma antigen. It is a 9-amino acid (AA) epitope restricted by H-2Db and recognized by the T cells. Gp100 (25-33) induces CD8+ T cells capable of recognizing B16 melanoma specifically.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>FRETS-25Asn (1 umol) (1umol) is a peptide that is an activator of the FRET sensor. FRETS-25Asn (1 umol) (1umol) binds to the receptor, which activates the FRET sensor and produces a fluorescent signal. This peptide can be used for research purposes, such as studying protein interactions or measuring ion channels in cells.</p>

<p>Portion of EBV EBNA 4NP</p>

<p>(Arg)9 is an cell-penetrating peptide made up of 9 arginine residues capable of traversing plasma membranes. It has been shown that Arg9 destabilize and disrupt the phospholipid bilayer allowing flow of ions across the membrane. (Arg)9 peptide plays an important role in efficient cellular uptake. The guanidinium group is a critical structural determinant for tight and rapid interactions with cell membrane. The cationic guanidinium group can form electrostatic interactions with anionic cell membranes components such as phospholipids and sulphated proteoglycans. This interaction can trigger the activation of specific intracellular signalling and cell internalization via various pathways. (Arg)9 peptide is used to deliver a variety of functionally active cargos such as peptides, small interfering RNA, oligonucleotides, plasmid DNA and liposomes into mammalian cells and plant cells with high translocation efficiency. (Arg)9 peptide can also be used to form chemical linkages with the cargo and act as a carrier peptide.</p>

<p>Peptide H-DRV^YIHPFHL-OH is a heavy labelled form of Angiotensin I peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Portion of HCMV</p>

<p>Analog of the native Melan-A (26-35) decapeptide derives from the melanocyte lineage-specific protein Melan-A/MART-1, which is expressed in almost 75-100% of primary and metastatic melanomas.<br>The region 26-35 of Melan-A protein acts as an antigenic peptide that is recognized by CD8+ tumor-reactive cytolytic T lymphocytes (CTLs) for designing antigen-specific cancer vaccines1. It has been shown that CD8+ Melan-A-specific CTLs isolated from melanoma patients efficiently lyse the Melan-A-expressing HLA-A*0201+ melanoma cell line. However, CTLs preferentially recognize the Melan-A (26-35) peptide as compared with the Melan-A (27-35) peptide. Moreover, the Melan-A (26-35) A27L analog (ELAGIGILTV) has a higher binding affinity to HLA-A*0201 than the native Melan-A (26-35) peptide (EAAGIGILTV), and consequently displays more potent antigenicity and immunogenicity.<br>It has been reported that the concentration of Melan-A (26-35) A27L analog required to obtain 50% of maximal antigenic activity (EC50) is 0.01nM, whereas that of the native Melan-A (26-35) peptide is 0.25nM1. Therefore, the relative activity of Melan-A (26-35) A27L analog is 25 fold higher than that of the native Melan-A (26-35) peptide.<br>Furthermore, functional competition assay has shown that the concentration of Melan-A (26-35) A27L analog required to achieve 50% inhibition (IC50) of tumor lysis is 2nM, which is 10 fold lower than that of the native Melan-A (26-35) peptide. Regarding peptide stability in human serum, the half-lifes (t1/2) of the native Melan-A (26-35) peptide and the A27L analog are quite similar (45 and 40min, respectively) as measured by HPLC-ESI-MS, but much higher than that of the Melan-A (27-35) nonapeptide (5min).</p>

<p>Portion of Influenza A</p>

<p>MOG(91-108) corresponds to amino acids 97 to 108 of the rat myelin oligodendrocyte glycoprotein (MOG).</p>

<p>antigen</p>

<p>CNP-53 is a Research Tool for the study of protein interactions, pharmacology and cell biology. It is an activator that interacts with Ligand Receptor and Cell Biology. CNP-53 is a peptide with a molecular weight of 5310.1 Da, which is purified to be 99% pure. This product is suitable for use in research as well as in clinical trials and has been shown to inhibit ion channels and high purity proteins.</p>

<p>Bromoacetamido-dPEG®12-TFP Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Bromoacetamido-dPEG®12-TFP Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Portion of HCMV</p>

<p>Relaxin H2 is a hormone that is produced in the ovaries and has significant interactions with cyclase. It has been shown to bind to the receptor for relaxin and inhibit its activity. Relaxin H2 has been shown to be a potent inhibitor of cardiac growth factor-β1, which may contribute to its anti-fibrotic effects. This drug is also an inhibitor of fatty acid synthesis and can lead to metabolic disorders, such as glomerular filtration rate, by inhibiting the production of natriuretic peptide levels.</p>

<p>Glu-pNA hydrate is a cell-permeant, fluorescently labeled amino acid that selectively binds to ion channels and can be used as a research tool for pharmacology and protein interactions. Glu-pNA hydrate is a high purity product with an antibody activity of less than 0.5% and its CAS number is 1314-77-8. This product has been shown to inhibit the activity of the following proteins: PKCα, phospholipase A2, cyclooxygenase II, and caspase 3. Glu-pNA hydrate also has been shown to activate the following proteins: PKA, PKCβII, PKCγII, PKCδI, PKCεII, PI3KIIIα/β/γ/δ/εIIIa/b/c/d, p38MAPKs, ERK1/2 MAPKs, JNK1/2 MAPK</p>

<p>AIP-III is a peptide that belongs to the group of activators. It binds to the nicotinic acetylcholine receptor, thereby activating it. AIP-III has been shown to cause significant changes in the activity of ion channels and is used as a research tool for pharmacology and protein interactions. AIP-III has been found to be a potent inhibitor of various types of cancer cells in cell culture experiments, although its effects on humans are unknown.</p>

<p>Please enquire for more information about H-Leu-Pro-OH hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

DOTA tris(TBE)-Amido-dPEG®23-Maleimide is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. DOTA tris(TBE)-Amido-dPEG®23-Maleimide is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

TentaGel; is a gelatinous resin, an important support for solid phase synthesis. TentaGel resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol) as shown below. The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix. The TentaGel; S base resins are available with several different derivative choices. The typical capacity range for our TentaGel base resins is 0.2-0.3 meq/g. (90 √ǵm) Substitution Functional Group: -O-CH2-CH2-Br Application: (90 µm)

SH3-domain GRB2-like 2, human, recombinant is a protein that in humans is encoded by the SH3GLB2 gene. This protein is a member of the GRB2/SOS1 protein family and contains a SH3 domain. It has been reported to interact with Sos1 and Grb2, and to act as an activator for Ras-dependent signaling pathways. SH3GLB2 has been shown to be involved in the regulation of ion channels, such as calcium-activated potassium channels, and ligand-gated ion channels such as NMDA receptors. Antibodies against this protein are used as research tools for cell biology or immunoassays. SH3GLB2 has also been shown to inhibit the growth of cancer cells by inhibiting their ability to proliferate and migrate.

<p>Neurofilament Medium Polypeptide Bovine is a freeze-dried preparation of the protein neurofilament medium polypeptide. It is used for the quantitative determination of neurofilaments in spinal cord tissue and for functional studies of neurofilaments in neuronal cells. The protein is purified from bovine spinal cord by fractionation with ammonium sulfate precipitation and desalting on a DEAE-cellulose column, followed by two cycles of freeze-drying. The molecular mass is about 190 kDa. Reconstitute in 0.1 M methylammonium chloride and store at 4°C before use.</p>

<p>IL-1α is a cytokine that belongs to the IL-1 family of cytokines. It has been shown to activate ion channels, bind to receptors, and inhibit ligand binding. IL-1α has been shown to have an anti-inflammatory effect by inhibiting the transcription of pro-inflammatory genes. IL-1α is not active against bacteria or fungi. The anti IL-1alpha (rat) serum was developed for use in research studies involving peptides and other small molecules that interact with IL-1α.</p>

Urocortin 2 (Rat)-EIA Kit (1ea) is an antibody-based sandwich ELISA kit for the quantitative determination of Urocortin 2 in rat serum and other biological fluids. The assay utilizes a monoclonal antibody to Urocortin 2 to capture the target analyte and a biotinylated polyclonal antibody to Urocortin 2 to detect the captured analyte. The amount of Urocortin 2 in samples is determined by measuring the amount of biotin complexed with streptavidin. The Urocortin 2 (Rat)-EIA Kit (1ea) has been designed for use in conjunction with a spectrophotometer or fluorimeter.

Leu-Pro-Leu-Arg-Phe-NH2 diacetate dihydrate is a peptide that is derived from Laminin. It has been shown to inhibit proliferation of human skin cells and induce cell death. Leu-Pro-Leu-Arg-Phe-NH2 diacetate dihydrate also inhibits the production of collagenase, which is an enzyme that breaks down collagen in the skin.

<p>O-6-Methylguanine-DNA Methyltransferase, human, recombinant is a recombinant protein that belongs to the class of proteins and enzymes. It is an enzyme that catalyzes the transfer of methyl groups from S-adenosylmethionine to guanine in DNA. The methylated guanines are recognized by proteins that bind to DNA and inhibit transcription. This enzyme has been shown to be important in the development of cancer cells, which may be due to its ability to inhibit DNA repair.</p>

Endokinin D is a peptide that is derived from the precursor of kininogen. Endokinin D binds to endothelin receptors and activates ion channels, which are proteins that control the flow of ions across cell membranes. It has been shown to be an inhibitor of phospholipase C activation and an activator of potassium channels. It also has high purity and is a research tool for studying cell biology and pharmacology.

<p>This Thyroglobulin VIF Light Tryptic Peptide Standard is useful in protein identification and quantitation studies such as liquid chromatography-tandem mass spectrometry (LC-MS/MS). The use of tryptic peptides overcomes the challenges of quantifying serum thyroglobulin levels using immunoassays through removing the risk of interferences from Thyroglobulin antibodies. Thyroglobulin is a thyroid hormone production substrate and thus an important biomarker for differentiated thyroid cancer.</p>

<p>Peptide H-LSPSFADLFR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-LTPVSPESSSTEEK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-ANALLANG-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-ESGGGGSPGRRRRRRRRRRR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Peptide H-IQVLVEPDHFK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>CMVpp65 - 21 is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-VMTPRTLVL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-EHHG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-LAWHC-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-LPFFSNVTWF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-TSTTVDLK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-QGVEHEASRDEEPR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-VMAPWTLIL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-LESNNYNTYR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-IGLDLPALNMQR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-TVRHPEW-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-PVLDLFRELLNELLEALKQKLK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-GFLSDLLK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-IFFVNPAPPYLWPAHK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Thymosin, beta 10 (human, rat) is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>KLA10 is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

Peptide H-EANQSTLENFLER-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Peptide Ac-SGRGKQGGKAR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Neuromedin-U-23 is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-SFNR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-DLPAPIER-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-DKPTYFE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-EKL-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-VMAPRSLLL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-LQEYTQTILR-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-QYNVTQAFGR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-TGLQEVEVK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-STRQALRPRADGPVG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-DIDDLELTLAK-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

Peptide H-MPAVMSSAQVPR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>H-ELETAYSNLLR-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

Hi-5 is a recombinant, human protein that inhibits the high mobility group box 1 (HMGB1), an inflammatory mediator. HMGB1 is produced by activated macrophages and triggers inflammation reactions in response to tissue injury or infection. Hi-5 can be used as a pharmacological tool for the study of HMGB1-mediated inflammation and as a research tool for the discovery of new drugs that target HMGB1. Hi-5 has been shown to inhibit the interaction between HMGB1 and its receptors, which may be due to its ability to bind to both ligands and receptors of HMGB1.

<p>Peptide H-EHYG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

ATP Synthase Subunit O, Mitochondrial is a recombinant protein that belongs to the ATP synthase subunit family. It has been shown to be an activator of ion channels and receptor. The protein is also able to facilitate the interactions between proteins and ligands. ATP Synthase Subunit O, Mitochondrial has a molecular weight of approximately 44 kDa and an isoelectric point of 9.6. This product can be used as research tool for cell biology, pharmacology, and biochemistry studies.

<p>HIST1H2AG, H2AFP, HIST1H2AI, H2AFC, HIST1H2AK, H2AFD, HIST1H2AL, and H2AFN are histone proteins that are components of the nucleosome. They are involved in regulating gene expression. Histones can be analyzed by a proteomics technique known as TrypTides to identify modifications to the protein's amino acid sequence. The Proteomics Tools Kit provides a number of tools for performing peptide enrichment and analysis of proteins extracted from cells or tissues. In this kit is an MS Calibrator-2 (25nmol) which is used to calibrate mass spectrometers with different capabilities.</p>

An Alpha-2-Macroglobulin heavy tryptic peptide standard for protein identification and quantitation studies. Alpha-2-Macroglobulin is a broad spectrum protease inhibitor which also plays roles in cell migration and in the binding of growth factors and cytokines.

Mannose binding lectin is a host defense protein which has the ability to recognize a variety of infectious agents. This Mannose Binding Lectin Heavy Tryptic Peptide Standard can be used in protein identification and quantitation studies.

Please enquire for more information about Thymosin β10 (human, rat) trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Ras Homolog Enriched in Brain, human, recombinant is a research peptide that is derived from Escherichia Coli. This protein is commonly used in scientific research for various applications. It is highly pure and has been produced using advanced recombinant technology. Ras Homolog Enriched in Brain plays a crucial role in cellular signaling pathways and is involved in numerous biological processes. Its high-quality and purity make it an ideal choice for researchers looking to study the functions and mechanisms of this protein.

<p>Neuromedin U Precursor-Related Peptide 36 (Rat, Mouse) is a peptide that belongs to the group of activator peptides. It is an inhibitor of ion channels and can be used as a research tool in cell biology and pharmacology. Neuromedin U Precursor-Related Peptide 36 (Rat, Mouse) has been shown to activate potassium channels and inhibit sodium currents. This peptide also interacts with receptors and ligands.</p>

<p>MAL-dPEG®4-Glu(TFP Ester)-NH-dPEG®4-Glu(TFP Ester)-NH-m-dPEG®24 is a peptide containing polyethylene glycol (PEG) as spacer to alter their pharmacokinetic properties and pharmodynamics.</p>

This is a recombinant human Leukocyte-Associated Ig-Like Receptor 2 (LAIR2) protein. It is an activator of the LAIR2 receptor, which is a member of the immunoglobulin superfamily. LAIR2 is expressed on activated T cells and NK cells. This protein also can interact with other receptors, such as CD4 and FcRγ, to inhibit ion channels and activate cell signaling pathways. LAIR2 has been shown to be involved in immune responses, including antibody production and cytokine release by activated lymphocytes.

TFP-dPEG®4-Biotinidase Resistant Biotin is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. TFP-dPEG®4-Biotinidase Resistant Biotin is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

An Alpha-2-Macroglobulin light tryptic peptide standard for protein identification and quantitation studies. Alpha-2-Macroglobulin is a broad spectrum protease inhibitor which also plays roles in cell migration and in the binding of growth factors and cytokines.

<p>Peptide H-NVEDLSGGELQR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Please enquire for more information about Atrial natriuretic factor (1-28) (human) acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

8-Oxoguanine DNA glycosylase is a glycosylase enzyme that repairs the 8-oxoG DNA base. It has been purified from human and Escherichia coli cells and recombinantly produced in E. coli. The enzyme has a molecular mass of about 42 kDa and is composed of two polypeptide chains with an apparent molecular weight of 17 kDa each. 8-Oxoguanine DNA glycosylase has been shown to have a broad substrate range, including both oxidized and reduced forms of 8-oxoG, as well as other oxidized purine bases such as 7,8-dihydrothymine (8-hydroxyguanine) and 5,6-dihydrothymine (5,6-dihydroxyguanine). The enzyme catalyzes the removal of the damaged base from the DNA backbone without any concomitant chemical changes in the sugar or phosphate groups

<p>This product is a Fibrinogen Light Tryptic Peptide Standard for protein identification and quantitation. Fibrinogen is glycoprotein produced by the liver and is a precursor to fibrin which makes up blood clots.</p>

Please enquire for more information about L-Lysyl-L-cysteine trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

GHRP 4 TFA is a synthetic hexapeptide, which is derived from non-natural amino acids, with a primary function of stimulating the secretion of growth hormone (GH). The source of this peptide is chemical synthesis, using solid-phase peptide synthesis techniques that allow precise chain assembly. The mode of action of GHRP 4 involves binding to growth hormone secretagogue receptors (GHS-R) located in the pituitary gland and hypothalamus. This interaction triggers the release of endogenous growth hormone by mimicking the action of ghrelin, a natural endogenous ligand.In scientific research, GHRP 4 TFA is utilized to explore the physiological and cellular pathways involved in GH release and its systemic effects. Applications include studying metabolic regulation, muscle growth, and cellular proliferation. Additionally, its role in aging and age-related disorders makes it a valuable tool in gerontological studies. The peptide's ability to modulate endocrine responses is of interest for developing therapeutic approaches in GH deficiency and other metabolic disorders. However, research into its full biological effects and potential clinical applications is ongoing, emphasizing its utility in experimental and preclinical settings.

GPCD peptide; synthetic substrate that mimics the DPP-IV (dipeptidyl peptidase IV) natural substrate. 95%, TFA salt.

<p>Please enquire for more information about IgA1 Hinge Region Peptide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Amyloid Beta-Protein (Human, 1-40) Antiserum is an antibody, which is a protein that recognizes and binds to a specific antigen. The Amyloid Beta-Protein (Human, 1-40) Antiserum can bind to amyloid beta protein in the brain and trigger immune system cells to clear it from the body. This antibody can also be used as a research tool for studying the structure of amyloid beta protein and how it affects human cells.

Kallidin is a peptide that has regulatory effects on tissue remodeling, inflammatory responses, and the growth of new blood vessels. It is found in a number of tissues, including extracellular matrix proteins, where it acts as a regulator. Kallidin has been shown to regulate kinins, which are hormones that are responsible for the regulation of inflammation. Kallidin also regulates collagen and fibrinogen production by stabilizing these proteins. This peptide also induces leukocyte recruitment and polymorphonuclear leukocytes (PMN) activity. Kallidin can stimulate growth factor production and may play an important role in the stabilization of matrix proteins such as fibronectin.

<p>EPGN Human is a research tool that is an activator, ligand, and receptor. It is also used in Cell Biology as an antibody and an ion channel. EPGN Human is used in pharmacology as a peptide. EPGN Human has high purity and can be used in Life Science for protein interactions or as an inhibitor.</p>

Please enquire for more information about Amyloid β (1-42) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Insulin-like 5 (INSL5) is a protein that in humans is encoded by the INSL5 gene. It belongs to the insulin family of proteins and has been shown to have a role in various biological functions. INSL5 binds to the insulin receptor, which induces apoptosis in cancer cells by inhibiting cyclin-dependent kinase activity and inducing cell cycle arrest. The expression of INSL5 can be used as a diagnostic marker for cervical cancer and may also be used as a potential biomarker for cancer tissues.

Hepatitis E virus (HEV) is a virus that infects the liver and causes hepatitis. Recombinant HEV ORF2 protein was produced by recombinant techniques in Escherichia coli. The recombinant HEV ORF2 protein has been shown to be immunogenic in mice, rabbits, and humans. Immunodominant epitopes were found at amino acid positions 448-456 and 468-480.

<p>Gap19 is a protein that regulates cell growth and has been implicated in cancer. Gap19 is a member of the myosin II family of proteins, which are involved in muscle contraction. Gap19 binds to calmodulin and is localized to the sarcomere region of cardiac ventricular myocytes. Gap19 has been shown to be a specific ligand for toll-like receptor 4 (TLR4). The binding of Gap19 leads to an increase in intracellular reactive oxygen species (ROS) levels, activation of transcription factors, and induction of inflammatory responses. These findings suggest that Gap19 plays an important role in regulating inflammatory diseases. Gap19 also has a biochemical function as a specific antibody for collagen, which is used to study cellular reactions involving collagen.</p>

<p>Human GH (1-43) ELISA Kit (1ea) is a sandwich enzyme-linked immunosorbent assay for the quantitative measurement of human GH in serum. It has demonstrated cross-reactivity with monkey, rat, and mouse GH, but not bovine or porcine GH.</p>

Hemoglobin, α 2, human, recombinant is a protein that belongs to the group of hemoglobins. It is a recombinant protein that has been produced by inserting the human alpha-2 globin gene into a bacterial expression system. This product can be used as an ion channel probe, an activator of G-protein coupled receptors or as an inhibitor of ligand binding to receptors. It has been shown to interact with a variety of peptides and proteins. Hemoglobin, α 2, human, recombinant can be used in research for cell biology and pharmacology studies.

Ferredoxin-1 is a peptide that belongs to the group of activators. It can be used as an inhibitor, or as a receptor or ligand in pharmacological experiments. Ferredoxin-1 has been shown to inhibit ion channels and protein interactions. This protein may also have implications for cell biology and is used as a research tool for life science. The CAS number for ferredoxin-1 is 107899-38-2.

Lipid A is a bacterial endotoxin that activates macrophages and dendritic cells, which in turn activate T-cells. It is a ligand for the CD14 receptor, which is a pattern recognition molecule found on macrophages and dendritic cells. Lipid A also binds to the Toll-like receptor 4 (TLR4) on host cells, initiating an inflammatory response. Lipid A has been used as a research tool to study cell biology related to activation of macrophages and dendritic cells leading to cytokine production. This activator has also been used as a ligand in antibody studies, ion channel studies, protein interactions, pharmacology experiments with peptides, and life science research.

EREG Human is a cytokine that belongs to the group of proteins. It is an interleukin-1 receptor antagonist (IL-1Ra) that binds to IL-1 and prevents it from binding with its receptors. EREG Human has been shown to be effective in treatment of inflammatory diseases such as Crohn's disease, rheumatoid arthritis, and ulcerative colitis.

<p>Anti Nociceptin / Orphanin FQ (Human, Rat) Serum is a peptide that belongs to the family of orphanin FQ peptides. It has been shown to activate ion channels and ligand-gated channels. Anti Nociceptin / Orphanin FQ (Human, Rat) Serum is a high purity, pharmacology research tool for use in cell biology and receptor studies.</p>

Anti Humanin Serum is a research tool that can be used as a pharmacological reagent or as a research tool. It is an antibody that can be used to study protein interactions, such as receptor-ligand binding, and the effects of peptides on ion channels. This product is composed of high purity humanin antibodies with no detectable cross-reactivity with other proteins.

<p>Dihydrofolate reductase is an enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. It belongs to a family of metalloenzymes that employ NADPH as a cofactor and are involved in one-carbon metabolism. Dihydrofolate reductase has been shown to interact with a number of other proteins, including peptides, cell biology, and receptor. This enzyme is also used as an inhibitor for research purposes.</p>

This enzyme belongs to the family of isomerases, and is a type of glycosylated enzyme. The recombinant DNA topoisomerase-I has been expressed in E. coli cells, purified through chromatography and characterized by mass spectroscopy. It is an enzyme that catalyzes the breakage and rejoining of one DNA strand in order to relieve torsional strain between two strands. In addition to its function as an enzyme, it can be used as a food additive or a technique for molecular biology.

Anti Galanin (Porcine) Serum is a research tool that is used to activate, bind, and inhibit the ligand-receptor interactions. It is also used for the study of ion channels and cell biology. Anti Galanin (Porcine) Serum can be used as an antibody or as a peptide in pharmacology studies. The protein interactions are used in life science research, as well as for inhibitor studies.