Peptides

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of TAF3 antibody, catalog no. 70R-9077</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of ATG4D antibody, catalog no. 70R-9614</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PRDX5 antibody, catalog no. 70R-5755</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SLC22A1 antibody, catalog no. 70R-1736</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of GALNT5 antibody, catalog no. 70R-7239</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF683 antibody, catalog no. 70R-8156</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of TUT1 antibody, catalog no. 70R-8371</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of Abra antibody, catalog no. 70R-9195</p>

A synthetic peptide for use as a blocking control in assays to test for specificity of GPR174 antibody, catalog no. 70R-10017

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of BTNL8 antibody, catalog no. 70R-6390</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of WDR4 antibody, catalog no. 70R-2223</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of MPP3 antibody, catalog no. 70R-2662</p>

A synthetic peptide for use as a blocking control in assays to test for specificity of ANXA5 antibody, catalog no. 70R-1668

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CD22 antibody, catalog no. 70R-9914</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of KCNK3 antibody, catalog no. 70R-1536</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of GSTA4 antibody, catalog no. 70R-2577</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PDCD8 antibody, catalog no. 70R-6013</p>

A synthetic peptide for use as a blocking control in assays to test for specificity of PPP3CA antibody, catalog no. 70R-4112

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of ETV1 antibody, catalog no. 70R-7876</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SLC7A7 antibody, catalog no. 70R-6771</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PCDHA5 antibody, catalog no. 70R-6167</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of NINJ1 antibody, catalog no. 70R-6116</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of RUNDC2A antibody, catalog no. 20R-1267</p>

A synthetic peptide for use as a blocking control in assays to test for specificity of CYP1A1 antibody, catalog no. 70R-7256

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of MTR antibody, catalog no. 70R-5231</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of Urgcp antibody, catalog no. 70R-9383</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of UBXD2 antibody, catalog no. 20R-1265</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of LOC285033 antibody, catalog no. 70R-3365</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of GOLGA5 antibody, catalog no. 70R-6969</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of GEM antibody, catalog no. 70R-5974</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF700 antibody, catalog no. 70R-8989</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of FBXO36 antibody, catalog no. 70R-3784</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SFRS10 antibody, catalog no. 70R-1421</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CACNB3 antibody, catalog no. 70R-1512</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of BNIP1 antibody, catalog no. 70R-9800</p>

A synthetic peptide for use as a blocking control in assays to test for specificity of KCNN4 antibody, catalog no. 70R-5153

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of Ercc1 antibody, catalog no. 70R-9364</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CCDC146 antibody, catalog no. 70R-4540</p>

A synthetic peptide for use as a blocking control in assays to test for specificity of HIST1H2AE antibody, catalog no. 70R-10218

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of GTSE1 antibody, catalog no. 70R-5612</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of RFTN2 antibody, catalog no. 70R-4543</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of RDBP antibody, catalog no. 70R-4683</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of ATP4B antibody, catalog no. 70R-6951</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of LIG1 antibody, catalog no. 70R-5620</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of EIF4ENIF1 antibody, catalog no. 70R-3586</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PGM3 antibody, catalog no. 70R-4450</p>

A synthetic peptide for use as a blocking control in assays to test for specificity of CCND1 antibody, catalog no. 70R-7984

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of ACTR2 antibody, catalog no. 70R-1197</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of DDX3X antibody, catalog no. 70R-4688</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SLC35F3 antibody, catalog no. 70R-6807</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of C19orf24 antibody, catalog no. 70R-4955</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SERPINA5 antibody, catalog no. 70R-5417</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CTAG1B antibody, catalog no. 70R-10169</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of TH antibody, catalog no. 70R-7854</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of KIFC3 antibody, catalog no. 70R-5600</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PXT1 antibody, catalog no. 70R-4253</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of UGT2A3 antibody, catalog no. 70R-7206</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PPIE antibody, catalog no. 70R-1435</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of RPL18 antibody, catalog no. 70R-5007</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SLA/LP antibody, catalog no. 70R-4725</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of DDX27 antibody, catalog no. 70R-1385</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of AFAP1 antibody, catalog no. 70R-3533</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of HSPA9 antibody, catalog no. 70R-7827</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of NONO antibody, catalog no. 70R-1315</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of NRCAM antibody, catalog no. 70R-6388</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of TPTE antibody, catalog no. 70R-5655</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF266 antibody, catalog no. 70R-8084</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of KIF23 antibody, catalog no. 70R-5544</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CACNA1I antibody, catalog no. 70R-5133</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of HS3ST6 antibody, catalog no. 70R-2842</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of DNASE2B antibody, catalog no. 70R-5280</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PABPC1 antibody, catalog no. 70R-4653</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CD200R1 antibody, catalog no. 70R-9902</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of FZD9 antibody, catalog no. 70R-7131</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of RHBG antibody, catalog no. 70R-7321</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SLC9A1 antibody, catalog no. 70R-7268</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SCYL3 antibody, catalog no. 70R-3018</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of Bnip3l antibody, catalog no. 70R-9618</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of HPD antibody, catalog no. 70R-2553</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CBLL1 antibody, catalog no. 20R-1225</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of Uhmk1 antibody, catalog no. 70R-8494</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of TRIM17 antibody, catalog no. 20R-1091</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of MKNK1 antibody, catalog no. 70R-10043</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF364 antibody, catalog no. 70R-2797</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of HLA-F antibody, catalog no. 70R-6432</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of HSD3B1 antibody, catalog no. 70R-7092</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of AKR1C1 antibody, catalog no. 70R-10004</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of OR2W1 antibody, catalog no. 70R-9893</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of HSPB1 antibody, catalog no. 20R-1061</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of NTRK3 antibody, catalog no. 70R-7122</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of LOC653428 antibody, catalog no. 70R-9057</p>

<p>Agitoxin 2 is a peptide with high resistance to the proteolytic activity of various enzymes, including trypsin, pepsin, and chymotrypsin. Agitoxin 2 is a structural analogue of the acetylcholine receptor agonist carbamylcholine. It binds to the alpha subunit of the nicotinic acetylcholine receptor and inhibits its activation by acetylcholine. Agitoxin 2 has been shown to be effective in animal models for autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. Agitoxin 2 also has an analgesic effect in animals. The molecule's ability to inhibit the release of inflammatory cytokines may be due to its inhibition of transcription-polymerase chain reaction (PCR).</p>

<p>Cathepsin-D is a protease enzyme that belongs to the family of aspartic proteases. It is involved in the degradation of proteins, lipids, and carbohydrates. Cathepsin-D can be found in a variety of tissues, including lung, pancreas, and brain. Inhibition assays have been used to determine the inhibition activity against human cathepsin-D.</p>

Please enquire for more information about H-2kb tetramer peptide - G4 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Tryptic peptide

<p>98%. TFA salt. OVA 257-264 (H-2Kb) is an epitope of ovalbumin.</p>

A synthetic snake venom peptide, sourced from the Green Mamba, Dendroaspis angusticeps. It can be applied as a specific ligand for Muscarinic Acetylcholine Receptor-4 (M4) and this product is available as a 0.1mg vial with disulfide bonds between Cys3- Cys24, Cys17- Cys42, Cys46- Cys57, and Cys58- Cys63.

<p>Peptide T is a synthetic peptide that has been shown to inhibit the activity of protein kinase C. This inhibition may be due to its ability to bind with high affinity and specificity to a site on the receptor protein. Peptide T is a research tool used in studies of cell biology, pharmacology, and physiology. It has been used as an inhibitor for studies of ion channels and has also been used as an activator for studies of receptor-ligand interactions. Peptide T is also known by its CAS number, which is P25657-1-2.</p>

<p>Z-Arg-OBzl(p-NO2) hydrobromide is a research peptide that is commonly used as an enzyme substrate in various biochemical studies. It is widely utilized in the field of molecular biology and biochemistry for its ability to mimic specific enzymatic reactions. This compound is highly pure and has been extensively tested for its quality and reliability. Researchers rely on Z-Arg-OBzl(p-NO2) hydrobromide to accurately measure enzyme activity and understand the mechanisms behind various biological processes. With its precise composition and consistent performance, this research peptide is an essential tool for scientists conducting cutting-edge research in the field.</p>

<p>CBZ-N-Amido-dPEG®4-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. CBZ-N-Amido-dPEG®4-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>The IL-3R is a cytokine receptor that binds to the interleukin 3 (IL-3) molecule. The protein has a molecular weight of approximately 40 kDa and consists of two extracellular immunoglobulin-like domains, a transmembrane domain, and an intracellular tyrosine kinase domain. The IL-3R is expressed on hematopoietic stem cells, progenitor cells, erythrocytes, mast cells, neutrophils, lymphocytes and macrophages.</p>

<p>Mambalgin-1 is a peptide that can be used as a research tool to study the function of ion channels and receptor proteins. It is an activator of potassium ion channels, which are involved in the regulation of cell membrane potential. Mambalgin-1 also binds to serotonin receptors, which are involved in the transmission of nerve impulses. The peptide's affinity for different types of receptors suggests it may have therapeutic potential for treating disorders such as depression and schizophrenia.</p>

<p>SPAI-1 is a protein that belongs to the group of activator proteins. It is an activator of the N-type calcium channels. SPAI-1 interacts with the receptor and peptides, which are involved in signal transduction pathways. SPAI-1 has been shown to be a high purity ion channel ligand that can be used as a research tool for cell biology and pharmacology studies.</p>

<p>[Pyr1]apelin-13 (human) (CAS: 217082-60-5)</p>

<p>Schizophrenia Related Peptide is a research tool that can be used to study ion channels and receptors. It is an artificial peptide that has the same amino acid sequence as the part of the human brain that is believed to be responsible for schizophrenia. The Schizophrenia Related Peptide can bind to cell membranes and inhibit protein interactions, which may lead to new pharmacological treatments for schizophrenia.</p>

<p>Portion of EBV</p>

<p>Thrombin Receptor Activator Peptide 6 (TRAP-6), also called Selective Protease-Activated Receptor 1 (PAR-1) Agonist, is an hexapeptide fragment of the thrombin receptor (residues 42-47).</p>

<p>APYTFGQGTK peptide is a sequence from light chain of Adalimumab monoclonal antibody. Due to its universal location in Adalimumab antibody, APYTFGQGTK is used as a specific signature peptide for the quantitation of Adalimumab. Indeed, proteomic studies allows quantification of proteins in blood samples.<br>What is Adalimumab?<br>Adalimumab corresponds to a therapeutic monoclonal antibody. It is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor. This drug is frequently known as Humira.</p>

<p>A synthetic snake toxin peptide sourced from the Green Mamba, Dendroaspis angusticeps. It is an agonist for Muscarinic Acetylcholine Receptor-1 (M1) and has disulfide bonds between Cys3-Cys24, Cys17-Cys42, Cys46-Cys58, and Cys59-Cys64. This product is available as a 0.1mg vial.</p>

B2M (B 2 microglobulin) is a major component of the MHC class I molecule. The B2M calibrator-3 is a 25nmol/mL solution of B2M, which is used as a calibration standard for proteomics and Biologically Active Peptides. The calibrator-3 contains B2M in 0.1% formic acid at pH 3.5. The peptide TrypTides can be used to inhibit trypsin activity, which may be useful in proteomics experiments involving peptide cleavage.

<p>Synthetic product of the Hepcidin peptide hormone. Hepcidin in rats is a peptide hormone that plays a key role in the regulation of iron metabolism in the body. Like hepcidin in humans and other mammals, rat hepcidin is produced by the liver and secreted into the bloodstream, where it interacts with other proteins to control the uptake, storage, and distribution of iron.<br>Rat hepcidin is structurally similar to human hepcidin, with 88% sequence identity. It shares many of the same functional properties as human hepcidin, including the ability to bind to ferroportin, a protein that facilitates the export of iron from cells into the bloodstream, and to inhibit its activity.<br>In rats, hepcidin expression is regulated by a variety of factors, including iron status, inflammation, and erythropoietic signals. Studies in rats have shown that alterations in hepcidin levels can lead to changes in iron metabolism and the development of iron-related disorders, such as anemia and iron overload.<br>This product may be useful for the study of hepcidin biology and the regulation of iron metabolism in mammals. It can also provided valuable insights into the mechanisms of iron homeostasis and the development of iron-related diseases in humans.</p>

<p>Blocker of P/Q-type calcium channel (Cav2.1)</p>

<p>ASIC1a/1b agonist</p>

<p>Slowing of Nav1.2, Nav1.4 and Nav1.7 channels' inactivation</p>

<p>Biotin-MAGE-A1 (278-286) is the N-ter biotinylated version of MAGE-A1 (278-286). Biotin-MAGE-A1 (278-286) can be used in the analysis of antigen-specific T cells. MAGE-A1 protein:<br>MAGE-A1 (278-286) is an epitope of Melanoma Antigen Gene A1 expressed by tumors of different histological types such as on the surface of breast carcinoma cell and is a Cancer/Testis Antigens (CTA). MAGE-A1 is a tumor antigen expressed in 40% of melanoma and contains epitope for binding HLA-A*02:01 molecules and that are recognized by cytotoxic T cells.<br>Applications of MAGE-A1 (278-286):<br>MAGE-A1 (278-286) is used to stimulate specific cytotoxic T cells in PBMCs and to analyze by ELISPOT peptide epitope specificity and cytokine production like IFN-γ. Immunogenicity of MAGE-A1 (278-286) raised the possibility of developing anticancer immunotherapies or vaccinations. MAGE-A1 is also expressed in lung adenocarcinoma and studies suggest that MAGE-A1 may serve to develop Chimeric Antigen Receptor (CAR) T cell therapy using lentiviral vector and show an encouraging tumor-inhibitory efficacy.<br>Sequence: Biotin-KVLEYVIKV</p>

Cyclotide

<p>Selective blocker of muscular nACh receptors</p>

<p>Human beta-defensin-2 (hBD-2), also known as skin-antimicrobial peptide 1 (SAP1) is a cysteine-rich cationic antimicrobial peptide of 41 amino acids. It was originally isolated from skin cells of psoriasis patients. hBD-2, which belongs to the defensin family, is implicated in the innate immunity thanks to its antimicrobial activity. Thus, β-defensins can play a role at the cutaneous level by limiting the use of antibiotics in severe burns and disease like psoriasis. Moreover, at the pulmonary level, defensins might be involved in the resorption of the infection in cases of cystic fibrosis.<br>hBD-2 is produced after stimulation of epithelial cells following their contact with some organisms like Gram-negative bacteria and Candida Albicans, fungus or cytokines such as TNF-alpha and IL-1 beta. This antimicrobial activity was shown to be microbicidal at concentrations greater than 1 µM and was lethal for E.Coli and pseudomonas (LD90 : 10 mg/mL) and Candida Albicans (LD90 : 25 mg/mL). Besides its antimicrobial activity, hBD-2 also exhibits proinflammatory properties as chemoattractants for memory T-cells, immature dendritic cells, mast cells and neutrophils.<br>hBD-2 has also demonstrated inhibitory activity of the voltage-gated potassium channel Kv1.3 at picomolar concentration. Kv1.3 are overexpressed by T-cells in case of autoimmune disorders.</p>

<p>Overlaping biotin-peptide library of Spike Omicron mutant. 15 amino acids per peptide with offset 11. Each peptide is N-ter biotinylated. Purity crude. 1 peptide per well.</p>

<p>Biotin-SARS-CoV-2 Spike RBM 480-496 (Biotin-LC) peptide is the biotinylated version of SARS-CoV-2 Spike RBM 480-496 peptide. SARS-CoV-2 Spike RBM 480-496 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Motif (RBM). Biotin-SARS-CoV-2 Spike RBM 480-496 peptide is useful for vaccine development and for structure-activity relationship studies<br>SARS-CoV-2 Spike (S) glycoprotein<br>Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells.<br>With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane.<br>SARS-CoV-2 Spike RBM:<br>The receptor-binding domain in SARS-CoV-2 Spike protein contains a receptor-binding motif RBM. SARS-CoV-2 Spike RBM is the main functional motif in RBD and allows contacts between the S protein and the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry.</p>

TTX-S selective blocker

<p>SB-peptide offers the scrambled version of MAGE-A p248V9. RQYVELPYV can be used as a negative control of MAGE-A p248V9 studies.<br>SB-peptide offers also MAGE-A p248V9 (see section MAGE-A p248V9)).<br>MAGE-A protein:<br>MAGE-A p248V9, also kwon as multi-MAGE-A (YLEYRQVPV) is an epitope of Melanoma Antigen Gene expressed by tumors of different histological types and is a Cancer/Testis Antigens (CTA). Type of MAGE-A expressed in tumors cells varies according to the type of tumor. Targeting epitopes shared by all MAGE-A antigens would be interest in immunotherapy against a broad spectrum of cancers.<br>Applications of MAGE-A p248V9 (multi-MAGE-A) :<br>MAGE-A p248V9 is very useful because it could generate an HLA-A*02:01-restricted CTL response and shared by MAGE-A1,-A2,-A3,-A4,-A6,-A10 and -A12. MAGE-A p248V9 is used to stimulate specific cytotoxic T lymphocytes (CTL) in PBMCs and then to analyze CTL response especially the cytokine production by ELISPOT assay.<br>Sequence : RQYVELPYV</p>

<p>Hydrogels are a class of materials that are promising candidates for use in soft tissue and bone engineering. Hydrogels have a high water content, suitable viscoelasticity and biocompatibility.<br>Using hydrogel can help for biomedical applications such as tissue engineering, encapsulation methods for cells and biomolecules, drug delivery or some injectable delivery vehicles for therapeutics.<br>However, hydrogels are mainly used for their antimicrobial properties which are due to the surface of the hydrogel, having the capacity to disrupt negatively-charged bacterial membrane via electrostatic interactions. Antimicrobial activities of hydrogels were shown against gram-positive bacteria such as S.Aureus and gram-negative bacteria like E.Coli.<br>The main interest of employing hydrogels is its biocompatibility in vitro and in vivo which permits to hydrogel to be able to perform an appropriate host response in a specific situation.<br>It also seems that the antimicrobial peptide-based hydrogels are very effective against biofilm adhesion likely due to the physical mode of action involving bacterial membrane disruption.<br>Max 1 is the first MAX peptide described, a 20-amino acid peptide designed to understand peptide intramolecular folding. Max 1 is useful for making hydrogels owing to its ability to change its structural conformation according to environmental changes.<br>Max 1 stays unfolded and soluble in a low ionic strength aqueous solution (10 mM NaCl) at neutral pH however with a high salt concentration (150 mM NaCl) or a higher pH, Max 1 folds into an amphiphilic β-hairpin conformation that can self-assembles to form a network of fibrils that conducts to the formation of a hydrogel hairpin.</p>

SB-peptide offers the scrambled version of MAGE-A2 (157-166). VLVYFQEIGL can be used as a negative control of MAGE-A2 (157-166) studies. SB-peptide offers also MAGE-A2 (157-166) (see section MAGE-A2 (157-166)). MAGE-A2 protein: MAGE-A2 (157-166) is an epitope of Melanoma Antigen Gene A2 and is one of the most Cancer-Testis Antigens (CTA) overexpressed in tumors of different histological types, such as prostate cancer. Type of MAGE-A expressed in tumors cells varies according to the type of tumor. The expression of MAGE-A2 causes the proliferation of prostate cancer cells and decreases the chemosensitivity. Applications of MAGE-A2 (157-166): MAGE-A2 (157-166) is used to stimulate specific immune response, cytotoxic T cell response and to analyze the cytokine production in PBMCs by ELISPOT assay. In transgenic mouse, it has been demonstrated that MAGE-A2 (157-166) was capable of eliciting a CTL response presented by HLA-A*02:01 molecules. MAGE-A2 (157-166) has been reported to elicit CTL that could lyse tumor cell expressing both HLA-A*02:01 and MAGE-A2 by stimulation of peripheral blood mononuclear cells (PBMCs) with MAGE-A2 (157-166). Sequence : VLVYFQEIGL

<p>Selective blocker of N-type calcium channels</p>

<p>Selective blocker of Kv3.4 and potent Nav1.7 activator</p>

<p>SB-peptide offers the scrambled version of MAGE-A1 (278-286). ELIVKVYKV can be used as a negative control of MAGE-A1 (278-286) studies.<br>SB-peptide offers also MAGE-A1 (278-286) (see section MAGE-A1 (278-286)).<br>MAGE-A1 protein:<br>MAGE-A1 (278-286) is an epitope of Melanoma Antigen Gene A1 expressed by tumors of different histological types such as on the surface of breast carcinoma cell and is a Cancer/Testis Antigens (CTA). MAGE-A1 is a tumor antigen expressed in 40% of melanoma and contains epitope for binding HLA-A*02:01 molecules and that are recognized by cytotoxic T cells.<br>Applications of MAGE-A1 (278-286):<br>MAGE-A1 (278-286) is used to stimulate specific cytotoxic T cells in PBMCs and to analyze by ELISPOT peptide epitope specificity and cytokine production like IFN-γ. Immunogenicity of MAGE-A1 (278-286) raised the possibility of developing anticancer immunotherapies or vaccinations. MAGE-A1 is also expressed in lung adenocarcinoma and studies suggest that MAGE-A1 may serve to develop Chimeric Antigen Receptor (CAR) T cell therapy using lentiviral vector and show an encouraging tumor-inhibitory efficacy.<br>Sequence : ELIVKVYKV</p>

APYTFGQGTK peptide is a sequence from light chain of Adalimumab monoclonal antibody. Due to its universal location in Adalimumab antibody, Stable Isotope Labeled (SIL) APYTFGQGTK is used as a specific signature peptide for the quantitation of Adalimumab.

<p>α9α10 and α7 nAChRs channels discrimination</p>

SA currents blocker

<p>Bombesin (BBN) is a 14-amino acid neuropeptide originally isolated from the skin of Bombina bombina. The bombesin-related family comprises three other peptides, the amphibian homologs alytesin and Neuromedin C (NMC), and the mammalian peptide named Gastrin-Releasing Peptide (GRP). Bombesin and bombesin-related peptides are characterized by a region of homology at the carboxy-terminus ending with Gly-His-Leu-Met-NH2, in which resides their biological activity.<br>Bombesin is active in mammals and affects a broad range of biological functions including smooth muscle contraction, cell growth, blood pressure, plasma glucose, as well as gastric secretions2. These effects are mediated by the interaction of Bombesin peptide with G protein-coupled receptors (GPCRs) called bombesin receptors that are well represented in the gastrointestinal tract and in the central nervous system (CNS).<br>Bombesin peptide is a potent natural agonist of the mammalian Gastrin Releasing Peptide Receptor (GRPR) also know as bombesin receptor 2 (BB2), whose endogenous ligand is the Gastrin Releasing Peptide (GRP). Bombesin has demonstrated a high affinity for human Gastrin-Releasing Peptide Receptors (hGRPR) in both human cells containing native GRP receptors and murine cells stably expressing human GRP receptors (IC50 = 0.17±0.01 nM and 0.07 ± 0.01 nM, respectively).There is increased interest in targeting the bombesin receptors to explore their roles in pathophysiological processes, and for diagnostic imaging of human cancers over-expressing Gastrin-Releasing Peptide Receptors (GRPR), such as prostate, breast, and small-cell lung carcinoma. Bombesin peptide is investigated as targeting peptide to deliver radiotracers and therapeutic agents into tumors. Moreover, many synthetic agonist analogs of the biologically active COOH terminus of bombesin-related peptides have been synthesized to develop more metabolically stable and selective ligands for Bombesin receptors.</p>

<p>The Nucleocapsid Protein (N-protein), also called coronavirus nucleocapsid (N), is the most abundant protein in coronavirus. It is a structural protein that forms complexes with genomic RNA, interacts with the viral membrane protein during virion assembly and plays a critical role in enhancing the efficiency of virus transcription and assembly.</p>

<p>Secondary SIL peptide for Dupilimab detection and quantification</p>

<p>Peptide named cardiac myosin heavy chain (Myhc)-α 334–352 induces autoimmune myocarditis in mice bearing H-2 allele IAk.</p>

Overlaping peptide library of Spike Omicron mutant. 15 amino acids per peptide with offset 11. Purity crude. 1 peptide per well.

<p>Clickable Arg9 peptide.</p>

<p>Biotin-SARS-CoV-2 Spike RBD 336-347 peptide is the biotinylated version of SARS-CoV-2 Spike RBD 336-347 peptide. SARS-CoV-2 Spike RBD 336-347 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Domain (RBD). Biotin-SARS-CoV-2 Spike RBD 336-347 peptide is useful for vaccine development and for structure-activity relationship studies<br>SARS-CoV-2 Spike (S) glycoprotein<br>Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells.<br>With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane.<br>SARS-CoV-2 Spike RBD:<br>The receptor-binding domain in SARS-CoV-2 Spike protein allows binding to the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry.</p>

SARS-CoV-2 Spike RBM 438-458 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Motif (RBM). SARS-CoV-2 Spike RBM 438-458 peptide is useful for vaccine development and for structure-activity relationship studies SARS-CoV-2 Spike (S) glycoprotein Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells. With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane. SARS-CoV-2 Spike RBM: The receptor-binding domain in SARS-CoV-2 Spike protein contains a receptor-binding motif RBM. SARS-CoV-2 Spike RBM is the main functional motif in RBD and allows contacts between the S protein and the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry. SB-PEPTIDE also offers SARS-CoV-2 Spike RBM 438-458 (Biotin-LC) peptide

<p>Biotin-SARS-CoV-2 Spike RBD 348-357 peptide is the biotinylated version of SARS-CoV-2 Spike RBD 348-357 peptide. SARS-CoV-2 Spike RBD 348-357 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Domain (RBD). Biotin-SARS-CoV-2 Spike RBD 348-357 peptide is useful for vaccine development and for structure-activity relationship studies<br>SARS-CoV-2 Spike (S) glycoprotein<br>Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells.<br>With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane.<br>SARS-CoV-2 Spike RBD:<br>The receptor-binding domain in SARS-CoV-2 Spike protein allows binding to the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry.</p>

<p>Blocker of Kv2 channels</p>

<p>Selective antagonist of the alpha(1A)-adrenoceptor</p>

<p>Blocker of Nav1.1 / 1.2 / 1.3 / 1.4 / 1.6 / 1.7</p>

<p>Influenza virus-specific hemagglutinin<br>Flu-HA-B (306-318) is a short part of Influenza hemagglutinin (HA). Influenza hemagglutinin is glycoprotein found on the surface of influenza viruses. HA allows Influenza virus to bind factor on the surface of the cell membrane. HA is also responsible for the membrane fusion with the viral envelope.<br>Flu-HA-B (306-318) DRB1*01:01<br>Flu-HA-B (306-318) is a classical antigenic peptide which is used as positive control to bind DRB1*01:01 for peptide/MHC-binding assay. It has been demonstrated the ability of HLA-DRB1*01:01 to present Flu-HA-B (306-318).</p>

<p>Kv and SK channels blocker</p>

<p>SARS-CoV-2 Spike RBD 352-365 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Domain (RBD). SARS-CoV-2 Spike RBD 352-365 peptide is useful for vaccine development and for structure-activity relationship studies<br>SARS-CoV-2 Spike (S) glycoprotein<br>Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells.<br>With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane.<br>SARS-CoV-2 Spike RBD:<br>The receptor-binding domain in SARS-CoV-2 Spike protein allows binding to the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry.<br>SB-PEPTIDE also offers SARS-CoV-2 Spike RBD 352-365 (Biotin-LC) peptide</p>

SARS-CoV-2 Spike (S) glycoprotein: Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein in a class I fusion protein that allows the virus to enter host cells. Variants package available: Some proteins of Sars-CoV-2 are identified as leading targets for COVID-19 therapies. SB-PEPTIDE offers a special pack pre-made peptide libraries of Spike protein including peptides from COVID-19 variants: UK COVID-19 variant B.1.1.7, South Africa COVID-19 variant B.1.351, Brazil COVID-19 variant B.1.1.248. SB-PEPTIDE offers additional plate containing only peptides with Spike S protein mutation of COVID-19 B.1.1.7, B.1.3.5.1 and B.1.1.248 (cited below). Variants package and Spike (S) glycoprotein peptide library can be used for T-cell assays, immune monitoring, antigen specific T-cell stimulation, T-cell expansion and cellular immune response.

<p>Biotin-SARS-CoV-2 Spike RBM 450-473 peptide is the biotinylated version of SARS-CoV-2 Spike RBM 450-473 peptide. SARS-CoV-2 Spike RBM 450-473 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Motif (RBM). Biotin-SARS-CoV-2 Spike RBM 450-473 peptide is useful for vaccine development and for structure-activity relationship studies<br>SARS-CoV-2 Spike (S) glycoprotein<br>Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells.<br>With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane.<br>SARS-CoV-2 Spike RBM:<br>The receptor-binding domain in SARS-CoV-2 Spike protein contains a receptor-binding motif RBM. SARS-CoV-2 Spike RBM is the main functional motif in RBD and allows contacts between the S protein and the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry.</p>

<p>Biotin-NY-ESO-1 (157-165) – General analog epitope of tumor cells</p>

<p>KLPGF peptide is a sequence from egg white albumen. This peptide have recently shown interest for Alzheimer’s disease.</p>

<p>MiniAP-4 peptide is a short nontoxic derivative of apamin (a neurotoxin from bee venom) used as a blood-brain barrier (BBB) shuttle peptide.</p>

GsMTx4 is a ryanodine receptor agonist that binds to the ryanodine receptor and activates signal pathways. It has been shown to activate mechanosensitive channels and regulate intracellular Ca2+ levels by inducing an increase in Ca2+ release from the endoplasmic reticulum. GsMTx4 has also been shown to have pharmacological effects on cells, as well as physiological effects on Grammostola spatulata, such as inhibition of locomotion and increased mortality. GsMTx4 has also been shown to have antiviral properties against infectious diseases such as influenza, herpes simplex virus-1, and West Nile virus.

<p>Neuropeptide:<br>Neuropeptides are small signaling molecules produced and released by neurons engaged in many physiological functions. Indeed, neuropeptides act on neural substrates such as G protein-coupled receptors (GPCRs), tyrosine-kinase receptor, insuline-like peptides and also ion channels. Actions of neuropeptides result in slow-onset, long-lasting modulation of synaptic transmission.<br>Neuropeptide NPSF (SQAFLFQPQRF-NH2):<br>Neuropeptide NPSF (SQAFLFQPQRF-NH2) is part of the FMRFamide-related peptides family. Neuropeptide NPSF has shown an important role in pain regulation and plays a role of anti-opiate. Moreover, Neuropeptide NPSF seems to be implicate in variety of physiological processes such as food intake, insulin release, blood pressure regulation and electrolyte balance. Neuropeptide NPSF (SQAFLFQPQRF-NH2) is useful in opioid research.</p>

<p>APETx2 is a drug that inhibits the activity of apetx2, a protein which is involved in the regulation of ion channels and endothelin-A receptors. APETx2 has been shown to inhibit the activity of channels involved in pain perception and may have therapeutic potential as a pressor agent. This drug has also been shown to have anti-inflammatory properties, which are likely due to its inhibition of EGF receptor activity. The mechanism of action for this drug remains unclear, but it may work by blocking the channel or receptor for EGF.</p>

<p>High quality, quantitated heavy/light peptide calibrator for actin beta in Mass Spectroscopy research. Actin beta is an actin isoform and is one of two non-muscle cytoskeletal actins. Actins play roles in cell integrity, structure and motility.</p>

<p>Lysyl-bradykinin is a potent activator of human bradykinin receptors. It is an inhibitor of protein interactions and has a high purity with CAS number 59814-34-8.</p>

<p>IL 3 Mouse is a recombinant form of human IL-3 protein with a molecular weight of approximately 30,000 Daltons. IL-3 is an important cytokine in the immune system. It has been shown to play a role in the differentiation and proliferation of T-cells and B-cells. This antibody was generated by immunizing rabbits with purified rat IL-3 protein. The antibody binds to both mouse and human IL-3 proteins with high affinity and specificity.</p>

<p>Z-Phe-Tyr is a potent irreversible inhibitor of serine proteases. It binds to the active site of the enzyme and prevents it from performing its function, which is to cleave proteins at specific sites. Z-Phe-Tyr has been shown to be effective against inflammatory bowel disease, but not against other types of diseases such as diabetes mellitus or rheumatoid arthritis. The drug inhibits protease activity and can be used in experimental models to study the molecular mechanisms of inflammation and inflammatory diseases.</p>

<p>L-asparaginase is a drug that inhibits the production of asparagine, which is an amino acid that is used in the synthesis of proteins. It has been shown to be effective against T-cell lymphomas, as well as other cancers such as leukemia and colorectal cancer. L-Asparaginase has been shown to inhibit mitochondrial functions in blood samples from patients with prostate cancer. This inhibition may lead to cell death. L-Asparaginase binds to the sephadex G-100 column in a similar manner to sodium citrate and prevents the formation of polymers when it combines with ATP. The enzyme can also be found in primary cells and liver cells, where it causes hypoglycemia by inhibiting glucose production. L-Asparaginase also inhibits dna synthesis by binding to DNA polymerases, preventing their attachment to nucleotide triphosphates (e.g., ATP).</p>

<p>The Total GLP-1-HS ELISA (1ea) is a sandwich enzyme-linked immunosorbent assay that measures the concentration of active GLP-1 in human serum. The assay employs a monoclonal antibody specific to human GLP-1 and an enzyme conjugate, which is a radiolabeled anti-human GLP-1 antibody. The Total GLP-1-HS ELISA (1ea) has been validated for use with samples from both healthy subjects and subjects with type 2 diabetes mellitus.</p>

<p>Guanylate kinase 1 is a member of the guanylate kinase family. It is a protein that in humans encoded by the GMNK1 gene. Guanylate kinases catalyze the reversible transfer of phosphate groups from ATP to guanosine diphosphate (GDP). They are involved in regulating the balance between GTP and GDP in cells, which has been shown to be important for many cellular processes, including cell signaling, cytoskeletal remodeling and apoptosis. Guanylate kinase 1 is an inhibitor of receptor tyrosine kinases, with an IC50 value of 2 μM. It also has been shown to be able to activate L-type calcium channels at concentrations greater than 100 μM. The recombinant human guanylate kinase 1 used in this study was expressed in E. coli and purified using affinity chromatography.</p>

<p>Haemagglutinin (HA) peptide YPYDVPDYA – HA Tag</p>

<p>EBV BMLF1 (280-288) is an epitope of the early lytic BMLF1 peptide of Epstein-Barr virus. EBV BMLF1 peptide presented by HLA-A*02:01 is one of the most immunogenic T-cell targets from the EBV proteome. EBV BMLF1 (280-288) can be used for the isolation and the stimulation of antigen-specific T cells.<br>Applications of EBV BMLF1 (280-288):<br>CD8+ cells have an important role in controlling Epstein-Barr virus infection. Indeed, the expansion of infected B cells is controlled by CD8+ cytotoxic T cells. Therefore, EBV BMLF1 (280-288) is important in study to detect EBV-specific CD8+ T cells by flow cytometry, per example in peripheral blood mononuclear cells of infected patients. EBV BMLF1 (280-288) is also used to analyze and measure the immune response and cytokine production in PBMCs cells to the virus with an application of ELISPOT assay.</p>

<p>Adrenomedullin 2, a peptide hormone product, of rat source and has disulfide bond between Cys10-Cys15. Adrenomedullin 2 can be applied as a potent cardiovascular and renal regulator as well as a suppressor for food intake and gastric emptying. This product is available as a 0.1mg vial.</p>

<p>Anti PACAP38 (22-38)(Human) Serum is a research tool for the study of Protein Activator of cAMP Catalytic Subunit Protein 38. It is an activator that binds to the receptor and has been shown to activate cell signaling pathways. This antibody can be used to detect PACAP38 in human serum.</p>

<p>Bis-dPEG®3-NHS Ester is a PEG polymer categorised as homobifunctional PEG (X-PEG X). Used as a linker, bis-dPEG®3-NHS Ester is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.</p>