Peptides

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of AGK antibody, catalog no. 70R-3532</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of TSTA3 antibody, catalog no. 70R-6048</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of KLHDC8B antibody, catalog no. 70R-3670</p>

<p>The MYD88 Blocking Peptide is a highly specialized product in the field of Life Sciences, Peptides, and Biochemicals. This peptide plays a crucial role in inhibiting the TGF-beta pathway, which is involved in various cellular processes such as cell growth, differentiation, and apoptosis. By blocking the activity of MYD88, this peptide effectively neutralizes the effects of TGF-beta and prevents abnormal endothelial growth.</p>

<p>Substance P is a neuropeptide that is synthesized from the precursor protein pro-opiomelanocortin (POMC). Substance P has been shown to be a potent inhibitor of the synthesis of proteins that are necessary for cell division. It also stimulates the release of inflammatory mediators and has been shown to have an activator effect on receptors. This product is used as a research tool in cell biology, biochemistry, and pharmacology.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of OSBPL8 antibody, catalog no. 70R-6725</p>

<p>Peptide H-TSALLAGTITSGWTF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of LDHA antibody, catalog no. 70R-3851</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CUTC antibody, catalog no. 70R-4342</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of EXOSC3 antibody, catalog no. 70R-4674</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of FBXL3 antibody, catalog no. 70R-2129</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of GTPBP10 antibody, catalog no. 70R-2076</p>

<p>Z-Gly-Pro-Leu-Gly is a synthetic peptide with a kinetic and biochemical profile that is similar to that of the bacterial enzyme monoiodotyrosine hydroxylase. Z-Gly-Pro-Leu-Gly has been shown to react with the substrate, monoiodotyrosine, by forming hydrogen bonds. The enzyme activities of Z-Gly-Pro-Leu-Gly are inhibited by neutral pH and increased at acidic pH. The optimum pH for this reaction is 4.5. When injected subcutaneously, Z-Gly-Pro-Leu-Gly can penetrate the skin and hydrolyze monoiodotyrosine in ascidians.</p>

<p>Anti-chromogranin A (344-374) is a peptide that binds to the receptor for gastrin. It is used as a research tool and can be used to study the pharmacology of gastrin and the role of this hormone in the regulation of stomach acid production. Anti-chromogranin A (344-374) is purified from human serum, with an antibody specific to the peptide immobilized on a solid support.</p>

<p>m-dPEG®8-Azide (Azido-m-dPEG®8) is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®8-Azide (Azido-m-dPEG®8) is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of ING3 antibody, catalog no. 70R-3052</p>

<p>Blocker of P/Q-type calcium channel (Cav2.1)</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of HINT1 antibody, catalog no. 70R-4222</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of FOXO3A antibody, catalog no. 70R-8237</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of TRIM49 antibody, catalog no. 70R-2764</p>

<p>ASIC1a/1b agonist</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PCBP4 antibody, catalog no. 70R-1627</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CHRNA5 antibody, catalog no. 70R-8064</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF570 antibody, catalog no. 70R-8409</p>

<p>Beta-Casomorphin-7 is a research tool that is used in the study of cell biology and pharmacology. It is an activator of the opioid receptor and a ligand for the receptor. The Beta-Casomorphin-7 (Bovine) antibody can be used to identify receptors on cells involved in protein interactions, ion channels, and high purity. It's CAS number is 72122-62-4.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of C22orf31 antibody, catalog no. 70R-9572</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of B3GALNT1 antibody, catalog no. 70R-6346</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of VAMP7 antibody, catalog no. 70R-8715</p>

<p>Slowing of Nav1.2, Nav1.4 and Nav1.7 channels' inactivation</p>

<p>Complement Component C5a Mouse (recombinant) is a recombinant protein that is an activator of the complement system. It can be used to investigate the role of the complement system in immune responses, inflammation, and cell death. Complement component C5a mouse (recombinant) is a potent inhibitor of ion channels and ligand-gated receptors, and has been shown to inhibit the function of voltage-gated potassium channels. Recombinant Complement component C5a mouse (recombinant) can also be used as an antibody probe for immunohistochemical detection of C5a receptor protein expression in cells. Complement component C5a mouse (recombinant) has high purity and is suitable for research purposes.</p>

<p>Thymosin β4 is a polypeptide hormone that has been studied in a variety of medical conditions. It was first discovered in the thymus gland, but is also found in other tissues, including the intestine and heart. Thymosin β4 is involved in the process of wound healing, regulating the production of collagen and fibrinogen. It also has cardioprotective effects by preventing myocyte apoptosis. There have been studies that show that thymosin β4 may be useful for treating chronic kidney disease, colorectal cancer, and polyps. The effects of this protein are mediated by its ability to regulate cellular proliferation and differentiation.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of H1F0 antibody, catalog no. 70R-2112</p>

<p>Ferredoxin-1 is a peptide that belongs to the group of activators. It can be used as an inhibitor, or as a receptor or ligand in pharmacological experiments. Ferredoxin-1 has been shown to inhibit ion channels and protein interactions. This protein may also have implications for cell biology and is used as a research tool for life science. The CAS number for ferredoxin-1 is 107899-38-2.</p>

<p>Lipid A is a bacterial endotoxin that activates macrophages and dendritic cells, which in turn activate T-cells. It is a ligand for the CD14 receptor, which is a pattern recognition molecule found on macrophages and dendritic cells. Lipid A also binds to the Toll-like receptor 4 (TLR4) on host cells, initiating an inflammatory response. Lipid A has been used as a research tool to study cell biology related to activation of macrophages and dendritic cells leading to cytokine production. This activator has also been used as a ligand in antibody studies, ion channel studies, protein interactions, pharmacology experiments with peptides, and life science research.</p>

<p>The anti G-protein: Galpha i3 (105-127) is a recombinant human serum protein. This antibody was raised against the peptide sequence of human Galpha i3 (105-127). It has been purified by Protein A and gel exclusion chromatography. The peptide sequence of this antibody is as follows: YGRKKRRQRRRPPPPPPRRRQRRKSSSSSEEEEDEESDS.</p>

<p>SPDP-dPEG®8-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. SPDP-dPEG®8-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of MCM10 antibody, catalog no. 70R-5512</p>

<p>Biotin-MAGE-A1 (278-286) is the N-ter biotinylated version of MAGE-A1 (278-286). Biotin-MAGE-A1 (278-286) can be used in the analysis of antigen-specific T cells. MAGE-A1 protein:<br>MAGE-A1 (278-286) is an epitope of Melanoma Antigen Gene A1 expressed by tumors of different histological types such as on the surface of breast carcinoma cell and is a Cancer/Testis Antigens (CTA). MAGE-A1 is a tumor antigen expressed in 40% of melanoma and contains epitope for binding HLA-A*02:01 molecules and that are recognized by cytotoxic T cells.<br>Applications of MAGE-A1 (278-286):<br>MAGE-A1 (278-286) is used to stimulate specific cytotoxic T cells in PBMCs and to analyze by ELISPOT peptide epitope specificity and cytokine production like IFN-γ. Immunogenicity of MAGE-A1 (278-286) raised the possibility of developing anticancer immunotherapies or vaccinations. MAGE-A1 is also expressed in lung adenocarcinoma and studies suggest that MAGE-A1 may serve to develop Chimeric Antigen Receptor (CAR) T cell therapy using lentiviral vector and show an encouraging tumor-inhibitory efficacy.<br>Sequence: Biotin-KVLEYVIKV</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of TRPC4AP antibody, catalog no. 70R-5845</p>

<p>α-Synuclein is a protein that is encoded by the SNCA gene, and is one of the main components of Lewy bodies, which are found in neurons in people with Parkinson's Disease. α-Synuclein has been shown to protect cells from stress and prevent their death. It also acts as a chaperone for other proteins, regulating their activity. This protein has been shown to be able to bind to GTPase activators and inhibit them from activating GTPases. The molecular weight of α-synuclein is 25 kDa and it has a pI value of 4.5. It has an acidic C-terminus and its shift on gel electrophoresis is 11.5 kDa</p>

<p>Cyclotide</p>

<p>Selective blocker of muscular nACh receptors</p>

<p>Human beta-defensin-2 (hBD-2), also known as skin-antimicrobial peptide 1 (SAP1) is a cysteine-rich cationic antimicrobial peptide of 41 amino acids. It was originally isolated from skin cells of psoriasis patients. hBD-2, which belongs to the defensin family, is implicated in the innate immunity thanks to its antimicrobial activity. Thus, β-defensins can play a role at the cutaneous level by limiting the use of antibiotics in severe burns and disease like psoriasis. Moreover, at the pulmonary level, defensins might be involved in the resorption of the infection in cases of cystic fibrosis.<br>hBD-2 is produced after stimulation of epithelial cells following their contact with some organisms like Gram-negative bacteria and Candida Albicans, fungus or cytokines such as TNF-alpha and IL-1 beta. This antimicrobial activity was shown to be microbicidal at concentrations greater than 1 µM and was lethal for E.Coli and pseudomonas (LD90 : 10 mg/mL) and Candida Albicans (LD90 : 25 mg/mL). Besides its antimicrobial activity, hBD-2 also exhibits proinflammatory properties as chemoattractants for memory T-cells, immature dendritic cells, mast cells and neutrophils.<br>hBD-2 has also demonstrated inhibitory activity of the voltage-gated potassium channel Kv1.3 at picomolar concentration. Kv1.3 are overexpressed by T-cells in case of autoimmune disorders.</p>

<p>Dihydrofolate reductase is an enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. It belongs to a family of metalloenzymes that employ NADPH as a cofactor and are involved in one-carbon metabolism. Dihydrofolate reductase has been shown to interact with a number of other proteins, including peptides, cell biology, and receptor. This enzyme is also used as an inhibitor for research purposes.</p>

<p>Anti TNF-Alpha (Rat) Monoclonal Antibody is a recombinant rat monoclonal antibody that binds to the TNF-α. It inhibits the effects of TNF-α and has been shown to protect against acute renal failure in rats. Anti TNF-Alpha (Rat) Monoclonal Antibody is a research tool for studying the function of TNF-α, and is used in pharmacological studies as an inhibitor of the enzyme protein kinase C. This antibody can be used for purification of proteins from cell culture or tissue samples.</p>

<p>Overlaping biotin-peptide library of Spike Omicron mutant. 15 amino acids per peptide with offset 11. Each peptide is N-ter biotinylated. Purity crude. 1 peptide per well.</p>

<p>Sirtuin-1 is a member of the sirtuin family of proteins, which regulate cell survival and proliferation. Sirtuin-1 regulates gene expression in response to nutrient availability by binding to DNA and modifying histones. It also functions as a homodimer that binds to various regulatory proteins and acts as a repressor or activator of transcription. This protein has been expressed recombinantly in E. Coli, where it may be used as an inhibitor of cancer cell growth. The molecular mass of this recombinant protein is approximately 94 kDa.br&gt;br&gt;<br>Sirtuin-1 is a member of the sirtuin family of proteins, which regulate cell survival and proliferation. Sirtuin-1 regulates gene expression in response to nutrient availability by binding to DNA and modifying histones. It also functions as a homodimer that binds to various regulatory proteins and acts as a repressor or activator of transcription. This protein has been expressed recombinantly in E</p>

<p>Insulin is a peptide hormone that regulates glucose levels in the blood. It is produced by beta cells in the pancreas and released when blood sugar levels rise. Insulin lowers blood sugar levels, but it also has other functions, such as protein synthesis and cell growth. Insulin stimulates receptors on cells to take up glucose from the bloodstream. Inhibitors of insulin are used for type 1 diabetes mellitus treatment and research purposes. Insulin can be used to study ion channels, antibody production, and receptor binding.</p>

<p>The IGF1 Mouse is a recombinant protein that belongs to the group of cytokines. It is produced by Escherichia coli and secreted into the culture medium. The IGF1 Mouse is used in vitro for the measurement of cytokines and cytokine receptors.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of DIDO1 antibody, catalog no. 70R-8366</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of cad antibody, catalog no. 70R-3216</p>

<p>FGF21 is a protein that in humans is encoded by the FGF21 gene. It is a member of the fibroblast growth factor (FGF) family and was originally identified as an anti-diabetic hormone that regulates glucose homeostasis. FGF21 also has roles in lipid metabolism and regulation of energy homeostasis, such as through its interactions with PPARs, RXRs, LXRs, and other nuclear receptors. The receptor for FGF21 is FGFR1c and it acts as a high-affinity agonist of this receptor. The ligand for FGFR1c is FGF19.</p>

<p>Monobiotin is a small molecule that is an activator of the L3 receptor. It has been shown to be a ligand for the L3 receptor and to activate this receptor in cells. Monobiotin activates cell membrane ion channels by binding to the L3 receptor and has been used as a research tool to study protein interactions. Monobiotin is also an inhibitor of voltage-gated potassium channels, which are important in regulating excitability in nerve cells, and can serve as a pharmacological tool for studying ion channel function.</p>

<p>TentaGel B resins represent a line of bifunctional resins that are useful for orthogonal synthesis. TentaGel; is a gelatinous resin, an important support for solid phase synthesis. TentaGel resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol) as shown below. The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix. Particle size 90 µm; capacity: 02-03 meq/g<br>Inside: NH2 Outside: Boc</p>

<p>The most potent microbicide of the mouse Paneth cell α-defensins and is degraded by MMP-7. This product has disulfide bonds between Cys4-Cys30, Cys15-Cys37, and Cys19-Cys39, is available in the Hydrochloride salt form and as a 0.1mg vial.</p>

<p>IL 4 Human, His is a recombinant protein that belongs to the class of peptides. It has been identified as an activator of IL-4 receptor and can be used in research studies to study the interactions between proteins, cells, and receptors. IL 4 Human, His can be used as an antibody to detect IL-4 in cell culture samples. IL 4 Human, His is a high purity product with a CAS Number of 57741-00-8.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of FUT6 antibody, catalog no. 70R-5379</p>

<p>TentaGel is a water-soluble polymer that can be used as a building block for various applications including drug delivery, food and beverage, cosmetics, and electronics. It consists of two main components: polyethylene glycol (PEG) and polypropylene glycol (PPG). TentaGel is soluble in water and has an average molecular weight of about 10,000 Da. The PEG-based component allows the polymer to be easily processed into particles or fibers by sonication or extrusion. TentaGel M RAM is a modified version of the original TentaGel. It contains methacrylic acid groups that have been grafted onto the PEG backbone to provide additional functionality such as reactive surfaces for conjugation with proteins or other molecules.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of TTC8 antibody, catalog no. 70R-2854</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of XAF1 antibody, catalog no. 70R-3725</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of MICAL1 antibody, catalog no. 70R-10397</p>

<p>Cystatin SN is a cysteine protease inhibitor that is involved in the regulation of protein catabolism and inflammation. Cystatins are natural inhibitors of cystein proteases, which are involved in the degradation of proteins. Cystatin-S can inhibit the activity of various cysteine proteases, including cathepsin B, cathepsin L, and papain. The recombinant human form of Cystatin SN has been shown to inhibit various ion channels such as calcium channels and potassium channels. It also inhibits the activation of other molecules by binding to them. This inhibition may be due to its ability to bind with receptors on cells or its ability to bind with ligands.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of AP1G1 antibody, catalog no. 70R-3825</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of MCM7 antibody, catalog no. 70R-1609</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of TMED8 antibody, catalog no. 70R-3834</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of KCNK10 antibody, catalog no. 70R-1533</p>

<p>D-Arginyl-[Hyp3,Thi5,D-Tic7,Oic8]-Bradykinin is a peptide that is an antagonist of bradykinin. It has been shown to bind to bradykinin receptors and inhibit the effects of bradykinin in both the vascular system and central nervous system. D-Arginyl-[Hyp3,Thi5,D-Tic7,Oic8]-Bradykinin may be used to treat diseases such as asthma or chronic obstructive pulmonary disease (COPD).</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of DENND1B antibody, catalog no. 70R-7075</p>

<p>Amyloid beta (Aβ) is a peptide fragment of the amyloid precursor protein, which is cleaved by β- and γ-secretases to form Aβ. It has been shown to be an activator of presynaptic ion channels and can bind to receptors such as the low density lipoprotein receptor related protein 1 (LRP1). Amyloid beta influences cell biology in many different ways. For example, it inhibits the growth of neurons and can induce apoptosis. In addition, this peptide can inhibit the activity of ion channels by binding to specific sites on their surface. Amyloid beta also binds to antibodies that are used for research purposes.<br>Aβ40-1 is an antibody for research purposes only.</p>

<p>IGF-1 V44M is a recombinant protein that is an activator of the insulin receptor. It has been developed as a research tool to study the function of the insulin receptor and is used in pharmacological and cell biology studies. IGF-1 V44M is a single amino acid substitution of Valine at position 44, which replaces Methionine. The recombinant protein has a molecular weight of 10 kDa, and its purity is &gt;90%. IGF-1 V44M can be used to inhibit the activity of the insulin receptor by binding to it with high affinity.</p>

<p>Biotin-SARS-CoV-2 Spike RBM 480-496 (Biotin-LC) peptide is the biotinylated version of SARS-CoV-2 Spike RBM 480-496 peptide. SARS-CoV-2 Spike RBM 480-496 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Motif (RBM). Biotin-SARS-CoV-2 Spike RBM 480-496 peptide is useful for vaccine development and for structure-activity relationship studies<br>SARS-CoV-2 Spike (S) glycoprotein<br>Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells.<br>With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane.<br>SARS-CoV-2 Spike RBM:<br>The receptor-binding domain in SARS-CoV-2 Spike protein contains a receptor-binding motif RBM. SARS-CoV-2 Spike RBM is the main functional motif in RBD and allows contacts between the S protein and the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry.</p>

<p>m-dPEG®12-Amido-dPEG®12-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®12-Amido-dPEG®12-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>FRETS-25Phe (1umol) (1umol) is a synthetic amino acid that is used as a research tool. It activates the Ligand and Receptor, which are proteins that bind to other proteins. FRETS-25Phe (1 umol) (1umol) binds to the Ion channels, which are protein structures that regulate the flow of ions across cell membranes. The activity of FRETS-25Phe (1 umol) (1umol) on Ion channels has been shown using an antibody, which is a type of protein used in immunology to identify, detect and measure antigens. FRETS-25Phe (1 umol) (1umol) also interacts with Cell Biology and Peptides, which are types of proteins involved in cell growth or division.</p>

<p>TTX-S selective blocker</p>

<p>Anti PTH (1-34) NH₂ is a peptide that inhibits the activity of parathyroid hormone. It is used to study the effects of parathyroid hormone on calcium homeostasis, and as an inhibitor in receptor binding assays. Anti PTH (1-34) NH₂ is purified from rat serum by affinity chromatography with a column containing immobilized antibodies raised against the peptide, followed by ion-exchange chromatography. The peptide has a molecular weight of 2,633.5 Da and the purity is greater than 98%.</p>

<p>Amyloid beta-Protein (Human, 1-40) (Scrambled) is a peptide that consists of 40 amino acids. It is a fragment of the amyloid precursor protein. Amyloid beta-protein has been found to have many different effects in the body, including receptor binding, ion channel activation and inhibition, and protein interactions. The peptide is also an activator for the high-affinity nicotinic acetylcholine receptor in the brain. This product can be used as a research tool or as an antibody to study amyloid beta protein in cellular biology.</p>

<p>Luteinizing hormone-releasing hormone (LHRH) is a protein that is responsible for triggering the release of luteinizing hormone (LH). LH stimulates the production and release of testosterone, which in turn stimulates sperm production. The LHRH gene encodes a protein precursor that is cleaved by proteases to produce mature LHRH. This precursor, called pro-LHRH, can be added to a protein solution to induce follicular growth in rats. Pro-LHRH has been shown to have an effect on the frequency of spermatogenesis. Proteins containing pro-LHRH can be used for hormonal research and as additives for protein solutions.</p>

<p>Fibronectin is a soluble protein that belongs to the group of linker proteins. It is found in blood plasma and extracellular fluids, where it helps to maintain the integrity of the blood vessel walls. Fibronectin also provides a scaffold for cell migration, which is especially important during wound healing. Fibronectin has been found to interact with thrombotic factors and help organize clot formation. Fibronectin also binds to collagen, which forms an insoluble network within the extracellular matrix. This insoluble network serves as a framework for cells to grow and migrate within tissues.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CCIN antibody, catalog no. 70R-2923</p>

<p>DBCO-dPEG®24-Amido-dPEG®24-DSPE is a building block that can be used in peptide synthesis. It contains a spacer arm with an amine group and a reactive end group, which can be used for attaching to other building blocks or to the amino acid side chain during peptide synthesis. The DBCO-dPEG®24-Amido-dPEG®24-DSPE is also available as part of the Quanta BioDesign Building Blocks kit, which includes seven different building blocks for use in peptide synthesis.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of SLC1A5 antibody, catalog no. 70R-1769</p>

<p>IL-1α is a cytokine that belongs to the group of proinflammatory cytokines. It plays a role in the immune response and inflammatory reactions by inducing the synthesis of other cytokines, such as IL-6, IL-8, and TNF-α. IL-1α binds to its receptor on a cell surface and activates an intracellular signalling cascade. The binding of IL-1α to its receptor induces conformational changes in the receptor, which leads to activation of phospholipase C (PLC) and production of IP3. This process results in increased levels of calcium ions inside the cell and activation of protein kinases such as PKC, MAPKs and JNKs. This results in increased activity of enzymes such as cyclooxygenase and lipoxygenase, which are responsible for inflammatory responses.</p>

<p>Protirelin – Thyrotropin-releasing hormone (TRH) (CAS: 24305-27-9)</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>SB-peptide offers the scrambled version of MAGE-A p248V9. RQYVELPYV can be used as a negative control of MAGE-A p248V9 studies.<br>SB-peptide offers also MAGE-A p248V9 (see section MAGE-A p248V9)).<br>MAGE-A protein:<br>MAGE-A p248V9, also kwon as multi-MAGE-A (YLEYRQVPV) is an epitope of Melanoma Antigen Gene expressed by tumors of different histological types and is a Cancer/Testis Antigens (CTA). Type of MAGE-A expressed in tumors cells varies according to the type of tumor. Targeting epitopes shared by all MAGE-A antigens would be interest in immunotherapy against a broad spectrum of cancers.<br>Applications of MAGE-A p248V9 (multi-MAGE-A) :<br>MAGE-A p248V9 is very useful because it could generate an HLA-A*02:01-restricted CTL response and shared by MAGE-A1,-A2,-A3,-A4,-A6,-A10 and -A12. MAGE-A p248V9 is used to stimulate specific cytotoxic T lymphocytes (CTL) in PBMCs and then to analyze CTL response especially the cytokine production by ELISPOT assay.<br>Sequence : RQYVELPYV</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Hydrogels are a class of materials that are promising candidates for use in soft tissue and bone engineering. Hydrogels have a high water content, suitable viscoelasticity and biocompatibility.<br>Using hydrogel can help for biomedical applications such as tissue engineering, encapsulation methods for cells and biomolecules, drug delivery or some injectable delivery vehicles for therapeutics.<br>However, hydrogels are mainly used for their antimicrobial properties which are due to the surface of the hydrogel, having the capacity to disrupt negatively-charged bacterial membrane via electrostatic interactions. Antimicrobial activities of hydrogels were shown against gram-positive bacteria such as S.Aureus and gram-negative bacteria like E.Coli.<br>The main interest of employing hydrogels is its biocompatibility in vitro and in vivo which permits to hydrogel to be able to perform an appropriate host response in a specific situation.<br>It also seems that the antimicrobial peptide-based hydrogels are very effective against biofilm adhesion likely due to the physical mode of action involving bacterial membrane disruption.<br>Max 1 is the first MAX peptide described, a 20-amino acid peptide designed to understand peptide intramolecular folding. Max 1 is useful for making hydrogels owing to its ability to change its structural conformation according to environmental changes.<br>Max 1 stays unfolded and soluble in a low ionic strength aqueous solution (10 mM NaCl) at neutral pH however with a high salt concentration (150 mM NaCl) or a higher pH, Max 1 folds into an amphiphilic β-hairpin conformation that can self-assembles to form a network of fibrils that conducts to the formation of a hydrogel hairpin.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>SB-peptide offers the scrambled version of MAGE-A2 (157-166). VLVYFQEIGL can be used as a negative control of MAGE-A2 (157-166) studies.<br>SB-peptide offers also MAGE-A2 (157-166) (see section MAGE-A2 (157-166)).<br>MAGE-A2 protein:<br>MAGE-A2 (157-166) is an epitope of Melanoma Antigen Gene A2 and is one of the most Cancer-Testis Antigens (CTA) overexpressed in tumors of different histological types, such as prostate cancer. Type of MAGE-A expressed in tumors cells varies according to the type of tumor. The expression of MAGE-A2 causes the proliferation of prostate cancer cells and decreases the chemosensitivity.<br>Applications of MAGE-A2 (157-166):<br>MAGE-A2 (157-166) is used to stimulate specific immune response, cytotoxic T cell response and to analyze the cytokine production in PBMCs by ELISPOT assay. In transgenic mouse, it has been demonstrated that MAGE-A2 (157-166) was capable of eliciting a CTL response presented by HLA-A*02:01 molecules. MAGE-A2 (157-166) has been reported to elicit CTL that could lyse tumor cell expressing both HLA-A*02:01 and MAGE-A2 by stimulation of peripheral blood mononuclear cells (PBMCs) with MAGE-A2 (157-166).<br>Sequence : VLVYFQEIGL</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>