Peptides

A synthetic peptide for use as a blocking control in assays to test for specificity of ATP2A2 antibody, catalog no. 70R-6108

A synthetic peptide for use as a blocking control in assays to test for specificity of NOB1 antibody, catalog no. 70R-3713

A synthetic peptide for use as a blocking control in assays to test for specificity of MEMO1 antibody, catalog no. 70R-2308

A synthetic peptide for use as a blocking control in assays to test for specificity of TM2D2 antibody, catalog no. 70R-10119

A synthetic peptide for use as a blocking control in assays to test for specificity of SOD1 antibody, catalog no. 70R-1548

A synthetic peptide for use as a blocking control in assays to test for specificity of C9orf25 antibody, catalog no. 70R-3891

A synthetic peptide for use as a blocking control in assays to test for specificity of KCNG1 antibody, catalog no. 70R-5120

A synthetic peptide for use as a blocking control in assays to test for specificity of GBP4 antibody, catalog no. 70R-1952

A synthetic peptide for use as a blocking control in assays to test for specificity of MAP3K10 antibody, catalog no. 70R-10031

A synthetic peptide for use as a blocking control in assays to test for specificity of MOS antibody, catalog no. 70R-5628

A synthetic peptide for use as a blocking control in assays to test for specificity of MORF4L1 antibody, catalog no. 70R-1284

A synthetic peptide for use as a blocking control in assays to test for specificity of A830039H10RIK antibody, catalog no. 20R-1167

A synthetic peptide for use as a blocking control in assays to test for specificity of GJC2 antibody, catalog no. 70R-6170

A synthetic peptide for use as a blocking control in assays to test for specificity of PDS5B antibody, catalog no. 70R-2864

CGRP, humanAntiserum is a peptide that is the major peptide in the calcitonin gene-related peptide family. CGRP inhibits the activation of certain ion channels, which are proteins in cell membranes that allow ions to cross the membrane. It is also known to be an activator of certain G protein-coupled receptors, as well as a ligand for some receptor types. CGRP has been shown to play a role in vascular smooth muscle contraction and pain regulation.

A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF429 antibody, catalog no. 70R-8868

A synthetic peptide for use as a blocking control in assays to test for specificity of DDHD2 antibody, catalog no. 70R-4082

A synthetic peptide for use as a blocking control in assays to test for specificity of HECTD2 antibody, catalog no. 70R-2368

HMGB1 is a protein that belongs to the family of high-mobility group box proteins. It is involved in regulating the release of inflammatory mediators and cytokines, such as IL-1β, IL-6, TNF-α and MCP-1. HMGB1 also plays a role in activation of neutrophils and macrophages. The recombinant form of HMGB1 has been shown to be an excellent research tool for studying protein interactions and receptor ligand interactions. High purity HMGB1 can be used as a pharmacological inhibitor or activator.

MonoFITC RLN2 is a peptide inhibitor of the human receptor for insulin-like growth factor 1. It has been shown to inhibit protein interactions with the insulin-like growth factor 1 receptor, which may lead to a reduction in its activation. MonoFITC RLN2 is also an activator of the G protein-coupled receptors, including adrenergic and muscarinic receptors. This peptide contains a fluorophore for easy detection.

LISA-101 is a peptide that can be used as a research tool for the study of receptor activation and ligand binding. LISA-101 is an inhibitor of ion channels, which are proteins that allow electrically charged particles to move in and out of cells. LISA-101 binds to receptors on the surface of cells and blocks ion channels from opening. This prevents the flow of ions across the membrane, which blocks nerve impulses, leading to a decrease in pain sensation. LISA-101 has been shown to inhibit voltage-gated sodium channels and calcium channels, both which are involved in pain perception.

A soluble transferrin receptor (sTfR) light tryptic peptide standard for protein identification and quantitation studies. sTfR is a cleaved extracellular segments of the transferrin receptor 1 and it can be used to measure the status of iron in the blood and thus help in studies into anemia, where iron is deficient.

Synthetic peptide toxin derivative of; M-lycotoxin from the Carolina wolf spider, Hogna carolinensis. This peptide can be used for transport into the cytoplasma and is available as a 0.5mg vial.

A synthetic peptide for use as a blocking control in assays to test for specificity of ZBTB2 antibody, catalog no. 70R-8352

Z-Gly-Phe-NH2 is a peptide that inhibits protein synthesis by binding to the ribosome. It has been shown to inhibit enzyme preparations containing peptides and proteins, such as hydrogen bond formation, phase transition temperature, uptake, and inhibitory effect. This molecule may be used in biochemical or molecular studies of protein synthesis. The uptake of Z-Gly-Phe-NH2 can be inhibited by ouabain binding. Z-Gly-Phe-NH2 also has a ca2+ response when calcium ionophores are applied to Xenopus oocytes.

Fibronectin is an extracellular matrix protein that plays a critical role in cell adhesion, migration, and differentiation. Fibronectin subunits are composed of repeating units of three types of modules: type I, type II, and type III. The active fragment of fibronectin refers to a small peptide sequence within the type III modules of fibronectin that has been shown to have potent biological activity.
The fibronectin active fragment, also known as the cell-binding domain or RGD domain, is a short peptide sequence consisting of the amino acid sequence Arg-Gly-Asp (RGD). This peptide sequence interacts with cell surface receptors known as integrins, which are important for mediating cell adhesion, migration, and signaling.
The fibronectin active fragment has been extensively studied as a research tool to investigate the mechanisms of cell adhesion and migration. It has also been used in tissue engineering applications to promote cell attachment and proliferation on synthetic biomaterials.

m-dPEG®7-Tosylate is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®7-Tosylate is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Prolactin-Releasing Peptide (Rat) is a cyclic 18-amino acid peptide that is an inhibitor of the prolactin releasing hormone. It has been shown to have a high specificity for the prolactin releasing hormone receptor and has been used as a research tool in cell biology and pharmacology. This peptide can be used to study protein interactions, which may be due to its ability to act as an activator or ligand for receptors. Prolactin-Releasing Peptide (Rat) is also able to inhibit ion channels, such as voltage-gated potassium channels and calcium channels. This peptide can also be used to generate antibodies against the prolactin releasing hormone receptor.

Bis-dPEG®7-PFP Ester is a PEG polymer categorised as homobifunctional PEG (X-PEG X). Used as a linker, bis-dPEG®7-PFP Ester is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.

Corticotropin Releasing Factor (CRF) is a peptide hormone involved in the regulation of the neuroendocrine system, the hypothalamic-pituitary-adrenal (HPA) axis. The hypothalamus releases CRF during stress and in turn CRF stimulates the production of stress hormones such as glucocorticoids and adrenocorticotropin (ACTH). A negative feedback loop is created as glucocorticoids then prevents further endocrine activity exhibited by the pituitary gland and hypothalamus. Interestingly in patients with depression, it has been found that the hypothalamic-pituitary adrenal axis is over stimulated thus increased production of CRF occurs resulting in depression symptoms. Furthermore studies have shown the expression of CRF receptors in glial cells and T-cells and elevated levels of CRF and glucocorticoids prevent T-cell proliferation. During stress cytokines can also stimulate the secretion of CRF. However CRF can also regulate these cytokines. CRF has the potential to be used in the research into depression treatments. 
This product is available as a 0.1mg vial.

Bromoacetamido-dPEG®24-Amido-DBCO is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Bromoacetamido-dPEG®24-Amido-DBCO is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Nojirimycin Bisulfite is a potent inhibitor of protein synthesis. It is a receptor-selective ligand that binds to the extracellular domain of the epidermal growth factor (EGF) receptor, thereby inhibiting receptor signaling. Nojirimycin Bisulfite has also been shown to inhibit ion channels and ligand-gated ion channels. Nojirimycin Bisulfite has been shown to bind to both peptides and antibodies, which makes it a useful research tool for studying protein interactions.

A synthetic peptide for use as a blocking control in assays to test for specificity of IFNB1 antibody, catalog no. 70R-4521

IL-1α is a cytokine protein that has been shown to be involved in the immune system. IL-1α is an activator of the receptor and is also a ligand for it. The protein has been shown to activate ion channels, which are proteins that allow ions to pass through either by diffusion or by facilitated transport. This activation causes cells to produce more hydrogen ions, which leads to an increase in the acidity of the cell. IL-1α has also been shown to inhibit cell proliferation and induce apoptosis.