Peptides

Peptide H-FSP^DDSAGASALLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Peptide H-GVASLFAGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Peptide H-EGVLYVGSK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Peptide H-LADLQVPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide Ac-Rpt-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-LEAEIATYR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-NQVVLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

SpyTag is a short peptide derived from the CnaB2 domain of the fibronectin-binding protein FbaB protein from Streptococcus pyogenes. The CnaB2 domain has a spontaneous isopeptide bond between Lys and Asp. By splitting and rational deisgn of this domain, the peptide (SpyTag) can be used in a pair to form an amide bond to its protein partner (SpyCatcher) in minutes.  This ability to self-assemble through spontaneous isopeptide bond formation works across a wide range of aqueous buffer, pH and temperatures. Thsi system is therfore a valuable conjugation tool for biotechnolgy and bioengineering.Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesinB. Zakeri, J.O. Fierer, E. Celik, E.C. Chittock, U. Schwarz-Linek, V.T. Moy, M. Howarth, Proc. Natl. Acad. Sci. U.S.A.109 (12) E690-E697 Catalyst-free thiazolidine formation chemistry enables the facile construction of peptide/protein-cell conjugates (PCCs) at physiological pH X Liu, Y Wang, B Ye, X Bi - Chemical Science, 2023 - pubs.rsc.orghttps://pubs.rsc.org/en/content/articlehtml/2023/sc/d3sc01382k AlbuCatcher for Long-Acting Therapeutics JH Rho, JH Lee, I Kwon - ACS omega, 2024 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acsomega.4c02303 T Cell Activating Thermostable Self-Assembly Nanoscaffold Tailored for Cellular Immunity Antigen Delivery J Zhang, J Yang, Q Li, R Peng, S Fan, H Yi - Advanced , 2023 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/advs.202303049

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-SIISMFDR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-Met-Asp-OH is a synthetic formyl peptide that was designed to be hydrolyzed by proteolytic enzymes. It has been shown to be able to inhibit the formation of β-amyloid, which is associated with Alzheimer's disease. H-Met-Asp-OH also has been shown to have physicochemical properties similar to aspirin, and can be used as an antiplatelet agent. In addition, it has been shown to act as a catalase inhibitor in vitro and may have some therapeutic potential for the treatment of diabetes mellitus type 2.</p>

<p>pE-HWSY(dW)L^RP-NHEt is a catalog research peptide that is held in stock. pE-HWSY(dW)L^RP-NHEt is provided at &gt;85% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer pE-HWSY(dW)L^RP-NHEt in bulk quantities in addition to our standard pack sizes.Please enquire for more information about pE-HWSY(dW)L^RP-NHEt at the technical inquiry form on this page</p>

<p>Cyclo(-Pro-Val) is a type of natural product that has been shown to inhibit the growth of tumor cells. Cyclo(-Pro-Val) is a metabolite produced by the fungus Cryptococcus neoformans and may serve as a potential anti-cancer drug. The compound blocks mitochondrial membrane potential, which prevents cancer cells from multiplying. Cyclo(-Pro-Val) has also been shown to inhibit the growth of bacteria such as Pseudomonas aeruginosa and Burkholderia cepacia complex, although it has little or no effect on other types of bacteria and fungi.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>H-Tyr-Arg-Leu-Leu-Ser-Phe-NH2 is a peptide that is used as a research tool for studying the role of PAR receptors in the regulation of vascular tone. It also has been shown to have an effect on blood pressure, which may be due to its ability to activate PAR2 receptors.</p>

<p>Tertiapin Q is a peptide inhibitor, a derivative of tertiapin, from honeybee venom (specifically Apis mellifera). This peptide acts by specifically blocking certain potassium channels, namely Kir1.1 and Kir3.1/3.4. The mode of action involves binding to the outer mouth of the potassium channel pore, effectively inhibiting ion flow through these channels. Tertiapin Q varies from native tertiapin by one amino acid, where a methionine residue is replaced with a glutamine residue. This means that unlike native TPN, TPN(Q) is not air oxidizable.Tertiapin    : H-Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Met-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2Tertiapin Q: H-Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Gln-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2Tertiapin Q is used in electrophysiological research to study the role and regulation of inward-rectifier potassium channels in various physiological and pathological processes. Its specificity and potency make it an invaluable tool in the exploration of renal physiology and cardiac cellular activity, as well as in neuroscience research for understanding neuronal excitability.</p>

<p>Please enquire for more information about rec IL-1alpha (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Thr-AMC is a small molecule that binds to the ubiquitin-proteasome system and inhibits the degradation of proteins. It has been shown to inhibit methionine aminopeptidase, which is an enzyme that degrades amino acids in the intestine. H-Thr-AMC also has a metal chelator effect, which prevents it from being degraded by proteases. The sequence of H-Thr-AMC was derived by sequencing cDNA from eukaryotes. H-Thr-AMC is not active against aminopeptidase A, but can inhibit aminopeptidase B and C. H-Thr-AMC has been shown to have inhibitory effects on both intestinal and physiological properties.br&gt;br&gt;<br>H-Thr-AMC is a substrate for the peptide:hydrolase (peptidase) family of enzymes known as aminopeptid</p>

<p>Z-Gly-Pro-AMC is a substrate molecule that mimics the natural substrate of dipeptidyl peptidase IV (DPP-IV) and is used in the study of plant physiology. It has been shown to inhibit DPP-IV activity by binding to the enzyme’s active site, preventing it from cleaving biologically active peptides. This drug also has an antidiabetic effect, which may be due to its ability to inhibit α-amylase activity. Z-Gly-Pro-AMC also has been shown to increase locomotor activity and reduce body weight in rats with metabolic disorders. Z-Gly-Pro-AMC inhibits serine proteases, such as trypsin, chymotrypsin, elastase, and cathepsin G, which are involved in tumor progression.</p>

<p>Ac-Lys-pNA hydrochloride is a protease that belongs to the endopeptidase class of proteolytic enzymes. It is used in research and recombinant expression to cleave proteins at specific sites. Ac-Lys-pNA hydrochloride is activated by ammonium sulfate, which binds to the active site of the enzyme. The enzyme also cleaves peptides with Lys or Arg at the C terminus. Ac-Lys-pNA hydrochloride has been shown to be effective against aeruginosa, but not escherichia coli, which are both gram negative bacteria.</p>

Ac-Ala-Ser-Thr-Asp-AMC is a versatile building block that can be used as an intermediate in organic synthesis, a reagent, or a speciality chemical. It is also a useful scaffold for drug discovery and development. Ac-Ala-Ser-Thr-Asp-AMC has been shown to be an effective inhibitor of phosphodiesterase 3 (PDE3) and cyclic nucleotide phosphodiesterases (PDEs).

<p>Peptide H-LGFEDGSVLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-Glu-Thr-OH is a molecule that belongs to the group of aminoglycosides. It is a broad spectrum antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. H-Glu-Thr-OH has been shown to be effective against various bacteria, including those that are resistant to other antibiotics such as penicillin and erythromycin. This drug has also been shown to be effective against cancer cells in vitro. H-Glu-Thr-OH is a potent inhibitor of inflammatory bowel disease, which may be due to its ability to inhibit the production of proinflammatory cytokines such as tumor necrosis factor alpha (TNFα). The drug also has an insulin sensitizing effect in type 2 diabetes mellitus patients, which may be due to its ability to enhance glucose uptake into skeletal muscle cells and adipocytes.</p>

The E22delta (Osaka mutation) mutation of Amyloid β promotes β-sheet transformation.

<p>Fluorescent substrate for angiotensin-converting enzyme 2</p>

This resin is for use in combinatorial chemistry. TentaGel is a gelatinous resin and an important support for solid phase synthesis. TentaGel resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol) as shown below. The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix. Particle size 130 µm; capacity: 0.2-0.35 meq/g Substitution Functional Group: -O-CH2-CH2-NH2

<p>H-Lys-D-Trp-Phe-D-Trp-Leu-Leu-NH2 is a potent full inverse agonist for the Ghrelin Receptor. Ghrelin is a peptide hormone that stimulates GH release from the anterior pituitary gland. Ghrelin also has other functions in the body. It binds to the ghrelin receptor and increases appetite and gastric motility. Ghrelin can also stimulate insulin secretion from pancreatic beta cells. Ghrelin levels are high before meals and decrease after eating.</p>

A synthetic snake toxin peptide sourced from Green Mamba, Dendroaspis angusticeps. This product is a specific ligand for Muscarinic Acetylcholine Receptor-1 (M1), has disulfide bonds between Cys3-Cys24, Cys17-Cys42, Cys46-Cys57, and Cys58-Cys63 and is available as a 0.1mg vial.

Please enquire for more information about AF488 Maleimide including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>H-Gly-Arg-Gly-Asp-Ser-Pro-Cys-OH is a monoclonal antibody (mAb) that binds to the cell surface receptor, TGFβRI. It has been shown to exhibit biological activities including inhibition of tumor growth and induction of apoptosis in cancer cells. This mAb can be used as a tumor treatment and can also inhibit the proliferation of cells in tissue culture. H-Gly-Arg-Gly-Asp-Ser-Pro-Cys has been shown to inhibit the production of collagen, which may be due to its ability to block integrin activation by binding to the cell surface receptor, αVβ3. HGRGSSPC has also been found to have antiangiogenic properties, which may be due to its ability to bind with high affinity and specificity to αVβ3 on endothelial cells.</p>

Please enquire for more information about rec IL-2 (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Cyclo(Arg-Ala-Asp-D-Tyr-Lys) is a peptide macrocycle that has been shown to have potent anti-cancer activity. It binds to the receptor for epidermal growth factor (EGF), which is overexpressed in many cancers, and inhibits its function. Cyclo(Arg-Ala-Asp-D-Tyr-Lys) is also able to inhibit the production of nitric oxide by inhibiting the synthesis of arginase. This peptide has also been shown to induce apoptosis in cancer cells by altering the mitochondrial membrane potential and activating caspases 3 and 9.</p>

2-Chlorotrityl Chloride Resin (200-400 mesh) 1% DVB is a resin that is used as a building block for peptide synthesis. It can be used to synthesize the building blocks for peptides, including amino acids, alcohols and amines. 2-Chlorotrityl Chloride Resin (200-400 mesh) 1% DVB has been shown to react with thiols, alcohols and amines in solution to form covalent bonds. It can also be used as a tool in the synthesis of thiols, alcohols or amines.

<p>Ac-Tyr-Val-Nle-Gly-His-D-Phe-Arg-Trp-Asp-Arg-Phe-Gly-NH2 is a peptide that is a melanocortin receptor agonist. It has been shown to have biochemically active properties and can be used as a research tool in the study of peptides and their receptors.</p>

Peptide H-NDPTQQIPK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Head activator Pyr-Pro-Pro-Gly-Gly-Ser-Lys-Val-Ile-Leu-Phe-OH is a synthetic peptide, which is modeled after bioactive peptides found in certain biological systems. It is derived from the head activator peptides naturally occurring in organisms like hydra and is believed to play a role in neurochemical signaling pathways.The mode of action of this peptide involves the modulation of neuronal activity and proliferation through specific interactions with cellular receptors, influencing processes such as cell growth and differentiation. These interactions may contribute to neuroprotection and support neural regeneration, making it a subject of interest in neurobiological research.Given its role in cellular signaling, Head activator Pyr-Pro-Pro-Gly-Gly-Ser-Lys-Val-Ile-Leu-Phe-OH is primarily used in research contexts, especially in studies focusing on neurobiology, regenerative medicine, and the molecular mechanisms underlying neural development. Its ability to mimic certain endogenous signaling processes allows scientists to explore the regulation of neural cell behavior and the potential therapeutic applications for neurodegenerative conditions.</p>

<p>CRF (human, rat) acetate is a synthetic chemical that has been shown to produce long-term changes in the brain. It is chemically similar to CRF, which is an endogenous hormone produced by the hypothalamus. This drug is used for the treatment of cerebral edema and intracranial hypertension caused by various conditions, such as cancer. The effects of CRF (human, rat) acetate on humans are not well understood as this drug has only been tested in women who have undergone surgery to remove their ovaries. These women had increased levels of corticotropin-releasing hormone (CRH), which could be due to CRF (human, rat) acetate or its metabolites. There is also some evidence that it may cause corrosion in long-term use.</p>

<p>Z-Tyr-Ser-OH is a fine chemical that is used as a versatile building block in the synthesis of complex compounds. It is also a useful intermediate for the production of many other chemicals, including pharmaceuticals, agrochemicals and research chemicals. The CAS number for Z-Tyr-Ser-OH is 20448-71-9. This compound has been shown to be a high quality reagent with many applications in research and commercial manufacturing.</p>

<p>Please enquire for more information about rec IL-10 (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Cyclo(-Leu-Trp) is a sweetener that has been used in the food industry for many years. Cyclo(-Leu-Trp) is able to bind with quinine and form a complex that can be detected using analytical methods. Cyclo(-Leu-Trp) has been investigated as a ligand that may be able to bind to receptors on cancer cells, which could lead to new treatments for cancer. Cyclo(-Leu-Trp) also has amphipathic properties and can form liposomes at high concentrations. This molecule has also been studied for its ability to induce transduction of DNA into bacterial cells and cellular thermogenesis.

<p>Abz-Phe-Arg-Lys(Dnp)-Pro-OH trifluoroacetate (ABA) is a low potency activator of the endogenous angiotensin system, with no known clinical use. ABA has been shown to activate the endogenous angiotensin system in vivo in rats and humans. It has also been shown to increase blood pressure in rats by activating the renal sympathetic nervous system. The activation of this system may be due to its ability to release neutrophil chemotactic factor from adipose tissue, increasing the number of neutrophils that contribute to inflammation through their release of reactive oxygen species. The mechanism underlying this activation is unknown, but may involve an interaction with enalaprilat, a potent inhibitor of angiotensin converting enzyme (ACE), or adipose tissue lipolysis.</p>

<p>Please enquire for more information about Peptide M trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

H-Gly-Pro-pNA is an antidiabetic drug that inhibits the activity of dipeptidyl peptidase IV (DPP IV), a family of enzymes that catalyses the cleavage of the amino acid sequence of proline and arginine. The inhibitory effect on DPP IV by H-Gly-Pro-pNA was demonstrated using magnetic resonance spectroscopy, chromatographic assays, and electrospray ionization mass spectrometry. H-Gly-Pro-pNA also has hydrophobic properties and can interact with other drugs that are lipophilic. In vitro assays have been used to determine the inhibition activity of H-Gly-Pro-pNA against various proteins involved in diabetes mellitus, including aminopeptidases, carboxypeptidases and endopeptidases.

<p>H-Glu-Val-OH is a coordination complex that contains the metal scandium. It is used as a ligand to form complexes with other metals and organic molecules. This compound is also used in peptide synthesis and has been shown to have a strong interaction with nitrate, serine, and formiate. H-Glu-Val-OH is soluble in solutions such as water or formiate. The tripeptide Ser-Gly-Val can be formed from this compound by hydrolysis of the hydroxo group.</p>

Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate is a cyclic peptide that has been shown to be an effective chemotherapeutic agent against bladder cancer. Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate binds to the integrin receptor on the tumor cell surface and blocks the formation of new blood vessels, which may lead to tumor growth inhibition. The hypoxic tumor environment is characterized by low oxygen levels, which causes the mitochondria in cells to produce more hydrogen peroxide. Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate has been shown to decrease the production of hydrogen peroxide in hypoxic tumors. This drug also inhibits angiogenesis and cellular proliferation. Cyclo(-Arg-Gly-Asp) trifluoroacetate has

<p>Apelin-17 trifluoroacetate is a reaction component, reagent and useful scaffold for the synthesis of complex compounds. It is a high quality, research chemical that is used in the synthesis of fine chemicals. Apelin-17 trifluoroacetate has versatile building block and can be used as a useful intermediate or as a speciality chemical. It also has high reactivity and is soluble in organic solvents.</p>

<p>H-Lys-Pro-AMC hydrochloride is a fine chemical that is a versatile building block, useful intermediate, and speciality chemical. It can be used as a reaction component or in research or production of other chemicals. H-Lys-Pro-AMC hydrochloride can be used to make high quality reagents for use in research and production of other chemicals. This compound has been shown to be useful as a scaffold for the synthesis of complex compounds.</p>

<p>L-Seryl-L-tyrosine 7-amido-4-methylcoumarin is a fine chemical that is used as a versatile building block in the synthesis of more complex compounds. It is a reagent and speciality chemical that can be used in research, detection, and analytical chemistry. L-Seryl-L-tyrosine 7-amido-4-methylcoumarin has been shown to be an excellent reaction component with high quality and purity. This product can also be used as a scaffold for the preparation of new compounds with desired properties.</p>

A synthetic sea anemone toxin peptide, that can be applied as a voltage dependent K+ channel (A Channel) blocker.

<p>Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist that is used to treat type 2 diabetes. Lixisenatide has been shown to be safe and effective in patients with renal impairment, hepatic impairment, or congestive heart failure. The pharmacokinetics of lixisenatide have been studied in healthy subjects and patients with chronic renal failure receiving dialysis. Lixisenatide has been shown to have a linear pharmacokinetic profile in both populations and has not been found to accumulate in the plasma after repeated doses. Lixisenatide does not bind tightly to human serum albumin, which may make it more suitable for use in patients with atherosclerotic cardiovascular disease who exhibit hyperlipidemia because it will be less likely to affect lipid profiles.</p>