Peptides

<p>H-Arg-Gly-Asp-Cys-OH is a biomimetic amino acid that possesses the same three-dimensional structure as the amino acid sequence found in the human epidermal growth factor receptor 2 (HER2). This compound has been shown to inhibit the activity of enzymes, such as kinases, which are involved in cancer cell division. It also can be used to target and destroy cancer cells using gene therapy. H-Arg-Gly-Asp-Cys-OH binds to messenger RNA and inhibits its translation into protein, which may lead to cell death. H-Arg-Gly-Asp-Cys -OH has been shown to bind specifically with HER2 receptors on breast cancer cells and promote their destruction by inducing apoptosis.</p>

Please enquire for more information about 6-FAM-AEEAc-Stichodactyla helianthus neurotoxin (ShK) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

Gurmarin is a polycyclic diterpene that can be found in the bark of the G. lucidum tree. It has been shown to bind to glutamate receptors, which are ion channels that allow ions such as calcium and sodium to pass through cell membranes. Gurmarin has been shown to activate these receptors in vitro, and knockout or over-expression of these receptors in cells can lead to changes in receptor activity. Gurmarin has also been shown to have specific binding affinity for a certain type of receptor cell, which are cells with cation channels that may be involved in taste perception. The receptor binding site on the gurmarin molecule is thought to correspond with the sweet taste sensation.

<p>Glutathione Disulfide (GSSG) Methyl Ester is a reactive molecule that is formed by the oxidation of glutathione. It is used in studies on oxidative stress and its role in tumorigenesis. GSSG Methyl Ester has been shown to bind to DNA and inhibit transcription. GSSG Methyl Ester is also used as a fluorescent probe for measuring intracellular glutathione levels. This compound has also been shown to have antioxidant properties, which may be due to its ability to scavenge reactive oxygen species and reduce cellular damage.</p>

CATH-2 is a monoclonal antibody that inhibits the enterotoxin activity of E. coli, which is mediated by several strains of the bacteria. CATH-2 has been shown to be effective against enteritidis, an E. coli strain that causes food poisoning. It is not active against other strains of E. coli or Salmonella species and does not have any antibiotic effects. CATH-2 also has immunomodulatory effects and boosts chemokines such as MCP-3 and IL-8, which are chemokine receptors expressed in intestinal epithelial cells that may contribute to its anti-inflammatory properties.

Atorvastatin acid is a pharmaceutical compound belonging to the class of statins, which is a synthetic derivative of fungal metabolites. It functions as an HMG-CoA reductase inhibitor, playing a critical role in the cholesterol biosynthesis pathway. By inhibiting this key enzyme, atorvastatin acid effectively reduces the conversion of HMG-CoA to mevalonate, a precursor of cholesterol, thus lowering overall cholesterol levels in the bloodstream.

<p>Peptide H-DCL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-Pro-Ile-OH is an amino acid that is found in the mitochondria of cells. It is a prodrug that binds to angiotensin and blocks its conversion to angiotensin II, which has been shown to have blood pressure lowering effects. H-Pro-Ile-OH has been shown to be a competitive inhibitor of oligopeptidase, with a half maximal inhibitory concentration (IC50) of 0.5 mM, and has also been shown to have antihypertensive properties.</p>

<p>Please enquire for more information about rec IL-2 (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Ac-Asp-pNA is a carboxy, serine protease that is used as an antigen in bactericidal and antibacterial assays. It also has been shown to be effective against neutral ph organisms such as E. coli and Pseudomonas aeruginosa. Ac-Asp-pNA elutes from the column when it is inactivated under neutral ph conditions, which can be seen by the presence of reactive peaks. The protonation of Ac-Asp-pNA at high pH results in a loss of reactivity, which can be detected by the diminazene peak at low pH. This protein is activated by potassium ions and cellular proteins, which can be seen by the presence of peaks at m/z 816 and 806 respectively.

This synthetic peptide is a hydrophobic RGD Fibronectin Peptide which enhances cell attachment and adhesion. This is due to it containing the Arg-Gly-Asp (RGD) sequence, is a highly conserved integrin recognition sequence within fibronectin. As a result it can promote the adhesion of cells to fibronectin, a protein found in the extracellular matrix and also promotes adhesin of cells to collagen and laminin. One-Letter Formula: Ac-GrGDSPASSKGGGGSrLLLLLLr-Amide

<p>Cys- Modified HIV TAT Sequence 49-57, a derivatizable cell-penetrating peptide (CPP) for click chemistry. Product available as a Trifluoroacetate Salt</p>

<p>Please enquire for more information about Angiotensin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Suc-Gly-Pro-Leu-Gly-Pro-AMC (SGLP) is a synthetic substrate that is hydrolyzed by proteases and has been used as a model substrate in protease studies. It has been shown to be cleaved by a number of enzymes, including chymotrypsin, trypsin, elastase, and cathepsin D. The hydrolysis products are sucrose glycolate, glycerol phosphate, leucine amino acid ester, and proline amino acid ester. SGLP has been shown to have low bioavailability in human liver cells and heart tissue. Studies have also shown that SGLP can stimulate the production of myelocytic cells in vitro. This activity may be due to its ability to act as an immunomodulator or by targeting tissue enzyme activities.</p>

IsoDTB (Isotopically labeled Desthoibiotin Azide) probes take advantage of the mass shift of stable heavy isotope labels (SHLs) to enable mass-independent chemical proteomics platform that helps to address unique challenges of the proteome characterization. In this approach a unique isotopic signature is embedded exclusively into the peptides and it serves as a computationally recognizable full-scan MS reporter. By using desthiobiotin, these probes circumvented the need to use cleavable linkers for peptide elution and thus simplifies the chemoproteomic protocol, while allowing quantification of the proteome. IsoTDB pack contains 2 mg of light (IsoDTB-L) and heave (IsoDTB) probe.

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

H-Pro-Arg-OH acetate salt is a synthetic, antioxidative molecule that has been shown to lower blood pressure in animals. It is also an effective inhibitor of the oxidation of diploid cells and has been shown to be safe for long-term use. H-Pro-Arg-OH acetate salt is used as a structural probe for studies on the binding of fibrinogen to plasminogen. This compound has also been shown to reduce protamine's ability to inhibit fibrinolysis, which may lead to improved blood clotting times.

<p>Peptide H-EIMAEIYK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is an activator that has been shown to be able to inhibit ion channels. This peptide can also be used as a research tool for studying protein interactions, receptors, and ligands.

<p>H-Trp-Trp-Trp-OH is a protonated tripeptide that has hydrophobic properties. It is highly soluble in water, but not in organic solvents. The protonation of the amino acid residues in H-Trp-Trp-Trp-OH has been shown to be pH dependent. This compound is synthesized by reacting an amino acid with a carboxylic acid, which gives the product a bitter taste. The synthesis of this compound also yields reaction products that are acidic and exhibit anti tumor effects. This product can be used as a prebiotic to promote the growth of beneficial bacteria in the gastrointestinal tract.</p>

<p>Abz-Phe-Arg-Lys(Dnp)-Pro-OH trifluoroacetate (ABA) is a low potency activator of the endogenous angiotensin system, with no known clinical use. ABA has been shown to activate the endogenous angiotensin system in vivo in rats and humans. It has also been shown to increase blood pressure in rats by activating the renal sympathetic nervous system. The activation of this system may be due to its ability to release neutrophil chemotactic factor from adipose tissue, increasing the number of neutrophils that contribute to inflammation through their release of reactive oxygen species. The mechanism underlying this activation is unknown, but may involve an interaction with enalaprilat, a potent inhibitor of angiotensin converting enzyme (ACE), or adipose tissue lipolysis.</p>

3-O-Hexadecyl-sn glycerol (3OHG) is a neutral, high molecular weight glycol ether that is used for the preparation of zirconium oxide. 3OHG has been shown to be a substrate for carbohydrate chemistry and as an inhibitor of enzymes, such as hexokinase and phosphoglycerate kinase. 3OHG has minimal toxicity when administered orally to rats and does not cause any hemolysis in human erythrocytes. This compound is also a monoclonal antibody that binds to the surface glycoprotein on the HL-60 cell line and inhibits its growth. 3OHG is not cytotoxic at concentrations up to 10 mM in cultured cells, but it can induce Ca2+ release from the cytosol in HL-60 cells with minimal toxicity. The structure of 3OHG appears closely related to benzalkonium chloride (BAC).

Hippuryl-arginine is a peptide hormone that is released by the hypothalamus and stimulates the pituitary gland to release other hormones. It has been shown to increase chemotactic activity in human serum, although it has no effect on carboxypeptidase or soybean trypsin activity. Hippuryl-arginine binds with basic proteins, such as albumin and immunoglobulins, and increases their enzymatic activities. This hormone also inhibits enzymes such as carboxy terminal phosphatases and aminopeptidases that are responsible for degrading amino acids. Activation of hippuryl-arginine may be due to its carboxy terminal group, which is susceptible to cleavage by proteolytic enzymes.

<p>This substrate contains the nsp4/nsp5 cleavage sequence, GVLQ↓SG19, and works as a generic peptide substrate for several coronavirus. The main protease (Mpro­), also called endopeptidase C30 or 3C-like proteinase (3CLpro), controls viral replication activities, and is a prime therapeutical target. It also contains SARS-CoV2 Replicase pp1ab (3235-3246). It can be used as a Fluorogenic Substrate for SARS-CoV/SARS-CoV-2 Main Protease (Mpro) and is avaiable in as a Trifluoroacetate Salt.</p>

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

<p>Modified HIV TAT Sequence 49-57 for Click Chemistry. Product available as a trifluoroacetate salt</p>

<p>Peptide H-SVDQRGNQ-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Hepcidin, also known as LEAP-1 (liver-expressed antimicrobial peptide) or Hepcidin-25 is a hormone of 25 amino acids. Hepcidin is a cationic, cysteine-rich and tightly folded peptide stabilized by 4 disulfide bonds that plays a major role in innate immunity and iron homeostasis. Hepcidin inhibits iron transport by binding to the iron export channel ferroportin which is located on the basolateral surface of gut enterocytes and the plasma membrane of reticuloendothelial cells (macrophages). Hepcidin breaks down the transporter protein in the lysosome. Inhibiting ferroportin prevents iron exportation and iron is retained in cells. Hepcidin is regulated by iron through a complex of integral hemochromatosis proteins, like HFE, HJV and transferrin receptor 2. Hepcidin is also characterized by is antimicrobial activity in several vertebrate species, exerting its antimicrobial effect against both Gram-positive and Gram-negative bacteria as well as yeast, with for example an IC50 value against Saccharomyces cerevisae of 18 µM.

Peptide Fmoc-AACK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>H-Lys-Pro-AMC hydrochloride is a fine chemical that is a versatile building block, useful intermediate, and speciality chemical. It can be used as a reaction component or in research or production of other chemicals. H-Lys-Pro-AMC hydrochloride can be used to make high quality reagents for use in research and production of other chemicals. This compound has been shown to be useful as a scaffold for the synthesis of complex compounds.</p>

<p>H-Ala-Phe-Lys-AMC trifluoroacetate salt is a chemical compound that can be used as an intermediate in the synthesis of peptides, peptidomimetics, and other organic compounds. This reagent is a high quality, versatile building block that can be used in the synthesis of complex compounds. H-Ala-Phe-Lys-AMC trifluoroacetate salt is a fine chemical that has been assigned CAS No. 120928-02-1. It is a useful scaffold for the synthesis of novel compounds with potential pharmaceutical value.</p>

<p>Mca-Ala-Pro-Lys(Dnp)-OH trifluoroacetate salt is a high quality, versatile, and speciality chemical that is used as an intermediate in the synthesis of complex compounds. Mca-Ala-Pro-Lys(Dnp)-OH trifluoroacetate salt is also a useful scaffold for building block molecules and a versatile building block for peptide synthesis. This compound can be utilized in the manufacture of research chemicals and speciality chemicals.</p>

<p>H-D-Glu(Gly-OH)-OH is a peptide that is used to study the mechanism of glutamate receptors. It has been shown to have an excitatory effect on mouse hippocampal and cerebellar purkinje neurons, with affinity values for membrane channels. It also has been shown to reduce gamma-aminobutyric acid (GABA) levels in the hippocampus and striatum, which may be due to its ability to inhibit glutamic acid decarboxylase. H-D-Glu(Gly-OH)-OH is a potent antagonist of glutamate, binding competitively at the glutamate site on ionotropic receptors. It also inhibits acidic pH and calcium ion concentrations, which are necessary for ionotropic receptor activation.</p>

<p>Peptide Cyc-Ruth-AGCKNFFWKTFTSC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Z-Arg-Leu-Arg-Gly-Gly-AMC acetate is a protease inhibitor that blocks the activity of the proteasome. It has been shown to inhibit the activity of histidine proteases and to inhibit proteolysis by the proteasome in a kinetic assay. This inhibitor also inhibits coronavirus replication, which may be due to its ability to bind to histidine residues on proteins involved in viral replication. Z-Arg-Leu-Arg-Gly-Gly-AMC acetate is expressed in transfected cells as an enzyme with a polymerase chain reaction (PCR) product and has been shown to prevent viral replication.</p>

Fmoc-Glu(OtBu)-Rink-Amide MBHA Resin is a high purity, ion channel ligand that is used in research as a pharmacological tool. It is an activator of Kv1.3 channels and inhibits the function of Kv1.2 channels. This product can be used for the study of protein interactions and receptor pharmacology. Fmoc-Glu(OtBu)-Rink-Amide MBHA Resin also has been found to inhibit the binding of antibodies to cells and can be used for immunoprecipitation experiments. This product has CAS number 188476-46-4 and is available in 1 g and 5 g sizes.

A synthetic sea anemone toxin peptide, that can be applied as a voltage dependent K+ channel (A Channel) blocker.

HsTX1 is a peptide toxin obtained from the venom of the scorpion Heterometrus spinnifer. It blocks potassium channels and inhibits the activity of Kv1.3 channels, which are responsible for neuronal repolarization and firing. This peptide is also a blocker of voltage-gated sodium channels, but has no effect on calcium channels. HsTX1 is used in medical research as a tool to study ion channel function.

Fmoc-Tyr(tBu)-Rink-Amide MBHA Resin is a solid phase peptide synthesis resin that is used for the production of small scale peptides. This resin has high purity and can be used in the synthesis of proteins, antibodies, and other bioactive molecules. Fmoc-Tyr(tBu)-Rink-Amide MBHA Resin is an ion-exchange resin that can be used to purify peptides by binding to their charged side chains. It is also useful as a research tool for cell biology, receptor pharmacology, and as an inhibitor.

<p>Peptide H-CYPYDVPDYASLRSL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide EKSQDGGR is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-GTCACTC-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-SAPHGVVFL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>KRASᴳ¹²ᴰ peptide is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-FLHVTYVPAQEKNFT-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-GVLTESNKK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-PGPSDTPILPQ-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-FADLSEAANR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Fibrin knob B mimic peptide is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>