Peptides

Custom research peptide; min purity 95%.

CCK-Octapeptide (26-33) is a peptide that is a member of the cholecystokinin family of peptides. CCK-Octapeptide (26-33) is an activator of the CCK receptor and can be used for research purposes. This peptide has been shown to inhibit ion channels, which are proteins that regulate the flow of ions across cell membranes, and may be used as a pharmacological tool or research tool.

Bis-dPEG®7-NHS Ester is a PEG polymer categorised as homobifunctional PEG (X-PEG X). Used as a linker, bis-dPEG®7-NHS Ester is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.

GH Bovine is a peptide hormone that stimulates the production of IGF-1, which is an important regulator of growth and metabolism. GH Bovine binds to the GH receptor, a G protein-coupled receptor, and triggers its activation. It also interacts with other receptors, such as the insulin receptor. GH Bovine is a research tool for studying the interactions between proteins. GH Bovine has been used in pharmacology to study the role of GH in humans, including its effects on cancer cells. GH Bovine has been shown to have an inhibitory effect on cell proliferation and DNA synthesis in vitro. This product is highly purified and has a CAS number of 714-69-2.

Arphamenine B is a potent, selective, and reversible inhibitor of the protein tyrosine phosphatase 1B (PTP1B). Arphamenine B binds to PTP1B with high affinity and specificity. It is a useful tool for studying protein-protein interactions and protein function. Arphamenine B can also be used as an activator or ligand for receptors, especially G-protein coupled receptors. This peptide has been shown to inhibit ion channels such as calcium channels, potassium channels, and sodium channels.

HBB MS Calibrator is a research tool that is used to calibrate mass spectrometry. It is an activator of Ligand and Receptor, which are proteins that play a role in cell biology. HBB MS Calibrator binds to ion channels and inhibits the opening of these channels. This leads to a decrease in the flow of ions through the channel, which can affect a number of cellular processes. HBB MS Calibrator also has pharmacological properties that are used for drug discovery and peptide production.

Leptin is a protein hormone that is produced by fat cells. Leptin regulates appetite and energy use, and it has been shown to be involved in the regulation of body weight. Leptin binds to receptors on the surface of cells, which activates signaling pathways inside the cell. This receptor can be activated by other ligands such as ghrelin, adiponectin, and insulin. Leptin also inhibits ion channels in neurons, resulting in an increase in potassium conductance.

Lys-Ala-AMC is an activator of ion channels and a ligand for receptors. It is used in research as a tool to study protein interactions, receptor pharmacology, and ion channel pharmacology. Lys-Ala-AMC binds to the α-subunit of voltage gated calcium channels and can activate these channels by increasing the rate of opening. This peptide also inhibits receptor binding by competing with the natural ligand. It has been shown to be an antagonist at the NMDA receptor and can inhibit the binding of glycine to this receptor.

MAL-dPEG®24-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. MAL-dPEG®24-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

IL 4R is a receptor for Interleukin-4. It is a member of the type II cytokine receptor family and has been shown to be an inhibitor of cell proliferation. IL 4R also interacts with the protein tyrosine phosphatase SHP2, which plays a role in signaling pathways. IL 4R binds to specific Ligands, such as IL-4 and IL-13, that are found in the extracellular matrix and on the surface of cells. These interactions activate the receptor and lead to intracellular signaling cascades. The protein's activation can be inhibited by small molecules like peptides or antibodies that bind to its extracellular domain.

Please enquire for more information about Fmoc-Trp-Rink-Amide MBHA Resin including the price, delivery time and more detailed product information at the technical inquiry form on this page

m-dPEG®4-Azide (Azido-m-dPEG®4) is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®4-Azide (Azido-m-dPEG®4) is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

CoV-2 IgG S1 antibody binds to both SARS-CoV and SARS-CoV-2 (COVID-19) with high affinity at amino acids 318-510 in the S1 domain of the Spike protein and can be used in ELISA assays. SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies. It has recently been shown that SARS is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics.
Recombinant Anti Human SARS CoV-2 IgG1 Kappa Spike S1 is a recombinant monoclonal antibody derived from HEL293 cells, which recognizes the SARS-CoV and SARS-CoV-2 Spike glycoprotein. CoV-2 IgG S1 Antibody binds to both SARS-CoV and SARS-CoV-2 with high affinity at amino acids 318-510 (RBD, Receptor Binding Domain) in the S1 subunit of the Spike protein.  The native monoclonal antibody was generated by sequencing peripheral blood lymphocytes of a patient exposed to the SARS-CoV.  The ELISA Plate was coated with the target proteins at 5 µg/ml. Primary antibodies were titrated on a 3-fold serial dilution starting at 125 ng/ml,  CoV-2 IgG S1 antibody recognises SARS-CoV-2 spike protein subunit 1 (aa 1-674), or 41.6 ng/ml CoV-2 IgG S1 antibody recognised spike protein from SARS-CoV (subunit 1, aa 1-666) and SARS-CoV-2 (subunit 1, aa 1-674). Secondary antibody anti-human IgG conjugated to HRP used in the assay, at 1:4000 concentration. This product was purified through Protein A affinity and avaiable in the formulation: 1mg/ml in PBS and 0.02% Proclin 300F.

Obestatin is a neuropeptide that was first isolated from the mouse and rat hypothalamus. The Obestatin (Mouse, Rat)-EIA Kit is an in-house ELISA assay for the detection of mouse and rat obestatin. This kit can be used to detect obestatin in serum, plasma, or cell culture supernatant samples. It is a useful tool for studying the role of this peptide in various biological processes.

The ALB, GIG20, GIG42 MS Calibrator (25nmol) is a Proteomics Tools product that has been designed to support the identification of biologically active peptides in proteomics. The ALB, GIG20, GIG42 MS Calibrator (25nmol) is a tryptic peptide derived from human serum albumin and can be used as a precursor for the identification of other tryptic peptides in proteomic samples. The New England Peptide Company offers this product at a competitive price and with high quality.

Somatostatin is a peptide hormone that is produced by the hypothalamus and inhibits the release of growth hormones, stimulates the release of insulin from the pancreas, and inhibits the release of glucagon from the pancreas. Somatostatin also has biological properties that inhibit neuronal death in combination therapy groups. It has been shown to have cell factor activity which may contribute to its antitumor activity. Somatostatin also has pro-apoptotic properties in vitro assays at physiological levels, making it an excellent target for cancer therapy.

Biotin-dPEG®3-MAL is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Biotin-dPEG®3-MAL is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.