Peptides

Anti P2X4 (370-388) (Rat) Serum is a research tool that can be used to measure the activation of P2X4 receptors. It is suitable for use in antibody-based applications, such as Western blotting and immunohistochemistry. Anti P2X4 (370-388) (Rat) Serum is a high purity product that has been extensively characterized by NMR spectroscopy, mass spectrometry, and amino acid analysis. The purified peptide is supplied at a concentration of 1 mg/mL in phosphate buffered saline with 0.02% sodium azide as preservative and 50% glycerol as cryoprotectant. The product is sold under reference number CAS No. 74941-79-6 and has the molecular weight of 3199.87 Da. Anti P2X4 (370-388) (Rat) Serum can be used to study protein interactions, receptor ligand pharmacology, ion

CGRP, humanAntiserum is a peptide that is the major peptide in the calcitonin gene-related peptide family. CGRP inhibits the activation of certain ion channels, which are proteins in cell membranes that allow ions to cross the membrane. It is also known to be an activator of certain G protein-coupled receptors, as well as a ligand for some receptor types. CGRP has been shown to play a role in vascular smooth muscle contraction and pain regulation.

m-dPEG®24-Amido-dPEG®24-DSPE is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®24-Amido-dPEG®24-DSPE is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

CH3O-PEG-NH2 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. CH3O-PEG-NH2 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Carboxyl-dPEG®4-(m-dPEG®12)3 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Carboxyl-dPEG®4-(m-dPEG®12)3 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

NT 3 Mouse is a peptide that belongs to the group of activators. It is used as a research tool for its ability to activate the protein tyrosine kinase receptor, and is also an antibody. NT 3 Mouse has been shown to be an inhibitor of ion channels and protein interactions. This peptide binds to the receptor and blocks the binding of ligands such as ATP, which are necessary for signaling. The CAS number for NT 3 Mouse is 51101-54-6.

Please enquire for more information about Fmoc-N-Lys-(dPEG®12-Biotin)-OH-(Acid) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Gly-Gly-His is a peptide that binds to copper and forms a complex. It has been shown to have antimicrobial properties in a model system using human serum. Gly-Gly-His is a diazonium salt that reacts with histidine, leading to the formation of an amide bond. The histidine residue can be replaced by other amino acids, such as lysine, arginine, or asparagine. This peptide also has calcium binding properties and has been shown to have biological properties in the femoral vein of rats.

APOA1 MS Calibrator-2 is a New England Peptide that is a member of the apolipoprotein A family. APOA1 MS Calibrator-2 has been used in proteomics research as a control peptide for quantitative analysis of Apo-AI by MALDI TOF MS. It has also been used as an internal standard in mass spectrometry experiments to quantify Apo-AI and other proteins.

Angiotensin converting enzyme (ACE) heavy tryptic peptide standard for use in proteomics studies. ACE is involved in the regulation of blood pressure through converting inactive angiotensin I to active angiotensin II and also degrading active Bradykinin.

Anti Leptin (Rat) Serum is a peptide that is used as a research tool to activate the receptor. Anti Leptin (Rat) Serum has been shown to inhibit protein interactions and may be used in pharmacology to study the effects of leptin on ion channels. This antibody can be used for immunohistochemistry, Western blotting, and ELISA.

Neuromedin U Precursor-Related Peptide 33 (Rat, Mouse) is a research tool that can be used to study the effects of neuromedin U on the activation of receptors. This peptide is a ligand for the receptor and has been shown to inhibit ion channels. Neuromedin U Precursor-Related Peptide 33 (Rat, Mouse) may also be used as an antibody or in protein interactions studies. This product is made from high purity materials and can be used in pharmacology and life science experiments.

Adrenomedullin (Human, 1-25) is a vasopressor fragment of the human peptide hormone adrenomedulin. This product has a disulfide bond between Cys16-Cys21 and is available as a 0.5mg vial.

FGF13 is a protein that belongs to the FGF family of growth factors. It is a ligand for FGFR1 and FGFR2, two receptors that are involved in bone and cartilage formation. FGF13 also has been shown to be an activator of the receptor tyrosine kinase MET, which is important for cell proliferation and differentiation. This protein shows no activity against FGFR3 or FGFR4.
FGF13 can be used as a research tool for studying protein interactions and as an antibody for immunoprecipitation or Western blotting. It can also be used to block certain cellular pathways by inhibiting the activation of different receptors, such as the EGFR receptor.

An inhibitor of β-Glucuronidase

HMGB1 is a protein that belongs to the family of high-mobility group box proteins. It is involved in regulating the release of inflammatory mediators and cytokines, such as IL-1β, IL-6, TNF-α and MCP-1. HMGB1 also plays a role in activation of neutrophils and macrophages. The recombinant form of HMGB1 has been shown to be an excellent research tool for studying protein interactions and receptor ligand interactions. High purity HMGB1 can be used as a pharmacological inhibitor or activator.

A Ceruloplasmin Heavy Tryptic Peptide Standard for use in protein identification and quantitation studies. Ceruloplasmin is a serum ferroxidase key to transporting copper in the blood. It also plays a role in iron metabolism regulation and the pathogenesis of Wilson disease. Furthermore it has been found in elevated levels during inflammation.

MOCA is a small peptide with anti-inflammatory properties that binds to the receptor IL-1R. It has been shown to inhibit sodium currents in neurons by binding to the Na+ channel and preventing the influx of sodium ions, which leads to an inhibition of action potentials. MOCA has also been shown to bind with high affinity to the IL-1R and blocks its activity. This inhibition of IL-1R leads to decreased production of proinflammatory cytokines.
MOCA has not been shown to have any affinity for other receptors or ligands.

A potent vasoconstrictor (Source rat, 110-123) containing disulfide bonds between Cys8-Cys13 and available as a 0.5mg vial.  
Urotensin II is a peptide involved in biological systems such as the nervous, endocrine, cardiovascular and renal and in rats it is primarily found in brainstem and spinal cord motor neurons. Like that of urotensin II-related peptide, urotensin II contains the hexapeptide -CYS-TYR-LYS-TRP-PHE-CYS- known as the core and this is crucial to its biological function.
Urotensin II can also increase the concentration of intercellular calcium through binding to its G protein coupled receptor: urotensin-II receptor which causes the activation of Protein kinase C followed by the activation of Phospholipase C.
UT-II has been shown to have a wide range of physiological effects in rats, including vasoconstriction, modulation of blood pressure, and stimulation of the release of aldosterone and vasopressin.
In addition to its physiological effects, UT-II has also been implicated in the pathogenesis of various cardiovascular and metabolic disorders, including hypertension, heart failure, and diabetes. Inhibition of UT-II signaling has been suggested as a potential therapeutic target for these conditions.

NHS-m-dPEG®(MW = 1214) is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. NHS-m-dPEG®(MW = 1214) is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

DBCO-dPEG®12-TFP Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. DBCO-dPEG®12-TFP Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

CEP1, C-Terminally Encoded Peptide 1 is involved in the regulation of plant growth and abiotic stress through cellular communication.

Anti-Alpha-Endorphin Serum is a research tool that can be used to study the effects of peptides on ion channels. This serum has been shown to inhibit the production of alpha-endorphin and beta-endorphin by binding to the receptor. It also blocks ligand binding, which prevents activation of the receptor. Anti-Alpha-Endorphin Serum is an antibody that binds to both peptides and receptors. This serum is high purity, with a CAS number of 122702-10-2.

Tyr-3/Trp- 5 Monooxygenase Activation Protein Zeta (TAZ) is an enzyme that is involved in the regulation of cellular proliferation, differentiation and apoptosis. This protein contains a domain with high similarity to the Tyr-3/Trp-5 monooxygenase activation domain and has been shown to be an activator of this enzyme. TAZ also interacts with ion channels and has been shown to inhibit their function. TAZ is a recombinant human protein produced in E. coli cells and purified by a proprietary process that yields a high purity product.

PAH MS Calibrator-3 is a tryptic peptide that is used as an internal standard in the analysis of PAHs. It is a Biologically Active Peptide that can be used in proteomics and peptides and biochemicals research.
PAH MS Calibrator-3 is a Phe-4-monooxygenase, which converts Phenylalanine to the PAH, 4-hydroxyphenylpyruvic acid. This product can be used as an internal standard for PAHs, including phenanthrene, anthracene, fluoranthene, pyrene, benzo(a)pyrene and chrysene.

DNP-Pro-Leu-Gly is a synthetic substrate of carboxypeptidase A. It is a peptide that has been shown to have potential as an anti-ulcer agent in animal studies. DNP-Pro-Leu-Gly is able to activate the enzyme carboxypeptidase A by binding to its active site and mimicking the natural substrate, tryptophan. The peptide has also been shown to inhibit collagen degradation in vitro, which may be due to its ability to bind collagen and inhibit the activity of collagenase enzymes.

IL-8 (1-72) is a chemokine that belongs to the IL-8 family. It is a potent neutrophil chemoattractant and activator. IL-8 (1-72) has been shown to stimulate the production of other proinflammatory cytokines, such as IL-6, and to promote leukocyte migration across endothelial cells in vitro.

m-dPEG®48-NH-CO(CH2)3CO-TFP Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®48-NH-CO(CH2)3CO-TFP Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

BrBzGCp2 (p BrBzGSH(Cp)2) is a GLO1 inhibitor with antitumor activities, relieving anxiety, and is useful in researching neurological disorders.