Modulateurs d'enzymes
Les modulateurs d'enzymes sont des composés qui peuvent augmenter ou inhiber l'activité des enzymes, régulant ainsi la vitesse des réactions biochimiques. Ces modulateurs jouent un rôle essentiel dans le contrôle des voies métaboliques, de la signalisation cellulaire et de divers processus physiologiques. Les modulateurs d'enzymes sont largement utilisés dans la recherche et le développement de médicaments pour étudier les fonctions enzymatiques et développer des agents thérapeutiques. Chez CymitQuimica, nous proposons une gamme complète de modulateurs d'enzymes de haute qualité pour soutenir vos recherches sur la régulation enzymatique et la découverte de médicaments.
Sous-catégories appartenant à la catégorie "Modulateurs d'enzymes"
693 produits trouvés pour "Modulateurs d'enzymes"
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Crenolanib
CAS :Inhibits type III tyrosine kinases (PDGFRα, PDGFRβ, FLT3)Formule :C26H29N5O2Degré de pureté :Min. 95%Couleur et forme :White To Yellow SolidMasse moléculaire :443.54 g/molBMS 754807
CAS :A reversible inhibitor of IGF-1R kinase and insulin receptor. Has anti-growth effects in mesenchymal, epithelial and hematopoietic tumor types. Synergistic with other cytotoxic, hormonal and targeted anti-cancer therapy.
Formule :C23H24FN9ODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :461.49 g/molAceclofenac - Bio-X ™
CAS :Acecelofenac is a non-steroidal anti-inflammatory drug that is used in the treatment of osteoarthritis, arthritis, and ankylosing spondylitis. This drug is also a cyclooxygenase inhibitor and works by inhibiting this enzyme so that pain and inflammation is reduced.Formule :C16H13Cl2NO4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :354.18 g/molIrsogladine maleate - Bio-X ™
CAS :Irsogladine is a gastroprotective drug that is used for the treatment of GERD and gastric ulcers. This drug also has antioxidant properties. Irsogladine is a phosphodiesterase-4 inhibitor and increases levels of cAMP. It helps to prevent and heal damage to the stomach lining.Formule :C13H11Cl2N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :372.16 g/molMGCD 265
CAS :Inhibits MET, VEGFR1-3, Tie and Ron tyrosine kinases; antineoplasticFormule :C26H20FN5O2S2Degré de pureté :Min. 95%Masse moléculaire :517.60 g/molThioglycosyl Naphthalimide
CAS :Thioglycosyl Naphthalimide is a highly potent human O-GlcNAcase (hOGA) inhibitor with good selectivity against human β-N-acetylhexosaminidase B (HsHexB).Formule :C30H40N4O7SDegré de pureté :Min. 95%Masse moléculaire :600.73 g/mol(-)-Huperzine A
CAS :Acetylcholinesterase inhibitor; therapy for Alzheimer's diseaseFormule :C15H18N2ODegré de pureté :(%) Min. 98%Couleur et forme :PowderMasse moléculaire :242.32 g/molLY 411575
CAS :Potent inhibitor of γ-secretase. LY 411575 inhibited production of amyloid β (Aβ) peptides with IC50 of 0.078 nM in vitro as well as decreased levels of Aβ40 and Aβ42 amyloids in brain of a mouse model for Alzheimer’s disease. In vitro studies confirmed that LY 411575 inhibited cleavage of Notch receptor at S3 site with IC50 of 0.39 nM, which blocked Notch activation and downstream signalling, leading to apoptosis in primary and immortalized Kaposi's sarcoma cells.Formule :C26H23F2N3O4Degré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :479.48 g/molMRK 560
CAS :γ-secretase inhibitor; reduces amyloid-β in brainÂ
Formule :C19H17ClF5NO4S2Degré de pureté :Min. 95%Masse moléculaire :517.92 g/molGNE 6776
CAS :Specific inhibitor of the ubiquitin specific protease-7 (USP7), which is a validated deubiquitinase of the E3 ubiquitin-protein ligase MDM2. The compound inhibits the USP7 deubiquitinase activity by binding to acidic amino acid residues important for the interaction with ubiquitin. Induces tumor cell death and enhances cytotoxicity of chemotherapeutic agents.Formule :C20H20N4O2Degré de pureté :Min. 95%Masse moléculaire :348.4 g/molIdelalisib
CAS :Idelalisib is a pharmaceutical drug that functions as a PI3Kδ inhibitor, developed through synthetic chemical processes. Its mode of action involves selectively targeting and inhibiting phosphatidylinositol 3-kinase delta (PI3Kδ), a lipid kinase that plays a crucial role in the signaling pathways responsible for cell proliferation, survival, and differentiation. By inhibiting this enzyme, Idelalisib effectively impedes pathways that are often hyperactivated in certain hematologic malignancies, thereby exerting antitumor effects.Formule :C22H18FN7ODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :415.42 g/molSRT1720 hydrochloride
CAS :SIRT1 activatorFormule :C25H23N7OS·xHClDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :469.56 g/molAG 221
CAS :Inhibitor of isocitrate dehydrogenase 2Formule :C19H17F6N7ODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :473.38 g/molDCC 2036
CAS :Inhibits multiple tyrosine kinases (Abl1, Src family kinases, Tie-2 and VEGFR-2)Formule :C30H28FN7O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :553.59 g/molPeiminine
CAS :Inhibitor of TGF-α, CTGF, ERK1/2, NF-κB and FasL; anti-inflammatoryFormule :C27H43NO3Degré de pureté :Min. 98 Area-%Masse moléculaire :429.64 g/molSGC AAK1 1
CAS :Dual inhibitor of the adaptor protein 2-associated kinase 1 (AAK1) and BMP2-inducible kinase (BMP2K) with IC50 values of 270 nM and 1 μM, respectively. In a recent study, SGC AAK1 1 stabilised β-catenin, inhibited phosphorylation of the AP2 complex subunit mu protein (AP2M1) and activated Wnt signalling in in vitro experiments._x000D_Formule :C21H25N5O3SDegré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :427.52 g/molEbselen
CAS :Ebselen is a non-toxic organoselenium compound with antioxidant, anti-inflammatory and cytoprotective properties. Ebselen is an inhibitor of lipoxygenases, nitric oxide (NO) synthases, protein kinase C, H+/K+-ATPase, thioredoxin reductase and NADPH oxidase. Recently, ebselen has been identified by several studies as a covalent inhibitor of the main protease Mpro from coronaviruses. For the SARS-CoV-2 main protease Mpro, the IC50 value is 0.67 μM and EC50 is 4.57 μM.Formule :C13H9NOSeDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :274.18 g/molNilotinib HCl monohydrate - Bio-X ™
CAS :Nilotinib is a kinase inhibitor that is used for the treatment of Chronic Myeloid Leukemia (CML). This drug is also used for the treatment of CML that is resistant to imatinib. Nilotinib inhibits the tyrosine kinase activity of the BCR-ABL protein. It also inhibits PDGFR and c-kit.
Formule :C28H22F3N7O•HCl•H2ODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :583.99 g/molLY 2886721
CAS :Inhibitor of BACE1 proteaseFormule :C18H16F2N4O2SDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :390.41 g/mol3-(4-Phenylbutyl)-4-propyloxetan-2-one
CAS :Cis/trans-form of GK 563 [2351820-19-2]Formule :C16H22O2Degré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :246.34 g/mol
