Antitumor agent-195

Ref. TM-T205391

Informations sur le produit

• Nom: Antitumor agent-195
• Marque: Targetmol
• Description: Antitumor agent-195 (compound 16c) is a dual-targeting agent that simultaneously targets STAT3 and NQO1. At a concentration of 1 μM, it significantly inhibits the phosphorylation of STAT3 at the Tyr705 site and effectively induces apoptosis in MDA-MB-231 and MDA-MB-468 breast cancer cells. As a substrate of NQO1, Antitumor agent-195 markedly increases ROS production, causing severe DNA damage in a dose-dependent manner. It also demonstrates strong antitumor properties in MDA-MB-231 xenograft models.

Propriétés chimiques

• Masse moléculaire: 378.42
• Formule: C₂₂H₂₂N₂O₄
• Couleur/Forme: Solid