Etravirine

CAS : 269055-15-4

Ref. TM-T2551

Informations sur le produit

• Nom: Etravirine
• Synonymes: TMC125, R165335, 4-((6-Amino-5-Bromo-2-((4-Cyanophenyl)Amino)-4-Pyrimidinyl)Oxy)-3,5-Dimethyl-Benzonitrile, 4-(6-Amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yloxy)-3,5-dimethylbenzonitrile, 4-({6-Amino-5-Bromo-2-[(4-Cyanophenyl)Amino]Pyrimidin-4-Yl}Oxy)-3,5-Dimethylbenzonitrile, 4-({6-Amino-5-brom-2-[(4-cyanphenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzolcarbonitril, 4-[[6-Amino-5-Bromo-2-[(4-Cyanophenyl)Amino]-4-Pyrimidinyl]Oxy]-3,5�CDimethylbenzonitrile, 4-[[6-Amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile, 6-Amino-5-Bromo-4-(4-Cyano-2,6-Dimethylphenoxy)-2-(4-Cyanophenylamino)Pyrimidine, Benzonitrile, 4-((6-amino-5-bromo-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethyl-, Etravirine [INN], Etravirine [USAN:INN], Intelence, R 165335, R165335-Tmc125, Tmc 125, Tmc125, Unii-0C50Hw4Fo1
• CAS: 269055-15-4

Description

Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that confer resistance to the two most commonly prescribed first-generation NNRTIs. It can bind the enzyme reverse transcriptase (RT) in multiple conformations, both for native and mutant RT, thereby blocking the enzymatic activity of RT.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 435.28
• Formule: C₂₀H₁₅BrN₆O
• Degré de pureté: 99.56%
• Couleur/Forme: White To Off-White Solid