IMM-01

CAS : 218795-74-5

Ref. TM-T25529

Informations sur le produit

• Nom: IMM-01
• Synonymes: IMM01, IMM 01
• CAS: 218795-74-5

Description

IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin filaments, and their organization with microfilaments to establish and maintain cell polarity during migration and asymmetric division. GTP-bound Rho activates mDia family members by disrupting the interaction between the DID and DAD autoregulatory domains, which releases the FH2 domain to modulate actin and microtubule dynamics[1].

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 267.35
• Formule: C₁₂H₁₇N₃O₂S
• Degré de pureté: 98.81%
• Couleur/Forme: Solid