X-376

CAS : 1365267-27-1

Ref. TM-T3550

Informations sur le produit

• Nom: X-376
• Synonymes: Ensartinib, X-396
• CAS: 1365267-27-1

Description

X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inhibits ALK kinase, ALK fusion proteins, and ALK point mutation variants. Inhibition of ALK leads to the disruption of ALK-mediated signaling and eventually inhibits tumor cell growth in ALK-expressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 547.41
• Formule: C₂₅H₂₅Cl₂FN₆O₃
• Degré de pureté: 98.72%
• Couleur/Forme: Solid