NX-2127

CAS : 2416131-46-7

Ref. TM-T73463

Informations sur le produit

• Nom: NX-2127
• Synonymes: NX2127, NX 2127

Description

NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferative activity and inhibits the proliferation of BTKC481S mutant TMD8 cells.NX-2127 potently catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3) at 25 nM and 54 nM, respectively. NX-2127 is associated with the immune system, stimulating T cell activation and increasing IL-2 production in primary human T cells.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 719.83
• Formule: C₃₉H₄₅N₉O₅
• Degré de pureté: 98.11%
• Couleur/Forme: Solid