Deoxynivalenol

CAS : 51481-10-8

Ref. TR-D243900

Informations sur le produit

• Nom: Deoxynivalenol
• Synonymes: (3a,7a)-12,13-Epoxy-3,7,15-trihydroxytrichothec-9-en-8-one, Spiro[2,5-methano-1-benzoxepin-10,2'-oxirane], trichothec-9-en-8-one deriv., 4-Deoxynivalenol, 4-Desoxynivalenol, DON, Dehydronivalenol, NSC 269144, Vomitoxin, (3α,7α)-12,13-Epoxy-3,7,15-trihydroxytrichothec-9-en-8-one, Nsc 269144, Spiro[2,5-methano-1-benzoxepin-10,2′-oxirane], trichothec-9-en-8-one deriv., Trichothec-9-en-8-one, 12,13-epoxy-3,7,15-trihydroxy-, (3α,7α)-

Description

Applications Deoxynivalenol is a tricothecene mycotoxin and potent protein synthesis inhibitor. Deoxynivalenol exhibits cytotoxic activity in vivo via the ribotoxic stress response. Deoxynivalenol induces p38-mediated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF-κB into the nucleus.Environmental contaminants; Food contaminants
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bae, et al.: Toxicol. Sci., 105, 59 (2008), Shi, et al.: Toxicol. Sci., 109, 247 (2009), Krishnaswamy, et al.: Free Radic. Biol. Med., 49 50 (2010),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 296.32
• Formule: C₁₅H₂₀O₆
• Couleur/Forme: White To Beige
• InChI: InChI=1S/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/m1/s1
• Code InChI: InChIKey=LINOMUASTDIRTM-QGRHZQQGSA-N
• SMILES: CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)([C@]34CO4)[C@@]2(CO)[C@H](O)C1=O