Gefitinib-d6

CAS : 184475-35-2

Ref. TR-G304008

Informations sur le produit

• Nom: Gefitinib-d6
• Synonymes: N-(3-chloro-4-fluorophenyl)-6-(1,1,2,2,3,3-hexadeuterio-3-morpholin-4-ylpropoxy)-7-methoxyquinazolin-4-amine, (3-Chloro-4-fluorophenyl)[7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-yl]amine, 4-(3-Chloro-4-fluorophenylamino)-7-methoxy-6-[3-(4-morpholinyl)propoxy]quinazoline, 4-(3′-Chloro-4′-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline, 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-, Akos 91371, Gefitinib, Gefitinib Base, Gefitinib(TINIBS), Gefitinib, Iressa, ZD1839, Gefonib, Geftinib, N-(3-Chloro-4-Fluoro-Phenyl)-7-Methoxy-6-(3-Morpholin-4-Ylpropoxy)Quinazolin-4-Amine, N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine, N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine, Zd 1839, Zd1839, Iressa

Description

Applications Gefitinib-d6 is the labeled version of Gefitinib (G304000), which is an antineoplastic.
References Anderson, N.G., et al.: Int. J. Cancer, 94, 774 (2001), Hirata, A., et al.: Cancer Res., 62, 2554 (2002), Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003), Tamura, K., et al.: Expert Opin. Pharmacother., 6, 985 (2005)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 452.939
• Formule: C₂₂D₆H₁₈ClFN₄O₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)/i2D2,5D2,8D2
• Code InChI: InChIKey=XGALLCVXEZPNRQ-AQCDAZAYSA-N
• SMILES: [2H]C([2H])(Oc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC)C([2H])([2H])C([2H])([2H])N1CCOCC1