Rapamycin-13C,d3 (contains d0) Technical Grade

CAS : 53123-88-9

Ref. TR-R124003

Informations sur le produit

• Nom: Rapamycin-13C,d3 (contains d0) Technical Grade
• Synonymes: (-)-Rapamycin-13C,d3, AY 22989-13C,d3, Antibiotic AY 22989-13C,d3, Cypher-13C,d3, NSC 226080-13C,d3, RAPA-13C,d3, RPM-13C,d3, Rapammune-13C,d3, Rapamune-13C,d3, SIIA 9268A-13C,d3, Sirolimus-13C,d3
• Marque: TRC

Description

Applications Labelled Rapamycin. A triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic.This compound contains aproximately 2% d0.
References Martel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977), Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993), Kahan, B.D., et al.: Lancet, 356, 194 (2000), Holmes, D.R., et al.: Circulation, 109, 634 (2004),

Propriétés chimiques

• Masse moléculaire: 918.18
• Formule: C₅₀CH₇₆D₃NO₁₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,31-17+,35-25+/t30?,32?,33?,34?,36?,37-,38-,39-,40+,42?,43-,44?,46+,47?,51+/m0/s1/i8+1D3
• Code InChI: InChIKey=QFJCIRLUMZQUOT-YKCXXMOJSA-N
• SMILES: [2H][13C]([2H])([2H])O[C@H]1C[C@@H]2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@H]([C@H](C)CC2CC[C@@H](O)[C@H](OC)C2)CC(=O)[C@H](C)/C=C(\C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)/C=C/C=C/C=C/1C