Zebularine

CAS : 3690-10-6

Ref. TR-Z276000

Informations sur le produit

• Nom: Zebularine
• Synonymes: 1-ß-D-Ribofuranosyl-2(1H)-pyrimidinone, 4-Deoxyuridine, NSC 309132, Pyrimidin-2-one ß-D-Ribofuranoside, 1-(β-<span class="text-smallcaps">D</span>-Ribofuranosyl)-1,2-dihydropyrimidin-2-one, 1-(β-<span class="text-smallcaps">D</span>-Ribofuranosyl)-2-pyrimidone, 1-b-D-Ribofuranosyl-2(1H)-pyrimidinone, 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-2(1H)-pyrimidinone, 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-2-pyrimidinone, 2(1H)-Pyrimidinone, 1-.beta.-D-ribofuranosyl-, 2(1H)-Pyrimidinone, 1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, Pyrimidin-2-one b-Ribofuranoside, Pyrimidin-2-one β-<span class="text-smallcaps">D</span>-ribofuranoside, Uridine, 4-deoxy-, 1-(β-D-Ribofuranosyl)-2-pyrimidone, 1-(beta-D-Ribofuranosyl)pyrimidin-2(1H)-one, 2(1H)-Pyrimidinone, 1-β-D-ribofuranosyl-

Description

Applications It is a cytidine analogue, cytidine deaminase inhibitor, and DNA demethylating agent.
References Driscoll, J., et al.: J. Med. Chem., 34, 3280 (1991), Ueki, T., et al.: Cancer Res., 60, 1835 (2000),Sherr, C., et al.: Cell, 116, 235 (2004), Dote, H., et al.: Clin. Cancer Res.,11, 4571 ( 2005),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 228.20
• Formule: C₉H₁₂N₂O₅
• Couleur/Forme: Neat
• InChI: InChI=1S/C9H12N2O5/c12-4-5-6(13)7(14)8(16-5)11-3-1-2-10-9(11)15/h1-3,5-8,12-14H,4H2/t5-,6-,7-,8-/m1/s1
• Code InChI: InChIKey=RPQZTTQVRYEKCR-WCTZXXKLSA-N
• SMILES: O=c1ncccn1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O