CAS 1000819-21-5

Formula: C37H50N4O3S

InChI: InChI=1S/C37H50N4O3S/c1-23-18-24(2)20-26(19-23)33-30(11-13-39-12-10-29(25(3)22-39)35(42)40-14-16-44-17-15-40)31-21-32(45-34(31)38-33)37(4,5)36(43)41-27-6-7-28(41)9-8-27/h18-21,25,27-29,38H,6-17,22H2,1-5H3

InChI key: ATYOFXVORANGGC-UHFFFAOYSA-N

SMILES: CC1CN(CCC1C(=O)N2CCOCC2)CCC3=C(NC4=C3C=C(S4)C(C)(C)C(=O)N5C6CCC5CC6)C7=CC(=CC(=C7)C)C

GnRH-R antagonist-2

CAS: 1000819-21-5

GnRH-R antagonist-2 (Compound 44c) is a gonadotropin-releasing hormone receptor (GnRH-R) antagonist, with IC50 values of 43 nM for rat and 88 nM for human GnRH-R. It is applicable in studies related to hormone-dependent diseases such as endometriosis, breast cancer, and prostate cancer^[1].

Formula: C₃₇H₅₀N₄O₃S

Peso molecolare: 630.89

Ref: TM-T213283