CAS 1093108-50-9

Formula: C25H26F3N5O3

InChI: InChI=1S/C25H26F3N5O3/c1-32(2)22-19(14-21(34)35)23(33(3)4)31-20(30-22)13-15-5-11-18(12-6-15)29-24(36)16-7-9-17(10-8-16)25(26,27)28/h5-12H,13-14H2,1-4H3,(H,29,36)(H,34,35)

InChI key: XEOSTBFUCNZKGS-UHFFFAOYSA-N

SMILES: CN(C)C1=C(C(=NC(=N1)CC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)C(F)(F)F)N(C)C)CC(=O)O

BI-671800

CAS: 1093108-50-9

BI-671800

Formula: C₂₅H₂₆F₃N₅O₃

Purezza: ≥98%

Peso molecolare: 501.5

Ref: 54-BUP09025

BI-671800

CAS: 1093108-50-9

BI-671800 (AP-761) is a DP2/CRTH2 antagonist with IC50 values of 4.5 nM and 3.7 nM, potential for treating asthma.

Formula: C₂₅H₂₆F₃N₅O₃

Purezza: 99.19%

Colore e forma: Solid

Peso molecolare: 501.5008

Ref: TM-T14565

2-[4,6-Bis(Dimethylamino)-2-[[4-[[4-(Trifluoromethyl)Benzoyl]Amino]Phenyl]Methyl]Pyrimidin-5-Yl]Acetic Acid

CAS: 1093108-50-9

2-[4,6-Bis(Dimethylamino)-2-[[4-[[4-(Trifluoromethyl)Benzoyl]Amino]Phenyl]Methyl]Pyrimidin-5-Yl]Acetic Acid

Formula: C₂₅H₂₆F₃N₅O₃

Purezza: 99.06%

Peso molecolare: 501.5

Ref: 54-PC108557

BI-671800

CAS: 1093108-50-9

Purezza: 99.06%

Ref: IN-DA0095AG

BI-671800

CAS: 1093108-50-9

2-(4,6-Bis(dimethylamino)-2-(4-(4-(trifluoromethyl)benzamido)benzyl)pyrimidin-5-yl)acetic acid

Formula: C₂₅H₂₆F₃N₅O₃

Purezza: 99.06%

Peso molecolare: 501.5

Ref: IN-DG01120973

BI-671800

CAS: 1093108-50-9

BI-671800 is a nitro compound that has been shown to be an effective therapy for asthma by reducing the production of inflammatory molecules. It has been shown to inhibit the enzyme glutaminyl cyclase, which regulates the level of glutamate in cells. This drug also reduces the production of pro-inflammatory cytokines and nitric oxide through its ability to inhibit the expression of CRTH2 receptors. BI-671800 has been shown to be safe and have a good safety profile. The drug has also demonstrated statistically significant effects on autoimmune diseases in animal models. BI-671800 is not active against tautomers, but it does bind to glutaminyl residues on proteins with high affinity.

Formula: C₂₅H₂₆F₃N₅O₃

Purezza: Min. 95%

Peso molecolare: 501.5 g/mol

Ref: 3D-TTB10850