CAS 11027-63-7

Agnuside

Descrizione:

Agnuside, con il numero CAS 11027-63-7, è un composto glicosidico derivato principalmente dalla pianta Vitex agnus-castus, comunemente nota come albero della castità. È caratterizzato dalla sua struttura chimica, che include un moiety di glucosio legato a un aglicone, specificamente un composto iridoide. Agnuside è noto per le sue potenziali proprietà farmacologiche, inclusi effetti antinfiammatori, antiossidanti e regolatori ormonali, in particolare in relazione alla salute riproduttiva. È stato studiato per i suoi possibili benefici nell'alleviare i sintomi associati alla sindrome premestruale (PMS) e ad altri disturbi mestruali. Il composto viene tipicamente estratto dai frutti o dalle foglie dell'albero della castità ed è spesso utilizzato in formulazioni di medicina erboristica. In termini di solubilità, Agnuside è generalmente solubile in acqua e solventi organici, il che facilita la sua estrazione e incorporazione in varie preparazioni terapeutiche. Il suo profilo di sicurezza e efficacia sono oggetto di ricerca continua, evidenziando l'importanza di comprendere le sue interazioni biochimiche e le potenziali applicazioni terapeutiche.

Formula: C₂₂H₂₆O₁₁

InChI: InChI=1/C22H26O11/c23-8-15-17(26)18(27)19(28)22(32-15)33-21-16-11(7-14(25)13(16)5-6-30-21)9-31-20(29)10-1-3-12(24)4-2-10/h1-7,13-19,21-28H,8-9H2/t13-,14+,15+,16+,17+,18-,19+,21-,22-/m0/s1

InChI key: InChIKey=GLACGTLACKLUJX-QNAXTHAFSA-N

SMILES: O([C@H]1[C@]2([C@]([C@H](O)C=C2COC(=O)C3=CC=C(O)C=C3)(C=CO1)[H])[H])[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O

Sinonimi:

• (-)-Buddlejoside A
• (1S,4aR,5S,7aS)-1,4a,5,7a-Tetrahydro-5-hydroxy-7-[[(4-hydroxybenzoyl)oxy]methyl]cyclopenta[c]pyran-1-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
• Agnoside
• Agnuside WITH HPLC
• Agnuside(P)
• Chasteberry Oil
• [(1R,2S,6S,7S)-7-Hydroxy-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-oxabicyclo[4.3.0]nona-4,8-dien-9-yl]methyl 4-hydroxybenzoate
• [(1S,4aR,5S,7aS)-1-(beta-D-glucopyranosyloxy)-5-hydroxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-7-yl]methyl 4-hydroxybenzoate
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1S,4aR,5S,7aS)-1,4a,5,7a-tetrahydro-5-hydroxy-7-[[(4-hydroxybenzoyl)oxy]methyl]cyclopenta[c]pyran-1-yl
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 1,4a,5,7a-tetrahydro-5-hydroxy-7-[[(4-hydroxybenzoyl)oxy]methyl]cyclopenta[c]pyran-1-yl, (1α,4aα,5α,7aα)-
• (1S,4aR,5S,7aS)-1,4a,5,7a-Tetrahydro-5-hydroxy-7-[[(4-hydroxybenzoyl)oxy]methyl]cyclopenta[c]pyran-1-yl β-D-glucopyranoside
• β-D-Glucopyranoside, 1,4a,5,7a-tetrahydro-5-hydroxy-7-[[(4-hydroxybenzoyl)oxy]methyl]cyclopenta[c]pyran-1-yl, (1α,4aα,5α,7aα)-
• Agnuside
• β-D-Glucopyranoside, (1S,4aR,5S,7aS)-1,4a,5,7a-tetrahydro-5-hydroxy-7-[[(4-hydroxybenzoyl)oxy]methyl]cyclopenta[c]pyran-1-yl
• Beta-Caryophyllene CAS 87-44-5
• [(1S,4aR,5S,7aS)-5-hydroxy-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-7-yl]methyl 4-hydroxybenzoate
• Agnuside Q: What is the storage condition of
• Agnusid
• Agnuside USP/EP/BP
• OLEUMVITICISNEGUNDO Oil
• Vitex negundo oil，Agnuside
• Agnuside Q: What is the CAS Number of
• Vitex Oil
• Agnuside chasteberry oil
• Agnuside Q: What are the applications of
• AgnusideQ: What is
• [(1R,4aS,5R,7aR)-5-hydroxy-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-7-yl]methyl 4-hydroxybenzoate
• Agnuside (25 mg)

Agnuside

CAS: 11027-63-7

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Formula: C₂₂H₂₆O₁₁

Colore e forma: Off-White Powder

Peso molecolare: 466.14751

Ref: 45-1012203

Agnuside

CAS: 11027-63-7

Agnuside

Formula: C₂₂H₂₆O₁₁

Purezza: 99%

Peso molecolare: 466.44

Ref: 54-BUP02902

Agnuside

CAS: 11027-63-7

Formula: C₂₂H₂₆O₁₁

Peso molecolare: 466.44

Ref: 7W-GC8652

Agnuside

CAS: 11027-63-7

Formula: C₂₂H₂₆O₁₁

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 466.4352

Ref: IN-DA008R0N

Agnuside (Standard)

CAS: 11027-63-7

Agnuside (Standard) is a reference standard for research and analysis in studies involving Agnuside. Agnuside (chasteberry oil) inhibits COX-2 (IC₅₀: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, and 82.1% of P-glycoprotein (P-gp) ATPase activity at concentrations of 5, 25, and 100 μM, respectively.

Formula: C₂₂H₂₆O₁₁

Colore e forma: Solid

Peso molecolare: 466.4352

Ref: TM-TMSM-2837

Agnuside

CAS: 11027-63-7

Agnuside analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₂H₂₆O₁₁

Purezza: (HPLC) ≥99%

Colore e forma: Powder

Peso molecolare: 466.44

Ref: 11-0235S

Agnuside

CAS: 11027-63-7

Agnuside has anti-arthritic activity, it also shows inhibition of vascular permeability and leukocyte migration in vivo.It inhibited an array of pro-inflammatory mediators (PGE(2) and LTB(4)) and T-cell-mediated cytokines (IL-2, TNF-α, IFN-γ, IL-4, IL-10, IL-17).

Formula: C₂₂H₂₆O₁₁

Purezza: 95%~99%

Peso molecolare: 466.439

Ref: BP-BP0125

Agnuside

Prodotto controllato

CAS: 11027-63-7

Applications Agnuside is an known iridoid glycoside found in Vitex herbs or plants. Agnuside have been used in various applications including in the treatment of premenstrual syndrome and regulation of menopause symptoms. This is mainly due to the fact that Agnuside exhibits estrogen-like activities as it interacts with estrogen receptors (ER-alpha) and estrogen receptor-regulated pregesterone receptors. Recent studies have also evaluated Agnuside for the probable mechanism of anti-arthritic activity, which suggested the possible development of Agnuside as a therapeutic agent in the treatment of arthritis by the modulation of the host immune response.
References Pandey, A., et al.: Inflamm. Rsch., 61, 293 (2012); Leitao, S.G., et al.: Revista. Brasileira. Farmacognosia., 21, 874 (2011); Hu, Y., et al.: J. Pharma. Pharmacol., 59, 1307 (2007);

Formula: C₂₂H₂₆O₁₁

Colore e forma: Neat

Peso molecolare: 466.44

Ref: TR-A427020

Agnuside

CAS: 11027-63-7

Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration.

Formula: C₂₂H₂₆O₁₁

Purezza: 99.08% - 99.81%

Colore e forma: Orangish-Yellow To Light Yellow Liquid

Peso molecolare: 466.4352

Ref: TM-T3868

Agnuside

CAS: 11027-63-7

((1S,4aR,5S,7aS)-5-Hydroxy-1-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-7-yl)methyl 4-hydroxybenzoate

Formula: C₂₂H₂₆O₁₁

Purezza: 98%

Peso molecolare: 466.44

Ref: IN-DG112831

Agnuside

CAS: 11027-63-7

Natural glycoside

Formula: C₂₂H₂₆O₁₁

Purezza: ≥ 98.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 466.44

Ref: 5G-89155

Agnuside

CAS: 11027-63-7

Formula: C₂₂H₂₆O₁₁

Peso molecolare: 466.4

Ref: BE-RMT10805

Agnuside

CAS: 11027-63-7

Purezza: 98%

Peso molecolare: 466.4389954

Ref: 10-F866383

Agnuside

CAS: 11027-63-7

Formula: C₂₂H₂₆O₁₁

Peso molecolare: 466.44

Ref: ST-EA-CP-A176000

Agnuside

CAS: 11027-63-7

Agnuside is a diterpenoid compound, which is a phytoconstituent primarily sourced from the plant Vitex agnus-castus, commonly known as chaste tree. This compound is extracted from the fruit of the plant through a series of isolation and purification processes aimed at preserving its chemical integrity.

Formula: C₂₂H₂₆O₁₁

Purezza: Min. 95 Area-%

Colore e forma: Brown Powder

Peso molecolare: 466.44 g/mol

Ref: 3D-MA08289