CAS 1144044-02-9

Formula: C33H34N7Na2O7P

InChI: InChI=1S/C33H36N7O7P.2Na/c1-3-16-38-22-30(41)39-28(17-23-12-14-27(15-13-23)47-48(44,45)46)32(42)37(20-26-11-7-10-25-19-36(2)35-31(25)26)21-29(39)40(38)33(43)34-18-24-8-5-4-6-9-24;;/h3-15,19,28-29H,1,16-18,20-22H2,2H3,(H,34,43)(H2,44,45,46);;/q;2*+1/p-2/t28-,29-;;/m0../s1

InChI key: KKMKZLQVDAGSOA-GDUXWEAWSA-L

SMILES: CN1C=C2C=CC=C(C2=N1)CN3C[C@H]4N([C@H](C3=O)CC5=CC=C(C=C5)OP(=O)([O-])[O-])C(=O)CN(N4C(=O)NCC6=CC=CC=C6)CC=C.[Na+].[Na+]

CWP232228

CAS: 1144044-02-9

CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.

Formula: C₃₃H₃₄N₇Na₂O₇P

Purezza: 98.87%

Colore e forma: Solid

Peso molecolare: 717.63

Ref: TM-T10904

CWP232228

CAS: 1144044-02-9

CWP232228

Formula: C₃₃H₃₄N₇Na₂O₇P

Purezza: 98.5%

Peso molecolare: 717.63

Ref: 54-BUP02509

CWP232228

CAS: 1144044-02-9

CWP232228 is a potent, selective and competitive antagonist of the beta-2 adrenergic receptor (B2AR). CWP232228 does not bind to other adrenoreceptors, including alpha-1, alpha-2, or beta-1 adrenoreceptors. CWP232228 blocks the binding of catecholamines like norepinephrine and epinephrine to B2ARs with an IC50 of 0.8 nM. CWP232228 also has high affinity for the B2AR with a Kd of 8 nM and is selective for this receptor over all other adrenoreceptors. CWP232228 is a pharmacological tool that can be used in cell biology research and in drug discovery programs to develop new drugs targeting disorders such as hypertension and asthma.

Formula: C₃₃H₃₄N₇Na₂O₇P

Purezza: Min. 95%

Peso molecolare: 717.6 g/mol

Ref: 3D-UVB04402