
CAS 1173239-39-8
:Formula:C19H22ClFN4O
InChI:InChI=1S/C19H22ClFN4O/c1-23-7-13-14(8-23)15(13)9-25(19(26)18-10-24(2)11-22-18)6-12-3-4-17(21)16(20)5-12/h3-5,10-11,13-15H,6-9H2,1-2H3/t13-,14+,15?
InChI key:KYLOBHXXQOZRKK-YIONKMFJSA-N
SMILES:CN1C[C@@H]2[C@H](C1)C2CN(CC3=CC(=C(C=C3)F)Cl)C(=O)C4=CN(C=N4)C
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PF 03463275
CAS:Orally available and central nervous system-penetrant inhibitor of GlyT1 glycine transporter SLC6A9. PF 03463275 was shown to enhance neuroplasticity and cognitive remediation in schizophrenia patients. In animal studies, PF 03463275 also influenced retina as changes in electroretinogram were detected in albino rats.Formula:C19H22ClFN4OPurezza:Min. 95%Peso molecolare:376.86 g/molPF-03463275
CAS:PF-03463275 is an orally active and selective reversible inhibitor of competitive glycine transporter protein-1 (GlyT1) with a Ki of 11.6 nM.PF-03463275 has CNSFormula:C19H22ClFN4OPurezza:99.95%Colore e forma:SolidPeso molecolare:376.856




