CAS 117399-93-6

endotelina 3

Descrizione:

L'endotelina-3 (ET-3) è un potente peptide vasocostrittore che gioca un ruolo significativo in vari processi fisiologici, inclusi l'omeostasi vascolare e la regolazione della pressione sanguigna. Fa parte della famiglia delle endotelina, che consiste di tre isoforme: endotelina-1, endotelina-2 e endotelina-3. L'ET-3 è prodotto principalmente dalle cellule endoteliali e ha un'alta affinità per i recettori dell'endotelina, in particolare i recettori ETA e ETB, che sono recettori accoppiati a proteine G. Questo peptide è composto da 21 aminoacidi ed è caratterizzato dalla sua capacità di indurre contrazione del muscolo liscio e influenzare la proliferazione cellulare. Oltre ai suoi effetti cardiovascolari, l'endotelina-3 è coinvolta nella regolazione della funzione renale e ha implicazioni in varie condizioni patologiche, tra cui ipertensione e insufficienza cardiaca. La sua sintesi e liberazione possono essere influenzate da vari fattori, tra cui ipossia e citochine infiammatorie. In generale, l'endotelina-3 è un mediatore critico nella via di segnalazione dell'endotelina, con effetti biologici diversi in diversi tessuti.

Formula: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Sinonimi:

• Endothelin-3,Human
• H-Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-Oh
• Endothelin-3 (Human, Mouse, Rabbit, Rat)
• Endothelin-3 (Human) (Porcine, Rat, Rabbit)
• Endothelin-3 (Human, Rat, Pig)
• Endothelin-3 (Human, Rat, Porcine, Rabbit)
• Endothelin 3, human, rat, ≥97% (HPLC), powder
• Human endothelin-3
• 33,34,49,50-Tetrathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecaazabicyclo[23.22.4]henpentacontane, cyclic peptide deriv.
• Endothelin 3 (Rat,Human)
• CTCFTYKDKECVYYCHLDIIW
• CTCFTYKDKECVYYCHLDIIW (DISULFIDE BRIDGE: 1-15 AND 3-11)
• Endothelin 3【rabbit】
• Endothelin 3, Human and Rat - CAS 117399-93-6 - Calbiochem
• et-3
• Anti-EDN3 antibody produced in rabbit
• CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP
• human,rat
• ET-3 (huMan, Mouse, rabbit, rat)
• H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH USP/EP/BP
• Endothelin 3 (huMan)(9CI)
• Endothelin 3 (mouse intestine)
• ET-3 (HUMAN, MOUSE, RABBIT, RAT)
• CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR- TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP(DISULFIDE BRIDGE:CYS1-CYS15, CYS3-CYS11)
• ENDOTHELIN-3
• Rat endothelin-3
• ENDOTHELIN-III, HUMAN, RAT
• Endothelin 3 huMan, ratEndothelin
• ENDOTHELIN 3 HUMAN, RAT
• L-Tryptophan, L-cysteinyl-L-threonyl-L-cysteinyl-L-phenylalanyl-L-threonyl-L-tyrosyl-L-lysyl-L-α-aspartyl-L-lysyl-L-α-glutamyl-L-cysteinyl-L-valyl-L-tyrosyl-L-tyrosyl-L-cysteinyl-L-histidyl-L-leucyl-L-α-aspartyl-L-isoleucyl-L-isoleucyl-, cyclic (1→15),(3→11)-bis(disulfide)
• ANTI-EDN3 (C-TERM) antibody produced in rabbit
• Endothelin 3【rat】
• ENDOTHELIN 3, HUMAN, RAT, 50 UG*
• ET-3 (HUMAN, RAT)
• ET-3 (HUMAN, RAT, PIG)
• M.W. 2643.04 C121H168N26O33S4
• Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridges Cys1-Cys15 and Cys3-Cys11)
• CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP HUMAN, RAT, PORCINE, RABBIT
• EDN3
• Endothelin 3【canine】
• ET-3, HUMAN AND RAT
• CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP: CTCFTYKDKECVYYCHLDIIW DISULFIDE BRIDGES CYS1-CYS15, CYS3-CYS11
• 19: PN: WO2007112069 SEQID: 10 claimed protein
• ET-3, HUMAN
• ENDOTHELIN 3, HUMAN AND RAT
• H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH (DISULFIDE BRIDGE: 1-15 AND 3-11)

Endothelin-3, Human

CAS: 117399-93-6

For cellular and molecular biology applications

Colore e forma: White to off-white, Lyophilized Powder

Ref: 02-J66312

Endothelin-3 (human, mouse, rabbit, rat)

CAS: 117399-93-6

ET-1, ET-2, and ET-3 are the products of three distinct endothelin genes. ET-2 and ET-3 are similar to ET-1, but differ in two and six amino acids, respectively. All three isopeptides produce strong in vitro vasoconstrictor and in vivo pressor responses. However, the quantitative profiles of their pharmacological activities vary greatly.

Formula: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Purezza: 93.7%

Colore e forma: White Lyophilisate

Peso molecolare: 2643.08

Ref: 01-4013291

Endothelin-3 (human, mouse, rabbit, rat)

CAS: 117399-93-6

Potent constrictor of rat blood vessels in vitro and an effective pressor agent in vivo. Endothelin-3 (ET-3) has been found in high concentrations in the brain and may regulate important functions in neurons and astrocytes, such as proliferation and development. ET-3 displays selectivity for the ETC receptor.

Formula: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Purezza: 95.0%

Colore e forma: White

Peso molecolare: 2643.08

Ref: 01-4095915

L-Tryptophan, L-cysteinyl-L-threonyl-L-cysteinyl-L-phenylalanyl-L-threonyl-L-tyrosyl-L-lysyl-L-α-aspartyl-L-lysyl-L-α-glutamyl-L-cysteinyl-L-valyl-L-tyrosyl-L-tyrosyl-L-cysteinyl-L-histidyl-L-leucyl-L-α-aspartyl-L-isoleucyl-L-isoleucyl-, cyclic (1→15),(3→

CAS: 117399-93-6

Formula: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 2643.0430

Ref: IN-DA008RJ5

Endothelin-3, human, mouse, rabbit, rat

CAS: 117399-93-6

Endothelin-3, human, mouse, rabbit, rat , is a cyclic 21 amino acid peptide. It is an endogenous neuropeptide and potent vasoconstrictor.

Formula: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 2643.04

Ref: TM-TP1175

Endothelin-3 (human, mouse, rabbit, rat) acetate

CAS: 117399-93-6

Acetate salt

Formula: C₁₂₁H₁₆₈N₂₆O₃₃S₄•(C₂H₄O₂)x

Purezza: Min. 95%

Peso molecolare: 2,643.05 g/mol

Ref: 3D-FE110371

Endothelin-3 (Human)

CAS: 117399-93-6

Endothelin-3 (ET-3) is a protein that belongs to the large family of endothelin peptides which activate the G-protein coupled receptors ETA and ETB. However ET-3 has lower affinity for the ETA receptors compared to Endothelin-1 (ET-1) and Endothelin-2 (ET-2), whereas all three endothelins have similar affinity for ETB receptors. As ETB receptors make up around 90% of the endothelin receptors found in the cerebral cortex in humans, ET-3 can be nicknamed the ‘brain endothelin’. Also through ET-3’s activation of ETB receptors, ET-3 is involved in the development of the enteric nervous system which controls within the gut, blood flow, secretion and intestinal motility. This product has disulfide bonds between Cys1-Cys and Cys3-Cys11, is sourced from Porcine, Rat and Rabbit and is available as a 0.5mg vial

Formula: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Purezza: Min. 95%

Peso molecolare: 2,643 g/mol

Ref: 3D-PED-4199-V

Endothelin-3 (Human)

CAS: 117399-93-6

Endothelin-3 (ET-3) is a protein that belongs to the large family of endothelin peptides which activate the G-protein coupled receptors ETA and ETB. However ET-3 has lower affinity for the ETA receptors compared to Endothelin-1 (ET-1) and Endothelin-2 (ET-2), whereas all three endothelins have similar affinity for ETB receptors. As ETB receptors make up around 90% of the endothelin receptors found in the cerebral cortex in humans, ET-3 can be nicknamed the ‘brain endothelin’. Also through ET-3’s activation of ETB receptors, ET-3 is involved in the development of the enteric nervous system which controls within the gut, blood flow, secretion and intestinal motility. This product has disulfide bonds between Cys1-Cys and Cys3-Cys11, is sourced from Porcine, Rat and Rabbit and is available as a 0.1mg vial. It can be use as a research tool for studying the function of endothelin receptors.

Formula: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Purezza: Min. 95%

Peso molecolare: 2,643 g/mol

Ref: 3D-PED-4199-S

Endothelin 3, human, rat

CAS: 117399-93-6

Custom research peptide; min purity 95%.

Formula: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Purezza: Min. 95%

Peso molecolare: 2,643.1 g/mol

Ref: 3D-PE16957

(3S)-3-[[(2S)-2-[[(2S)-2-[[(1R,4S,7S,10S,13S,16S,19S,22S,25R,28S,31R,36R,39S,42S,45S)-31-amino-7,13-bis(4-aminobutyl)-22-benzyl-4-(2 -carboxyethyl)-10-(carboxymethyl)-19,28-bis[(1R)-1-hydroxyethyl]-16,39,42-tris[(4-hydroxyphenyl)methyl]-3,6,9,12,15,18,21,

CAS: 117399-93-6

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Peso molecolare: 2,643.1 g/mol

Ref: 3D-PP50516

Endothelin-3 (human, mouse, rabbit, rat) trifluoroacetate salt

CAS: 117399-93-6

Trifluoroacetate salt

Formula: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Purezza: Min. 95%

Peso molecolare: 2,643.05 g/mol

Ref: 3D-FE110256