CAS 119425-90-0

LOUREIRIN B

Descrizione:

LOUREIRIN B è un composto naturale classificato come flavonoide, specificamente un tipo di flavanone, derivato dalla pianta brasiliana conosciuta come "Loureiro" (Licaria puechiana). È caratterizzato dalla sua struttura chimica unica, che include più gruppi idrossilici e uno scheletro di flavonoide, contribuendo alle sue potenziali attività biologiche. LOUREIRIN B ha suscitato interesse nella ricerca farmacologica a causa delle sue presunte proprietà antiossidanti, anti-infiammatorie e antimicrobiche. Gli studi suggeriscono che potrebbe mostrare effetti protettivi contro lo stress ossidativo e potrebbe avere implicazioni nel trattamento di varie malattie. Inoltre, si sta esplorando il suo potenziale ruolo nella modulazione delle vie di segnalazione cellulare. Come molti composti naturali, la biodisponibilità e l'efficacia di LOUREIRIN B nelle applicazioni terapeutiche sono oggetto di ricerca in corso. Il suo numero CAS, 119425-90-0, funge da identificatore unico per questo composto nelle banche dati chimiche, facilitando il suo studio e applicazione in vari campi scientifici.

Formula: C₁₈H₂₀O₅

InChI: InChI=1/C18H20O5/c1-21-14-10-17(22-2)15(18(11-14)23-3)8-9-16(20)12-4-6-13(19)7-5-12/h4-7,10-11,19H,8-9H2,1-3H3

InChI key: InChIKey=ZPFRAPVRYLGYEC-UHFFFAOYSA-N

SMILES: C(CC(=O)C1=CC=C(O)C=C1)C2=C(OC)C=C(OC)C=C2OC

Sinonimi:

• 1-(4-Hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)-1-propanone
• 1-(4-Hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)propan-1-one
• 1-Propanone, 1-(4-hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)-
• 4′-Hydroxy-2,4,6-trimethoxydihydrochalcone
• Lr-B
• Propan-1-one, 1-(4-hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)-
• Loureirin B
• Loureirin B
• cochinchinenin B
• LOUREIRIN B USP/EP/BP
• Loureirin B, 98%, from Dracaena cochinchinensis (Lour.) S. C. Chen

1-Propanone, 1-(4-hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)-

CAS: 119425-90-0

Formula: C₁₈H₂₀O₅

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 316.3484

Ref: IN-DA000IQR

Loureirin B

CAS: 119425-90-0

Loureirin B

Formula: C₁₈H₂₀O₅

Purezza: ≥98%

Peso molecolare: 316.35

Ref: 54-BUP02907

1-(4-Hydroxyphenyl)-3-(2,4,6-Trimethoxyphenyl)Propan-1-One

CAS: 119425-90-0

1-(4-Hydroxyphenyl)-3-(2,4,6-Trimethoxyphenyl)Propan-1-One

Formula: C₁₈H₂₀O₅

Purezza: 99%

Peso molecolare: 316.35

Ref: 54-OR1022890

Loureirin B

CAS: 119425-90-0

Formula: C₁₈H₂₀O₅

Peso molecolare: 316.35

Ref: 7W-GY0402

Loureirin B

CAS: 119425-90-0

Loureirin B, a flavonoid extracted from Dracaena cochinchinensis, is an inhibitor of plasminogen activator inhibitor-1 (PAI-1), with an IC50 of 26.10 μM; Loureirin B also inhibits KATP, the phosphorylation of ERK and JNK, and has anti-diabetic activity.Loureirin B inhibits fibroblast proliferation and extracellular matrix deposition in hypertrophic scar via TGF-β/Smad pathway, loureirin B can suppress tetrodotoxin-sensitive (TTX-S) voltage-gated sodium currents in a dose-dependent way.

Formula: C₁₈H₂₀O₅

Purezza: 95%~99%

Peso molecolare: 316.353

Ref: BP-BP0885

Loureirin B (Standard)

CAS: 119425-90-0

Loureirin B (Standard) is a reference standard for research and analysis in studies involving Loureirin B. Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved.

Formula: C₁₈H₂₀O₅

Peso molecolare: 316.3484

Ref: TM-TMSM-2459

Loureirin B

CAS: 119425-90-0

1-(4-Hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)propan-1-one

Formula: C₁₈H₂₀O₅

Purezza: 99%

Peso molecolare: 316.35

Ref: IN-DG136704

Loureirin B

CAS: 119425-90-0

Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.

Formula: C₁₈H₂₀O₅

Purezza: 99.33% - 99.86%

Colore e forma: White Solid

Peso molecolare: 316.3484

Ref: TM-T3876

Loureirin B

CAS: 119425-90-0

Ketone phenol

Formula: C₁₈H₂₀O₅

Purezza: ≥ 98.0 % (HPLC)

Peso molecolare: 316.35

Ref: 5G-84235

Loureirin B

CAS: 119425-90-0

Loureirin B is a natural polyphenolic compound, which is derived from the resin of Dracaena cochinchinensis, commonly known as Dragon's Blood. This compound exhibits its mode of action primarily through the inhibition of key inflammatory pathways, including the suppression of cyclooxygenase-2 (COX-2) and the reduction of pro-inflammatory cytokines. Such mechanisms suggest its potential in modulating inflammatory responses effectively.

Formula: C₁₈H₂₀O₅

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 316.35 g/mol

Ref: 3D-FL74520

Loureirin B

CAS: 119425-90-0

Formula: C₁₈H₂₀O₅

Peso molecolare: 316.3

Ref: BE-RMT13190