CAS 1195941-38-8

SAR-100842

CAS: 1195941-38-8

2-(4-Methoxy-3-(3-methylphenethoxy)benzamido)-2,3-dihydro-1H-indene-2-carboxylic acid

Formula: C₂₇H₂₇NO₅

Purezza: 98%

Peso molecolare: 445.51

Ref: IN-DG629192

Edg-2 receptor inhibitor 1

CAS: 1195941-38-8

Edg-2 receptor inhibitor 1 (SAR-100842) is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM).

Formula: C₂₇H₂₇NO₅

Purezza: 99.47%

Colore e forma: Solid

Peso molecolare: 445.51

Ref: TM-T4521

Edg-2 receptor inhibitor 1

CAS: 1195941-38-8

Edg-2 receptor inhibitor 1

Formula: C₂₇H₂₇NO₅

Purezza: ≥98%

Peso molecolare: 445.51

Ref: 54-BUP05601

2,3-Dihydro-2-[[4-methoxy-3-[2-(3-methylphenyl)ethoxy]benzoyl]amino]-1H-Indene-2-carboxylic Acid

CAS: 1195941-38-8

2,3-Dihydro-2-[[4-methoxy-3-[2-(3-methylphenyl)ethoxy]benzoyl]amino]-1H-Indene-2-carboxylic Acid (MK0893) is a small molecule that belongs to the class of indole carboxamides. It is a potent and selective inhibitor of phosphodiesterase 1 (PDE1), with an IC50 value of less than 10 nM. MK0893 inhibits PDE1 in vitro and in vivo, leading to increased cAMP levels, vasodilation, and induction of nitric oxide synthase. MK0893 has been shown to have therapeutic efficacy in animal models of systemic sclerosis. In these models, MK0893 inhibited the development of skin fibrosis by inhibiting TGFβ signaling, which is implicated in the pathogenesis of systemic sclerosis.

Formula: C₂₇H₂₇NO₅

Purezza: Min. 95%

Peso molecolare: 445.51 g/mol

Ref: 3D-VXB94138