CAS 1227163-84-9

Formula: C24H16F3N5

InChI: InChI=1S/C24H16F3N5/c25-19-6-2-5-18-21(19)23(28)32-24(18,17-7-8-31-20(10-17)22(26)27)16-4-1-3-14(9-16)15-11-29-13-30-12-15/h1-13,22H,(H2,28,32)/t24-/m0/s1

InChI key: MRXBCEQZNKUUIP-DEOSSOPVSA-N

SMILES: C1=CC(=CC(=C1)[C@@]2(C3=C(C(=CC=C3)F)C(=N2)N)C4=CC(=NC=C4)C(F)F)C5=CN=CN=C5

AZD3839 free base

CAS: 1227163-84-9

AZD3839 free base

Formula: C₂₄H₁₆F₃N₅

Purezza: ≥98%

Peso molecolare: 431.41

Ref: 54-BUP00224

(S)-1-(2-(Difluoromethyl)pyridin-4-yl)-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine

CAS: 1227163-84-9

Formula: C₂₄H₁₆F₃N₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 431.4125

Ref: IN-DA009CMV

(S)-1-(2-(difluoromethyl)pyridin-4-yl)-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine

CAS: 1227163-84-9

Purezza: 98%

Peso molecolare: 431.4219971

Ref: 10-F866411

AZD3839

CAS: 1227163-84-9

AZD3839 is a potent and selective inhibitor of the enzyme factor Xa. This drug has been shown to be effective in animal models of hypopigmentation and diseases related to muscle function. AZD3839 inhibits the activity of factor Xa by binding to the active site, preventing its proteolytic cleavage of factors Va and VIIIa. The inhibition of factor Xa prevents the production of thrombin, which is responsible for blood clotting. In humans, AZD3839 has been shown to have no effect on platelet aggregation or bleeding time. Clinical trials are ongoing to determine whether AZD3839 will be effective in treating human liver disease caused by antithrombotic drugs (e.g., warfarin).

Formula: C₂₄H₁₆F₃N₅

Purezza: Min. 95%

Peso molecolare: 431.41 g/mol

Ref: 3D-CZB16384

AZD3839 free base

CAS: 1227163-84-9

AZD3839 free base is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.

Formula: C₂₄H₁₆F₃N₅

Purezza: 99.93% - 99.96%

Colore e forma: White Solid

Peso molecolare: 431.4125

Ref: TM-T6772