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CAS 1229194-11-9
:Ethanodiamide, N1-(5-cloro-2-piridinil)-N2-[(1S,2R,4S)-4-[(dimetilamino)carbonil]-2-[[(4,5,6,7-tetraidro-5-metiltiazolo[5,4-c]piridin-2-il)carbonil]amino]cicloesil]-, 4-metilbenzensulfonato, idrato (1:1:1)
Descrizione:
Ethanodiamide, N1-(5-cloro-2-piridinil)-N2-[(1S,2R,4S)-4-[(dimetilamino)carbonil]-2-[[(4,5,6,7-tetraidro-5-metiltiazolo[5,4-c]piridin-2-il)carbonil]amino]cicloesil]-, 4-metilbenzensulfonato, idrato (1:1:1) è un composto organico complesso caratterizzato dalla sua struttura multifunzionale, che include uno scheletro di etanediamide e vari sostituenti che contribuiscono alla sua attività biologica. La presenza di un gruppo cloro e di un anello di piridina suggerisce interazioni potenziali con bersagli biologici, rendendolo di interesse nella chimica medicinale. Il composto presenta anche una porzione di tiazolo, spesso associata a proprietà farmacologiche. Il gruppo sulfonato migliora la sua solubilità in ambienti acquosi, il che è vantaggioso per applicazioni biologiche. Come idrato, contiene molecole d'acqua che possono influenzare la sua stabilità e solubilità. In generale, la struttura intricata e i gruppi funzionali di questo composto indicano una potenziale utilità nello sviluppo di farmaci, in particolare nel targeting di specifiche vie biologiche o recettori. Ulteriori studi sarebbero necessari per chiarire i suoi meccanismi d'azione precisi e il potenziale terapeutico.
Formula:C24H30ClN7O4S·C7H8O3S·H2O
InChI:InChI=1S/C24H30ClN7O4S.C7H8O3S.H2O/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23;1-6-2-4-7(5-3-6)11(8,9)10;/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34);2-5H,1H3,(H,8,9,10);1H2/t13-,15-,17+;;/m0../s1
InChI key:InChIKey=PSMMNJNZVZZNOI-SJILXJHISA-N
SMILES:N(C(=O)C1=NC2=C(S1)CN(C)CC2)[C@H]3[C@@H](NC(C(NC4=CC=C(Cl)C=N4)=O)=O)CC[C@H](C(N(C)C)=O)C3.S(=O)(=O)(O)C1=CC=C(C)C=C1.O
Sinonimi:- Edoxaban Tosylate Monohydrate
- Edoxaban tosylate hydrate
- Edoxaban4-methylbenzenesulfonate, hydrate (1:1:1)
- Ethanediamide, N<sup>1</sup>-(5-chloro-2-pyridinyl)-N<sup>2</sup>-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate, hydrate (1:1:1)
- N-(5-Chloropyridin-2-yl)-N′-((1S,2R,4S)-4-[(dimethyl amino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl)ethanediamide p-toluenesulfonate monohydrate
- N-(5-Chloropyridin-2-yl)-N′-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide mono(p-toluenesulfonate) monohydrate
- Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate, hydrate (1:1:1)
- Edoxaban tosylate monohydrate(for Edoxaban)
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Trovati 8 prodotti.
Edoxaban Tosylate
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C24H30ClN7O4S·C7H8O3S·H2OColore e forma:White Off-White PowderPeso molecolare:547.17685Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate, hydrate (1:1:1)
CAS:Formula:C31H40ClN7O8S2Purezza:%Colore e forma:SolidPeso molecolare:738.2744Edoxaban Tosylate Monohydrate
CAS:Edoxaban Tosylate MonohydrateFormula:C31H40ClN7O8S2Purezza:≥98%Peso molecolare:738.27N1-(5-Chloropyridin-2-Yl)-N2-((1S,2R,4S)-4-(Dimethylcarbamoyl)-2-(5-Methyl-4,5,6,7-Tetrahydrothiazolo[5,4-C]Pyridine-2-Carboxamido)Cyclohexyl)Oxalamide 4-Methylbenzenesulfonate Hydrate
CAS:N1-(5-Chloropyridin-2-Yl)-N2-((1S,2R,4S)-4-(Dimethylcarbamoyl)-2-(5-Methyl-4,5,6,7-Tetrahydrothiazolo[5,4-C]Pyridine-2-Carboxamido)Cyclohexyl)Oxalamide 4-Methylbenzenesulfonate HydrateFormula:C31H40ClN7O8S2Purezza:≥98%Peso molecolare:738.27Edoxaban Tosylate Monohydrate
CAS:Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Formula:C31H40ClN7O8S2Purezza:99.86% - 99.91%Colore e forma:SolidPeso molecolare:738.27Ref: ST-EA-CP-E8017
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaEdoxaban Tosylate Monohydrate
CAS:Applications Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor.
References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)Formula:C31H38ClN7O7S2•xH2OColore e forma:NeatPeso molecolare:720.26Edoxaban tosylate hydrate
CAS:Edoxaban tosylate hydrate is an anticoagulant that inhibits the activity of thrombin and factor Xa. It has a long half-life and does not undergo significant first-pass metabolism in the liver. Edoxaban tosylate hydrate is used for the prevention of stroke in patients with atrial fibrillation. It can be administered orally or by intravenous infusion, and its effect is monitored by measuring levels of the natriuretic peptide NT-proBNP. Edoxaban tosylate hydrate has a low potential for drug interactions, which may be due to its low protein binding affinity (less than 10%). This drug also inhibits P-glycoprotein, which may lead to bleeding complications.
Formula:C24H30ClN7O4S·C7H8O3S·H2OPurezza:Min. 95%Peso molecolare:738.28 g/mol
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