CAS 1253573-53-3

Formula: C22H28FN9O3S

InChI: InChI=1S/C22H28FN9O3S/c1-13(31-5-7-32(8-6-31)36(4,33)34)15-9-17(20-27-14(2)28-22(24)30-20)19(25-11-15)29-16-10-18(23)21(35-3)26-12-16/h9-13H,5-8H2,1-4H3,(H,25,29)(H2,24,27,28,30)/t13-/m1/s1

InChI key: KUGIFHQBIIHRIZ-CYBMUJFWSA-N

SMILES: CC1=NC(=NC(=N1)N)C2=C(N=CC(=C2)[C@@H](C)N3CCN(CC3)S(=O)(=O)C)NC4=CC(=C(N=C4)OC)F

(R)-4-(2-((5-Fluoro-6-methoxypyridin-3-yl)amino)-5-(1-(4-(methylsulfonyl)piperazin-1-yl)ethyl)pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine

CAS: 1253573-53-3

(R)-4-(2-((5-Fluoro-6-methoxypyridin-3-yl)amino)-5-(1-(4-(methylsulfonyl)piperazin-1-yl)ethyl)pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine

Formula: C₂₂H₂₈FN₉O₃S

Purezza: 98%

Peso molecolare: 517.59

Ref: 54-PC1007700

AMG 511

CAS: 1253573-53-3

Formula: C₂₂H₂₈FN₉O₃S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 517.5796

Ref: IN-DA01E0NA

AMG 511

CAS: 1253573-53-3

(R)-4-(2-((5-Fluoro-6-methoxypyridin-3-yl)amino)-5-(1-(4-(methylsulfonyl)piperazin-1-yl)ethyl)pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine

Formula: C₂₂H₂₈FN₉O₃S

Purezza: 98%

Peso molecolare: 517.58

Ref: IN-DG01258350

AMG 511

CAS: 1253573-53-3

AMG 511: oral class I PI3K inhibitor (α, β, δ, γ Kis: 4, 6, 2, 1 nM), anti-tumor in mouse glioblastoma model, reduces p-Akt (Ser473).

Formula: C₂₂H₂₈FN₉O₃S

Purezza: ≥98%

Colore e forma: Solid

Peso molecolare: 517.58

Ref: TM-T14214

AMG-511

Prodotto controllato

CAS: 1253573-53-3

Formula: C₂₂H₂₈FN₉O₃S

Colore e forma: Neat

Peso molecolare: 517.58

Ref: TR-A576580

AMG-511

CAS: 1253573-53-3

AMG-511 is a drug that inhibits the activity of growth factors, such as vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF), which are important for the development of cancer. AMG-511 has been shown to inhibit endothelial cell proliferation in vitro and tumor growth in vivo. It also has anti-apoptotic effects in human cells. AMG-511 is a small molecule inhibitor that targets proteins involved in inflammation, including toll-like receptor 4.

Formula: C₂₁H₂₆FN₉O₃S

Purezza: Min. 95%

Peso molecolare: 503.55 g/mol

Ref: 3D-DAC57353