CAS 1254036-71-9

Formula: C26H28N6O

InChI: InChI=1S/C26H28N6O/c1-17(2)32-10-8-31(9-11-32)16-19-14-28-26(33-19)22-12-18(13-25-23(22)15-29-30-25)20-4-3-5-24-21(20)6-7-27-24/h3-7,12-15,17,27H,8-11,16H2,1-2H3,(H,29,30)

InChI key: MCIDWGZGWVSZMK-UHFFFAOYSA-N

SMILES: CC(C)N1CCN(CC1)CC2=CN=C(O2)C3=C4C=NNC4=CC(=C3)C5=C6C=CNC6=CC=C5

Nemiralisib

CAS: 1254036-71-9

Nemiralisib

Formula: C₂₆H₂₈N₆O

Purezza: 99.5%

Peso molecolare: 440.54

Ref: 54-BUP02013

1H-Indazole, 6-(1H-indol-4-yl)-4-[5-[[4-(1-methylethyl)-1-piperazinyl]methyl]-2-oxazolyl]-

CAS: 1254036-71-9

Formula: C₂₆H₂₈N₆O

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 440.5401

Ref: IN-DA000NMT

2-(6-(1H-Indol-4-yl)-1H-indazol-4-yl)-5-((4-isopropylpiperazin-1-yl)methyl)oxazole

CAS: 1254036-71-9

2-(6-(1H-Indol-4-yl)-1H-indazol-4-yl)-5-((4-isopropylpiperazin-1-yl)methyl)oxazole

Formula: C₂₆H₂₈N₆O

Purezza: 98%

Peso molecolare: 440.54

Ref: IN-DG559294

Nemiralisib

CAS: 1254036-71-9

Nemiralisib is a small molecule that inhibits the PD-L1 protein. It can be used to treat cancer and autoimmune diseases. Nemiralisib binds to the PD-L1 protein and prevents it from binding to its ligands, CD80 or CD86. This prevents the immune system from being suppressed by the PD-L1 protein and may enable an anti-PD-L1 therapy to induce tumor regression in patients with cancer. Nemiralisib has been shown to inhibit P-glycoprotein (Pgp) activity in vitro, which may result in drug interactions with other drugs that are substrates of this transporter. Nemiralisib has a terminal half life of approximately 6 hours, meaning that most of it will be eliminated from the body within 24 hours after administration. The chemical name for nemiralisib is 1-[3-(4-chlorophenyl)phenyl]-3-[2-(methylsulfonyl)phenyl]urea. The

Formula: C₂₆H₂₈N₆O

Purezza: Min. 95%

Peso molecolare: 440.54 g/mol

Ref: 3D-EAC03671

Nemiralisib

CAS: 1254036-71-9

Nemiralisib (GSK-2269557) is an oral PI3Kδ inhibitor (pKi 9.9) for treating respiratory diseases like COPD.

Formula: C₂₆H₂₈N₆O

Purezza: 99.91%

Colore e forma: Solid

Peso molecolare: 440.5401

Ref: TM-T15431