CAS 1258417-54-7

Formula: C20H18F2N6O3

InChI: InChI=1S/C20H18F2N6O3/c1-11-5-4-6-13(7-11)18-17(24-12(2)31-18)19(29)26-15-8-23-28(27-15)9-16-25-14(10-30-16)20(3,21)22/h4-8,10H,9H2,1-3H3,(H,26,27,29)

InChI key: PBTWPEDVIMHJEO-UHFFFAOYSA-N

SMILES: CC1=CC(=CC=C1)C2=C(N=C(O2)C)C(=O)NC3=NN(N=C3)CC4=NC(=CO4)C(C)(F)F

ACT-389949

CAS: 1258417-54-7

ACT-389949

Formula: C₂₀H₁₈F₂N₆O₃

Purezza: ≥95%

Peso molecolare: 428.39

Ref: 54-BUP00479

ACT-389949

CAS: 1258417-54-7

ACT-389949: Potent, selective FPR2/ALX agonist; EC50 3 nM; potential inflammatory disorder treatment.

Formula: C₂₀H₁₈F₂N₆O₃

Purezza: 99.4%

Colore e forma: White Solid

Peso molecolare: 428.3921

Ref: TM-T10242

N-(2-((4-(1,1-Difluoroethyl)Oxazol-2-Yl)Methyl)-2H-1,2,3-Triazol-4-Yl)-2-Methyl-5-(M-Tolyl)Oxazole-4-Carboxamide

CAS: 1258417-54-7

N-(2-((4-(1,1-Difluoroethyl)Oxazol-2-Yl)Methyl)-2H-1,2,3-Triazol-4-Yl)-2-Methyl-5-(M-Tolyl)Oxazole-4-Carboxamide

Formula: C₂₀H₁₈F₂N₆O₃

Purezza: 98%

Peso molecolare: 428.39

Ref: 54-PC108497

N-(2-((4-(1,1-Difluoroethyl)oxazol-2-yl)methyl)-2H-1,2,3-triazol-4-yl)-2-methyl-5-(m-tolyl)oxazole-4-carboxamide

CAS: 1258417-54-7

Formula: C₂₀H₁₈F₂N₆O₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 428.3921

Ref: IN-DA01N18B

ACT-389949

CAS: 1258417-54-7

N-(2-((4-(1,1-Difluoroethyl)oxazol-2-yl)methyl)-2H-1,2,3-triazol-4-yl)-2-methyl-5-(m-tolyl)oxazole-4-carboxamide

Formula: C₂₀H₁₈F₂N₆O₃

Purezza: 98%

Peso molecolare: 428.39

Ref: IN-DG01261631

ACT-389949

CAS: 1258417-54-7

ACT-389949 is a novel small molecule that has been shown to be a potent inhibitor of neutrophil recruitment. It has been shown to inhibit the chemotaxis of neutrophils and leukocytes in vitro by binding to granule proteins and preventing their release. ACT-389949 is an orally active, potent, selective, and reversible inhibitor of neutrophil recruitment with a terminal half-life of approximately 24 hours. The pharmacodynamics of this drug are dose-dependent with an EC50 value at the lower end of the therapeutic window. This profile may explain why it is effective in patients who have been exposed to other drugs that are ineffective due to resistance. In addition, ACT-389949 does not induce any known inflammatory cytokines or act as an immunosuppressant.

Formula: C₂₀H₁₈F₂N₆O₃

Purezza: Min. 95%

Peso molecolare: 428.4 g/mol

Ref: 3D-IAC41754