CAS 130-95-0

Chinina

Descrizione:

Chinina è un alcaloide che si trova naturalmente nella corteccia dell'albero della china, noto principalmente per le sue proprietà antimalariche. Ha una struttura chimica complessa caratterizzata da un sistema ad anello biciclico, che include un moiety di quiniclidina e un moiety di chinolina. Chinina è tipicamente una polvere cristallina bianca solubile in acqua e ha un sapore amaro, motivo per cui è stato storicamente utilizzato per aromatizzare l'acqua tonica. La sua formula chimica è C20H24N2O2 e presenta una gamma di effetti farmacologici, comprese le proprietà analgesiche e antipiretiche. Chinina agisce interferendo con la capacità del parassita di metabolizzare e utilizzare l'emoglobina, rendendolo efficace contro la malaria. Inoltre, è stato studiato per il suo potenziale utilizzo nel trattamento dei crampi notturni alle gambe e di alcune aritmie cardiache. Tuttavia, a causa dei suoi effetti collaterali, incluso il cinchonismo, viene utilizzato con cautela in contesti clinici. Il numero CAS di Chinina è 130-95-0, che identifica in modo univoco questo composto nelle banche dati chimiche.

Formula: C₂₀H₂₄N₂O₂

InChI: InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1

InChI key: InChIKey=LOUPRKONTZGTKE-WZBLMQSHSA-N

SMILES: [C@@H](O)(C=1C2=C(C=CC(OC)=C2)N=CC1)[C@]3([N@@]4C[C@H](C=C)[C@](C3)(CC4)[H])[H]

Sinonimi:

• (3alpha,4beta,9S)-6'-methoxycinchonan-9-ol
• (3alpha,9S)-6'-methoxycinchonan-1-ium-9-ol
• (4beta,8alpha,9R)-6'-methoxycinchonan-1-ium-9-ol
• (4beta,9R)-6'-methoxycinchonan-9-ol
• (6-Methoxy-4-quinolyl)(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol
• (8S,9R)-Quinine
• (8alpha,9R)-6'-methoxycinchonan-9-ol
• (8alpha,9R)-9-hydroxy-6'-methoxycinchonan-1-ium
• (8α,9R)-6'-Methoxycinchonan-9-ol
• (9R)-6'-methoxycinchonan-9-ol sulfate (salt)
• (R)-(-)-Quinine
• (R)-(6-Methoxy-4-quinolyl)[(2S)-5-vinylquinuclidin-2-yl]methanol
• 6'-Methoxycinchonan-9-Ol
• 6'-Methoxycinchonidine
• Chinin
• Chinine
• Cinchonan-9-ol, 6'-methoxy-, (8α,9R)-
• Cinkona
• Mosgard
• Nsc 192949
• Qualaquin
• Quine 9
• Quinex
• Quinina
• Quinine anhydrous
• Quinine free base
• Quinlex
• Quinlup
• Rezquin
• Sw 85833
• Wr297608
• (-)-Quinine

Quinine

CAS: 130-95-0

Formula: C₂₀H₂₄N₂O₂

Purezza: >98.0%(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 324.42

Ref: 3B-Q0028

Quinine, anhydrous, 99% (total base), may cont. up to 5% dihydroquinine

CAS: 130-95-0

Quinine is used in photochemistry as a common fluorescence standard and as a resolving agent for chiral acids. It is also useful for treating falciparum malaria, lupus, arthritis and vivax malaria. It acts as a flavor component in tonic water and bitter lemon. It is utilized as the chiral moiety for

Formula: C₂₀H₂₄N₂O₂

Purezza: 99%

Colore e forma: Powder, White

Peso molecolare: 324.42

Ref: 02-A10459

Quinine

CAS: 130-95-0

Quinine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₂₀H₂₄N₂O₂

Purezza: (HPLC) ≥90%

Colore e forma: Powder

Peso molecolare: 324.42

Ref: 11-0610

Cinchonan-​9-​ol, 6'-​methoxy-​, (8α,​9R)​-

CAS: 130-95-0

Formula: C₂₀H₂₄N₂O₂

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 324.4168

Ref: IN-DA000TUZ

Quinine

CAS: 130-95-0

Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria.

Formula: C₂₀H₂₄N₂O₂

Purezza: 99.93% - 99.97%

Colore e forma: White Solid Powder

Peso molecolare: 324.42

Ref: TM-T0690

(R)-[(2S,4S,5R)-1-Aza-5-vinylbicyclo[2.2.2]oct-2-yl](6-methoxyquinolin-4-yl)methanol

CAS: 130-95-0

(R)-[(2S,4S,5R)-1-Aza-5-vinylbicyclo[2.2.2]oct-2-yl](6-methoxyquinolin-4-yl)methanol

Formula: C₂₀H₂₄N₂O₂

Purezza: 97%

Colore e forma: Off-white Solid-Powder

Peso molecolare: 324.41676

Ref: 54-OR28880

Quinine

CAS: 130-95-0

Formula: C₂₀H₂₄N₂O₂

Colore e forma: White To Off-White Solid

Peso molecolare: 324.43

Ref: 4Z-Q-034

Quinine

CAS: 130-95-0

Quinine

Formula: C₂₀H₂₄N₂O₂

Purezza: ≥90%

Peso molecolare: 324.42

Ref: 54-BUP18386

(R)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol

CAS: 130-95-0

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 324.4240112

Ref: 10-F869567

Quinine

Prodotto controllato

CAS: 130-95-0

Formula: C₂₀H₂₄N₂O₂

Colore e forma: Neat

Peso molecolare: 324.42

Ref: 04-C16706900

Quinine, anhydrous

CAS: 130-95-0

Formula: C₂₀H₂₄N₂O₂

Purezza: ≥ 96.0%

Colore e forma: White to off-white powder or crystals

Peso molecolare: 324.42

Ref: 7W-GE6508

(-)-Quinine

CAS: 130-95-0

Cinchona alkaloid

Formula: C₂₀H₂₄N₂O₂

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 324.42

Ref: 5G-80962

Quinine

Prodotto controllato

CAS: 130-95-0

Applications Primary alkaloid of various species of Cinchona (Rubiaceae). Optical isomer of Quinidine. Antimalarial; muscle relaxant (skeletal).
References Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 12, 547 (1983), Kremsner, P.G., et al.: J. Infect. Dis., 169, 467 (1994),

Formula: C₂₀H₂₄N₂O₂

Colore e forma: Neat

Peso molecolare: 324.42

Ref: TR-Q694000

(R)-(6-Methoxyquinolin-4-yl)((1R,2R,4R,5S)-5-vinylquinuclidin-2-yl)methanol

CAS: 130-95-0

Formula: C₂₀H₂₄N₂O₂

Purezza: 96%

Peso molecolare: 324.424

Ref: 10-F236843

Quinine

CAS: 130-95-0

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 324.18

Ref: 10-F858759

Quinine

CAS: 130-95-0

Formula: C₂₀H₂₄N₂O₂

Peso molecolare: 324.42

Ref: ST-EA-CP-Q3000

Quinidine EP Impurity A

CAS: 130-95-0

Formula: C₂₀H₂₄N₂O₂

Peso molecolare: 324.42

Ref: ST-EA-CP-Q9002

(6-Methoxy-4-quinolyl)(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol

CAS: 130-95-0

6-Methoxy-4-quinolyl)(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol is a positron emission tomography (PET) radioligand that binds to the human cyp3a4 enzyme and is used in the study of drug interactions. This molecule has an inhibitory effect on the NADPH cytochrome P450 enzyme and cellular membranes, leading to cell death. 6-Methoxy-4-quinolyl)(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol has been shown to be an analog of quinine, a drug used in the treatment of malaria and some other infectious diseases.

Formula: C₂₀H₂₄N₂O₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 324.42 g/mol

Ref: 3D-FM27379