CAS 131189-57-6

Cornuside

Descrizione:

Cornuside, con il numero CAS 131189-57-6, è un composto naturale derivato principalmente dalle specie di Cornus, in particolare dall'albero del corniolo. È classificato come un glicoside flavonoide, il che significa che consiste in una parte flavonoide legata a una molecola di zucchero. Cornuside è noto per le sue potenziali proprietà farmacologiche, inclusi effetti antinfiammatori, antiossidanti e neuroprotettivi. La sua struttura presenta tipicamente uno scheletro flavonoide, che contribuisce alla sua attività biologica e interazione con varie vie cellulari. La ricerca ha indicato che Cornuside potrebbe svolgere un ruolo nella modulazione dello stress ossidativo e dell'infiammazione, rendendolo di interesse nel contesto di varie condizioni di salute. Inoltre, la sua presenza nella medicina tradizionale evidenzia la sua importanza storica e le potenziali applicazioni terapeutiche. Tuttavia, sono necessari ulteriori studi per chiarire completamente i suoi meccanismi d'azione e l'efficacia in contesti clinici. Come molti composti naturali, le caratteristiche specifiche, inclusa la solubilità e la stabilità, possono variare in base alle condizioni ambientali e al metodo di estrazione.

Formula: C₂₄H₃₀O₁₄

InChI: InChI=1S/C24H30O14/c1-3-11-12(4-5-35-21(32)10-6-14(26)17(28)15(27)7-10)13(22(33)34-2)9-36-23(11)38-24-20(31)19(30)18(29)16(8-25)37-24/h3,6-7,9,11-12,16,18-20,23-31H,1,4-5,8H2,2H3

InChI key: InChIKey=SMTKSCGLXONVGL-UHFFFAOYSA-N

SMILES: C(COC(=O)C1=CC(O)=C(O)C(O)=C1)C2C(C=C)C(OC3OC(CO)C(O)C(O)C3O)OC=C2C(OC)=O

Sinonimi:

• 2H-Pyran-5-carboxylic acid, 3-ethenyl-2-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-, methyl ester, (2S,3R,4S)-
• 2H-Pyran-5-carboxylic acid, 3-ethenyl-2-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-, methyl ester, [2S-(2α,3β,4β)]-
• Cornuside I
• Methyl (2R,3S,4R)-3-ethenyl-4-[2-(3,4,5-trihydroxybenzoyl)oxyethyl]-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydro-2H-pyran-5-carboxylate
• methyl (2R,3S,4R)-3-ethenyl-2-(beta-D-glucopyranosyloxy)-4-{2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl}-3,4-dihydro-2H-pyran-5-carboxylate
• 2H-Pyran-5-carboxylic acid, 3-ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-, methyl ester, [2S-(2α,3β,4β)]-
• Cornuside
• 2H-Pyran-5-carboxylic acid, 3-ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-, methyl ester, (2S,3R,4S)-

Comuside

CAS: 131189-57-6

Comuside

Formula: C₂₄H₃₀O₁₄

Purezza: 99%

Peso molecolare: 542.48659

Ref: 54-BISN0277

Cornuside

CAS: 131189-57-6

Formula: C₂₄H₃₀O₁₄

Peso molecolare: 542.49

Ref: 7W-GK2384

Cornuside

CAS: 131189-57-6

Cornuside

Formula: C₂₄H₃₀O₁₄

Purezza: ≥98%

Peso molecolare: 542.49

Ref: 54-BUP08489

Comuside

CAS: 131189-57-6

Formula: C₂₄H₃₀O₁₄

Purezza: 99%

Peso molecolare: 542.4866

Ref: IN-DA000VNU

Cornuside (Standard)

CAS: 131189-57-6

Cornuside (Standard) is a reference standard for research and analysis in studies involving Cornuside. 1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardial I/R and protect the liver from CCl4-induced acute hepatotoxicity, by reducing oxidative stress and suppressing inflammatory responses. 4. Cornuside has anti-inflammatory activity by downregulations of iNOS and COX-2 due to NF-κB inhibition as well as the negative regulation of ERK1/2, p38, and JNK1/2 phosphorylations in RAW 264.7 cells. 5. Cornuside has protective potential against cerebral ischemic injury, may be due to the suppression of intracellular Ca(2+) elevation and caspase-3 activity, and improvements in mitochondrial energy metabolism and antioxidant properties.

Formula: C₂₄H₃₀O₁₄

Peso molecolare: 542.4866

Ref: TM-TMSM-2765

Cornuside

CAS: 131189-57-6

Formula: C₂₄H₃₀O₁₄

Purezza: 95%~99%

Peso molecolare: 542.49

Ref: BP-BP0394

Cornuside

CAS: 131189-57-6

Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.

Formula: C₂₄H₃₀O₁₄

Purezza: 99.86% - >99.99%

Colore e forma: Solid

Peso molecolare: 542.4866

Ref: TM-T4S2326

Cornuside

CAS: 131189-57-6

(2S,3R,4S)-3-Ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-2H-pyran-5-carboxylic acid methyl ester

Formula: C₂₄H₃₀O₁₄

Purezza: 99%

Peso molecolare: 542.49

Ref: IN-DG01301000

Cornuside

CAS: 131189-57-6

Natural glycoside

Formula: C₂₄H₃₀O₁₄

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 542.49

Ref: 5G-83331

Cornuside

CAS: 131189-57-6

Cornuside is a natural compound that is found in the fruits of Cornus. It is a dihydrochalcone, which has been shown to have hypoglycemic effects and inhibit the activity of 5-hmf. Cornuside also inhibits the enzyme activities involved in energy metabolism, such as glucose-6-phosphate dehydrogenase and hexokinase. It has also been shown to have genotoxic properties and induce DNA damage. Cornuside may be useful for treating diabetes or cancer, but further research needs to be done before this can be confirmed.

Formula: C₂₄H₃₀O₁₄

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 542.49 g/mol

Ref: 3D-MC33273

Cornuside

CAS: 131189-57-6

Formula: C₂₄H₃₀O₁₄

Peso molecolare: 542.5

Ref: BE-RMT12842